Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q01UL9 (Q01UL9_SOLUE) Unreviewed, UniProtKB/TrEMBL

Last modified November 13, 2013. Version 51. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein names
EC=2.3.3.13 EMBL ABJ86651.1
Gene names
Ordered Locus Names:Acid_5704 EMBL ABJ86651.1
OrganismSolibacter usitatus (strain Ellin6076) [Complete proteome] [HAMAP] EMBL ABJ86651.1
Taxonomic identifier234267 [NCBI]
Taxonomic lineageBacteriaAcidobacteriaSolibacteresSolibacteralesSolibacteraceaeCandidatus Solibacter

Protein attributes

Sequence length509 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) By similarity. SAAS SAAS013709

Catalytic activity

Acetyl-CoA + 3-methyl-2-oxobutanoate + H2O = (2S)-2-isopropylmalate + CoA.

Pathway

Amino-acid biosynthesis; L-leucine biosynthesis; L-leucine from 3-methyl-2-oxobutanoate: step 1/4. SAAS SAAS013709

Subunit structure

Homotetramer By similarity. SAAS SAAS013709

Sequences

Sequence LengthMass (Da)Tools
Q01UL9 [UniParc].

Last modified November 14, 2006. Version 1.
Checksum: 9E1E06EBC16D37E0

FASTA50954,439
        10         20         30         40         50         60 
MRDGEQAAGT RLGSREKLII ARQLALLNVD VIEAGYPNSS PEDFDAVQRI AAEIQGPAIC 

        70         80         90        100        110        120 
ALSRAVAADI EACGKALAGC PRPRIHTGIG ASDIHIAGKF QDDRYGKSLA EKKRKILQMA 

       130        140        150        160        170        180 
IDAVTLARHY VAEVEFYAED AGRADPVYLY EMIAAVIDAG ASVVNIPDTT GYTVPEQYGA 

       190        200        210        220        230        240 
LIAGIRTHVP GIDRAVISVH CHDDLGMAVA NTLHGVLNGA RQVEGTINGL GERAGNAALE 

       250        260        270        280        290        300 
EIVMALATRA DYFGVHTGVN TRELHRTSRL VADLLGVQVP PNKAVIGANA FSHSSGIHVD 

       310        320        330        340        350        360 
GVLKKRETYE IMRPEDVGMT ESRVVLTART GRHGLLDRLR KLGYELSDLE LDQAYRRFLS 

       370        380        390        400        410        420 
VADKKQEVFD EDLIAILRDE IHPLPAVYEL QYLHIYSGTS AIPTATVRLL VSGDTREGAA 

       430        440        450        460        470        480 
IGDGPVDAVC RAISQVTATA AKLQRYEIRG VTSGTEAMGE VTIQLEEAGR KVIGRGASTD 

       490        500 
IIEASAKAYL DGLNKLANIA AASHRSAGA 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000473 Genomic DNA. Translation: ABJ86651.1.
RefSeqYP_826936.1. NC_008536.1.

3D structure databases

ProteinModelPortalQ01UL9.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING234267.Acid_5704.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABJ86651; ABJ86651; Acid_5704.
GeneID4426079.
KEGGsus:Acid_5704.
PATRIC32014035. VBICanSol30224_5975.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0119.
HOGENOMHOG000046859.
KOK01649.
OMAXEITDAD.
OrthoDBEOG6CGCF3.

Enzyme and pathway databases

BioCycSUSI234267:GHSK-5747-MONOMER.
UniPathwayUPA00048; UER00070.

Family and domain databases

Gene3D3.20.20.70. 1 hit.
InterProIPR013709. 2-isopropylmalate_synth_dimer.
IPR002034. AIPM/Hcit_synth_CS.
IPR013785. Aldolase_TIM.
IPR005671. LeuA_bact_synth.
IPR000891. PYR_CT.
[Graphical view]
PfamPF00682. HMGL-like. 1 hit.
PF08502. LeuA_dimer. 1 hit.
[Graphical view]
SMARTSM00917. LeuA_dimer. 1 hit.
[Graphical view]
SUPFAMSSF110921. SSF110921. 1 hit.
TIGRFAMsTIGR00973. leuA_bact. 1 hit.
PROSITEPS00816. AIPM_HOMOCIT_SYNTH_2. 1 hit.
PS50991. PYR_CT. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ01UL9_SOLUE
AccessionPrimary (citable) accession number: Q01UL9
Entry history
Integrated into UniProtKB/TrEMBL: November 14, 2006
Last sequence update: November 14, 2006
Last modified: November 13, 2013
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)