Q01605 (PHOE_CITFR) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Outer membrane pore protein E

Gene names

Name:

phoE

Organism

Citrobacter freundii

Taxonomic identifier

546 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Citrobacter

Protein attributes

Sequence length	351 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at transcript level

General annotation (Comments)

Function	Uptake of inorganic phosphate, phosphorylated compounds, and some other negatively charged solutes.
Subunit structure	Homotrimer.
Subcellular location	Cell outer membrane; Multi-pass membrane protein.
Induction	By phosphate starvation.
Sequence similarities	Belongs to the Gram-negative porin family.

Ontologies

Keywords
Biological process	Ion transport Stress response Transport
Cellular component	Cell membrane Cell outer membrane Membrane
Domain	Signal Transmembrane Transmembrane beta strand
Molecular function	Porin
Gene Ontology (GO)
Biological_process	ion transport Inferred from electronic annotation. Source: UniProtKB-KW response to stress Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	cell outer membrane Inferred from electronic annotation. Source: UniProtKB-SubCell plasma membrane Inferred from electronic annotation. Source: UniProtKB-KW pore complex Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	porin activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 21	21
	Chain	22 – 351	330	Outer membrane pore protein E		PRO_0000025241

Sequences

	Sequence		Length	Mass (Da)
	Q01605 [UniParc]. Last modified April 1, 1993. Version 1. Checksum: 4E9C144070381B5A	FASTA	351	38,807
	10 20 30 40 50 60 MKKSTLALVV MGITASASVQ AAEVYNKNGN KLDLYGKVKA MHYMTDYDSK DGDQSYIRLG 70 80 90 100 110 120 FKGETQINDE LTGYGRWEAE FAGNKAESDS NQQKTRLAFA GSKLKNLGSF DYGRNLGALY 130 140 150 160 170 180 DVEAWTDMFP EFGGDSSAQT DNFMTKRASG LATYRNTDFF GVVDGLDLTL QYQGKNQDRD 190 200 210 220 230 240 VKKQNGDGFG TSVTYDFGGS DFAVSGAYTN SDRTNQQNLQ TRGTGDKAEA WATGLKYDAN 250 260 270 280 290 300 DIYIATFYSE TRNMTPISGG FANKTQNFEA VVQYQFDFGL RPSLGYVLSK GKDIEGVGNE 310 320 330 340 350 DLVNYIDVGA TYYFNKNMSA FVDYKINQLD SDNKLGINND DIVAVGMVYQ F

References

[1]	"Characterization of the Citrobacter freundii phoE gene and development of C. freundii-specific oligonucleotides." Spierings G., Ockhuijsen C., Hofstra H., Tommassen J. FEMS Microbiol. Lett. 78:199-204(1992) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	X68021 Genomic DNA. Translation: CAA48162.1.
PIR	S25520.
3D structure databases
ProteinModelPortal	Q01605.
SMR	Q01605. Positions 22-351.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
Gene3D	2.40.160.10. 1 hit.
InterPro	IPR023614. Porin_dom. IPR001897. Porin_gammaproteobac. IPR001702. Porin_Gram-ve. IPR013793. Porin_Gram-ve_CS. [Graphical view]
Pfam	PF00267. Porin_1. 1 hit. [Graphical view]
PRINTS	PR00183. ECOLIPORIN. PR00182. ECOLNEIPORIN.
PROSITE	PS00576. GRAM_NEG_PORIN. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

PHOE_CITFR

Accession

Primary (citable) accession number: Q01605

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 1, 1993
Last sequence update:	April 1, 1993
Last modified:	April 3, 2013
This is version 73 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program