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Q01667

- CAB6_ARATH

UniProt

Q01667 - CAB6_ARATH

Protein

Chlorophyll a-b binding protein 6, chloroplastic

Gene

LHCA1

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 106 (01 Oct 2014)
      Sequence version 1 (01 Nov 1996)
      Previous versions | rss
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    Functioni

    The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated.

    Cofactori

    Binds at least 14 chlorophylls (8 Chl-a and 6 Chl-b) and carotenoids such as lutein and neoxanthin.By similarity

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi48 – 481Magnesium (chlorophyll-b 1 axial ligand); via carbonyl oxygenBy similarity
    Binding sitei68 – 681Chlorophyll-a 1; via amide nitrogenBy similarity
    Metal bindingi87 – 871Magnesium (chlorophyll-a 1 axial ligand)By similarity
    Metal bindingi90 – 901Magnesium (chlorophyll-a 2 axial ligand)By similarity
    Binding sitei92 – 921Chlorophyll-b 2By similarity
    Binding sitei129 – 1291Chlorophyll-a 3; via amide nitrogenBy similarity
    Metal bindingi133 – 1331Magnesium (chlorophyll-b 2 axial ligand); via carbonyl oxygenBy similarity
    Metal bindingi153 – 1531Magnesium (chlorophyll-b 3 axial ligand)By similarity
    Binding sitei156 – 1561Chlorophyll-b 4By similarity
    Binding sitei190 – 1901Chlorophyll-a 5By similarity
    Metal bindingi191 – 1911Magnesium (chlorophyll-a 3 axial ligand)By similarity
    Metal bindingi194 – 1941Magnesium (chlorophyll-a 4 axial ligand)By similarity
    Binding sitei196 – 1961Chlorophyll-a 1By similarity
    Metal bindingi208 – 2081Magnesium (chlorophyll-a 5 axial ligand)By similarity
    Metal bindingi224 – 2241Magnesium (chlorophyll-a 6 axial ligand)By similarity

    GO - Molecular functioni

    1. chlorophyll binding Source: UniProtKB-KW
    2. metal ion binding Source: UniProtKB-KW

    GO - Biological processi

    1. photosynthesis, light harvesting in photosystem I Source: TAIR
    2. protein-chromophore linkage Source: UniProtKB-KW
    3. response to blue light Source: TAIR
    4. response to far red light Source: TAIR
    5. response to red light Source: TAIR

    Keywords - Biological processi

    Photosynthesis

    Keywords - Ligandi

    Chlorophyll, Chromophore, Magnesium, Metal-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Chlorophyll a-b binding protein 6, chloroplastic
    Alternative name(s):
    LHCI-730
    LHCII type III CAB-6
    Light-harvesting complex protein Lhca1
    Gene namesi
    Name:LHCA1
    Synonyms:CAB6
    Ordered Locus Names:At3g54890
    ORF Names:F28P10.130
    OrganismiArabidopsis thaliana (Mouse-ear cress)
    Taxonomic identifieri3702 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
    ProteomesiUP000006548: Chromosome 3

    Organism-specific databases

    TAIRiAT3G54890.

    Subcellular locationi

    GO - Cellular componenti

    1. chloroplast Source: TAIR
    2. chloroplast envelope Source: TAIR
    3. chloroplast thylakoid Source: TAIR
    4. chloroplast thylakoid membrane Source: TAIR
    5. integral component of membrane Source: UniProtKB-KW
    6. membrane Source: TAIR
    7. photosystem I Source: UniProtKB-KW
    8. photosystem II Source: UniProtKB-KW
    9. plastoglobule Source: TAIR
    10. thylakoid Source: TAIR

    Keywords - Cellular componenti

    Chloroplast, Membrane, Photosystem I, Photosystem II, Plastid, Thylakoid

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transit peptidei1 – 3535ChloroplastSequence AnalysisAdd
    BLAST
    Chaini36 – 241206Chlorophyll a-b binding protein 6, chloroplasticPRO_0000401362Add
    BLAST

    Post-translational modificationi

    Photoregulated by reversible phosphorylation of its threonine residues.By similarity

    Keywords - PTMi

    Phosphoprotein

    Proteomic databases

    PaxDbiQ01667.
    PRIDEiQ01667.

    Expressioni

    Gene expression databases

    ArrayExpressiQ01667.
    GenevestigatoriQ01667.

    Interactioni

    Subunit structurei

    The LHC complex consists of chlorophyll a-b binding proteins. Heterodimer with LHCA4.

    Protein-protein interaction databases

    DIPiDIP-59003N.
    STRINGi3702.AT3G54890.1-P.

    Structurei

    Secondary structure

    1
    241
    Legend: HelixTurnBeta strand
    Show more details
    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Beta strandi51 – 533
    Beta strandi67 – 693
    Turni71 – 788
    Helixi79 – 824
    Helixi84 – 9411
    Turni95 – 973
    Helixi98 – 1003
    Beta strandi101 – 1033
    Beta strandi119 – 1213
    Beta strandi129 – 1313
    Beta strandi133 – 1375
    Helixi138 – 14811
    Helixi150 – 1567
    Beta strandi160 – 1634
    Beta strandi165 – 1673
    Beta strandi174 – 1763
    Beta strandi180 – 1834
    Helixi191 – 20313
    Helixi205 – 2095
    Beta strandi210 – 2123

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    2O01X-ray3.40149-235[»]
    2WSCX-ray3.3011-241[»]
    2WSEX-ray3.4911-241[»]
    2WSFX-ray3.4811-241[»]
    ProteinModelPortaliQ01667.
    SMRiQ01667. Positions 61-230.
    ModBaseiSearch...
    MobiDBiSearch...

    Miscellaneous databases

    EvolutionaryTraceiQ01667.

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei93 – 11321HelicalSequence AnalysisAdd
    BLAST
    Transmembranei132 – 15221HelicalSequence AnalysisAdd
    BLAST
    Transmembranei197 – 21721HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Domaini

    The N-terminus of the protein extends into the stroma where it is involved with adhesion of granal membranes and post-translational modifications; both are believed to mediate the distribution of excitation energy between photosystems I and II.

    Sequence similaritiesi

    Keywords - Domaini

    Transit peptide, Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiNOG263751.
    HOGENOMiHOG000238033.
    InParanoidiQ01667.
    KOiK08907.
    OMAiMASNSLM.
    PhylomeDBiQ01667.

    Family and domain databases

    Gene3Di1.10.3460.10. 1 hit.
    InterProiIPR001344. Chloro_AB-bd_pln.
    IPR022796. Chloroa_b-bind.
    IPR023329. Chlorophyll_a/b-bd_dom.
    [Graphical view]
    PANTHERiPTHR21649. PTHR21649. 1 hit.
    PfamiPF00504. Chloroa_b-bind. 1 hit.
    [Graphical view]
    SUPFAMiSSF103511. SSF103511. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    This entry describes 1 isoform i produced by alternative splicing. Align

    Note: A number of isoforms are produced. According to EST sequences.

    Isoform 1 (identifier: Q01667-1) [UniParc]FASTAAdd to Basket

    This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

    « Hide

    MASNSLMSCG IAAVYPSLLS SSKSKFVSAG VPLPNAGNVG RIRMAAHWMP    50
    GEPRPAYLDG SAPGDFGFDP LGLGEVPANL ERYKESELIH CRWAMLAVPG 100
    ILVPEALGYG NWVKAQEWAA LPGGQATYLG NPVPWGTLPT ILAIEFLAIA 150
    FVEHQRSMEK DPEKKKYPGG AFDPLGYSKD PKKLEELKVK EIKNGRLALL 200
    AFVGFCVQQS AYPGTGPLEN LATHLADPWH NNIGDIVIPF N 241
    Length:241
    Mass (Da):25,996
    Last modified:November 1, 1996 - v1
    Checksum:i2F5EE06B55A979CE
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti11 – 111I → K in AAG40043. (PubMed:14593172)Curated
    Sequence conflicti43 – 431R → K in AAG40043. (PubMed:14593172)Curated

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    M85150 Genomic DNA. Translation: AAA32759.1.
    X56062 mRNA. Translation: CAA39534.1.
    AL049655 Genomic DNA. Translation: CAB41095.1.
    CP002686 Genomic DNA. Translation: AEE79306.1.
    AF324692 mRNA. Translation: AAG40043.2.
    AF325016 mRNA. Translation: AAG40368.1.
    AF326866 mRNA. Translation: AAG41448.1.
    AF339688 mRNA. Translation: AAK00370.1.
    AF361847 mRNA. Translation: AAK32859.1.
    AY070473 mRNA. Translation: AAL49939.1.
    AY094437 mRNA. Translation: AAM19809.1.
    BT000852 mRNA. Translation: AAN38689.1.
    AK317555 mRNA. Translation: BAH20219.1.
    PIRiS25435.
    RefSeqiNP_191049.1. NM_115346.3. [Q01667-1]
    UniGeneiAt.23982.
    At.67867.

    Genome annotation databases

    EnsemblPlantsiAT3G54890.1; AT3G54890.1; AT3G54890. [Q01667-1]
    GeneIDi824654.
    KEGGiath:AT3G54890.

    Keywords - Coding sequence diversityi

    Alternative splicing

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    M85150 Genomic DNA. Translation: AAA32759.1 .
    X56062 mRNA. Translation: CAA39534.1 .
    AL049655 Genomic DNA. Translation: CAB41095.1 .
    CP002686 Genomic DNA. Translation: AEE79306.1 .
    AF324692 mRNA. Translation: AAG40043.2 .
    AF325016 mRNA. Translation: AAG40368.1 .
    AF326866 mRNA. Translation: AAG41448.1 .
    AF339688 mRNA. Translation: AAK00370.1 .
    AF361847 mRNA. Translation: AAK32859.1 .
    AY070473 mRNA. Translation: AAL49939.1 .
    AY094437 mRNA. Translation: AAM19809.1 .
    BT000852 mRNA. Translation: AAN38689.1 .
    AK317555 mRNA. Translation: BAH20219.1 .
    PIRi S25435.
    RefSeqi NP_191049.1. NM_115346.3. [Q01667-1 ]
    UniGenei At.23982.
    At.67867.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    2O01 X-ray 3.40 1 49-235 [» ]
    2WSC X-ray 3.30 1 1-241 [» ]
    2WSE X-ray 3.49 1 1-241 [» ]
    2WSF X-ray 3.48 1 1-241 [» ]
    ProteinModelPortali Q01667.
    SMRi Q01667. Positions 61-230.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    DIPi DIP-59003N.
    STRINGi 3702.AT3G54890.1-P.

    Proteomic databases

    PaxDbi Q01667.
    PRIDEi Q01667.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblPlantsi AT3G54890.1 ; AT3G54890.1 ; AT3G54890 . [Q01667-1 ]
    GeneIDi 824654.
    KEGGi ath:AT3G54890.

    Organism-specific databases

    TAIRi AT3G54890.

    Phylogenomic databases

    eggNOGi NOG263751.
    HOGENOMi HOG000238033.
    InParanoidi Q01667.
    KOi K08907.
    OMAi MASNSLM.
    PhylomeDBi Q01667.

    Miscellaneous databases

    EvolutionaryTracei Q01667.

    Gene expression databases

    ArrayExpressi Q01667.
    Genevestigatori Q01667.

    Family and domain databases

    Gene3Di 1.10.3460.10. 1 hit.
    InterProi IPR001344. Chloro_AB-bd_pln.
    IPR022796. Chloroa_b-bind.
    IPR023329. Chlorophyll_a/b-bd_dom.
    [Graphical view ]
    PANTHERi PTHR21649. PTHR21649. 1 hit.
    Pfami PF00504. Chloroa_b-bind. 1 hit.
    [Graphical view ]
    SUPFAMi SSF103511. SSF103511. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Identification of a single-copy gene encoding a type I chlorophyll a/b-binding polypeptide of photosystem I in Arabidopsis thaliana."
      Jensen P.E., Kristensen M., Lehmbeck J., Hoff T., Stummann B.M., Henningsen K.W.
      Physiol. Plantarum 84:561-567(1992)
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA].
      Strain: cv. Columbia.
    2. "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana."
      Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B., Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M., Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V., Choisne N., Artiguenave F.
      , Robert C., Brottier P., Wincker P., Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H., Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H., Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A., Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H., Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J., Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B., Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D., de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E., Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G., Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X., Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M., Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B., Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J., Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C., Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y., Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K., Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.
      Nature 408:820-822(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: cv. Columbia.
    3. The Arabidopsis Information Resource (TAIR)
      Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
      Cited for: GENOME REANNOTATION.
      Strain: cv. Columbia.
    4. "Empirical analysis of transcriptional activity in the Arabidopsis genome."
      Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G.
      , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
      Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: cv. Columbia.
    5. "Analysis of multiple occurrences of alternative splicing events in Arabidopsis thaliana using novel sequenced full-length cDNAs."
      Iida K., Fukami-Kobayashi K., Toyoda A., Sakaki Y., Kobayashi M., Seki M., Shinozaki K.
      DNA Res. 16:155-164(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 83-241.
      Strain: cv. Columbia.
    6. "The structure of a plant photosystem I supercomplex at 3.4 A resolution."
      Amunts A., Drory O., Nelson N.
      Nature 447:58-63(2007) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (3.4 ANGSTROMS) OF 49-235.
    7. "Structure determination and improved model of plant photosystem I."
      Amunts A., Toporik H., Borovikova A., Nelson N.
      J. Biol. Chem. 285:3478-3486(2010) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (3.3 ANGSTROMS).

    Entry informationi

    Entry nameiCAB6_ARATH
    AccessioniPrimary (citable) accession number: Q01667
    Secondary accession number(s): B9DHK2, Q9C5R7
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 30, 2010
    Last sequence update: November 1, 1996
    Last modified: October 1, 2014
    This is version 106 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    3D-structure, Complete proteome, Reference proteome

    Documents

    1. Arabidopsis thaliana
      Arabidopsis thaliana: entries and gene names
    2. PDB cross-references
      Index of Protein Data Bank (PDB) cross-references
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3