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Protein

Probable L-ascorbate peroxidase 3

Gene

APX3

Organism
Oryza sativa subsp. indica (Rice)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Plays a key role in hydrogen peroxide removal.By similarity

Miscellaneous

Binds one cation per subunit; probably K+, but might also be Ca2+.By similarity

Caution

According to PubMed:15599508, it may be peroxisomal. There is however no experimental evidence to prove this.Curated

Catalytic activityi

2 L-ascorbate + H2O2 + 2 H+ = L-ascorbate + L-dehydroascorbate + 2 H2O.

Cofactori

heme bBy similarityNote: Binds 1 heme b (iron(II)-protoporphyrin IX) group.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sitei37Transition state stabilizerPROSITE-ProRule annotation1
Active sitei41Proton acceptorPROSITE-ProRule annotation1
Metal bindingi161Iron (heme axial ligand)PROSITE-ProRule annotation1
Metal bindingi162Potassium or calciumBy similarity1
Metal bindingi178Potassium or calciumBy similarity1
Metal bindingi185Potassium or calciumBy similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductase, Peroxidase
Biological processHydrogen peroxide
LigandCalcium, Heme, Iron, Metal-binding, Potassium

Names & Taxonomyi

Protein namesi
Recommended name:
Probable L-ascorbate peroxidase 3 (EC:1.11.1.11)
Alternative name(s):
OsAPx03
Gene namesi
Name:APX3
ORF Names:H0515C11.2, OsI_014375
OrganismiOryza sativa subsp. indica (Rice)
Taxonomic identifieri39946 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBOP cladeOryzoideaeOryzeaeOryzinaeOryzaOryza sativa
Proteomesi
  • UP000007015 Componenti: Chromosome 4

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei263 – 283HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003002581 – 291Probable L-ascorbate peroxidase 3Add BLAST291

Proteomic databases

PRIDEiQ01MI9

Expressioni

Gene expression databases

ExpressionAtlasiQ01MI9 differential

Interactioni

Protein-protein interaction databases

STRINGi39946.BGIOSGA015546-PA

Structurei

3D structure databases

ProteinModelPortaliQ01MI9
SMRiQ01MI9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410IF5T Eukaryota
COG0376 LUCA
HOGENOMiHOG000189824
OMAiAHNLGRC
OrthoDBiEOG09360K6Y

Family and domain databases

InterProiView protein in InterPro
IPR010255 Haem_peroxidase
IPR002016 Haem_peroxidase_pln/fun/bac
IPR002207 Peroxidase_I
IPR019794 Peroxidases_AS
IPR019793 Peroxidases_heam-ligand_BS
PfamiView protein in Pfam
PF00141 peroxidase, 1 hit
PRINTSiPR00459 ASPEROXIDASE
PR00458 PEROXIDASE
SUPFAMiSSF48113 SSF48113, 1 hit
PROSITEiView protein in PROSITE
PS00435 PEROXIDASE_1, 1 hit
PS00436 PEROXIDASE_2, 1 hit
PS50873 PEROXIDASE_4, 1 hit

Sequencei

Sequence statusi: Complete.

Q01MI9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSAAPVVDAE YMAEVERARR DLRALIASKS CAPIMLRLAW HDAGTYDKAT
60 70 80 90 100
KTGGPNGSIR FPQEYSHAAN AGIKIAIDLL EPMKQRHPKI TYADLYQLAG
110 120 130 140 150
VVAVEVTGGP TIDYVPGRRD SSDSPEEGRL PDAKKGAAHL REVFYRMGLS
160 170 180 190 200
DKDIVALSGG HTLGKARPER SGFDGAWTKD PLKFDNSYFI ELLKENSEGL
210 220 230 240 250
LKLPTDKALV EDPTFRRYVE LYAKDEDAFF RDYAESHKKL SELGFTPPRS
260 270 280 290
AFIYKSCQKP KSLLMQTAAG VAVAAAVVAW AYLCESNKRL G
Length:291
Mass (Da):32,076
Last modified:November 14, 2006 - v1
Checksum:i9D2E57C3DBC277F6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY382617 mRNA Translation: AAQ88105.1
CR855043 Genomic DNA Translation: CAH66026.1
CM000129 Genomic DNA Translation: EAY93142.1

Genome annotation databases

EnsemblPlantsiBGIOSGA015546-TA; BGIOSGA015546-PA; BGIOSGA015546
GrameneiBGIOSGA015546-TA; BGIOSGA015546-PA; BGIOSGA015546

Similar proteinsi

Entry informationi

Entry nameiAPX3_ORYSI
AccessioniPrimary (citable) accession number: Q01MI9
Secondary accession number(s): A2XQN2, Q6TY83, Q7XWZ7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: November 14, 2006
Last modified: May 23, 2018
This is version 67 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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