ID   IL9R_HUMAN              Reviewed;         521 AA.
AC   Q01113; B9ZVT0; Q14634; Q8WWU1; Q96TF0;
DT   01-APR-1993, integrated into UniProtKB/Swiss-Prot.
DT   17-OCT-2006, sequence version 3.
DT   27-MAR-2024, entry version 211.
DE   RecName: Full=Interleukin-9 receptor;
DE            Short=IL-9 receptor;
DE            Short=IL-9R;
DE   AltName: CD_antigen=CD129;
DE   Flags: Precursor;
GN   Name=IL9R;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), AND VARIANT ARG-331.
RX   PubMed=1376929; DOI=10.1073/pnas.89.12.5690;
RA   Renauld J.-C., Druez C., Kermouni A., Houssiau F., Uyttenhove C.,
RA   van Roost E., van Snick J.;
RT   "Expression cloning of the murine and human interleukin 9 receptor cDNAs.";
RL   Proc. Natl. Acad. Sci. U.S.A. 89:5690-5694(1992).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   TISSUE=Melanoma;
RX   PubMed=8666384; DOI=10.1006/geno.1995.9992;
RA   Kermouni A., van Roost E., Arden K.C., Vermeesch J.R., Weiss S.,
RA   Godelaine D., Flint J., Lurquin C., Szikora J.-P., Higgs D.R., Marynen P.,
RA   Renauld J.-C.;
RT   "The IL-9 receptor gene (IL9R): genomic structure, chromosomal localization
RT   in the pseudoautosomal region of the long arm of the sex chromosomes, and
RT   identification of IL9R pseudogenes at 9qter, 10pter, 16pter, and 18pter.";
RL   Genomics 29:371-382(1995).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=10655549; DOI=10.1093/hmg/9.3.395;
RA   Ciccodicola A., D'Esposito M., Esposito T., Gianfrancesco F.,
RA   Migliaccio C., Miano M.G., Matarazzo M.R., Vacca M., Franze A.,
RA   Cuccurese M., Cocchia M., Curci A., Terracciano A., Torino A., Cocchia S.,
RA   Mercadante G., Pannone E., Archidiacono N., Rocchi M., Schlessinger D.,
RA   D'Urso M.;
RT   "Differentially regulated and evolved genes in the fully sequenced Xq/Yq
RT   pseudoautosomal region.";
RL   Hum. Mol. Genet. 9:395-401(2000).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND VARIANTS LYS-63; GLN-239 AND
RP   CYS-288.
RG   SeattleSNPs variation discovery resource;
RL   Submitted (DEC-2001) to the EMBL/GenBank/DDBJ databases.
RN   [5]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15772651; DOI=10.1038/nature03440;
RA   Ross M.T., Grafham D.V., Coffey A.J., Scherer S., McLay K., Muzny D.,
RA   Platzer M., Howell G.R., Burrows C., Bird C.P., Frankish A., Lovell F.L.,
RA   Howe K.L., Ashurst J.L., Fulton R.S., Sudbrak R., Wen G., Jones M.C.,
RA   Hurles M.E., Andrews T.D., Scott C.E., Searle S., Ramser J., Whittaker A.,
RA   Deadman R., Carter N.P., Hunt S.E., Chen R., Cree A., Gunaratne P.,
RA   Havlak P., Hodgson A., Metzker M.L., Richards S., Scott G., Steffen D.,
RA   Sodergren E., Wheeler D.A., Worley K.C., Ainscough R., Ambrose K.D.,
RA   Ansari-Lari M.A., Aradhya S., Ashwell R.I., Babbage A.K., Bagguley C.L.,
RA   Ballabio A., Banerjee R., Barker G.E., Barlow K.F., Barrett I.P.,
RA   Bates K.N., Beare D.M., Beasley H., Beasley O., Beck A., Bethel G.,
RA   Blechschmidt K., Brady N., Bray-Allen S., Bridgeman A.M., Brown A.J.,
RA   Brown M.J., Bonnin D., Bruford E.A., Buhay C., Burch P., Burford D.,
RA   Burgess J., Burrill W., Burton J., Bye J.M., Carder C., Carrel L.,
RA   Chako J., Chapman J.C., Chavez D., Chen E., Chen G., Chen Y., Chen Z.,
RA   Chinault C., Ciccodicola A., Clark S.Y., Clarke G., Clee C.M., Clegg S.,
RA   Clerc-Blankenburg K., Clifford K., Cobley V., Cole C.G., Conquer J.S.,
RA   Corby N., Connor R.E., David R., Davies J., Davis C., Davis J., Delgado O.,
RA   Deshazo D., Dhami P., Ding Y., Dinh H., Dodsworth S., Draper H.,
RA   Dugan-Rocha S., Dunham A., Dunn M., Durbin K.J., Dutta I., Eades T.,
RA   Ellwood M., Emery-Cohen A., Errington H., Evans K.L., Faulkner L.,
RA   Francis F., Frankland J., Fraser A.E., Galgoczy P., Gilbert J., Gill R.,
RA   Gloeckner G., Gregory S.G., Gribble S., Griffiths C., Grocock R., Gu Y.,
RA   Gwilliam R., Hamilton C., Hart E.A., Hawes A., Heath P.D., Heitmann K.,
RA   Hennig S., Hernandez J., Hinzmann B., Ho S., Hoffs M., Howden P.J.,
RA   Huckle E.J., Hume J., Hunt P.J., Hunt A.R., Isherwood J., Jacob L.,
RA   Johnson D., Jones S., de Jong P.J., Joseph S.S., Keenan S., Kelly S.,
RA   Kershaw J.K., Khan Z., Kioschis P., Klages S., Knights A.J., Kosiura A.,
RA   Kovar-Smith C., Laird G.K., Langford C., Lawlor S., Leversha M., Lewis L.,
RA   Liu W., Lloyd C., Lloyd D.M., Loulseged H., Loveland J.E., Lovell J.D.,
RA   Lozado R., Lu J., Lyne R., Ma J., Maheshwari M., Matthews L.H.,
RA   McDowall J., McLaren S., McMurray A., Meidl P., Meitinger T., Milne S.,
RA   Miner G., Mistry S.L., Morgan M., Morris S., Mueller I., Mullikin J.C.,
RA   Nguyen N., Nordsiek G., Nyakatura G., O'dell C.N., Okwuonu G., Palmer S.,
RA   Pandian R., Parker D., Parrish J., Pasternak S., Patel D., Pearce A.V.,
RA   Pearson D.M., Pelan S.E., Perez L., Porter K.M., Ramsey Y., Reichwald K.,
RA   Rhodes S., Ridler K.A., Schlessinger D., Schueler M.G., Sehra H.K.,
RA   Shaw-Smith C., Shen H., Sheridan E.M., Shownkeen R., Skuce C.D.,
RA   Smith M.L., Sotheran E.C., Steingruber H.E., Steward C.A., Storey R.,
RA   Swann R.M., Swarbreck D., Tabor P.E., Taudien S., Taylor T., Teague B.,
RA   Thomas K., Thorpe A., Timms K., Tracey A., Trevanion S., Tromans A.C.,
RA   d'Urso M., Verduzco D., Villasana D., Waldron L., Wall M., Wang Q.,
RA   Warren J., Warry G.L., Wei X., West A., Whitehead S.L., Whiteley M.N.,
RA   Wilkinson J.E., Willey D.L., Williams G., Williams L., Williamson A.,
RA   Williamson H., Wilming L., Woodmansey R.L., Wray P.W., Yen J., Zhang J.,
RA   Zhou J., Zoghbi H., Zorilla S., Buck D., Reinhardt R., Poustka A.,
RA   Rosenthal A., Lehrach H., Meindl A., Minx P.J., Hillier L.W., Willard H.F.,
RA   Wilson R.K., Waterston R.H., Rice C.M., Vaudin M., Coulson A., Nelson D.L.,
RA   Weinstock G., Sulston J.E., Durbin R.M., Hubbard T., Gibbs R.A., Beck S.,
RA   Rogers J., Bentley D.R.;
RT   "The DNA sequence of the human X chromosome.";
RL   Nature 434:325-337(2005).
RN   [6]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M.,
RA   Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J.,
RA   Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S.,
RA   Turner R., Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H.,
RA   Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K.,
RA   Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D.,
RA   Hunkapiller M.W., Myers E.W., Venter J.C.;
RL   Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
RN   [7]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 22-33, PARTIAL NUCLEOTIDE SEQUENCE
RP   [MRNA] (ISOFORM 2), AND VARIANT ARG-331.
RX   PubMed=8193355;
RA   Chang M.S., Engel G., Benedict C., Basu R., McNinch J.;
RT   "Isolation and characterization of the human interleukin-9 receptor gene.";
RL   Blood 83:3199-3205(1994).
CC   -!- FUNCTION: Plays an important role in the immune response against
CC       parasites by acting as a receptor of IL9.
CC       {ECO:0000250|UniProtKB:Q01114}.
CC   -!- SUBUNIT: Interacts with IL9. {ECO:0000250|UniProtKB:Q01114}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Single-pass type I membrane
CC       protein. Secreted.
CC   -!- ALTERNATIVE PRODUCTS:
CC       Event=Alternative splicing; Named isoforms=3;
CC       Name=1;
CC         IsoId=Q01113-1; Sequence=Displayed;
CC       Name=2;
CC         IsoId=Q01113-2; Sequence=VSP_039025;
CC       Name=3;
CC         IsoId=Q01113-3; Sequence=VSP_046207, VSP_046208, VSP_046209,
CC                                  VSP_046210;
CC   -!- DOMAIN: The WSXWS motif appears to be necessary for proper protein
CC       folding and thereby efficient intracellular transport and cell-surface
CC       receptor binding.
CC   -!- DOMAIN: The box 1 motif is required for JAK interaction and/or
CC       activation.
CC   -!- MISCELLANEOUS: The gene coding for this protein is located in the
CC       pseudoautosomal region 2 (PAR2) of X and Y chromosomes.
CC   -!- SIMILARITY: Belongs to the type I cytokine receptor family. Type 4
CC       subfamily. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAB30844.2; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
CC   -!- WEB RESOURCE: Name=SeattleSNPs;
CC       URL="http://pga.gs.washington.edu/data/il9r/";
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DR   EMBL; M84747; AAA58679.1; -; mRNA.
DR   EMBL; L39064; AAC29513.1; -; Genomic_DNA.
DR   EMBL; AJ271736; CAB96817.1; -; Genomic_DNA.
DR   EMBL; AY071830; AAL55435.1; -; Genomic_DNA.
DR   EMBL; CH471247; EAW55884.1; -; Genomic_DNA.
DR   EMBL; S71404; AAB30844.2; ALT_INIT; mRNA.
DR   EMBL; S71420; AAD14081.1; -; Genomic_DNA.
DR   CCDS; CCDS14771.4; -. [Q01113-1]
DR   CCDS; CCDS59180.1; -. [Q01113-3]
DR   PIR; B45268; B45268.
DR   RefSeq; NP_002177.2; NM_002186.2. [Q01113-1]
DR   RefSeq; NP_789743.2; NM_176786.1. [Q01113-3]
DR   RefSeq; XP_011529456.1; XM_011531154.2.
DR   RefSeq; XP_011543951.1; XM_011545649.2.
DR   RefSeq; XP_016884986.1; XM_017029497.1.
DR   RefSeq; XP_016884987.1; XM_017029498.1.
DR   RefSeq; XP_016884988.1; XM_017029499.1.
DR   RefSeq; XP_016885535.1; XM_017030046.1.
DR   RefSeq; XP_016885536.1; XM_017030047.1.
DR   RefSeq; XP_016885537.1; XM_017030048.1.
DR   PDB; 7OX5; X-ray; 3.09 A; A/C/E/G/I/K/M/O=40-261.
DR   PDBsum; 7OX5; -.
DR   AlphaFoldDB; Q01113; -.
DR   SMR; Q01113; -.
DR   BioGRID; 109795; 28.
DR   DIP; DIP-3156N; -.
DR   ELM; Q01113; -.
DR   IntAct; Q01113; 12.
DR   MINT; Q01113; -.
DR   STRING; 9606.ENSP00000244174; -.
DR   GlyCosmos; Q01113; 2 sites, No reported glycans.
DR   GlyGen; Q01113; 2 sites.
DR   iPTMnet; Q01113; -.
DR   PhosphoSitePlus; Q01113; -.
DR   BioMuta; IL9R; -.
DR   DMDM; 116242526; -.
DR   MassIVE; Q01113; -.
DR   PaxDb; 9606-ENSP00000244174; -.
DR   PeptideAtlas; Q01113; -.
DR   ProteomicsDB; 57919; -. [Q01113-1]
DR   ProteomicsDB; 57920; -. [Q01113-2]
DR   ProteomicsDB; 7556; -.
DR   Antibodypedia; 4187; 480 antibodies from 33 providers.
DR   DNASU; 3581; -.
DR   Ensembl; ENST00000244174.11; ENSP00000244174.5; ENSG00000124334.18. [Q01113-1]
DR   Ensembl; ENST00000369423.7; ENSP00000358431.2; ENSG00000124334.18. [Q01113-3]
DR   Ensembl; ENST00000711286.1; ENSP00000518617.1; ENSG00000292373.1. [Q01113-1]
DR   Ensembl; ENST00000711287.1; ENSP00000518616.1; ENSG00000292373.1. [Q01113-3]
DR   GeneID; 3581; -.
DR   KEGG; hsa:3581; -.
DR   MANE-Select; ENST00000244174.11; ENSP00000244174.5; NM_002186.3; NP_002177.2.
DR   UCSC; uc004fnu.2; human. [Q01113-1]
DR   AGR; HGNC:6030; -.
DR   CTD; 3581; -.
DR   DisGeNET; 3581; -.
DR   GeneCards; IL9R; -.
DR   HGNC; HGNC:6030; IL9R.
DR   HPA; ENSG00000124334; Tissue enhanced (lymphoid tissue, urinary bladder).
DR   MIM; 300007; gene.
DR   neXtProt; NX_Q01113; -.
DR   OpenTargets; ENSG00000124334; -.
DR   PharmGKB; PA29846; -.
DR   VEuPathDB; HostDB:ENSG00000124334; -.
DR   eggNOG; ENOG502SB39; Eukaryota.
DR   GeneTree; ENSGT00510000049125; -.
DR   HOGENOM; CLU_614777_0_0_1; -.
DR   InParanoid; Q01113; -.
DR   OMA; VKRTFYQ; -.
DR   OrthoDB; 5361898at2759; -.
DR   PhylomeDB; Q01113; -.
DR   TreeFam; TF337874; -.
DR   PathwayCommons; Q01113; -.
DR   Reactome; R-HSA-8985947; Interleukin-9 signaling.
DR   SignaLink; Q01113; -.
DR   SIGNOR; Q01113; -.
DR   BioGRID-ORCS; 3581; 62 hits in 611 CRISPR screens.
DR   GeneWiki; Interleukin-9_receptor; -.
DR   GenomeRNAi; 3581; -.
DR   Pharos; Q01113; Tbio.
DR   PRO; PR:Q01113; -.
DR   Proteomes; UP000005640; Chromosome X.
DR   Proteomes; UP000005640; Chromosome Y.
DR   RNAct; Q01113; Protein.
DR   Bgee; ENSG00000124334; Expressed in primordial germ cell in gonad and 94 other cell types or tissues.
DR   GO; GO:0009897; C:external side of plasma membrane; IBA:GO_Central.
DR   GO; GO:0005615; C:extracellular space; TAS:ProtInc.
DR   GO; GO:0005886; C:plasma membrane; IDA:UniProt.
DR   GO; GO:0019983; F:interleukin-9 binding; IBA:GO_Central.
DR   GO; GO:0004919; F:interleukin-9 receptor activity; IDA:UniProt.
DR   GO; GO:0019221; P:cytokine-mediated signaling pathway; IBA:GO_Central.
DR   GO; GO:0016064; P:immunoglobulin mediated immune response; IBA:GO_Central.
DR   GO; GO:0038113; P:interleukin-9-mediated signaling pathway; IDA:UniProt.
DR   GO; GO:0042127; P:regulation of cell population proliferation; TAS:GO_Central.
DR   GO; GO:0007165; P:signal transduction; TAS:ProtInc.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR   InterPro; IPR003961; FN3_dom.
DR   InterPro; IPR036116; FN3_sf.
DR   InterPro; IPR003531; Hempt_rcpt_S_F1_CS.
DR   InterPro; IPR013783; Ig-like_fold.
DR   PANTHER; PTHR23037; CYTOKINE RECEPTOR; 1.
DR   PANTHER; PTHR23037:SF29; INTERLEUKIN-9 RECEPTOR; 1.
DR   SUPFAM; SSF49265; Fibronectin type III; 1.
DR   PROSITE; PS50853; FN3; 1.
DR   PROSITE; PS01355; HEMATOPO_REC_S_F1; 1.
DR   Genevisible; Q01113; HS.
PE   1: Evidence at protein level;
KW   3D-structure; Alternative splicing; Cell membrane; Glycoprotein; Membrane;
KW   Receptor; Reference proteome; Secreted; Signal; Transmembrane;
KW   Transmembrane helix.
FT   SIGNAL          1..40
FT                   /evidence="ECO:0000255"
FT   CHAIN           41..521
FT                   /note="Interleukin-9 receptor"
FT                   /id="PRO_0000010911"
FT   TOPO_DOM        41..270
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        271..291
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        292..521
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          149..259
FT                   /note="Fibronectin type-III"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00316"
FT   REGION          413..439
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOTIF           245..249
FT                   /note="WSXWS motif"
FT   MOTIF           301..309
FT                   /note="Box 1 motif"
FT   COMPBIAS        422..439
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CARBOHYD        117
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        156
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   VAR_SEQ         1..21
FT                   /note="Missing (in isoform 2)"
FT                   /evidence="ECO:0000305"
FT                   /id="VSP_039025"
FT   VAR_SEQ         1..9
FT                   /note="MGLGRCIWE -> MPQTCDGTGQMHLGSNCCKNGQTLLQRTCHGVSCCGWWF
FT                   QAARSILGKGPSAQSLA (in isoform 3)"
FT                   /evidence="ECO:0000305"
FT                   /id="VSP_046207"
FT   VAR_SEQ         85..154
FT                   /note="SNQAPGGTHKCILRGSECTVVLPPEAVLVPSDNFTITFHHCMSGREQVSLVD
FT                   PEYLPRRHVKLDPPSDLQ -> RLLAAHISASCGAVSAPSCCHLRQCSCHLTISPSLST
FT                   TACLGGSRSAWWTRSTCPGDT (in isoform 3)"
FT                   /evidence="ECO:0000305"
FT                   /id="VSP_046208"
FT   VAR_SEQ         297..307
FT                   /note="VKRIFYQNVPS -> LGWGPTGPVCC (in isoform 3)"
FT                   /evidence="ECO:0000305"
FT                   /id="VSP_046209"
FT   VAR_SEQ         308..521
FT                   /note="Missing (in isoform 3)"
FT                   /evidence="ECO:0000305"
FT                   /id="VSP_046210"
FT   VARIANT         63
FT                   /note="R -> K (in dbSNP:rs3093495)"
FT                   /evidence="ECO:0000269|Ref.4"
FT                   /id="VAR_038784"
FT   VARIANT         239
FT                   /note="E -> Q (in dbSNP:rs6522)"
FT                   /evidence="ECO:0000269|Ref.4"
FT                   /id="VAR_014804"
FT   VARIANT         288
FT                   /note="Y -> C (in dbSNP:rs149119910)"
FT                   /evidence="ECO:0000269|Ref.4"
FT                   /id="VAR_033920"
FT   VARIANT         331
FT                   /note="G -> R (in dbSNP:rs2230001)"
FT                   /evidence="ECO:0000269|PubMed:1376929,
FT                   ECO:0000269|PubMed:8193355"
FT                   /id="VAR_055348"
FT   VARIANT         365
FT                   /note="R -> H (in dbSNP:rs2228650)"
FT                   /id="VAR_055349"
FT   CONFLICT        438
FT                   /note="S -> SS (in Ref. 1; AAA58679 and 4; AAL55435)"
FT                   /evidence="ECO:0000305"
FT   HELIX           51..53
FT                   /evidence="ECO:0007829|PDB:7OX5"
FT   STRAND          54..58
FT                   /evidence="ECO:0007829|PDB:7OX5"
FT   STRAND          60..69
FT                   /evidence="ECO:0007829|PDB:7OX5"
FT   TURN            71..74
FT                   /evidence="ECO:0007829|PDB:7OX5"
FT   STRAND          75..77
FT                   /evidence="ECO:0007829|PDB:7OX5"
FT   STRAND          80..87
FT                   /evidence="ECO:0007829|PDB:7OX5"
FT   STRAND          92..96
FT                   /evidence="ECO:0007829|PDB:7OX5"
FT   STRAND          99..105
FT                   /evidence="ECO:0007829|PDB:7OX5"
FT   HELIX           108..110
FT                   /evidence="ECO:0007829|PDB:7OX5"
FT   STRAND          118..125
FT                   /evidence="ECO:0007829|PDB:7OX5"
FT   STRAND          131..139
FT                   /evidence="ECO:0007829|PDB:7OX5"
FT   HELIX           141..143
FT                   /evidence="ECO:0007829|PDB:7OX5"
FT   STRAND          151..158
FT                   /evidence="ECO:0007829|PDB:7OX5"
FT   STRAND          161..167
FT                   /evidence="ECO:0007829|PDB:7OX5"
FT   HELIX           170..178
FT                   /evidence="ECO:0007829|PDB:7OX5"
FT   STRAND          179..187
FT                   /evidence="ECO:0007829|PDB:7OX5"
FT   HELIX           192..194
FT                   /evidence="ECO:0007829|PDB:7OX5"
FT   STRAND          196..203
FT                   /evidence="ECO:0007829|PDB:7OX5"
FT   STRAND          205..209
FT                   /evidence="ECO:0007829|PDB:7OX5"
FT   STRAND          218..228
FT                   /evidence="ECO:0007829|PDB:7OX5"
FT   HELIX           237..239
FT                   /evidence="ECO:0007829|PDB:7OX5"
FT   STRAND          252..255
FT                   /evidence="ECO:0007829|PDB:7OX5"
SQ   SEQUENCE   521 AA;  57147 MW;  07C40436466173F3 CRC64;
     MGLGRCIWEG WTLESEALRR DMGTWLLACI CICTCVCLGV SVTGEGQGPR SRTFTCLTNN
     ILRIDCHWSA PELGQGSSPW LLFTSNQAPG GTHKCILRGS ECTVVLPPEA VLVPSDNFTI
     TFHHCMSGRE QVSLVDPEYL PRRHVKLDPP SDLQSNISSG HCILTWSISP ALEPMTTLLS
     YELAFKKQEE AWEQAQHRDH IVGVTWLILE AFELDPGFIH EARLRVQMAT LEDDVVEEER
     YTGQWSEWSQ PVCFQAPQRQ GPLIPPWGWP GNTLVAVSIF LLLTGPTYLL FKLSPRVKRI
     FYQNVPSPAM FFQPLYSVHN GNFQTWMGAH GAGVLLSQDC AGTPQGALEP CVQEATALLT
     CGPARPWKSV ALEEEQEGPG TRLPGNLSSE DVLPAGCTEW RVQTLAYLPQ EDWAPTSLTR
     PAPPDSEGSR SSSSSSSSNN NNYCALGCYG GWHLSALPGN TQSSGPIPAL ACGLSCDHQG
     LETQQGVAWV LAGHCQRPGL HEDLQGMLLP SVLSKARSWT F
//