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Protein
Submitted name:

Thrombospondin related anonymous protein

Gene

TRAP

Organism
Plasmodium falciparum
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi56 – 561MagnesiumCombined sources
Metal bindingi58 – 581MagnesiumCombined sources
Metal bindingi162 – 1621MagnesiumCombined sources

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
Complete GO annotation...

Keywords - Ligandi

MagnesiumCombined sources, Metal-bindingCombined sources

Names & Taxonomyi

Protein namesi
Submitted name:
Thrombospondin related anonymous proteinImported
Submitted name:
Thrombospondin-related adhesive proteinImported
Gene namesi
Name:TRAPImported
OrganismiPlasmodium falciparumImported
Taxonomic identifieri5833 [NCBI]
Taxonomic lineageiEukaryotaAlveolataApicomplexaAconoidasidaHaemosporidaPlasmodiumPlasmodium (Laverania)

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi43 ↔ 235Combined sources
Disulfide bondi205 ↔ 212Combined sources

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4F1JX-ray1.73A/B41-242[»]
4F1KX-ray1.87A/B41-242[»]
ProteinModelPortaliQ01502.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Family and domain databases

Gene3Di3.40.50.410. 1 hit.
InterProiIPR000884. Thrombospondin_1_rpt.
IPR002035. VWF_A.
[Graphical view]
PfamiPF00090. TSP_1. 1 hit.
PF00092. VWA. 1 hit.
[Graphical view]
SMARTiSM00209. TSP1. 1 hit.
SM00327. VWA. 1 hit.
[Graphical view]
SUPFAMiSSF53300. SSF53300. 1 hit.
SSF82895. SSF82895. 1 hit.
PROSITEiPS50092. TSP1. 1 hit.
PS50234. VWFA. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q01502-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNHLGNVKYL VIVFLIFFDL FLVNGRDVQN NIVDEIKYRE EVCNDEVDLY
60 70 80 90 100
LLMDCSGSIR RHNWVKHAVP LAMKLIQQLN LNENAIHLYA NIFSNNAKEI
110 120 130 140 150
IRLHSDASKN KEKALIIIKS LLSTNLPYGR TNLSDALLQV RKHLNDRINR
160 170 180 190 200
ENANQLVVIL TDGIPDSIQD SLKESRKLND RGVKIAVFGI GQGINVAFNR
210 220 230 240 250
FLVGCHPSDG KCNLYADSAW ENVKNVIGPF MKAVCVEVEK TASCGVWDEW
260 270 280 290 300
SPCSVTCGKG TRSRKREILH EGCTSELQEQ CEEERCPPKW EPLDVPQEPE
310 320 330 340 350
DDQPRPRGDN FAVEKPEENI IDNNPQEPSP NPEEGKGENP NGFDLDENPE
360 370 380 390 400
NPPNPDIPEQ EPNIPEDSEK EVPSDVPKNP EDDREENFDI PKKPENKHDN
410 420 430 440 450
QNNLPNDKSD RYIPYSPLPP KVLDNERKQS DPQSQDNNGN RHVPNSEDRE
460 470 480 490 500
TRPHGRNNEN RSYNRKYNDT PKYPEREEHE KPDNNKKKGG SDNKYKIAGG
510 520 530 540 550
IAGGLALLAC AGLAYKFVVP GAATPFAGEP APFDETLGEE DKDLDEPEQF

RLPEENEWN
Length:559
Mass (Da):63,357
Last modified:November 1, 1996 - v1
Checksum:iC6DCFBB446921107
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei559 – 5591Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M96805 Genomic DNA. Translation: AAA29770.1.
AF544211 Genomic DNA. Translation: AAQ11893.1.
AB807840 Genomic DNA. Translation: BAO53694.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M96805 Genomic DNA. Translation: AAA29770.1.
AF544211 Genomic DNA. Translation: AAQ11893.1.
AB807840 Genomic DNA. Translation: BAO53694.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4F1JX-ray1.73A/B41-242[»]
4F1KX-ray1.87A/B41-242[»]
ProteinModelPortaliQ01502.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

Gene3Di3.40.50.410. 1 hit.
InterProiIPR000884. Thrombospondin_1_rpt.
IPR002035. VWF_A.
[Graphical view]
PfamiPF00090. TSP_1. 1 hit.
PF00092. VWA. 1 hit.
[Graphical view]
SMARTiSM00209. TSP1. 1 hit.
SM00327. VWA. 1 hit.
[Graphical view]
SUPFAMiSSF53300. SSF53300. 1 hit.
SSF82895. SSF82895. 1 hit.
PROSITEiPS50092. TSP1. 1 hit.
PS50234. VWFA. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Polymorphism of the TRAP gene of Plasmodium falciparum."
    Robson K.J., Hall J.R., Davies L.C., Crisanti A., Hill A.V., Wellems T.E.
    Proc. R. Soc. B 242:205-216(1990) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: Dd2Imported.
  2. "Polymorphisms within T-cell epitopes of pre-erythrocytic stage antigens of Plasmodium falciparum isolates."
    Singh B.
    Submitted (SEP-2002) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: LUN01Imported.
  3. "Structure of Plasmodium falciparum TRAP (thrombospondin-related anonymous protein) A domain highlights distinct features in apicomplexan von Willebrand factor A homologues."
    Pihlajamaa T., Kajander T., Knuuti J., Horkka K., Sharma A., Permi P.
    Biochem. J. 450:469-476(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (1.73 ANGSTROMS) OF 41-242 IN COMPLEX WITH MAGNESIUM, ACTIVE SITE.
  4. "Diversifying Selection on the Thrombospondin-Related Adhesive Protein (TRAP) Gene of Plasmodium falciparum in Thailand."
    Ohashi J., Suzuki Y., Naka I., Hananantachai H., Patarapotikul J.
    PLoS ONE 9:e90522-e90522(2014) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: YS013Imported.

Entry informationi

Entry nameiQ01502_PLAFA
AccessioniPrimary (citable) accession number: Q01502
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: April 1, 2015
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.