Q01855 (RS15_YEAST) Reviewed, UniProtKB/Swiss-Prot
Last modified
December 14, 2011.
Version 105.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: 40S ribosomal protein S15 Alternative name(s): RIG protein RP52 S21 YS21 | ||||||
| Gene names |
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| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | ||||||
| Taxonomic identifier | 559292 [NCBI] | ||||||
| Taxonomic lineage | Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces |
Protein attributes
| Sequence length | 142 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is further processed into a mature form. |
| Protein existence | Evidence at protein level |
General annotation (Comments)
| Function | Involved in the nuclear export of the small ribosomal subunit. Has a role in the late stage of the assembly of pre-40S particles within the nucleus and controls their export to the cytoplasm. Ref.7 |
| Subunit structure | Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains 32 different proteins (encoded by 56 genes) and 1 molecule of RNA (18S). The 60S subunit contains 46 different proteins (encoded by 81 genes) and 3 molecules of RNA (25S, 5.8S and 5S). Ref.5 |
| Subcellular location | Cytoplasm By similarity. |
| Sequence similarities | Belongs to the ribosomal protein S19P family. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Ribosome biogenesis |
| Cellular component | Cytoplasm |
| Molecular function | Ribonucleoprotein Ribosomal protein |
| PTM | Acetylation Phosphoprotein |
| Technical term | 3D-structure Complete proteome Reference proteome |
| Gene Ontology (GO) | |
| Biological process | cytoplasmic translation Non-traceable author statement Ref.5. Source: SGD rRNA export from nucleusInferred from mutant phenotype Ref.7. Source: SGD |
| Cellular component | cytosolic small ribosomal subunit Non-traceable author statement Ref.5. Source: SGD |
| Molecular function | RNA binding Inferred from electronic annotation. Source: InterPro structural constituent of ribosomeNon-traceable author statement Ref.5. Source: SGD |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Initiator methionine | 1 | 1 | Removed Ref.6 | ||||||
| Chain | 2 – 142 | 141 | 40S ribosomal protein S15 | PRO_0000130051 | |||||
Amino acid modifications | |||||||||
| Modified residue | 2 | 1 | N-acetylserine Ref.6 | ||||||
| Modified residue | 16 | 1 | Phosphoserine Ref.8 | ||||||
| Modified residue | 124 | 1 | Phosphothreonine Ref.9 | ||||||
Sequences
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References
| « Hide 'large scale' references | |
| [1] | "Structural determination of Saccharomyces cerevisiae rig gene and identification of its product as ribosomal protein S21." Takasawa S., Tohgo A., Unno M., Yonekura H., Okamoto H. FEBS Lett. 307:318-323(1992) [PubMed: 1644188] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA]. |
| [2] | "The nucleotide sequence of Saccharomyces cerevisiae chromosome XV." Dujon B., Albermann K., Aldea M., Alexandraki D., Ansorge W., Arino J., Benes V., Bohn C., Bolotin-Fukuhara M., Bordonne R., Boyer J., Camasses A., Casamayor A., Casas C., Cheret G., Cziepluch C., Daignan-Fornier B., Dang V.-D. Kleine K.Nature 387:98-102(1997) [PubMed: 9169874] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 96604 / S288c / FY1679. |
| [3] | Saccharomyces Genome Database Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: ATCC 204508 / S288c. |
| [4] | "Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae." Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F., Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J., Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J. LaBaer J.Genome Res. 17:536-543(2007) [PubMed: 17322287] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 204508 / S288c. |
| [5] | "The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae." Planta R.J., Mager W.H. Yeast 14:471-477(1998) [PubMed: 9559554] [Abstract] Cited for: NOMENCLATURE, SUBUNIT. |
| [6] | "The action of N-terminal acetyltransferases on yeast ribosomal proteins." Arnold R.J., Polevoda B., Reilly J.P., Sherman F. J. Biol. Chem. 274:37035-37040(1999) [PubMed: 10601260] [Abstract] Cited for: CLEAVAGE OF INITIATOR METHIONINE, ACETYLATION AT SER-2 BY NATA. |
| [7] | "The ribosomal protein Rps15p is required for nuclear exit of the 40S subunit precursors in yeast." Leger-Silvestre I., Milkereit P., Ferreira-Cerca S., Saveanu C., Rousselle J.-C., Choesmel V., Guinefoleau C., Gas N., Gleizes P.-E. EMBO J. 23:2336-2347(2004) [PubMed: 15167894] [Abstract] Cited for: FUNCTION. |
| [8] | "Analysis of phosphorylation sites on proteins from Saccharomyces cerevisiae by electron transfer dissociation (ETD) mass spectrometry." Chi A., Huttenhower C., Geer L.Y., Coon J.J., Syka J.E.P., Bai D.L., Shabanowitz J., Burke D.J., Troyanskaya O.G., Hunt D.F. Proc. Natl. Acad. Sci. U.S.A. 104:2193-2198(2007) [PubMed: 17287358] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-16, MASS SPECTROMETRY. |
| [9] | "A multidimensional chromatography technology for in-depth phosphoproteome analysis." Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H. Mol. Cell. Proteomics 7:1389-1396(2008) [PubMed: 18407956] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-124, MASS SPECTROMETRY. |
| [10] | "Structure of the 80S ribosome from Saccharomyces cerevisiae -- tRNA-ribosome and subunit-subunit interactions." Spahn C.M.T., Beckmann R., Eswar N., Penczek P.A., Sali A., Blobel G., Frank J. Cell 107:373-386(2001) [PubMed: 11701127] [Abstract] Cited for: 3D-STRUCTURE MODELING OF 47-126, ELECTRON MICROSCOPY. |
| [11] | "Domain movements of elongation factor eEF2 and the eukaryotic 80S ribosome facilitate tRNA translocation." Spahn C.M.T., Gomez-Lorenzo M.G., Grassucci R.A., Joergensen R., Andersen G.R., Beckmann R., Penczek P.A., Ballesta J.P.G., Frank J. EMBO J. 23:1008-1019(2004) [PubMed: 14976550] [Abstract] Cited for: 3D-STRUCTURE MODELING OF 47-126, ELECTRON MICROSCOPY. |
| + | Additional computationally mapped references. |
Cross-references
Sequence databases | |||||||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| EMBL GenBank DDBJ | D11386 mRNA. Translation: BAA01982.1. D11387 Genomic DNA. Translation: BAA01983.1. Z74782 Genomic DNA. Translation: CAA99042.1. AY558426 Genomic DNA. Translation: AAS56752.1. BK006948 Genomic DNA. Translation: DAA10742.1. | ||||||||||||||||||||||||||||||||||||
| PIR | S24053. | ||||||||||||||||||||||||||||||||||||
| RefSeq | NP_014602.1. NM_001183294.1. | ||||||||||||||||||||||||||||||||||||
3D structure databases | |||||||||||||||||||||||||||||||||||||
| PDBe RCSB PDB PDBj |
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| ProteinModelPortal | Q01855. | ||||||||||||||||||||||||||||||||||||
| SMR | Q01855. Positions 47-117. | ||||||||||||||||||||||||||||||||||||
| ModBase | Search... | ||||||||||||||||||||||||||||||||||||
Protein-protein interaction databases | |||||||||||||||||||||||||||||||||||||
| IntAct | Q01855. 3 interactions. | ||||||||||||||||||||||||||||||||||||
| STRING | Q01855. | ||||||||||||||||||||||||||||||||||||
Proteomic databases | |||||||||||||||||||||||||||||||||||||
| PeptideAtlas | Q01855. | ||||||||||||||||||||||||||||||||||||
Protocols and materials databases | |||||||||||||||||||||||||||||||||||||
| StructuralBiologyKnowledgebase | Search... | ||||||||||||||||||||||||||||||||||||
Genome annotation databases | |||||||||||||||||||||||||||||||||||||
| EnsemblFungi | YOL040C; YOL040C; YOL040C. | ||||||||||||||||||||||||||||||||||||
| GeneID | 854117. | ||||||||||||||||||||||||||||||||||||
| KEGG | sce:YOL040C. | ||||||||||||||||||||||||||||||||||||
| NMPDR | fig|4932.3.peg.5694. | ||||||||||||||||||||||||||||||||||||
Organism-specific databases | |||||||||||||||||||||||||||||||||||||
| CYGD | YOL040c. | ||||||||||||||||||||||||||||||||||||
| SGD | S000005400. RPS15. | ||||||||||||||||||||||||||||||||||||
Phylogenomic databases | |||||||||||||||||||||||||||||||||||||
| eggNOG | fuNOG09065. | ||||||||||||||||||||||||||||||||||||
| GeneTree | EFGT00050000006600. | ||||||||||||||||||||||||||||||||||||
| HOGENOM | HBG307515. | ||||||||||||||||||||||||||||||||||||
| OMA | THCRDMI. | ||||||||||||||||||||||||||||||||||||
| OrthoDB | EOG4HHSBV. | ||||||||||||||||||||||||||||||||||||
Gene expression databases | |||||||||||||||||||||||||||||||||||||
| ArrayExpress | Q01855. | ||||||||||||||||||||||||||||||||||||
| Genevestigator | Q01855. | ||||||||||||||||||||||||||||||||||||
| GermOnline | YOL040C. Saccharomyces cerevisiae. | ||||||||||||||||||||||||||||||||||||
Family and domain databases | |||||||||||||||||||||||||||||||||||||
| InterPro | IPR002222. Ribosomal_S19. IPR020934. Ribosomal_S19_CS. IPR023575. Ribosomal_S19_SF. IPR005713. Ribosomal_S19A/S15e. [Graphical view] | ||||||||||||||||||||||||||||||||||||
| Gene3D | G3DSA:3.30.860.10. Ribosomal_S19. 1 hit. | ||||||||||||||||||||||||||||||||||||
| KO | K02958. | ||||||||||||||||||||||||||||||||||||
| PANTHER | PTHR11880. Ribosomal_S19. 1 hit. | ||||||||||||||||||||||||||||||||||||
| Pfam | PF00203. Ribosomal_S19. 1 hit. [Graphical view] | ||||||||||||||||||||||||||||||||||||
| PIRSF | PIRSF002144. Ribosomal_S19. 1 hit. | ||||||||||||||||||||||||||||||||||||
| PRINTS | PR00975. RIBOSOMALS19. | ||||||||||||||||||||||||||||||||||||
| SUPFAM | SSF54570. Ribosomal_S19. 1 hit. | ||||||||||||||||||||||||||||||||||||
| TIGRFAMs | TIGR01025. RpsS_arch. 1 hit. | ||||||||||||||||||||||||||||||||||||
| PROSITE | PS00323. RIBOSOMAL_S19. 1 hit. [Graphical view] | ||||||||||||||||||||||||||||||||||||
| ProtoNet | Search... | ||||||||||||||||||||||||||||||||||||
Other | |||||||||||||||||||||||||||||||||||||
| NextBio | 975816. | ||||||||||||||||||||||||||||||||||||
Entry information
| Entry name | RS15_YEAST | ||||||||
| Accession | Primary (citable) accession number: Q01855 Secondary accession number(s): D6W226 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Fungal Protein Annotation Program | ||||||||
Relevant documents
| Yeast Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD |
| Ribosomal proteins Ribosomal proteins families and list of entries |
| PDB cross-references Index of Protein Data Bank (PDB) cross-references |
| SIMILARITY comments Index of protein domains and families |

Clusters with