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Protein

UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase

Gene

murG

Organism
Solibacter usitatus (strain Ellin6076)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).UniRule annotation

Catalytic activityi

UDP-N-acetylglucosamine + Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol = UDP + GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol.UniRule annotation

Pathwayi: peptidoglycan biosynthesis

This protein is involved in the pathway peptidoglycan biosynthesis, which is part of Cell wall biogenesis.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway peptidoglycan biosynthesis and in Cell wall biogenesis.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosyltransferase, Transferase
Biological processCell cycle, Cell division, Cell shape, Cell wall biogenesis/degradation, Peptidoglycan synthesis

Enzyme and pathway databases

BioCyciCSOL234267:G1G7G-7522-MONOMER
UniPathwayiUPA00219

Protein family/group databases

CAZyiGT28 Glycosyltransferase Family 28

Names & Taxonomyi

Protein namesi
Recommended name:
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferaseUniRule annotation (EC:2.4.1.227UniRule annotation)
Alternative name(s):
Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferaseUniRule annotation
Gene namesi
Name:murGUniRule annotation
Ordered Locus Names:Acid_7311
OrganismiSolibacter usitatus (strain Ellin6076)
Taxonomic identifieri234267 [NCBI]
Taxonomic lineageiBacteriaAcidobacteriaSolibacteresSolibacteralesSolibacteraceaeCandidatus Solibacter
Proteomesi
  • UP000000671 Componenti: Chromosome

Subcellular locationi

  • Cell inner membrane UniRule annotation; Peripheral membrane protein UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003151701 – 361UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferaseAdd BLAST361

Proteomic databases

PRIDEiQ01Q48

Interactioni

Protein-protein interaction databases

STRINGi234267.Acid_7311

Structurei

3D structure databases

ProteinModelPortaliQ01Q48
SMRiQ01Q48
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyltransferase 28 family. MurG subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105DVQ Bacteria
COG0707 LUCA
HOGENOMiHOG000218321
KOiK02563
OMAiHQTKNAM
OrthoDBiPOG091H02FX

Family and domain databases

CDDicd03785 GT1_MurG, 1 hit
HAMAPiMF_00033 MurG, 1 hit
InterProiView protein in InterPro
IPR006009 GlcNAc_MurG
IPR007235 Glyco_trans_28_C
IPR004276 GlycoTrans_28_N
PfamiView protein in Pfam
PF04101 Glyco_tran_28_C, 1 hit
PF03033 Glyco_transf_28, 1 hit
TIGRFAMsiTIGR01133 murG, 1 hit

Sequencei

Sequence statusi: Complete.

Q01Q48-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTHQQTLPTT AASFLMAGGG TGGHVIPALA VARELRSRGH KVFFVGTQHG
60 70 80 90 100
MEARLVPPEG FEFKTIEIGG LNQVSWNQKF ATLSRLPITT LKCGRSVRDA
110 120 130 140 150
SAVFSMGGYV AGPPVMAALV RRVPVVVMEP NAFPGFTNRV IARLVSRALV
160 170 180 190 200
SFPETAAFFP KGRTEVTGLP VREEFFRIPP KARGDVLQIL ITGGSQGSRT
210 220 230 240 250
LNHAARQSWP LFRNSGYPVR ITHQTGTGSF QEIRDAFAQS GLEGEVVPFI
260 270 280 290 300
ADMPAAFAAA DLIVCRSGAG TVSELAAAGK PSILVPFPFA ADDHQTRNAQ
310 320 330 340 350
SLERAGAARL VRDAEMTGEK FFEVVTSVTG ELSRMGTAAR QFAKPGAAKR
360
AADILEEVAR P
Length:361
Mass (Da):38,584
Last modified:November 14, 2006 - v1
Checksum:i1ED21C97D84E5436
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000473 Genomic DNA Translation: ABJ88222.1
RefSeqiWP_011688938.1, NC_008536.1

Genome annotation databases

EnsemblBacteriaiABJ88222; ABJ88222; Acid_7311
KEGGisus:Acid_7311

Entry informationi

Entry nameiMURG_SOLUE
AccessioniPrimary (citable) accession number: Q01Q48
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: November 14, 2006
Last modified: May 23, 2018
This is version 80 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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