Q01895 (CYST_SYNY3) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Sulfate transport system permease protein CysT

Gene names

Name:	cysT
Ordered Locus Names:	slr1453

Organism

Synechocystis sp. (strain PCC 6803 / Kazusa) [Reference proteome] [HAMAP]

Taxonomic identifier

1111708 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Cyanobacteria › Oscillatoriophycideae › Chroococcales › Synechocystis › Synechocystis sp. PCC 6803

Protein attributes

Sequence length	286 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Function	Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane By similarity.
Subunit structure	The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP) Probable.
Subcellular location	Cell inner membrane; Multi-pass membrane protein By similarity.
Induction	By sulfur deprivation.
Sequence similarities	Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily. Contains 1 ABC transmembrane type-1 domain.

Ontologies

Keywords
Biological process	Stress response Sulfate transport Transport
Cellular component	Cell inner membrane Cell membrane Membrane
Domain	Transmembrane Transmembrane helix
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	response to stress Inferred from electronic annotation. Source: UniProtKB-KW sulfate transport Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	sulfate transmembrane-transporting ATPase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 286	286	Sulfate transport system permease protein CysT		PRO_0000059992
Regions
	Transmembrane	27 – 47	21	Helical; Potential
	Transmembrane	74 – 94	21	Helical; Potential
	Transmembrane	108 – 128	21	Helical; Potential
	Transmembrane	146 – 166	21	Helical; Potential
	Transmembrane	195 – 215	21	Helical; Potential
	Transmembrane	224 – 244	21	Helical; Potential
	Transmembrane	257 – 276	20	Helical; Potential
	Domain	70 – 273	204	ABC transmembrane type-1

Sequences

	Sequence		Length	Mass (Da)
	Q01895 [UniParc]. Last modified November 1, 1997. Version 2. Checksum: 3C0A1E01F042C587	FASTA	286	31,351
	10 20 30 40 50 60 MTTNLPFSSP SKQLNRFSFW QSISIPWVVT IIYLLLILVL PIAALLVKSA SLGLEGFWQI 70 80 90 100 110 120 ATTPIAISTY NVTFITALAA GLVNGVMGTL VAWVLVRCQF PGKKIVDAMV DLPFALPTSV 130 140 150 160 170 180 AGLVLATLYS QTGWVGRFFA PFGIQIAFSR LGVFVAMVFI SLPFIVRTLQ PVLQELEEEA 190 200 210 220 230 240 EEAAWSLGAT EFQTFWRVIF PPLIPPILTG IALGFSRAVG EYGSVVLIAS NIPFKDLIAP 250 260 270 280 VLVFERLEQY DYPAATVIGA VLLSVSLILL LIINLLQQWG RRYAND

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions." Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S. , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S. DNA Res. 3:109-136(1996) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: PCC 6803 / Kazusa.
[2]	"Nucleotide sequence and homology comparison of two genes of the sulfate transport operon from the cyanobacterium Synechocystis sp. PCC 6803." Kohn C., Schumann J. Plant Mol. Biol. 21:409-412(1993) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-235.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000022 Genomic DNA. Translation: BAA18653.1. X67911 Genomic DNA. Translation: CAA48111.1.
PIR	S76741.
RefSeq	NP_442841.1. NC_000911.1. YP_005652902.1. NC_017277.1. YP_007452717.1. NC_020286.1.
3D structure databases
ProteinModelPortal	Q01895.
ModBase	Search...
Protein-protein interaction databases
STRING	1148.slr1453.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	BAA18653; BAA18653; BAA18653.
GeneID	12255261. 14618402. 953274.
KEGG	syn:slr1453. syy:SYNGTS_2949.
PATRIC	23843460. VBISynSp132158_3265.
Phylogenomic databases
eggNOG	COG0555.
HOGENOM	HOG000263698.
KO	K02046.
OMA	PLVIMSK.
ProtClustDB	CLSK893740.
Family and domain databases
InterPro	IPR000515. BPD_transp. IPR011865. CysT_permease. IPR005667. Sulph_transpt2. [Graphical view]
Pfam	PF00528. BPD_transp_1. 1 hit. [Graphical view]
TIGRFAMs	TIGR00969. 3a0106s02. 1 hit. TIGR02139. permease_CysT. 1 hit.
PROSITE	PS50928. ABC_TM1. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

CYST_SYNY3

Accession

Primary (citable) accession number: Q01895

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 1, 1993
Last sequence update:	November 1, 1997
Last modified:	May 1, 2013
This is version 94 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program