Unreviewed, UniProtKB/TrEMBL Q00IN0 (Q00IN0_DROME)

Names and origin

Protein names

Submitted name:
    RhoGAP18B, isoform D EMBL ACL82950.1
Submitted name:
    RhoGAP18B-PD EMBL ABF50838.1

Gene names

Name:	RhoGAP18B FlyBase FBgn0030986 FlyBase FBgn0259169
ORF Names:	Dmel_CG42274 EMBL ACL82950.1

Organism

Drosophila melanogaster (Fruit fly) [Complete proteome] EMBL ABF50838.1

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	752 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Sequence similarities

Contains 1 Rho-GAP domain. Spearmint SPM000198

Ontologies

Keywords
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	signal transduction Inferred from electronic annotation. Source: InterPro
Cellular component	intracellular Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q00IN0-1 [UniParc]. Last modified November 14, 2006. Version 1. Checksum: 81865DF74584DBD0	FASTA	752	84,475
	10 20 30 40 50 60 MAAPKPNGEA ERPSTNSNNN TINCSSNNNN DNISNNNNNH HTVDNESGIN NNKNNDGNAN 70 80 90 100 110 120 CNVNEQQQQQ QQQPITQNCV IKVRRPAPKV PVRNPNTSLS NPRQIEEEQT KPNGGKKDNL 130 140 150 160 170 180 RGNSFAAENS SPEEQEEESI YQPIWQFKTI EPVDQEIIEA LPVEGEDEED EDEEDDDVDD 190 200 210 220 230 240 EEEDLGDYDE SLPSDADPDV MALQAAAVFA AGVRHKLSTS TLTKRSKMMM PTPLPSPTAS 250 260 270 280 290 300 MDHGAWETDM EFMYSRESKE EADETLSLGS TVTNSTATLG SISSTGSSVT GQPKDTPKDL 310 320 330 340 350 360 PADQQPSVVV HPILRNICIF YSQKDPKKYS AIFYDYHLSL VHQRFMTRIR RPAPPPPAQL 370 380 390 400 410 420 ATSNTTSLAP RSDDSGCSCE AEDSYNHQHN PTPAIPKPLK EEWERAVLAA GAVAGKRGVA 430 440 450 460 470 480 PRTGRKLRVR SNARLLLTDS VLAWRETLQD VNCCEDEEDM IVPVTDILRA QQIQEDNEVQ 490 500 510 520 530 540 QTQQSTILQR YKSVSIGNLL DLPGEDDKKS IKNRMRMKFA VNSNVFRINR SPKSEKKSRS 550 560 570 580 590 600 RRGQVNSLYL DEQKYPLFAA PLSALELNMT DHPNVPRFVV DVCAYIEQPE CIEQDGLYRA 610 620 630 640 650 660 SGNKVLVDEL RKKLTHVYDP RWLKTDDIHT LTSLHKQFFR ELTSPLITQE AYERLGRSLN 670 680 690 700 710 720 DDAAIERMSL AFDDMPEPNR STLRFLIRHL TRVAAASASN RMPSTNLAIV WGPCLLSANQ 730 740 750 IQLDIGRMNM LAKVLIENYD RIFHPDNERL VC

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Distinct behavioral responses to ethanol are regulated by alternate RhoGAP18B isoforms." Rothenfluh A., Threlkeld R.J., Bainton R.J., Tsai L.T., Lasek A.W., Heberlein U. Cell 127:199-211(2006) [PubMed: 17018286] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[2]	"Annotation of the Drosophila melanogaster euchromatic genome: a systematic review." Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P., Bettencourt B.R., Celniker S.E., de Grey A.D.N.J. , Drysdale R.A., Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E. Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002) [PubMed: 12537572] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.
[3]	"The genome sequence of Drosophila melanogaster." Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D. , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A., An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T., Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C. Science 287:2185-2195(2000) [PubMed: 10731132] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.

Cross-references

Sequence databases
EMBLGenBankDDBJ	DQ486142 mRNA. Translation: ABF50838.1. AE014298 Genomic DNA. Translation: ACL82950.1.
RefSeq	NP_001138220.1.
3D structure databases
ModBase	Search...
Proteomic databases
PRIDE	Q00IN0.
Genome annotation databases
Ensembl	FBgn0030986. Drosophila melanogaster. [Contig view]
GeneID	32898.
Organism-specific databases
FlyBase	FBgn0259169. RhoGAP18B.
Family and domain databases
InterPro	IPR000198. RhoGAP. [Graphical view]
Gene3D	G3DSA:1.10.555.10. RhoGAP. 1 hit.
Pfam	PF00620. RhoGAP. 1 hit. [Graphical view]
SMART	SM00324. RhoGAP. 1 hit. [Graphical view]
PROSITE	PS50238. RHOGAP. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q00IN0_DROME

Accession

Primary (citable) accession number: Q00IN0

Entry history

Integrated into UniProtKB/TrEMBL:	November 14, 2006
Last sequence update:	November 14, 2006
Last modified:	June 16, 2009
This is version 18 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)