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Protein

Flagellar biosynthesis protein FlhF

Gene

flhF

Organism
Bacillus subtilis (strain 168)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi182 – 189GTPBy similarity8
Nucleotide bindingi259 – 263GTPBy similarity5
Nucleotide bindingi317 – 320GTPBy similarity4

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Bacterial flagellum biogenesis, Bacterial flagellum protein export, Protein transport, Transport

Keywords - Ligandi

GTP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciBSUB:BSU16400-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Flagellar biosynthesis protein FlhF
Alternative name(s):
Flagella-associated GTP-binding protein
Gene namesi
Name:flhF
Ordered Locus Names:BSU16400
OrganismiBacillus subtilis (strain 168)
Taxonomic identifieri224308 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
Proteomesi
  • UP000001570 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001012201 – 366Flagellar biosynthesis protein FlhFAdd BLAST366

Proteomic databases

PaxDbiQ01960.

Interactioni

Protein-protein interaction databases

DIPiDIP-46493N.
STRINGi224308.Bsubs1_010100009046.

Structurei

Secondary structure

1366
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi111 – 121Combined sources11
Helixi126 – 138Combined sources13
Beta strandi141 – 144Combined sources4
Turni148 – 150Combined sources3
Helixi151 – 160Combined sources10
Helixi166 – 168Combined sources3
Beta strandi175 – 183Combined sources9
Helixi188 – 201Combined sources14
Beta strandi207 – 211Combined sources5
Helixi219 – 227Combined sources9
Turni228 – 231Combined sources4
Beta strandi234 – 236Combined sources3
Helixi240 – 249Combined sources10
Helixi250 – 252Combined sources3
Beta strandi253 – 259Combined sources7
Helixi268 – 277Combined sources10
Beta strandi284 – 291Combined sources8
Helixi296 – 302Combined sources7
Turni303 – 306Combined sources4
Beta strandi307 – 309Combined sources3
Beta strandi313 – 317Combined sources5
Turni319 – 321Combined sources3
Helixi326 – 333Combined sources8
Beta strandi340 – 342Combined sources3
Turni348 – 350Combined sources3
Beta strandi351 – 353Combined sources3
Helixi357 – 364Combined sources8

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2PX0X-ray3.00A/B/C/D/E/F/G/H79-366[»]
2PX3X-ray3.20A79-366[»]
3SYNX-ray3.06A/B/C/D79-366[»]
ProteinModelPortaliQ01960.
SMRiQ01960.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ01960.

Family & Domainsi

Sequence similaritiesi

Belongs to the GTP-binding SRP family.Curated

Phylogenomic databases

eggNOGiENOG4105FZW. Bacteria.
COG1419. LUCA.
HOGENOMiHOG000254735.
InParanoidiQ01960.
KOiK02404.
OMAiWYEVDEY.
PhylomeDBiQ01960.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR020006. FlhF.
IPR027417. P-loop_NTPase.
IPR000897. SRP54_GTPase_dom.
[Graphical view]
PANTHERiPTHR11564:SF3. PTHR11564:SF3. 1 hit.
PfamiPF00448. SRP54. 1 hit.
[Graphical view]
SMARTiSM00962. SRP54. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR03499. FlhF. 1 hit.

Sequencei

Sequence statusi: Complete.

Q01960-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKIKKFTAAS MQEAALLIRK ELGNEAVILN SKKIKKRKWF GLVNKPAVEV
60 70 80 90 100
IAVLDQDFLE KKTPQKAAEP KQTLKTPVSS PKIEERTYPP QIPAQQELGD
110 120 130 140 150
FSAYQSVLPE PLRKAEKLLQ ETGIKESTKT NTLKKLLRFS VEAGGLTEEN
160 170 180 190 200
VVGKLQEILC DMLPSADKWQ EPIHSKYIVL FGSTGAGKTT TLAKLAAISM
210 220 230 240 250
LEKHKKIAFI TTDTYRIAAV EQLKTYAELL QAPLEVCYTK EEFQQAKELF
260 270 280 290 300
SEYDHVFVDT AGRNFKDPQY IDELKETIPF ESSIQSFLVL SATAKYEDMK
310 320 330 340 350
HIVKRFSSVP VNQYIFTKID ETTSLGSVFN ILAESKIGVG FMTNGQNVPE
360
DIQTVSPLGF VRMLCR
Length:366
Mass (Da):41,150
Last modified:June 1, 1994 - v1
Checksum:iE5A3577E49D16F1C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X66445 Genomic DNA. Translation: CAA47062.1.
AL009126 Genomic DNA. Translation: CAB13513.1.
PIRiS25277.
RefSeqiNP_389522.1. NC_000964.3.
WP_003231945.1. NZ_JNCM01000035.1.

Genome annotation databases

EnsemblBacteriaiCAB13513; CAB13513; BSU16400.
GeneIDi940021.
KEGGibsu:BSU16400.
PATRICi18975087. VBIBacSub10457_1735.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X66445 Genomic DNA. Translation: CAA47062.1.
AL009126 Genomic DNA. Translation: CAB13513.1.
PIRiS25277.
RefSeqiNP_389522.1. NC_000964.3.
WP_003231945.1. NZ_JNCM01000035.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2PX0X-ray3.00A/B/C/D/E/F/G/H79-366[»]
2PX3X-ray3.20A79-366[»]
3SYNX-ray3.06A/B/C/D79-366[»]
ProteinModelPortaliQ01960.
SMRiQ01960.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

DIPiDIP-46493N.
STRINGi224308.Bsubs1_010100009046.

Proteomic databases

PaxDbiQ01960.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAB13513; CAB13513; BSU16400.
GeneIDi940021.
KEGGibsu:BSU16400.
PATRICi18975087. VBIBacSub10457_1735.

Phylogenomic databases

eggNOGiENOG4105FZW. Bacteria.
COG1419. LUCA.
HOGENOMiHOG000254735.
InParanoidiQ01960.
KOiK02404.
OMAiWYEVDEY.
PhylomeDBiQ01960.

Enzyme and pathway databases

BioCyciBSUB:BSU16400-MONOMER.

Miscellaneous databases

EvolutionaryTraceiQ01960.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR020006. FlhF.
IPR027417. P-loop_NTPase.
IPR000897. SRP54_GTPase_dom.
[Graphical view]
PANTHERiPTHR11564:SF3. PTHR11564:SF3. 1 hit.
PfamiPF00448. SRP54. 1 hit.
[Graphical view]
SMARTiSM00962. SRP54. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR03499. FlhF. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiFLHF_BACSU
AccessioniPrimary (citable) accession number: Q01960
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 1, 1994
Last sequence update: June 1, 1994
Last modified: November 2, 2016
This is version 115 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Bacillus subtilis
    Bacillus subtilis (strain 168): entries, gene names and cross-references to SubtiList
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.