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Q01TY5 (Q01TY5_SOLUE) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 42. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phosphoribosylformylglycinamidine synthase 2 HAMAP MF_00420
EC=6.3.5.3 HAMAP MF_00420
Alternative name(s):
Phosphoribosylformylglycinamidine synthase II HAMAP MF_00420
Gene names
Name:purL HAMAP MF_00420
Ordered Locus Names:Acid_5944
OrganismSolibacter usitatus (strain Ellin6076) [Complete proteome] [HAMAP]
Taxonomic identifier234267 [NCBI]
Taxonomic lineageBacteria › Acidobacteria › Solibacteres › Solibacterales › Solibacteraceae › Candidatus Solibacter

Protein attributes

Sequence length742 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide + L-glutamine + H2O = ADP + phosphate + 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine + L-glutamate. HAMAP MF_00420

Pathway

Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole from N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide: step 1/2. HAMAP MF_00420

Subunit structure

Heterodimer of two subunits, PurQ and PurL By similarity. HAMAP MF_00420

Subcellular location

Cytoplasm By similarity HAMAP MF_00420.

Sequence similarities

Belongs to the FGAMS family. HAMAP MF_00420

Ontologies

Keywords
   Biological processPurine biosynthesis HAMAP MF_00420
   Cellular componentCytoplasm HAMAP MF_00420
   LigandATP-binding HAMAP MF_00420
Nucleotide-binding
   Molecular functionLigase HAMAP MF_00420 EMBL ABJ86885.1
   Technical termComplete proteome
Gene Ontology (GO)
   Biological process'de novo' IMP biosynthetic process

Inferred from electronic annotation. Source: InterPro

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionATP binding

Inferred from electronic annotation. Source: HAMAP

phosphoribosylformylglycinamidine synthase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
Q01TY5 [UniParc].

Last modified November 14, 2006. Version 1.
Checksum: 3B559359D37E8C0D

FASTA74279,734
        10         20         30         40         50         60 
MSGTAAFSPE IIAQHQLTDG EYQKIVDILG REPSYTELGI FSVMWSEHCS YKSSRIHLKK 

        70         80         90        100        110        120 
LPTRGKLVVQ GPGENAGIID IGGGYVIAFK IESHNHPSFI EPFQGAATGV GGILRDIFTM 

       130        140        150        160        170        180 
GARPIAVLDS LRFGRLDDPE TGARNRRILS GVVSGIAHYG NCFGVPTVGG ECIFEPCYDG 

       190        200        210        220        230        240 
NPLVNVFALG VCRKEDVFYA KAAGVGNPVI YVGARTGRDG IHGASMASAE FTEESKQKRP 

       250        260        270        280        290        300 
NVQMGDPFME KLLLEACLEA MQTGAIVGIQ DMGAAGLTCS TCEMGSRGEV GVEIELDRVP 

       310        320        330        340        350        360 
QRATGMTPYE IMLSESQERM LLVADKGRED EVFRVFKKWG LEAVEIGIVT DDGKLRVRHH 

       370        380        390        400        410        420 
GEIVAEIPNR ELADEAPLYD RPHTAPPPAP LAPAPRTSDV PTVQDALPLL LAAPDICSKH 

       430        440        450        460        470        480 
WIWEQYDYQV RTNTLTRPEQ SDASIVRIKE TGTAIAMSLD GNGRYCQLSP REGAILAVAE 

       490        500        510        520        530        540 
SCRNLSVVGA QPVAATNCLN FGNPERPEIM AQLVEAIEGM SDACRFFDTP ITGGNVSLYN 

       550        560        570        580        590        600 
ETLGEGIYPT PVIGIVGLMK TAAPVTVPFQ HAGRSVLLLG GVGTCEETRF GGTQYAKEID 

       610        620        630        640        650        660 
RQLWGLPPAL DLEREKNVQS AIREIVAAGL AESAHDLSDG GLAVALAECS FGNAGIGAQI 

       670        680        690        700        710        720 
DLDSDLRPEW LAFHEGPSRI LISTANPKEV VAIAQRHGVE APVVGVTIES GMEIRQRGNT 

       730        740 
LGSWDIAALR AAYEGALEAH VR

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000473 Genomic DNA. Translation: ABJ86885.1.
RefSeqYP_827170.1. NC_008536.1.

3D structure databases

ProteinModelPortalQ01TY5.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ01TY5.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4425829.
GenomeReviewsGene locus Acid_5944 in contig CP000473_GR.
KEGGsus:Acid_5944.
NMPDRfig|234267.9.peg.5655.
PATRIC32014543. VBICanSol30224_6229.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0046.
HOGENOMHBG311214.
OMAYGNSFGV.
ProtClustDBPRK01213.

Family and domain databases

HAMAPMF_00420. PurL_2.
[Tree]
InterProIPR000728. AIR_synth.
IPR010918. AIR_synth_C.
IPR010074. PRibForGlyAmidine_synth_II.
IPR016188. PurM_N-like.
[Graphical view]
KOK01952.
PfamPF00586. AIRS. 2 hits.
PF02769. AIRS_C. 2 hits.
[Graphical view]
SUPFAMSSF56042. AIR_synth_C. 2 hits.
SSF55326. PurM_N-like. 2 hits.
TIGRFAMsTIGR01736. FGAM_synth_II. 1 hit.
ProtoNetSearch...

Entry information

Entry nameQ01TY5_SOLUE
AccessionPrimary (citable) accession number: Q01TY5
Entry history
Integrated into UniProtKB/TrEMBL: November 14, 2006
Last sequence update: November 14, 2006
Last modified: January 25, 2012
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info