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Reviewed, UniProtKB/Swiss-Prot Q01988 (UBP11_CANFA)

Last modified July 28, 2009. Version 56. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Ubiquitin carboxyl-terminal hydrolase 11
    EC=3.1.2.15
Alternative name(s):
    Ubiquitin thioesterase 11
    Ubiquitin-specific-processing protease 11
    Deubiquitinating enzyme 11
Gene names
Name: USP11
OrganismCanis familiaris (Dog)
Taxonomic identifier9615 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCarnivoraCaniformiaCanidaeCanis

Protein attributes

Sequence length445 AA.
Sequence statusFragment.
Sequence processingThe displayed sequence is not processed.
Protein existenceEvidence at transcript level.

General annotation (Comments)

Catalytic activity

Ubiquitin C-terminal thioester + H2O = ubiquitin + a thiol.

Sequence similarities

Belongs to the peptidase C19 family.

Caution

Was originally (Ref.1) thought to be apomucin (also known as mucin core protein; CTM-A).

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain‹1 – 445›445Ubiquitin carboxyl-terminal hydrolase 11
PRO_0000080631

Sites

Active site3621 By similarity
Active site3701 By similarity

Amino acid modifications

Modified residue4301Phosphoserine By similarity
Modified residue4351Phosphoserine By similarity

Experimental info

Non-terminal residue11

Sequences

Sequence LengthMass (Da)Tools
Q01988-1 [UniParc].

Last modified June 1, 1994. Version 1.
Checksum: FE921DD1EEAF7C9E

FASTA44550,892
        10         20         30         40         50         60 
NSARADLCVA LAKHTGMSPE RMMVADVFSH RFYKIYQLEE SLSSILDRDD IFIYEVSGRS 

        70         80         90        100        110        120 
AIGENSREDV VLPIYLRERT PARDYNNSYY GLMLFGHPLL VSVPRDRLSW DALYHILLYR 

       130        140        150        160        170        180 
LSRYVTRPSS DDEDDGDEKD IEDKDNIPKP GHVAGASSQD SGAGSGGAQL WSRRRKPAPV 

       190        200        210        220        230        240 
DNSPGPSHWP QRARRKHLFT LQTVNSNGTS DRSTFNEDTH AQPYIAIDWE PEMKKRYYDE 

       250        260        270        280        290        300 
VEAEGYVKHD CVGYVLKKAP VRLQECIELF TTVETLEKEN PWFCPTCKQH QLATKKLDLW 

       310        320        330        340        350        360 
MLPETLIIHL KRFSYTKFSR EKLDTLVEFP IRDLDFSEFV IKPQNESAPE LYKYDLIAVS 

       370        380        390        400        410        420 
NHYGGLRDGH YTTFACNKDS GQSDYFDDNS VSPVTENQIE SKAAYVLFYQ RQDVARRLQP 

       430        440 
QPSSSDPPAS PACGSPPNSE FMDVN 

« Hide

References

[1]"Molecular cloning of the carboxy terminus of a canine tracheobronchial mucin."
Shankar V., Tan S., Gilmore M.S., Sachdev G.P.
Biochem. Biophys. Res. Commun. 189:958-964(1992) [PubMed: 1282002] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
Tissue: Trachea.

Cross-references

Sequence databases

L03387 mRNA. Translation: AAA30875.1.
PIRI46225. PC1174.
UniGeneCfa.3886

3D structure databases

HSSPHSSP built from PDB template 1NB8 based on UniProtKB Q93009.
ModBaseSearch...

Protein family/group databases

MEROPSC19.014.

Genome annotation databases

EnsemblENSCAFT00000023833; ENSCAFP00000022125; ENSCAFG00000015021; Canis familiaris. [Genome view]

Phylogenomic databases

HOVERGENQ01988.

Enzyme and pathway databases

BRENDA3.1.2.15. 463.

Family and domain databases

InterProIPR018200. Pept_C19ubi-hydrolase_C_CS.
IPR001394. Peptidase_C19.
[Graphical view]
PfamPF00443. UCH. 1 hit.
[Graphical view]
PROSITEPS00972. UCH_2_1. Partial match.
PS00973. UCH_2_2. 1 hit.
PS50235. UCH_2_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameUBP11_CANFA
AccessionPrimary (citable) accession number: Q01988
Entry history
Integrated into UniProtKB/Swiss-Prot: June 1, 1994
Last sequence update: June 1, 1994
Last modified: July 28, 2009
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHPI (Human Proteome Initiative)

Relevant documents

Peptidase families

Classification of peptidase families and list of entries

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents