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Q01667 (CAB6_ARATH) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 104. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Alt products·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Chlorophyll a-b binding protein 6, chloroplastic
Alternative name(s):
LHCI-730
LHCII type III CAB-6
Light-harvesting complex protein Lhca1
Gene names
Name:LHCA1
Synonyms:CAB6
Ordered Locus Names:At3g54890
ORF Names:F28P10.130
OrganismArabidopsis thaliana (Mouse-ear cress) [Reference proteome]
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis

Protein attributes

Sequence length241 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated.

Cofactor

Binds at least 14 chlorophylls (8 Chl-a and 6 Chl-b) and carotenoids such as lutein and neoxanthin By similarity.

Subunit structure

The LHC complex consists of chlorophyll a-b binding proteins. Heterodimer with LHCA4.

Subcellular location

Plastidchloroplast thylakoid membrane; Multi-pass membrane protein.

Domain

The N-terminus of the protein extends into the stroma where it is involved with adhesion of granal membranes and post-translational modifications; both are believed to mediate the distribution of excitation energy between photosystems I and II.

Post-translational modification

Photoregulated by reversible phosphorylation of its threonine residues By similarity.

Sequence similarities

Belongs to the light-harvesting chlorophyll a/b-binding (LHC) protein family.

Ontologies

Keywords
   Biological processPhotosynthesis
   Cellular componentChloroplast
Membrane
Photosystem I
Photosystem II
Plastid
Thylakoid
   Coding sequence diversityAlternative splicing
   DomainTransit peptide
Transmembrane
Transmembrane helix
   LigandChlorophyll
Chromophore
Magnesium
Metal-binding
   PTMPhosphoprotein
   Technical term3D-structure
Complete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processphotosynthesis, light harvesting in photosystem I

Inferred from mutant phenotype PubMed 16098971. Source: TAIR

protein-chromophore linkage

Inferred from electronic annotation. Source: UniProtKB-KW

response to blue light

Inferred from expression pattern PubMed 18820083. Source: TAIR

response to far red light

Inferred from expression pattern PubMed 18820083. Source: TAIR

response to red light

Inferred from expression pattern PubMed 18820083. Source: TAIR

   Cellular_componentchloroplast

Inferred from direct assay PubMed 15028209PubMed 18431481. Source: TAIR

chloroplast envelope

Inferred from direct assay PubMed 12766230. Source: TAIR

chloroplast thylakoid

Inferred from direct assay PubMed 20061580. Source: TAIR

chloroplast thylakoid membrane

Inferred from direct assay PubMed 14729914PubMed 15322131. Source: TAIR

integral component of membrane

Inferred from electronic annotation. Source: UniProtKB-KW

membrane

Inferred from direct assay PubMed 17432890. Source: TAIR

photosystem I

Inferred from electronic annotation. Source: UniProtKB-KW

photosystem II

Inferred from electronic annotation. Source: UniProtKB-KW

plastoglobule

Inferred from direct assay PubMed 16414959. Source: TAIR

thylakoid

Inferred from direct assay PubMed 18633119. Source: TAIR

   Molecular_functionchlorophyll binding

Inferred from electronic annotation. Source: UniProtKB-KW

metal ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Alternative products

This entry describes 1 isoform produced by alternative splicing. [Select]

Note: A number of isoforms are produced. According to EST sequences.
Isoform 1 (identifier: Q01667-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Transit peptide1 – 3535Chloroplast Potential
Chain36 – 241206Chlorophyll a-b binding protein 6, chloroplastic
PRO_0000401362

Regions

Transmembrane93 – 11321Helical; Potential
Transmembrane132 – 15221Helical; Potential
Transmembrane197 – 21721Helical; Potential

Sites

Metal binding481Magnesium (chlorophyll-b 1 axial ligand); via carbonyl oxygen By similarity
Metal binding871Magnesium (chlorophyll-a 1 axial ligand) By similarity
Metal binding901Magnesium (chlorophyll-a 2 axial ligand) By similarity
Metal binding1331Magnesium (chlorophyll-b 2 axial ligand); via carbonyl oxygen By similarity
Metal binding1531Magnesium (chlorophyll-b 3 axial ligand) By similarity
Metal binding1911Magnesium (chlorophyll-a 3 axial ligand) By similarity
Metal binding1941Magnesium (chlorophyll-a 4 axial ligand) By similarity
Metal binding2081Magnesium (chlorophyll-a 5 axial ligand) By similarity
Metal binding2241Magnesium (chlorophyll-a 6 axial ligand) By similarity
Binding site681Chlorophyll-a 1; via amide nitrogen By similarity
Binding site921Chlorophyll-b 2 By similarity
Binding site1291Chlorophyll-a 3; via amide nitrogen By similarity
Binding site1561Chlorophyll-b 4 By similarity
Binding site1901Chlorophyll-a 5 By similarity
Binding site1961Chlorophyll-a 1 By similarity

Experimental info

Sequence conflict111I → K in AAG40043. Ref.4
Sequence conflict431R → K in AAG40043. Ref.4

Secondary structure

................................... 241
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
Isoform 1 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: 2F5EE06B55A979CE

FASTA24125,996
        10         20         30         40         50         60 
MASNSLMSCG IAAVYPSLLS SSKSKFVSAG VPLPNAGNVG RIRMAAHWMP GEPRPAYLDG 

        70         80         90        100        110        120 
SAPGDFGFDP LGLGEVPANL ERYKESELIH CRWAMLAVPG ILVPEALGYG NWVKAQEWAA 

       130        140        150        160        170        180 
LPGGQATYLG NPVPWGTLPT ILAIEFLAIA FVEHQRSMEK DPEKKKYPGG AFDPLGYSKD 

       190        200        210        220        230        240 
PKKLEELKVK EIKNGRLALL AFVGFCVQQS AYPGTGPLEN LATHLADPWH NNIGDIVIPF 


N 

« Hide

References

« Hide 'large scale' references
[1]"Identification of a single-copy gene encoding a type I chlorophyll a/b-binding polypeptide of photosystem I in Arabidopsis thaliana."
Jensen P.E., Kristensen M., Lehmbeck J., Hoff T., Stummann B.M., Henningsen K.W.
Physiol. Plantarum 84:561-567(1992)
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA].
Strain: cv. Columbia.
[2]"Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana."
Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B., Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M., Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V., Choisne N., Artiguenave F. expand/collapse author list , Robert C., Brottier P., Wincker P., Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H., Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H., Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A., Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H., Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J., Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B., Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D., de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E., Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G., Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X., Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M., Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B., Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J., Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C., Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y., Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K., Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.
Nature 408:820-822(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.
[3]The Arabidopsis Information Resource (TAIR)
Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: cv. Columbia.
[4]"Empirical analysis of transcriptional activity in the Arabidopsis genome."
Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G. expand/collapse author list , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: cv. Columbia.
[5]"Analysis of multiple occurrences of alternative splicing events in Arabidopsis thaliana using novel sequenced full-length cDNAs."
Iida K., Fukami-Kobayashi K., Toyoda A., Sakaki Y., Kobayashi M., Seki M., Shinozaki K.
DNA Res. 16:155-164(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 83-241.
Strain: cv. Columbia.
[6]"The structure of a plant photosystem I supercomplex at 3.4 A resolution."
Amunts A., Drory O., Nelson N.
Nature 447:58-63(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (3.4 ANGSTROMS) OF 49-235.
[7]"Structure determination and improved model of plant photosystem I."
Amunts A., Toporik H., Borovikova A., Nelson N.
J. Biol. Chem. 285:3478-3486(2010) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (3.3 ANGSTROMS).
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
M85150 Genomic DNA. Translation: AAA32759.1.
X56062 mRNA. Translation: CAA39534.1.
AL049655 Genomic DNA. Translation: CAB41095.1.
CP002686 Genomic DNA. Translation: AEE79306.1.
AF324692 mRNA. Translation: AAG40043.2.
AF325016 mRNA. Translation: AAG40368.1.
AF326866 mRNA. Translation: AAG41448.1.
AF339688 mRNA. Translation: AAK00370.1.
AF361847 mRNA. Translation: AAK32859.1.
AY070473 mRNA. Translation: AAL49939.1.
AY094437 mRNA. Translation: AAM19809.1.
BT000852 mRNA. Translation: AAN38689.1.
AK317555 mRNA. Translation: BAH20219.1.
PIRS25435.
RefSeqNP_191049.1. NM_115346.3.
UniGeneAt.23982.
At.67867.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
2O01X-ray3.40149-235[»]
2WSCX-ray3.3011-241[»]
2WSEX-ray3.4911-241[»]
2WSFX-ray3.4811-241[»]
ProteinModelPortalQ01667.
SMRQ01667. Positions 61-230.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

DIPDIP-59003N.
STRING3702.AT3G54890.1-P.

Proteomic databases

PaxDbQ01667.
PRIDEQ01667.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsAT3G54890.1; AT3G54890.1; AT3G54890. [Q01667-1]
GeneID824654.
KEGGath:AT3G54890.

Organism-specific databases

TAIRAT3G54890.

Phylogenomic databases

eggNOGNOG263751.
HOGENOMHOG000238033.
InParanoidQ01667.
KOK08907.
OMAMASNSLM.
PhylomeDBQ01667.
ProtClustDBPLN00099.

Gene expression databases

ArrayExpressQ01667.
GenevestigatorQ01667.

Family and domain databases

Gene3D1.10.3460.10. 1 hit.
InterProIPR001344. Chloro_AB-bd_pln.
IPR022796. Chloroa_b-bind.
IPR023329. Chlorophyll_a/b-bd_dom.
[Graphical view]
PANTHERPTHR21649. PTHR21649. 1 hit.
PfamPF00504. Chloroa_b-bind. 1 hit.
[Graphical view]
SUPFAMSSF103511. SSF103511. 1 hit.
ProtoNetSearch...

Other

EvolutionaryTraceQ01667.

Entry information

Entry nameCAB6_ARATH
AccessionPrimary (citable) accession number: Q01667
Secondary accession number(s): B9DHK2, Q9C5R7
Entry history
Integrated into UniProtKB/Swiss-Prot: November 30, 2010
Last sequence update: November 1, 1996
Last modified: April 16, 2014
This is version 104 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names