Q01549 (PHY1_SELMA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Phytochrome 1

Gene names

Name:

PHY1

Organism

Selaginella martensii (Martens's spike moss)

Taxonomic identifier

3247 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Lycopodiophyta › Isoetopsida › Selaginellales › Selaginellaceae › Selaginella

Protein attributes

Sequence length	1134 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Regulatory photoreceptor which exists in two forms that are reversibly interconvertible by light: the Pr form that absorbs maximally in the red region of the spectrum and the Pfr form that absorbs maximally in the far-red region. Photoconversion of Pr to Pfr induces an array of morphogenic responses, whereas reconversion of Pfr to Pr cancels the induction of those responses. Pfr controls the expression of a number of nuclear genes including those encoding the small subunit of ribulose-bisphosphate carboxylase, chlorophyll A/B binding protein, protochlorophyllide reductase, rRNA, etc. It also controls the expression of its own gene(s) in a negative feedback fashion.
Subunit structure	Homodimer.
Post-translational modification	Contains one covalently linked phytochromobilin chromophore By similarity.
Sequence similarities	Belongs to the phytochrome family. Contains 1 GAF domain. Contains 1 histidine kinase domain. Contains 1 PAC (PAS-associated C-terminal) domain. Contains 2 PAS (PER-ARNT-SIM) domains.

Ontologies

Keywords
Biological process	Sensory transduction Transcription Transcription regulation
Domain	Repeat
Ligand	Chromophore
Molecular function	Photoreceptor protein Receptor
Gene Ontology (GO)
Biological process	peptidyl-histidine phosphorylation Inferred from electronic annotation. Source: InterPro protein-chromophore linkage Inferred from electronic annotation. Source: UniProtKB-KW protein-tetrapyrrole linkage Inferred from electronic annotation. Source: InterPro red, far-red light phototransduction Inferred from electronic annotation. Source: InterPro regulation of transcription, DNA-dependent Inferred from electronic annotation. Source: UniProtKB-KW transcription, DNA-dependent Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	membrane Inferred from electronic annotation. Source: InterPro
Molecular function	ATP binding Inferred from electronic annotation. Source: InterPro G-protein coupled photoreceptor activity Inferred from electronic annotation. Source: InterPro protein homodimerization activity Inferred from electronic annotation. Source: InterPro two-component sensor activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 1134	1134	Phytochrome 1		PRO_0000171994
Regions
	Domain	219 – 401	183	GAF
	Domain	616 – 687	72	PAS 1
	Domain	690 – 746	57	PAC
	Domain	750 – 821	72	PAS 2
	Domain	901 – 1121	221	Histidine kinase
	Compositional bias	352 – 358	7	Poly-Gly
Sites
	Binding site	324	1	Phytochromobilin chromophore (covalent; via 1 link) By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q01549 [UniParc]. Last modified July 1, 1993. Version 1. Checksum: 42819B9F4ACC398C	FASTA	1,134	124,707
	10 20 30 40 50 60 MSTTKLTYSS GSSAKSKHSV RVAQTTADAK LHAVYEESGE SGDSFDYSKS INATKSTGET 70 80 90 100 110 120 IPAQAVTAYL QRMQRGGLVQ PFGCMLAVEE GSFRVIAFSD NAGEMLDLMP QSVPSLGSGQ 130 140 150 160 170 180 QDVLTIGTDA RTLFTAAASA LEKAAGAVDL SMLNPIWVQS KTSAKPFYAI VHRIDVGLVM 190 200 210 220 230 240 DLEPVKASDT RVGSAAGALQ SHKLAAKAIS RLQSLPGGDI GLLCDTVVEE VRDVTGYDLV 250 260 270 280 290 300 MAYKFHEDEH GEVVAEIRRS DLEPYLGLHY PATDIPQASR FLFMKNRVRM ICDCSAPPVK 310 320 330 340 350 360 ITQDKELRQP ISLAGSTLRA PHGCHAQYMG NMGSVASLVM AMIINDNDEP SGGGGGGGQH 370 380 390 400 410 420 KGRRLWGLVV CHHTSPRSVP FLRSACEFLM QVFGLQLNME AAVAAHVREK HILRTQTLLC 430 440 450 460 470 480 DMLLRDAPIG IVSQSPNIMD LVKCDGAALY YGKRFWLLGI TPSEAQIKDI AEWLLEHHKD 490 500 510 520 530 540 STGLSTDSLA DAGYPGAASL GDEVCGMAAA KITAKDFLFW FRSHTAKEVK WGGAKHDPDD 550 560 570 580 590 600 KDDGRKMHPR SSFKAFLEVV KRRSLPWEDV EMDAIHSLQL ILRGSFQDID DSDTKTMIHA 610 620 630 640 650 660 RLNDLKLQGM DELSTVANEM VRLIETATAP ILAVDSSGFI NGWNAKVADV TGLPVTEAMG 670 680 690 700 710 720 RSLAKELVLH ESADMVERLL YLALQGDEEQ NVELKLKTFG GQKDKEAVIL VVNACASRDV 730 740 750 760 770 780 SDNVVGVCFV GQDVTGQKVV MDKFTRIQGD YKAIVQNPNP LIPPIFGADE FGYCSEWNPA 790 800 810 820 830 840 MEKLSGWRRE EVLGKMLVGE IFGIQMMYCR LKGQDAVTKF MIVLNSAADG QDTEKFPFAF 850 860 870 880 890 900 FDRQGKYVEA LLTATKRADA EGSITGVFCF LHIASAELQQ ALTVQRATEK VALSKLKELA 910 920 930 940 950 960 YIRQEIKNPL YGIMFTRTLM ETTDLSEDQK QYVETGAVCE KQIRKILDDM DLESIEDGYL 970 980 990 1000 1010 1020 ELDTTEFMMG TVMDAVISQG MITSKEKNLQ LIRETPKEIK AMFLYGDQVR LQQVLADFLL 1030 1040 1050 1060 1070 1080 NAIRFTPSSE NWVGIKVATS RKRLGGVVHV MHLEFRITHP GVGLPEELVQ EMFDRGRGMT 1090 1100 1110 1120 1130 QEGLGLSMCR KLVKLMNGEV EYIREAGKNY FLVSLELPLA QRDDAGSVKF QASS

References

[1]

"Phytochrome evolution: a phylogenetic tree with the first complete sequence of phytochrome from a cryptogamic plant (Selaginella martensii spring)." Hanelt S., Braun B., Marx S., Schneider-Poetsch H.A.W. Photochem. Photobiol. 56:751-758(1992) [PubMed: 1475321] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: Spring.

Cross-references

Sequence databases
EMBL GenBank DDBJ	X61458 Genomic DNA. Translation: CAA43698.1.
PIR	S31280.
3D structure databases
ProteinModelPortal	Q01549.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
InterPro	IPR003594. ATPase-like_ATP-bd. IPR003018. GAF. IPR001610. PAC. IPR000014. PAS. IPR000700. PAS-assoc_C. IPR013654. PAS_2. IPR013767. PAS_fold. IPR016132. Phyto_chromo_attachment. IPR013516. Phyto_chromo_BS. IPR001294. Phytochrome. IPR012129. Phytochrome_A-E. IPR013515. Phytochrome_cen-reg. IPR003661. Sig_transdc_His_kin_sub1_dim/P. IPR005467. Sig_transdc_His_kinase_core. [Graphical view]
Gene3D	G3DSA:3.30.565.10. ATP_bd_ATPase. 1 hit.
Pfam	PF01590. GAF. 1 hit. PF02518. HATPase_c. 1 hit. PF00512. HisKA. 1 hit. PF00989. PAS. 2 hits. PF08446. PAS_2. 1 hit. PF00360. PHY. 1 hit. [Graphical view]
PIRSF	PIRSF000084. Phytochrome. 1 hit.
PRINTS	PR01033. PHYTOCHROME.
SMART	SM00065. GAF. 1 hit. SM00387. HATPase_c. 1 hit. SM00388. HisKA. 1 hit. SM00086. PAC. 1 hit. SM00091. PAS. 2 hits. [Graphical view]
SUPFAM	SSF55874. ATP_bd_ATPase. 1 hit.
TIGRFAMs	TIGR00229. Sensory_box. 1 hit.
PROSITE	PS50109. HIS_KIN. 1 hit. PS50113. PAC. 1 hit. PS50112. PAS. 2 hits. PS00245. PHYTOCHROME_1. 1 hit. PS50046. PHYTOCHROME_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

PHY1_SELMA

Accession

Primary (citable) accession number: Q01549

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 1, 1993
Last sequence update:	July 1, 1993
Last modified:	September 21, 2011
This is version 81 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program