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Protein

Acetolactate synthase

Gene

OT_ostta16g02080

Organism
Ostreococcus tauri
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Catalytic activityi

2 pyruvate = 2-acetolactate + CO2.UniRule annotation

Cofactori

Protein has several cofactor binding sites:
  • Mg2+UniRule annotationNote: Binds 1 Mg2+ ion per subunit.UniRule annotation
  • thiamine diphosphateUniRule annotationNote: Binds 1 thiamine pyrophosphate per subunit.UniRule annotation

Pathwayi: L-isoleucine biosynthesis

This protein is involved in step 1 of the subpathway that synthesizes L-isoleucine from 2-oxobutanoate.UniRule annotation
Proteins known to be involved in the 4 steps of the subpathway in this organism are:
  1. Acetolactate synthase (OT_ostta16g02080), Acetolactate synthase (BE221DRAFT_12990)
  2. no protein annotated in this organism
  3. no protein annotated in this organism
  4. no protein annotated in this organism
This subpathway is part of the pathway L-isoleucine biosynthesis, which is itself part of Amino-acid biosynthesis.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes L-isoleucine from 2-oxobutanoate, the pathway L-isoleucine biosynthesis and in Amino-acid biosynthesis.

Pathwayi: L-valine biosynthesis

This protein is involved in step 1 of the subpathway that synthesizes L-valine from pyruvate.UniRule annotation
Proteins known to be involved in the 4 steps of the subpathway in this organism are:
  1. Acetolactate synthase (OT_ostta16g02080), Acetolactate synthase (BE221DRAFT_12990)
  2. no protein annotated in this organism
  3. no protein annotated in this organism
  4. no protein annotated in this organism
This subpathway is part of the pathway L-valine biosynthesis, which is itself part of Amino-acid biosynthesis.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes L-valine from pyruvate, the pathway L-valine biosynthesis and in Amino-acid biosynthesis.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionTransferaseUniRule annotation
Biological processAmino-acid biosynthesis, Branched-chain amino acid biosynthesisUniRule annotation
LigandMagnesiumUniRule annotation, Metal-bindingUniRule annotation, Thiamine pyrophosphateUniRule annotation

Enzyme and pathway databases

UniPathwayiUPA00047; UER00055
UPA00049; UER00059

Names & Taxonomyi

Protein namesi
Recommended name:
Acetolactate synthaseUniRule annotation (EC:2.2.1.6UniRule annotation)
Gene namesi
ORF Names:OT_ostta16g02080Imported
OrganismiOstreococcus tauriImported
Taxonomic identifieri70448 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeChlorophytaprasinophytesMamiellophyceaeMamiellalesBathycoccaceaeOstreococcus
Proteomesi
  • UP000009170 Componenti: Chromosome 16

Interactioni

Protein-protein interaction databases

STRINGi70448.Q00U23

Structurei

3D structure databases

ProteinModelPortaliQ00U23
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini92 – 256TPP_enzyme_NInterPro annotationAdd BLAST165
Domaini284 – 417TPP_enzyme_MInterPro annotationAdd BLAST134
Domaini479 – 641TPP_enzyme_CInterPro annotationAdd BLAST163

Sequence similaritiesi

Belongs to the TPP enzyme family.UniRule annotation

Phylogenomic databases

eggNOGiKOG4166 Eukaryota
COG0028 LUCA
HOGENOMiHOG000258448
InParanoidiQ00U23
KOiK01652
OMAiQGMVRQW

Family and domain databases

InterProiView protein in InterPro
IPR012846 Acetolactate_synth_lsu
IPR029035 DHS-like_NAD/FAD-binding_dom
IPR029061 THDP-binding
IPR012000 Thiamin_PyroP_enz_cen_dom
IPR012001 Thiamin_PyroP_enz_TPP-bd_dom
IPR000399 TPP-bd_CS
IPR011766 TPP_enzyme-bd_C
PfamiView protein in Pfam
PF02775 TPP_enzyme_C, 1 hit
PF00205 TPP_enzyme_M, 1 hit
PF02776 TPP_enzyme_N, 1 hit
SUPFAMiSSF52467 SSF52467, 1 hit
SSF52518 SSF52518, 2 hits
TIGRFAMsiTIGR00118 acolac_lg, 1 hit
PROSITEiView protein in PROSITE
PS00187 TPP_ENZYMES, 1 hit

Sequencei

Sequence statusi: Complete.

Q00U23-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHANARAQRT PTTALSVQNA RVSRRAAIRA RSQIRRVLSL KSPAVREPGA
60 70 80 90 100
SEYVDPSQFT ELELTTSQMT AYASRRPIGH FQSRFADDEP RKGADILVEA
110 120 130 140 150
LEREGVDCVF AYPGGASMEI HQSLTKSVTG IRNVLCRHEQ GEVFAAEGYA
160 170 180 190 200
KSTGKVGVCI ATSGPGATNL VTGLADALLD SVPMVAITGQ VPRPMIGTDA
210 220 230 240 250
FQETPIVEIT RQITKHNYLV MNVEEIPRIV REAFFLASSG RPGPVLIDIP
260 270 280 290 300
KDVQQQLAVP YWEPKVSLHG YLSRLPGPPT NPQIQQVVDL IKKSKKPIVY
310 320 330 340 350
AGGGCLDASK ELVEFCRATG IPVTNTLMGL GTFPQSDDLS LSMLGMHGAV
360 370 380 390 400
YANYAIDSAD LLLAFGVRFD DRVTGKLAEF AKRAAIVHID IDPAELGKNK
410 420 430 440 450
KPFCSIFSNI KPALRSLNKL IALDAANLPD FSDWRAEIEV KRKEFPFPIP
460 470 480 490 500
KQQGDVIAPQ AAIELLCKLT EGKAIISTGV GQHQMWAAQH YKFDEPRNWL
510 520 530 540 550
SSGGLGSMGF GLPAAIGAQA ARPDELVIDI DGDGSFVMNI QELATLHAEE
560 570 580 590 600
LPVKCFILNN QYLGMVVQWE DRFYKANRGH TYLGSPNDDY QVSKEEAHIF
610 620 630 640 650
PDFVTISNGF RVPAERVTRM SELEGAIKRM IETPGPYLLD VMVPHVEHVL
660 670
PMVPGGGTFA DTIVTGDGRT PEEKDMKTL
Length:679
Mass (Da):74,211
Last modified:November 14, 2006 - v1
Checksum:i48CFA490D4655C0A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CAID01000016 Genomic DNA Translation: CAL58226.1
RefSeqiXP_003083677.1, XM_003083629.1

Genome annotation databases

GeneIDi9831116
KEGGiota:OT_ostta16g02080

Similar proteinsi

Entry informationi

Entry nameiQ00U23_OSTTA
AccessioniPrimary (citable) accession number: Q00U23
Entry historyiIntegrated into UniProtKB/TrEMBL: November 14, 2006
Last sequence update: November 14, 2006
Last modified: May 23, 2018
This is version 76 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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