Reviewed, UniProtKB/Swiss-Prot Q01116 (PMP20_LIPKO)

Names and origin

Protein names	Recommended name:     Putative peroxisomal peroxiredoxin     EC=1.11.1.15 Alternative name(s):     Thioredoxin reductase
Organism	Lipomyces kononenkoae
Taxonomic identifier	34357 [NCBI]
Taxonomic lineage	Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Lipomycetaceae › Lipomyces

Protein attributes

Sequence length	166 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Catalytic activity	2 R'-SH + ROOH = R'-S-S-R' + H2O + ROH.
Subcellular location	Peroxisome Potential.
Sequence similarities	Belongs to the peroxiredoxin 2 family. Contains 1 thioredoxin domain.

Ontologies

Keywords
Cellular component	Peroxisome
Domain	Redox-active center
Molecular function	Oxidoreductase Peroxidase
Gene Ontology (GO)
Biological process	cell redox homeostasis Inferred from electronic annotation. Source: InterPro oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	peroxisome Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	peroxiredoxin activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 166	166	Putative peroxisomal peroxiredoxin		PRO_0000056608
Regions
	Domain	5 – 166	162	Thioredoxin

Sequences

	Sequence		Length	Mass (Da)
	Q01116-1 [UniParc]. Last modified July 19, 2004. Version 2. Checksum: 72BBC556F979E0E3	FASTA	166	17,408
	10 20 30 40 50 60 MTDKFPEDVK FLYIAYTPAK ADITACGIPI PLDFDKEFRD KTVVIVAIPG AFTPTCTANH 70 80 90 100 110 120 IPPFVEKFTA LKSAGVDAVI VLSANDPFVQ SAFGKALGVT DEAFIFASDP GAEFSKSAGL 130 140 150 160 SLDLPPAFGT RTARYAIIVS NGVVKYVEKD SEGVAGSGVD AVLAAL

References

[1]	"Nucleotide sequence of a putative peroxisomal protein from the yeast Lipomyces kononenkoae." Randez-Gil F., Prieto J., Sanz P. FEMS Microbiol. Lett. 122:153-157(1994) [PubMed: 7958767] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA]. Strain: CBS 5608.

Cross-references

Sequence databases
EMBLGenBankDDBJ	U11244 mRNA. Translation: AAB41351.1.
3D structure databases
HSSP	HSSP built from PDB template 1NM3 based on UniProtKB P44758.
ModBase	Search...
Enzyme and pathway databases
BRENDA	1.11.1.15. 97343.
Family and domain databases
InterPro	IPR013740. Redoxin. IPR017936. Thioredoxin-like. IPR012335. Thioredoxin_fold. [Graphical view]
Gene3D	G3DSA:3.40.30.10. Thioredoxin_fold. 1 hit.
Pfam	PF08534. Redoxin. 1 hit. [Graphical view]
PROSITE	PS51352. THIOREDOXIN_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

PMP20_LIPKO

Accession

Primary (citable) accession number: Q01116

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 15, 1998
Last sequence update:	July 19, 2004
Last modified:	June 16, 2009
This is version 40 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

FPAP (Fungal Proteome Annotation Project)