Reviewed, UniProtKB/Swiss-Prot Q01583 (DGK1_DROME)

Names and origin

Protein names

Recommended name:
    Diacylglycerol kinase 1
      Short name=DAG kinase 1
      Short name=Diglyceride kinase 1
      Short name=DGK 1
    EC=2.7.1.107

Gene names

Name:	Dgk
Synonyms:	DGK1
ORF Names:	CG34361

Organism

Drosophila melanogaster (Fruit fly) [Complete proteome]

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	1211 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Function	Upon cell stimulation converts the second messenger diacylglycerol into phosphatidate, initiating the resynthesis of phosphatidylinositols and attenuating protein kinase C activity By similarity. May have a role in the development of the embryonic nervous system and the function of the adult nervous system and muscle; regulating signal transduction in neurons.
Catalytic activity	ATP + 1,2-diacylglycerol = ADP + 1,2-diacyl-sn-glycerol 3-phosphate.
Tissue specificity	In 10-11 hours embryos, expression is abundant in a limited number of cells in the procephalic region and in the ventral nerve cord. Predominantly expressed in the adult nervous system and muscle: including compound eyes, brain cortex, fibrillar muscle, and tubular muscle. Ref.1 Ref.2
Developmental stage	Expressed in the embryonic, pupal and adult stages, with little expression during the larval stages. Ref.1 Ref.2
Sequence similarities	Belongs to the eukaryotic diacylglycerol kinase family. Contains 1 DAGKc domain. Contains 2 EF-hand domains. Contains 2 phorbol-ester/DAG-type zinc fingers.

Ontologies

Keywords
Coding sequence diversity	Alternative splicing
Domain	Phorbol-ester binding Repeat Zinc-finger
Ligand	ATP-binding Calcium Metal-binding Nucleotide-binding Zinc
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway Inferred from electronic annotation. Source: InterPro intracellular signaling cascade Inferred from electronic annotation. Source: InterPro phosphorylation Inferred from direct assay. Source: FlyBase
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW calcium ion binding Inferred from electronic annotation. Source: UniProtKB-KW diacylglycerol binding Inferred from electronic annotation. Source: UniProtKB-KW diacylglycerol kinase activity Inferred from direct assay. Source: FlyBase zinc ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Alternative products

This entry describes 4 isoforms produced by alternative splicing. [Align] [Select]

Isoform E (identifier: Q01583-4)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Note: No experimental confirmation available.

Isoform C (identifier: Q01583-3)

The sequence of this isoform differs from the canonical sequence as follows:
     1-698: Missing.

Isoform F (identifier: Q01583-1)

The sequence of this isoform differs from the canonical sequence as follows:
     121-250: GSIPNINSIA...SSNSVNCKID → AVSRILPAIGRHCPGSLESGSAQAEKR

Note: No experimental confirmation available.

Isoform G (identifier: Q01583-2)

The sequence of this isoform differs from the canonical sequence as follows:
     2-73: NIGIAAPKWD...FLDAFLDCEA → RWELRYGWQI...AGCCCIGKYF
     74-485: Missing.
     530-537: Missing.

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 1211	1211	Diacylglycerol kinase 1		PRO_0000218473
Regions
	Domain	286 – 321	36	EF-hand 1
	Domain	331 – 366	36	EF-hand 2
	Domain	548 – 682	135	DAGKc
	Calcium binding	299 – 310	12	1 Potential
	Calcium binding	344 – 355	12	2 Potential
	Zinc finger	382 – 432	51	Phorbol-ester/DAG-type 1
	Zinc finger	449 – 498	50	Phorbol-ester/DAG-type 2
	Compositional bias	731 – 792	62	Thr-rich
	Compositional bias	850 – 973	124	Gln-rich
Natural variations
	Alternative sequence	1 – 698	698	Missing in isoform C.		VSP_017884
	Alternative sequence	2 – 73	72	NIGIA…LDCEA → RWELRYGWQIVTFRTNCATA AAVACHQLLCPVSLTSAVEI MPNSFPPEGRRRERRSGNLV LRAGCCCIGKYF in isoform G.		VSP_017885
	Alternative sequence	74 – 485	412	Missing in isoform G.		VSP_017886
	Alternative sequence	121 – 250	130	GSIPN…NCKID → AVSRILPAIGRHCPGSLESG SAQAEKR in isoform F.		VSP_033247
	Alternative sequence	530 – 537	8	Missing in isoform G.		VSP_017887
Experimental info
	Sequence conflict	794	1	M → T in BAA01894. Ref.1
	Sequence conflict	863	1	Q → QQQQQ in CAA47750. Ref.2

Sequences

	Sequence		Length	Mass (Da)
	Isoform E [UniParc]. Last modified April 29, 2008. Version 5. Checksum: CC58412EE1E8F762	FASTA	1,211	132,960
	10 20 30 40 50 60 MNIGIAAPKW DKLSPREFLQ LQELASYSTR KLQDVLREFS SPSAASTPKC IPDGDIDFDG 70 80 90 100 110 120 FRRFLDAFLD CEAPLDLAKH LFVSFLKPNV TQAQLHGRAL NQMAAISSTA ACAPVTSHTK 130 140 150 160 170 180 GSIPNINSIA ELMPQCSGGG GGIGGTGGVA GAEGHAQARS SFVDKIHGIT DKLHHSLGGH 190 200 210 220 230 240 LSHDPSKTGS VHPMLTVTPS PLASGPSMFQ ASNPARRSVD SSPSHSATNH SQMSRNSSKK 250 260 270 280 290 300 SSNSVNCKID ADIKLLARKL SHFDPLTLKV PLKDVVCYLS LLEAGRPEDK LEFMFRLYDT 310 320 330 340 350 360 DSNGVLDTAE MDAIVNQMMA VAEYLGWDVS ELRPILQEMM VEIDYDADGT VSLDEWQRGG 370 380 390 400 410 420 MTTIPLLVLL GVDSTTLKED GIHVWRLKHF SKPAYCNLCL NMLVGLGKKG LCCVLCKYTV 430 440 450 460 470 480 HERCVQHAPA SCITTYVKSK KPKCGGDLLH HWVEGNCYGR CSKCRKRIKA YHGITGLTCR 490 500 510 520 530 540 WCHMMLHNRC ASSVKKECTL GEYSELIVPP TAICPAVLDR QRSVNQAHKK SQMHHHQATH 550 560 570 580 590 600 FQITPPDELS CPLLVFVNPK SGGRQGDRIL RKFQYMLNPR QVYDLSKGGP KEGLTLFKDL 610 620 630 640 650 660 PRFRVICCGG DGTVGWVLEA MDSIELASQP AIGVIPLGTG NDLARCLRWG GGYEGENIPK 670 680 690 700 710 720 LMDKFRRAST VMLDRWSIEV TNTPHSDDMR PKVTLHSNMQ KVIELSQSVV VDKSLMERFE 730 740 750 760 770 780 EIQRQSKQVA TSMGTAASST SIMMASKTET EMETMATMEF GSSTTTTNRT TTTKSISMST 790 800 810 820 830 840 FETQCLQQTL RTAMSSSSSN TSSGSPCNGN QDAETEVDSH AAAAADVREK SVPRRSGETE 850 860 870 880 890 900 KQSLETLLLQ HKQQMQQQQQ QQQQGVTSLA VEEAATATPV GSNQSDNSSQ RNKQNNILKQ 910 920 930 940 950 960 QITLSLDLSD HEDEPKDDGG GAGDGTKSNG NSIPATPATP ITPTTPNAAS SVLQQQQQQH 970 980 990 1000 1010 1020 LQFEQQQKPI KVQSDKDCTV PYNIINNYFS VGVDAAICVK FHLEREKNPH KFNSRMKNKL 1030 1040 1050 1060 1070 1080 WYFEYATSET FAASCKNLHE SIEIVCDGVA LDLANGPHLQ GVALLNIPYT HGGSNLWGEH 1090 1100 1110 1120 1130 1140 LSQKRIRKSA GPFGKSKKLR AGDKEFSATS FNSVDLSVAI QDFGDRLIEV IGLENCLHMG 1150 1160 1170 1180 1190 1200 QVRTGLRASG RRLAQCSEVI IKTKKTFPMQ IDGEPWMQMP CTIKVTHKNQ VPMLMAPRSE 1210 KGRGFFNLLC S
	Isoform C. Checksum: BA50553F32F19602	FASTA	513	56,324
	10 20 30 40 50 60 MQKVIELSQS VVVDKSLMER FEEIQRQSKQ VATSMGTAAS STSIMMASKT ETEMETMATM 70 80 90 100 110 120 EFGSSTTTTN RTTTTKSISM STFETQCLQQ TLRTAMSSSS SNTSSGSPCN GNQDAETEVD 130 140 150 160 170 180 SHAAAAADVR EKSVPRRSGE TEKQSLETLL LQHKQQMQQQ QQQQQQGVTS LAVEEAATAT 190 200 210 220 230 240 PVGSNQSDNS SQRNKQNNIL KQQITLSLDL SDHEDEPKDD GGGAGDGTKS NGNSIPATPA 250 260 270 280 290 300 TPITPTTPNA ASSVLQQQQQ QHLQFEQQQK PIKVQSDKDC TVPYNIINNY FSVGVDAAIC 310 320 330 340 350 360 VKFHLEREKN PHKFNSRMKN KLWYFEYATS ETFAASCKNL HESIEIVCDG VALDLANGPH 370 380 390 400 410 420 LQGVALLNIP YTHGGSNLWG EHLSQKRIRK SAGPFGKSKK LRAGDKEFSA TSFNSVDLSV 430 440 450 460 470 480 AIQDFGDRLI EVIGLENCLH MGQVRTGLRA SGRRLAQCSE VIIKTKKTFP MQIDGEPWMQ 490 500 510 MPCTIKVTHK NQVPMLMAPR SEKGRGFFNL LCS
	Isoform F. Checksum: 78CF327DBEDDF6ED	FASTA	1,108	122,602
	10 20 30 40 50 60 MNIGIAAPKW DKLSPREFLQ LQELASYSTR KLQDVLREFS SPSAASTPKC IPDGDIDFDG 70 80 90 100 110 120 FRRFLDAFLD CEAPLDLAKH LFVSFLKPNV TQAQLHGRAL NQMAAISSTA ACAPVTSHTK 130 140 150 160 170 180 AVSRILPAIG RHCPGSLESG SAQAEKRADI KLLARKLSHF DPLTLKVPLK DVVCYLSLLE 190 200 210 220 230 240 AGRPEDKLEF MFRLYDTDSN GVLDTAEMDA IVNQMMAVAE YLGWDVSELR PILQEMMVEI 250 260 270 280 290 300 DYDADGTVSL DEWQRGGMTT IPLLVLLGVD STTLKEDGIH VWRLKHFSKP AYCNLCLNML 310 320 330 340 350 360 VGLGKKGLCC VLCKYTVHER CVQHAPASCI TTYVKSKKPK CGGDLLHHWV EGNCYGRCSK 370 380 390 400 410 420 CRKRIKAYHG ITGLTCRWCH MMLHNRCASS VKKECTLGEY SELIVPPTAI CPAVLDRQRS 430 440 450 460 470 480 VNQAHKKSQM HHHQATHFQI TPPDELSCPL LVFVNPKSGG RQGDRILRKF QYMLNPRQVY 490 500 510 520 530 540 DLSKGGPKEG LTLFKDLPRF RVICCGGDGT VGWVLEAMDS IELASQPAIG VIPLGTGNDL 550 560 570 580 590 600 ARCLRWGGGY EGENIPKLMD KFRRASTVML DRWSIEVTNT PHSDDMRPKV TLHSNMQKVI 610 620 630 640 650 660 ELSQSVVVDK SLMERFEEIQ RQSKQVATSM GTAASSTSIM MASKTETEME TMATMEFGSS 670 680 690 700 710 720 TTTTNRTTTT KSISMSTFET QCLQQTLRTA MSSSSSNTSS GSPCNGNQDA ETEVDSHAAA 730 740 750 760 770 780 AADVREKSVP RRSGETEKQS LETLLLQHKQ QMQQQQQQQQ QGVTSLAVEE AATATPVGSN 790 800 810 820 830 840 QSDNSSQRNK QNNILKQQIT LSLDLSDHED EPKDDGGGAG DGTKSNGNSI PATPATPITP 850 860 870 880 890 900 TTPNAASSVL QQQQQQHLQF EQQQKPIKVQ SDKDCTVPYN IINNYFSVGV DAAICVKFHL 910 920 930 940 950 960 EREKNPHKFN SRMKNKLWYF EYATSETFAA SCKNLHESIE IVCDGVALDL ANGPHLQGVA 970 980 990 1000 1010 1020 LLNIPYTHGG SNLWGEHLSQ KRIRKSAGPF GKSKKLRAGD KEFSATSFNS VDLSVAIQDF 1030 1040 1050 1060 1070 1080 GDRLIEVIGL ENCLHMGQVR TGLRASGRRL AQCSEVIIKT KKTFPMQIDG EPWMQMPCTI 1090 1100 KVTHKNQVPM LMAPRSEKGR GFFNLLCS
	Isoform G. Checksum: 9DFD00E280FD64A6	FASTA	791	87,297
	10 20 30 40 50 60 MRWELRYGWQ IVTFRTNCAT AAAVACHQLL CPVSLTSAVE IMPNSFPPEG RRRERRSGNL 70 80 90 100 110 120 VLRAGCCCIG KYFLHNRCAS SVKKECTLGE YSELIVPPTA ICPAVLDRQR SVNQAHKATH 130 140 150 160 170 180 FQITPPDELS CPLLVFVNPK SGGRQGDRIL RKFQYMLNPR QVYDLSKGGP KEGLTLFKDL 190 200 210 220 230 240 PRFRVICCGG DGTVGWVLEA MDSIELASQP AIGVIPLGTG NDLARCLRWG GGYEGENIPK 250 260 270 280 290 300 LMDKFRRAST VMLDRWSIEV TNTPHSDDMR PKVTLHSNMQ KVIELSQSVV VDKSLMERFE 310 320 330 340 350 360 EIQRQSKQVA TSMGTAASST SIMMASKTET EMETMATMEF GSSTTTTNRT TTTKSISMST 370 380 390 400 410 420 FETQCLQQTL RTAMSSSSSN TSSGSPCNGN QDAETEVDSH AAAAADVREK SVPRRSGETE 430 440 450 460 470 480 KQSLETLLLQ HKQQMQQQQQ QQQQGVTSLA VEEAATATPV GSNQSDNSSQ RNKQNNILKQ 490 500 510 520 530 540 QITLSLDLSD HEDEPKDDGG GAGDGTKSNG NSIPATPATP ITPTTPNAAS SVLQQQQQQH 550 560 570 580 590 600 LQFEQQQKPI KVQSDKDCTV PYNIINNYFS VGVDAAICVK FHLEREKNPH KFNSRMKNKL 610 620 630 640 650 660 WYFEYATSET FAASCKNLHE SIEIVCDGVA LDLANGPHLQ GVALLNIPYT HGGSNLWGEH 670 680 690 700 710 720 LSQKRIRKSA GPFGKSKKLR AGDKEFSATS FNSVDLSVAI QDFGDRLIEV IGLENCLHMG 730 740 750 760 770 780 QVRTGLRASG RRLAQCSEVI IKTKKTFPMQ IDGEPWMQMP CTIKVTHKNQ VPMLMAPRSE 790 KGRGFFNLLC S

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Molecular cloning of a Drosophila diacylglycerol kinase gene that is expressed in the nervous system and muscle." Masai I., Hosoya T., Kojima S., Hotta Y. Proc. Natl. Acad. Sci. U.S.A. 89:6030-6034(1992) [PubMed: 1321433] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM G), FUNCTION, TISSUE SPECIFICITY, DEVELOPMENTAL STAGE. Strain: Oregon-R.
[2]	"A Drosophila gene encoding a protein with similarity to diacylglycerol kinase is expressed in specific neurons." Harden N., Yap S.F., Chiam M.-A., Lim L. Biochem. J. 289:439-444(1993) [PubMed: 8380995] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM C), FUNCTION, TISSUE SPECIFICITY, DEVELOPMENTAL STAGE. Strain: Canton-S. Tissue: Embryo.
[3]	"The genome sequence of Drosophila melanogaster." Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D. , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A., An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T., Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C. Science 287:2185-2195(2000) [PubMed: 10731132] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.
[4]	"Annotation of the Drosophila melanogaster euchromatic genome: a systematic review." Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P., Bettencourt B.R., Celniker S.E., de Grey A.D.N.J. , Drysdale R.A., Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E. Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002) [PubMed: 12537572] [Abstract] Cited for: GENOME REANNOTATION, ALTERNATIVE SPLICING.
[5]	Stapleton M., Brokstein P., Hong L., Agbayani A., Carlson J.W., Champe M., Chavez C., Dorsett V., Dresnek D., Farfan D., Frise E., George R.A., Gonzalez M., Guarin H., Kronmiller B., Li P.W., Liao G., Miranda A. , Mungall C.J., Nunoo J., Pacleb J.M., Paragas V., Park S., Patel S., Phouanenavong S., Wan K.H., Yu C., Lewis S.E., Rubin G.M., Celniker S.E. Submitted (JAN-2003) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM G). Strain: Berkeley. Tissue: Testis.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	D11120 mRNA. Translation: BAA01894.1. X67335 mRNA. Translation: CAA47750.1. AE013599 Genomic DNA. Translation: AAF59180.1. AE013599 Genomic DNA. Translation: AAS64897.1. AE013599 Genomic DNA. Translation: ABV53719.1. AE013599 Genomic DNA. Translation: ABV53720.1. BT003323 mRNA. Translation: AAO25083.1.
PIR	A46140. B46140.
RefSeq	NP_001097219.1. NP_001097220.1. NP_523654.2. NP_995775.1.
UniGene	Dm.3102
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q01583.
Genome annotation databases
Ensembl	FBtr0112580; FBpp0111492; FBgn0085390; Drosophila melanogaster. [Genome view]
GeneID	35738.
KEGG	dme:Dmel_CG34361.
Organism-specific databases
CTD	35738.
FlyBase	FBgn0085390. Dgk.
Phylogenomic databases
HOGENOM	Q01583.
Enzyme and pathway databases
BioCyc	DMEL-XXX-02:DMEL-XXX-02-003314-MON.
BRENDA	2.7.1.107. 48.
Gene expression databases
ArrayExpress	Q01583.
GermOnline	CG18654. Drosophila melanogaster.
Family and domain databases
InterPro	IPR000756. Diacylglycerol_kinase_access. IPR001206. Diacylglycerol_kinase_cat. IPR011992. EF-Hand_type. IPR018248. EF_hand. IPR018247. EF_HAND_1_Ca_BS. IPR018249. EF_HAND_2. IPR002048. EF_hand_Ca_bd. IPR002219. Prot_Kinase_C-like_PE/DAG_bd. [Graphical view]
Gene3D	G3DSA:1.10.238.10. EF-Hand_type. 1 hit.
Pfam	PF00130. C1_1. 2 hits. PF00609. DAGK_acc. 1 hit. PF00781. DAGK_cat. 1 hit. PF00036. efhand. 1 hit. [Graphical view]
ProDom	PD002939. DAGKa. 1 hit. PD005043. DAGKc. 1 hit. PD000012. EF-hand. 1 hit. [Graphical view] [Entries sharing at least one domain]
SMART	SM00109. C1. 2 hits. SM00045. DAGKa. 1 hit. SM00046. DAGKc. 1 hit. SM00054. EFh. 2 hits. [Graphical view]
PROSITE	PS50146. DAGK. 1 hit. PS00018. EF_HAND_1. 2 hits. PS50222. EF_HAND_2. 2 hits. PS00479. ZF_DAG_PE_1. 2 hits. PS50081. ZF_DAG_PE_2. 2 hits. [Graphical view]
ProtoNet	Search...
Other Resources
NextBio	794970.

Entry information

Entry name

DGK1_DROME

Accession

Primary (citable) accession number: Q01583
Secondary accession number(s): A8DY60 , A8DY61, Q53YF9, Q7KQR7, Q8MKP0, Q9V327

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 1, 1993
Last sequence update:	April 29, 2008
Last modified:	September 22, 2009
This is version 85 of the entry and version 5 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

Drosophila annotation project