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Q01103 (PCAI_PSEPU) Reviewed, UniProtKB/Swiss-Prot

Last modified October 16, 2013. Version 61. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
3-oxoadipate CoA-transferase subunit A

EC=2.8.3.6
Alternative name(s):
Beta-ketoadipate:succinyl-CoA transferase subunit A
Gene names
Name:pcaI
OrganismPseudomonas putida (Arthrobacter siderocapsulatus)
Taxonomic identifier303 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas

Protein attributes

Sequence length231 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Catalytic activity

Succinyl-CoA + 3-oxoadipate = succinate + 3-oxoadipyl-CoA.

Pathway

Aromatic compound metabolism; beta-ketoadipate pathway; acetyl-CoA and succinyl-CoA from 3-oxoadipate: step 1/2.

Subunit structure

Heterodimer.

Sequence similarities

Belongs to the 3-oxoacid CoA-transferase subunit A family.

Ontologies

Keywords
   Biological processAromatic hydrocarbons catabolism
   Molecular functionTransferase
   Technical termDirect protein sequencing
Gene Ontology (GO)
   Biological_processbeta-ketoadipate pathway

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Molecular_function3-oxoadipate CoA-transferase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 2312313-oxoadipate CoA-transferase subunit A
PRO_0000157907

Regions

Region25 – 317CoA-binding Potential

Sequences

Sequence LengthMass (Da)Tools
Q01103 [UniParc].

Last modified November 1, 1995. Version 2.
Checksum: B5071507AC6A442C

FASTA23124,234
        10         20         30         40         50         60 
MINKTYESIA SAVEGITDGS TIMVGGFGTA GMPSELIDGL IATGARDLTI ISNNAGNGEI 

        70         80         90        100        110        120 
GLAALLMAGS VRKVVCSFPR QSDSYVFDEL YRAGKIELEV VPQGNLAERI AAAGSGIGAF 

       130        140        150        160        170        180 
FSPTGYGTLL AEGKETREID GRMYVLEMPL HADFALIKAH KGDRWGNLTY RKAARNFGPI 

       190        200        210        220        230 
MAMAAKTAIA QVDQVVELGE LDPEHIITPG IFVQRVVAVS GAAASSIAKA I 

« Hide

References

[1]"Characterization of the genes encoding beta-ketoadipate: succinyl-coenzyme A transferase in Pseudomonas putida."
Parales R.E., Harwood C.S.
J. Bacteriol. 174:4657-4666(1992) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: PRS2000.
[2]"Evolutionarily homologous alpha 2 beta 2 oligomeric structures in beta-ketoadipate succinyl-CoA transferases from Acinetobacter calcoaceticus and Pseudomonas putida."
Yeh W.-K., Ornston L.N.
J. Biol. Chem. 256:1565-1569(1981) [PubMed] [Europe PMC] [Abstract]
Cited for: PROTEIN SEQUENCE OF 1-6.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
M88763 Genomic DNA. Translation: AAA25922.1.
PIRA42985.

3D structure databases

ProteinModelPortalQ01103.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Enzyme and pathway databases

BioCycMetaCyc:MONOMER-3190.
UniPathwayUPA00157; UER00262.

Family and domain databases

InterProIPR012792. 3-oxoacid_CoA-transf_A.
IPR004165. CoA_trans_fam_I.
IPR004163. CoA_transf_BS.
[Graphical view]
PANTHERPTHR13707. PTHR13707. 1 hit.
PfamPF01144. CoA_trans. 1 hit.
[Graphical view]
SMARTSM00882. CoA_trans. 1 hit.
[Graphical view]
TIGRFAMsTIGR02429. pcaI_scoA_fam. 1 hit.
PROSITEPS01273. COA_TRANSF_1. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePCAI_PSEPU
AccessionPrimary (citable) accession number: Q01103
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: November 1, 1995
Last modified: October 16, 2013
This is version 61 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways