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Q01297

- CATA1_RICCO

UniProt

Q01297 - CATA1_RICCO

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Protein
Catalase isozyme 1
Gene
CAT1
Organism
Ricinus communis (Castor bean)
Status
Reviewed - Annotation score: 4 out of 5 - Experimental evidence at transcript leveli

Functioni

Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.

Catalytic activityi

2 H2O2 = O2 + 2 H2O.

Cofactori

Heme group.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei65 – 651 By similarity
Active sitei138 – 1381 By similarity
Metal bindingi348 – 3481Iron (heme axial ligand) By similarity

GO - Molecular functioni

  1. catalase activity Source: UniProtKB-EC
  2. heme binding Source: InterPro
  3. metal ion binding Source: UniProtKB-KW
Complete GO annotation...

GO - Biological processi

  1. hydrogen peroxide catabolic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase, Peroxidase

Keywords - Biological processi

Hydrogen peroxide

Keywords - Ligandi

Heme, Iron, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Catalase isozyme 1 (EC:1.11.1.6)
Gene namesi
Name:CAT1
OrganismiRicinus communis (Castor bean)
Taxonomic identifieri3988 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsMalpighialesEuphorbiaceaeAcalyphoideaeAcalypheaeRicinus

Subcellular locationi

Peroxisome Reviewed prediction. Glyoxysome Reviewed prediction

GO - Cellular componenti

  1. glyoxysome Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Glyoxysome, Peroxisome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 492492Catalase isozyme 1
PRO_0000084956Add
BLAST

Proteomic databases

PRIDEiQ01297.

Expressioni

Tissue specificityi

Abundant in endosperms and cotyledons. Only in small amount in root.

Interactioni

Subunit structurei

Homotetramer.

Structurei

3D structure databases

ProteinModelPortaliQ01297.

Family & Domainsi

Sequence similaritiesi

Belongs to the catalase family.

Family and domain databases

Gene3Di2.40.180.10. 1 hit.
InterProiIPR018028. Catalase.
IPR020835. Catalase-like_dom.
IPR024708. Catalase_AS.
IPR024711. Catalase_clade1/3.
IPR011614. Catalase_core.
IPR002226. Catalase_haem_BS.
IPR010582. Catalase_immune_responsive.
[Graphical view]
PANTHERiPTHR11465. PTHR11465. 1 hit.
PfamiPF00199. Catalase. 1 hit.
PF06628. Catalase-rel. 1 hit.
[Graphical view]
PIRSFiPIRSF038928. Catalase_clade1-3. 1 hit.
PRINTSiPR00067. CATALASE.
SMARTiSM01060. Catalase. 1 hit.
[Graphical view]
SUPFAMiSSF56634. SSF56634. 1 hit.
PROSITEiPS00437. CATALASE_1. 1 hit.
PS00438. CATALASE_2. 1 hit.
PS51402. CATALASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q01297-1 [UniParc]FASTAAdd to Basket

« Hide

MDPYRNRPSS GFNTPFWTTN SGAPVWNNNS SLTVGSRGPI LLEDYHLIEK    50
LANFDRERIP ERVVHARGAS AKGFFEVTHD VSHLTCADFL RAPGVQTPVI 100
VRFSTVIHER GSPETLRDPR GFAVKFYTRE GNFDLVGNNF PVFFIRDGMK 150
FPDVVHAFKP NPKSHLQENW RIFDFLSHVP ESLHMLTFLL DDLGIPQDYR 200
HMEGSGVNTY TLINKAGKVH YVKFHWKPTC GVKCLLENEA IKVGGSNHSH 250
ATQDLYDSIS AGNYPEWKLY IQIMDPAHED KFDFDPLDVT KTWPEDILPL 300
QPVGRLVLNK NIDNFFAENE QLAFCPGIVV PGVSYSEDKL LQTRIFSYSD 350
TQRHRLGPNY LQLPVNAPKC AHHNNHHEGF MNFMHRDEEV NYFPSRCDPA 400
RNAESFPVPS AICSGKREKC VIEKENNFKQ PGERYRSWAP DRQERFLNRL 450
VGGLSDPRIT HELRTIWISY WIQCDKSLGQ KLATRLNVKP SI 492
Length:492
Mass (Da):56,464
Last modified:February 1, 1996 - v2
Checksum:iB5E28A425088BF63
GO

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti439 – 4391A → P in CAA42215. 1 Publication
Sequence conflicti446 – 4461F → S in CAA42215. 1 Publication
Sequence conflicti454 – 4541L → F1 Publication
Sequence conflicti456 – 4561D → E1 Publication
Sequence conflicti461 – 4611H → Q in CAA42215. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
D21161 Genomic DNA. Translation: BAA04697.1.
X59694 mRNA. Translation: CAA42215.1.
PIRiS46297.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
D21161 Genomic DNA. Translation: BAA04697.1 .
X59694 mRNA. Translation: CAA42215.1 .
PIRi S46297.

3D structure databases

ProteinModelPortali Q01297.
ModBasei Search...

Proteomic databases

PRIDEi Q01297.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Family and domain databases

Gene3Di 2.40.180.10. 1 hit.
InterProi IPR018028. Catalase.
IPR020835. Catalase-like_dom.
IPR024708. Catalase_AS.
IPR024711. Catalase_clade1/3.
IPR011614. Catalase_core.
IPR002226. Catalase_haem_BS.
IPR010582. Catalase_immune_responsive.
[Graphical view ]
PANTHERi PTHR11465. PTHR11465. 1 hit.
Pfami PF00199. Catalase. 1 hit.
PF06628. Catalase-rel. 1 hit.
[Graphical view ]
PIRSFi PIRSF038928. Catalase_clade1-3. 1 hit.
PRINTSi PR00067. CATALASE.
SMARTi SM01060. Catalase. 1 hit.
[Graphical view ]
SUPFAMi SSF56634. SSF56634. 1 hit.
PROSITEi PS00437. CATALASE_1. 1 hit.
PS00438. CATALASE_2. 1 hit.
PS51402. CATALASE_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Isolation and characterization of two tightly linked catalase genes from castor bean that are differentially regulated."
    Suzuki M., Ario T., Hattori T., Nakamura K., Asahi T.
    Plant Mol. Biol. 25:507-516(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Tissue: Hypocotyl.
  2. "The C-terminal domain of plant catalases. Implications for a glyoxysomal targeting sequence."
    Gonzalez E.
    Eur. J. Biochem. 199:211-215(1991) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 404-492.
    Strain: cv. Hale.

Entry informationi

Entry nameiCATA1_RICCO
AccessioniPrimary (citable) accession number: Q01297
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 1, 1993
Last sequence update: February 1, 1996
Last modified: February 19, 2014
This is version 84 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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