Q01V26 (Q01V26_SOLUE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Inorganic pyrophosphatase HAMAP MF_00209
EC=3.6.1.1 HAMAP MF_00209

Alternative name(s):
Pyrophosphate phospho-hydrolase HAMAP MF_00209

Gene names

Name:	ppa HAMAP MF_00209
Ordered Locus Names:	Acid_5542

Organism

Solibacter usitatus (strain Ellin6076) [Complete proteome] [HAMAP]

Taxonomic identifier

234267 [NCBI]

Taxonomic lineage

Bacteria › Acidobacteria › Solibacteres › Solibacterales › Solibacteraceae › Candidatus Solibacter

Protein attributes

Sequence length	191 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Diphosphate + H2O = 2 phosphate. HAMAP MF_00209
Cofactor	Binds 4 magnesium ions per subunit. Other metal ions can support activity, but at a lower rate. Two magnesium ions are required for the activation of the enzyme and are present before substrate binds, two additional magnesium ions form complexes with substrate and product By similarity. HAMAP MF_00209
Subcellular location	Cytoplasm By similarity HAMAP MF_00209.
Sequence similarities	Belongs to the PPase family. HAMAP MF_00209

Ontologies

Keywords
Cellular component	Cytoplasm HAMAP MF_00209
Ligand	Magnesium HAMAP MF_00209 Metal-binding HAMAP MF_00209
Molecular function	Hydrolase HAMAP MF_00209 EMBL ABJ86489.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	phosphate-containing compound metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	inorganic diphosphatase activity Inferred from electronic annotation. Source: HAMAP magnesium ion binding Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Metal binding	73	1	Magnesium 1 By similarity HAMAP MF_00209
	Metal binding	78	1	Magnesium 1 By similarity HAMAP MF_00209
	Metal binding	78	1	Magnesium 2 By similarity HAMAP MF_00209
	Metal binding	110	1	Magnesium 1 By similarity HAMAP MF_00209

Sequences

	Sequence		Length	Mass (Da)
	Q01V26 [UniParc]. Last modified November 14, 2006. Version 1. Checksum: 16F2102A24CF3E41	FASTA	191	21,921
	10 20 30 40 50 60 MRCYDSECMS LYDLEPGPDC PELVRMIVEI PKNSSNKYEY DGKLGVFRLD RSLYSAVHYP 70 80 90 100 110 120 GDYGFIPGTL AEDGDPLDVL TLVDVPSFPG VLMMVRPVGV LAMVDQEEPD EKILAVPNHN 130 140 150 160 170 180 PRFDQIHTID QVFQHNLREI EHFFAIYKEL EGKRTVMQGW KGPREARDVI RRSRERYLAA 190 HPELQLDPEA S

References

[1]

"Three genomes from the phylum Acidobacteria provide insight into the lifestyles of these microorganisms in soils." Ward N.L., Challacombe J.F., Janssen P.H., Henrissat B., Coutinho P.M., Wu M., Xie G., Haft D.H., Sait M., Badger J., Barabote R.D., Bradley B., Brettin T.S., Brinkac L.M., Bruce D., Creasy T., Daugherty S.C., Davidsen T.M. , DeBoy R.T., Detter J.C., Dodson R.J., Durkin A.S., Ganapathy A., Gwinn-Giglio M., Han C.S., Khouri H., Kiss H., Kothari S.P., Madupu R., Nelson K.E., Nelson W.C., Paulsen I., Penn K., Ren Q., Rosovitz M.J., Selengut J.D., Shrivastava S., Sullivan S.A., Tapia R., Thompson L.S., Watkins K.L., Yang Q., Yu C., Zafar N., Zhou L., Kuske C.R. Appl. Environ. Microbiol. 75:2046-2056(2009) [PubMed: 19201974] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000473 Genomic DNA. Translation: ABJ86489.1.
RefSeq	YP_826774.1. NC_008536.1.
3D structure databases
ProteinModelPortal	Q01V26.
ModBase	Search...
Protein-protein interaction databases
STRING	Q01V26.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4426232.
GenomeReviews	Gene locus Acid_5542 in contig CP000473_GR.
KEGG	sus:Acid_5542.
NMPDR	fig|234267.9.peg.5269.
PATRIC	32013683. VBICanSol30224_5799.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0221.
HOGENOM	HBG529150.
OMA	SESAHEA.
PhylomeDB	Q01V26.
Family and domain databases
HAMAP	MF_00209. Inorganic_PPase. [Tree]
InterPro	IPR008162. Pyrophosphatase. [Graphical view]
Gene3D	G3DSA:3.90.80.10. Pyrophosphatase. 1 hit.
KO	K01507.
PANTHER	PTHR10286. Pyrophosphatase. 1 hit.
Pfam	PF00719. Pyrophosphatase. 1 hit. [Graphical view]
SUPFAM	SSF50324. Pyrophosphatase. 1 hit.
PROSITE	PS00387. PPASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q01V26_SOLUE

Accession

Primary (citable) accession number: Q01V26

Entry history

Integrated into UniProtKB/TrEMBL:	November 14, 2006
Last sequence update:	November 14, 2006
Last modified:	December 14, 2011
This is version 27 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)