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Q01WE6 (UPPP_SOLUE) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 54. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Undecaprenyl-diphosphatase

EC=3.6.1.27
Alternative name(s):
Bacitracin resistance protein
Undecaprenyl pyrophosphate phosphatase
Gene names
Name:uppP
Ordered Locus Names:Acid_5064
OrganismSolibacter usitatus (strain Ellin6076) [Complete proteome] [HAMAP]
Taxonomic identifier234267 [NCBI]
Taxonomic lineageBacteriaAcidobacteriaSolibacteresSolibacteralesSolibacteraceaeCandidatus Solibacter

Protein attributes

Sequence length275 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin By similarity. HAMAP-Rule MF_01006

Catalytic activity

Ditrans,octacis-undecaprenyl diphosphate + H2O = ditrans,octacis-undecaprenyl phosphate + phosphate. HAMAP-Rule MF_01006

Subcellular location

Cell inner membrane; Multi-pass membrane protein By similarity HAMAP-Rule MF_01006.

Miscellaneous

Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.

Sequence similarities

Belongs to the UppP family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 275275Undecaprenyl-diphosphatase HAMAP-Rule MF_01006
PRO_0000290769

Regions

Transmembrane1 – 2121Helical; Potential
Transmembrane40 – 6021Helical; Potential
Transmembrane85 – 10521Helical; Potential
Transmembrane117 – 13721Helical; Potential
Transmembrane189 – 20921Helical; Potential
Transmembrane224 – 24421Helical; Potential
Transmembrane251 – 27121Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q01WE6 [UniParc].

Last modified November 14, 2006. Version 1.
Checksum: C7B41E906A75725A

FASTA27530,095
        10         20         30         40         50         60 
MPILQVIVLA VVQGLTEFLP ISSTAHLYLT SWLLGWQIEG LDFDIALHIG TLLAVLIFFA 

        70         80         90        100        110        120 
RDWLQIIAQG FGIRREGDRE LNHNHMLLWL LLIGTVPVGI AGLLFNKQAE GAWRNPFVMG 

       130        140        150        160        170        180 
FMLIVVGVLM WIAENAGRQQ RDLSSLDLAD TLAIGTAQAL AVVPGTSRSG VTITAGLFRS 

       190        200        210        220        230        240 
LTRESAARFS FLLSTPAIGA AAAKAIWDMH KKGGGLHGML HADFLVGVAV SAITGCIVIA 

       250        260        270 
WFLHYLRRNG LRPFVYYRIL FGIIVLALAF IRRPA 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000473 Genomic DNA. Translation: ABJ86019.1.
RefSeqYP_826304.1. NC_008536.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING234267.Acid_5064.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABJ86019; ABJ86019; Acid_5064.
GeneID4426707.
KEGGsus:Acid_5064.
PATRIC32012676. VBICanSol30224_5299.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1968.
HOGENOMHOG000218357.
KOK06153.
OMAAQCFALI.
OrthoDBEOG6QP13M.

Enzyme and pathway databases

BioCycSUSI234267:GHSK-5105-MONOMER.

Family and domain databases

HAMAPMF_01006. Undec_diphosphatase.
InterProIPR003824. UppP.
[Graphical view]
PfamPF02673. BacA. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameUPPP_SOLUE
AccessionPrimary (citable) accession number: Q01WE6
Entry history
Integrated into UniProtKB/Swiss-Prot: June 12, 2007
Last sequence update: November 14, 2006
Last modified: February 19, 2014
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families