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Protein

Movement protein

Gene
N/A
Organism
Impatiens necrotic spot virus (INSV)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Viral movemement protein which is responsible for cell-to cell spread of viral genome. Increases the size exclusion limit (SEL) of plasmodesmata by forming tubules structures, thereby allowing viral ribonucleocapsids to spread directly to neighboring cells (By similarity).By similarity

GO - Biological processi

  1. transport of virus in host, cell to cell Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Viral movement protein

Keywords - Biological processi

Host-virus interaction, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Movement protein
Short name:
MVP
Alternative name(s):
Non-structural movement protein
Short name:
NSm
OrganismiImpatiens necrotic spot virus (INSV)
Taxonomic identifieri11612 [NCBI]
Taxonomic lineageiVirusesssRNA negative-strand virusesBunyaviridaeTospovirus
Virus hostiImpatiens [TaxID: 35939]

Subcellular locationi

Host cell junctionhost plasmodesma By similarity
Note: Colocalizes with viral nucleocapsid aggregates in host cytoplasm.

GO - Cellular componenti

  1. host cell plasmodesma Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Host cell junction

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 303303Movement proteinPRO_0000221986Add
BLAST

Interactioni

Subunit structurei

Oligomerizes to form tubule structures through host plasmodesma. Interacts with host A.thaliana At4g26020 protein, which is involved in antra- and inter-cellular trafficking (By similarity).By similarity

Family & Domainsi

Sequence similaritiesi

Belongs to the tospovirus movement protein family.Curated

Family and domain databases

InterProiIPR000603. 3A/RNA2_movement_prot.
IPR006889. Bunya_NSM.
[Graphical view]
PfamiPF00803. 3A. 1 hit.
[Graphical view]
PIRSFiPIRSF003959. NS-M_TospoV. 1 hit.

Sequencei

Sequence statusi: Complete.

Q01268-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNSFFKSLRS SSSRELDHPR VTTTLSKQGA DIVVHNPSAN HNNKEVLQRA
60 70 80 90 100
MDSSKGKILM NNTGTSSLGT YESDQISESE SYDLSARMIV DTNHHISSWK
110 120 130 140 150
NDLFVGNGDK AATKIIKIHP TWDSRKQYMM ISRIVIWICP TIADPDGKLA
160 170 180 190 200
VALIDPNKSV NARTVLKGQG SIKDPICFVF YLNWSIPKVN NTSENCVQLH
210 220 230 240 250
LLCDQVYKKD VSFASVMYSW TKEFCDSPRA DLDKSCMIIP INRAIRAKSQ
260 270 280 290 300
AFIEACKLII PKGNSEKQIR RQLAELSANL EKSVEEEENV TDNKIEISFD

NEI
Length:303
Mass (Da):34,105
Last modified:February 1, 1994 - v1
Checksum:iBCD9CFD44E671C64
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M74904 Genomic RNA. Translation: AAA46241.1.
PIRiA42544.
RefSeqiNP_619690.1. NC_003616.1.

Genome annotation databases

GeneIDi956572.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M74904 Genomic RNA. Translation: AAA46241.1.
PIRiA42544.
RefSeqiNP_619690.1. NC_003616.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi956572.

Family and domain databases

InterProiIPR000603. 3A/RNA2_movement_prot.
IPR006889. Bunya_NSM.
[Graphical view]
PfamiPF00803. 3A. 1 hit.
[Graphical view]
PIRSFiPIRSF003959. NS-M_TospoV. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "The M RNA of impatiens necrotic spot Tospovirus (Bunyaviridae) has an ambisense genomic organization."
    Law M.D., Speck J., Moyer J.W.
    Virology 188:732-741(1992) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].

Entry informationi

Entry nameiMVP_INSV
AccessioniPrimary (citable) accession number: Q01268
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1994
Last sequence update: February 1, 1994
Last modified: January 7, 2015
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.