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Protein
Submitted name:

Peptide synthetase

Gene

pesA

Organism
Metarhizium anisopliae (Entomophthora anisopliae)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Peptide synthetaseImported
Gene namesi
Name:pesAImported
OrganismiMetarhizium anisopliae (Entomophthora anisopliae)Imported
Taxonomic identifieri5530 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaSordariomycetesHypocreomycetidaeHypocrealesClavicipitaceaeMetarhizium

Structurei

3D structure databases

ProteinModelPortaliQ01135.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini609 – 67769Acyl carrierInterPro annotationAdd
BLAST
Domaini2093 – 216068Acyl carrierInterPro annotationAdd
BLAST
Domaini3167 – 323569Acyl carrierInterPro annotationAdd
BLAST
Domaini4222 – 428867Acyl carrierInterPro annotationAdd
BLAST

Family and domain databases

Gene3Di1.10.1200.10. 4 hits.
InterProiIPR010071. AA_adenyl_domain.
IPR020845. AMP-binding_CS.
IPR000873. AMP-dep_Synth/Lig.
IPR001242. Condensatn.
IPR020806. PKS_PP-bd.
IPR009081. PP-bd_ACP.
IPR006162. Ppantetheine_attach_site.
[Graphical view]
PfamiPF00501. AMP-binding. 4 hits.
PF00668. Condensation. 6 hits.
PF00550. PP-binding. 4 hits.
[Graphical view]
SMARTiSM00823. PKS_PP. 2 hits.
[Graphical view]
SUPFAMiSSF47336. SSF47336. 4 hits.
TIGRFAMsiTIGR01733. AA-adenyl-dom. 4 hits.
PROSITEiPS50075. ACP_DOMAIN. 4 hits.
PS00455. AMP_BINDING. 4 hits.
PS00012. PHOSPHOPANTETHEINE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q01135-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLNITLSYST STLIEEEAVN IGATFAKAAS LIVLNPNQKL HDLDLISDRD
60 70 80 90 100
LASIWGWNEP QPRVIDSCVH HIIQSRVEQQ PDALAICGWD ASITYRQLDD
110 120 130 140 150
YSNRLAHHLL GFGVGPEVIV PLCFEKSAWA IVALLGVVKA GGAFVFIDPS
160 170 180 190 200
HPKGRRDDII SQIASTLVLT SIAQADQWTD SSLEVVPLGP QLVDALAPQT
210 220 230 240 250
QPPVTTVCPN NILYVIFTSG STGRPKACVV EHSSFCSGAV AQAEVANMDS
260 270 280 290 300
SSRVLQLASF SFDVSLLEIM TALMHGACIC MPSAASMNEG VAKLINKFQI
310 320 330 340 350
TWAFLTPSLV KVIDPRDVPD LKTLILGGEA LSKSDIDTWA EHVQLGNGYG
360 370 380 390 400
PSECSVAAAG NPNLTPSTSP SNIGRAVGGL CWIVNAEDHN KLVPVGCVGE
410 420 430 440 450
LLIEGPIVAR GYLNAPEKTA EVFITGPDWG PLTRQGAPRR LYKTGDLARY
460 470 480 490 500
NPDGTIHFIG RKDTQVKLRG LRIELGEIEH HISVHGFTQH AIVILPKSGP
510 520 530 540 550
CKERLVVALS LKDFLPDTSK TSNVRLIPEE AQERASKQVA DIKEQLSRHV
560 570 580 590 600
PHYMVPETWI VVEAIPLMLS GKMARSQVSK WIAEMDDETY DRAVGVHSQG
610 620 630 640 650
EGATEMTEHE IQLQLVYSEL LNLALSRIPL DRSFLSLGGD SISAMQVVSR
660 670 680 690 700
CRSRGMAVTV KDIIALKGIS ELALRVVRVA NSAHDQEESF DTPFALSPVQ
710 720 730 740 750
RMYVATTHLA SNGSSTRYNQ SFFLTVTRQT ADEELRKGFQ MVVAKHSMLR
760 770 780 790 800
ARFIESQDGT WQQVVLKQVE GTYNVVLHNV TAVEDIDAII EDAQSSLDLI
810 820 830 840 850
RGPVFAAHVF NVKSQGQFLF LVAHHAIIDL VSWRVVMKDL EDAVTSGEIA
860 870 880 890 900
NHVSLPYQKW LQLQADNARD HGSPGEVLPF NVTPPDMQYW GMQHQKNYIS
910 920 930 940 950
DTSEDTVKLS LDLTESLMGS QCHTALRTEP IDLILSILMY SFAHVFNDRA
960 970 980 990 1000
TPPFFRESHG RESWTDEIDI SETVGWFTTM FPLCTSATFE DDIVEFTRQI
1010 1020 1030 1040 1050
KDNRHAIPAN GRPYFASRFL NQEGMEAFAD HSQVEICFDY LGLYQQLEKS
1060 1070 1080 1090 1100
DALLRQEPRT MTANTSDIGP NVRRFALIEI TAEMINNQMQ FSFVYNHNMK
1110 1120 1130 1140 1150
HMPKLKEWIA SLPDSFSECI DQLSNARIQH TLSDFPMIKM SYEGLERLSN
1160 1170 1180 1190 1200
DILPQTGISF EQVQDIYPCS PMQQGLLISQ SKSTGVYKYC HTAEIISRSA
1210 1220 1230 1240 1250
NSVDSGNKFK NQAPIEFTDT EPPNRLSLCQ TNEGRVFCQF EFNHAIIDGG
1260 1270 1280 1290 1300
SMPIILQDFI LAYDGRTPDR PAALFQEYIS YLRSLPKGPG LSYWMNYLKN
1310 1320 1330 1340 1350
IEPTYLPSIQ GSSKDPQFLE MEVNINMETS VLLDFCQQNN LTLSNIFHVA
1360 1370 1380 1390 1400
WGLVLRAHTG RNDVCFGYLL SGREAPIRDI ERAVGPFITM LVSRLGLEND
1410 1420 1430 1440 1450
VPILDILQKV QGDFLLGMEH QHCPLADIQH ELGLAGQPLF NTVMSFQKAQ
1460 1470 1480 1490 1500
EGAGEDESTI SVVGLEAYDP PEYEVTLDVM VSEADVVTTL GYWTSSISTE
1510 1520 1530 1540 1550
QAKNLGLIFS RAVECIVKNI NSTVDDIDLV GGEHMTQILQ WNADLPPAHY
1560 1570 1580 1590 1600
HCIHHLFHEQ VVKQPDAPAI CSFDGNFTYA ELDDLSTKLA HHLVSMGVGP
1610 1620 1630 1640 1650
QVYVPFCFHK SAWTTVVIMA ILKAGGACVP MDPAQPVSRL EAISTMCSAK
1660 1670 1680 1690 1700
VAVTAPQNAH LLEGLVDVII SVDQGFINGL PTVAGMPCAS VQPDNVAYVI
1710 1720 1730 1740 1750
FSSGTTGTPK GIQLYHYSLA TFALWNNLIV KGNGPGQRVL QFAAYTFDVS
1760 1770 1780 1790 1800
ISDILGSLMF GACICNISDH DRMNNLSQAI RDVKATAIDL TATVAALIRP
1810 1820 1830 1840 1850
ADVPSVRILQ LGGEALTKEV VDIWAGNLDT LVNVYGPAEC SVTCSYSCNI
1860 1870 1880 1890 1900
LDDTDLANIG RVVGGLGWVV EPNNHDKLAP LGCVGELLIE GAILSAGYFG
1910 1920 1930 1940 1950
DAEKTKKSFI CNPIWSRTQP GVDRRFYKTG DLVRYNSDGS LHILGRGDTQ
1960 1970 1980 1990 2000
IKLYGQRLDL TDIEAQIIDH QPSLRQVTVE AIMPKGTTRK TLAAFFVMDD
2010 2020 2030 2040 2050
PDDGSTVDSL DSTPISLTPQ LQKDLQELQS SLALSLPRYM IPATYIRMSQ
2060 2070 2080 2090 2100
MPMNSSGKTN RAALRTMAAQ FSETQWSDYS LENKVKELPS TDLEKRLQQL
2110 2120 2130 2140 2150
WSAVLCIDID MIGAKDSFFG LGGDSVAMRL VAAARASNIL ISVMNIFKYP
2160 2170 2180 2190 2200
NLCDMALTVE IHETITRDLV ELDSFALLEP SSREETIEDC ADKCKVDKDC
2210 2220 2230 2240 2250
IEDIYPCTPL QEGLMAISTR LPRAYVARMV FKIPSTIDLN RFRNAWQQLI
2260 2270 2280 2290 2300
SLEPILRTRV ILTNTNSVQV VLRQENPWKE GLTLESYLEK DNGLPIEYGG
2310 2320 2330 2340 2350
LLHRLCIIDG LGQDSYFIWS VHHALYDGWS QNLLFERVKQ LYMGDAISKS
2360 2370 2380 2390 2400
PSYNRFIHFL AQEDTKSANK FWKSQLLREQ APTSFPVLPS PSYKPRADHV
2410 2420 2430 2440 2450
QTLRLPLSRQ KHSTITSATL IKAAWAMVVS QYSRSDDIIL ALTLSGRTAP
2460 2470 2480 2490 2500
VPGIMKMTGP TITTVPLRIE LPSRNTTVYK YLELVQNQAM EMMPYEHVGI
2510 2520 2530 2540 2550
QSLRRLCLEA EPDYELDLKH LLVIQSLGEV DGFLDLELLP TEEDDFNTYA
2560 2570 2580 2590 2600
LIVQCSVEEE NVCIEARYDR DVIETGQMER MLWQFQHVLR QLNDESHSST
2610 2620 2630 2640 2650
MEGVDLVSPQ DLEQLDVWNS QKHESMDICI HQVIEEQMRS RPVDAPAICA
2660 2670 2680 2690 2700
WDGELSYQEL DRLSNGLATH LVDLGVGPEV MVPICFDKSA WTIVTMIAVL
2710 2720 2730 2740 2750
KAGGAYVSLS SAHPLSRLRG IIDDIDAGLI LVAPQYAELF VDVVPRIIVV
2760 2770 2780 2790 2800
EPSWVTTLPT SISTPSFGRP DSAAFVVFTS GSTGKPKGLV IEHRSMVTMA
2810 2820 2830 2840 2850
HAEGPSMQFD SNTRTLNFGA STFDVSNSEV LTTLMFGGCV CVPSETERLN
2860 2870 2880 2890 2900
DLTGVINKWK VNWLFLTPAM ADLLDPAKVP TLQTLALGGE AIRQDLVERW
2910 2920 2930 2940 2950
ATKVHLINSY GPSETTIWTS NSHLSPEKRP ANIGRGYGAH TWVTDVTDHN
2960 2970 2980 2990 3000
RLAPIGCVGE LLVEGPILAR GYVKNPDITS AAFIFDPLWA KDGQKEQRRM
3010 3020 3030 3040 3050
YKTGDLVKYN VDGTLDYIGR KDTQVKLRGQ RIEPSEIEDH IRQSLPDVQH
3060 3070 3080 3090 3100
VAVEIVSKEG HKEDRALAAF LQLGQKDQHL VHDTNSDLVP ITEDLRKSML
3110 3120 3130 3140 3150
HLQQLLMGSL PPYMVPQLFI MLHQAPTTSS GKLDRKAMRE MASKLSKPQL
3160 3170 3180 3190 3200
APYMLVDVEK VAPATPMEKK LQSLWASLLR IDVSAIGAND NFFQSGGDSI
3210 3220 3230 3240 3250
IAMRLVAEAR ASHLPMSVAD IFRFPKLSEM ARAIQDVVFT PATDIEPFSL
3260 3270 3280 3290 3300
LRDEHSLDDI IQMAASVCDV KVEAIEDIYP CTALQKGLFS ITIRDPGAYI
3310 3320 3330 3340 3350
AQKVFQLPEA LDLDRFKRAW QILADMHPIL RTRILDTDLQ VVVREEPAWQ
3360 3370 3380 3390 3400
SASTLQAYLE HDLSENMNFG RPLCRYAIVE GHFIWTAHHA VYDAWSNQLL
3410 3420 3430 3440 3450
FDQLRGIYDG DEIPKAVPYS KLIEHLEKID QSAAMAFWKG QLSGDKPTSF
3460 3470 3480 3490 3500
PEARSLTYKP RPNQAFTYSM AVTDNYKSGT LMSSTLQARW ALAVARHSNS
3510 3520 3530 3540 3550
SDVAFAMALS GRNLSMQGIE SVIGPTITTV PIVMNLDMEQ TVADYLGNTQ
3560 3570 3580 3590 3600
KQMTEMIPFA HVGLQNLHSL DNYVDLKHLF VIQSAANEDA EGVLGMIPVP
3610 3620 3630 3640 3650
YDIAGFDSYG LVVECVQGTD KVDAEVRFDT AIISHERIQK MLNLFEHLVG
3660 3670 3680 3690 3700
QLNQDEYRSL PLKHVSFFSP QDAEQIAAWN REPPREKNET MHNLVQAQVS
3710 3720 3730 3740 3750
ARPLAPAILA SDGNFTYAEL DSRSTQLAHH LVQVGVKPEV MVLVCYNKSA
3760 3770 3780 3790 3800
WTIVAMLAIL KAGGACVAIN PEHPPERLQA IAQDVKASIV VTQQQHRHIF
3810 3820 3830 3840 3850
QGWNVNVVLP TESLTNKYPA TGTFTSARPE NPAFVVFTSG STGTPKGICL
3860 3870 3880 3890 3900
EHRALCASAQ AHGKAMRLGT DSRVLQFAAY TFDVSIGEIF TTLIYGGCVC
3910 3920 3930 3940 3950
VPTEEERLND LAAFINRMQI NWAYLTPTVA SFLQPADVPT LKTLSLGGEA
3960 3970 3980 3990 4000
VTKENVAVWA NRVHLINIYG PAETSIWSTA LCGLEPDTPP TNIGYGVGAL
4010 4020 4030 4040 4050
MWITEIANHD HLCPVGCVGE LLIEGPILAR GYVALDETTR ARFITNPAWA
4060 4070 4080 4090 4100
KGQGDRRFYK TGDLVKYNFD GTIDYVGRKD TQFKLHGQRI ESSEIEHHLS
4110 4120 4130 4140 4150
TDRHIRHAMI LLSKSKSGQQ RLTAIISLES VPPSAARDVP QLIQAESAQL
4160 4170 4180 4190 4200
EVSLIRKKLA ESVPGYMVPS IWLVVDHMSM TVSGKLNRLE MTKWVEQMDE
4210 4220 4230 4240 4250
DVFATSADAE DLEGSHIPAT VMEDKIQKML CQVLNLQTVR LDRSFLSLGG
4260 4270 4280 4290 4300
DSITAMQLRA KCRAEKIELS TQHILRAKSI SQMALLAKST SETALAHPEI
4310 4320 4330 4340 4350
LDSSFGLTPI QQMYFEIESK AEMSHHFHQS FLLRITKRIG TLQMARAIEK
4360 4370 4380 4390 4400
LVGQHSLLRA RFSQGENNQW TQRITGDVAD SHRFSMHQLA RREQMMPLIE
4410 4420 4430 4440 4450
ASQRAINITE GPVFCATLFN IGSNDDVGDS HQLLFLCAHH LVIDLVSWRH
4460 4470 4480 4490 4500
ILRDLEQLLD SGRLSSPKPP SFQTWATMQA EYAKELLPQD VMPLQIPPAD
4510 4520 4530 4540 4550
FGFWGMLNQA NVFEDQLETS FSLDEETTDK LFGVSNEALQ TEPVDIILSA
4560 4570 4580 4590 4600
LIDSFHRVFT DRPTPTIFSE GHGRESLAPE SDAAEIVGWF TTLNPLHVPV
4610 4620 4630 4640 4650
MEEEDELKIL AHTKDLRRQV PSSGYPYFCS RFLSPQGQQT FGHHTRMEVI
4660 4670 4680 4690 4700
LNYQGRYQQL ERDDALLRPE PLAENEVHKD QGSDMHRFSL FEISVEVVQG
4710 4720 4730 4740 4750
KTRVSFAYNR RMHHQDLIRQ WVSESKECLG TLTSRLSVTE LQLTRSSFPL
4760 4770 4780 4790 4800
LSLEDRELSQ FQSHLSSLAI RPSQIEAAYP TSPMQESMIS AQQKVPGIYG
4810 4820 4830 4840 4850
VRNMYDVIPG PQAGPVDHCR LMTAWQRVVD RHVSLRTVFV PSVSRKDSFD
4860 4870 4880 4890 4900
QVVLHTHTAR ISVIECDDDN VSEKMRSQEM IGFLEPVPHH RLAIFTTASK
4910 4920 4930 4940 4950
VMCCLDISHA LTDGMSMRLL MRDLYMAYES NLQLAPGPMY SDYIAFLQQQ
4960 4970 4980 4990 5000
PASQDAIFWR QYLDAVKPCH LPRPDAPLCS EREQRSVHVH LKEDFAQIQG
5010 5020 5030 5040 5050
FCKTYGLTVA NLIQSTWGLV LRKYTGCDDA VFGYLTSGRD MPIDGVMDLV
5060 5070 5080 5090 5100
GALIHMLLYR QVVDSATTVL ALLQQTRNDF LQSLPHQYGL VPAIKEHTRG
5110 5120 5130 5140 5150
AAQGLFNTIM SMQYSNGAGE ESESDDSKEP LLKFENKGGQ DPNQVCFWPL

CMVRKAY
Length:5,157
Mass (Da):573,968
Last modified:January 1, 1998 - v2
Checksum:i1038242BA3143868
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X89442 Genomic DNA. Translation: CAA61605.1.
PIRiPC4198.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X89442 Genomic DNA. Translation: CAA61605.1.
PIRiPC4198.

3D structure databases

ProteinModelPortaliQ01135.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

Gene3Di1.10.1200.10. 4 hits.
InterProiIPR010071. AA_adenyl_domain.
IPR020845. AMP-binding_CS.
IPR000873. AMP-dep_Synth/Lig.
IPR001242. Condensatn.
IPR020806. PKS_PP-bd.
IPR009081. PP-bd_ACP.
IPR006162. Ppantetheine_attach_site.
[Graphical view]
PfamiPF00501. AMP-binding. 4 hits.
PF00668. Condensation. 6 hits.
PF00550. PP-binding. 4 hits.
[Graphical view]
SMARTiSM00823. PKS_PP. 2 hits.
[Graphical view]
SUPFAMiSSF47336. SSF47336. 4 hits.
TIGRFAMsiTIGR01733. AA-adenyl-dom. 4 hits.
PROSITEiPS50075. ACP_DOMAIN. 4 hits.
PS00455. AMP_BINDING. 4 hits.
PS00012. PHOSPHOPANTETHEINE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ01135_METAN
AccessioniPrimary (citable) accession number: Q01135
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: January 1, 1998
Last modified: July 6, 2016
This is version 89 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.