Q00IM9 (Q00IM9_DROME) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
RhoGAP18B-PC EMBL ABF50839.1

Gene names

Name:

RhoGAP18B FlyBase FBgn0030986 FlyBase FBgn0259169 FlyBase FBgn0261461

Organism

Drosophila melanogaster (Fruit fly)

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	1317 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

Ontologies

Gene Ontology (GO)
Biological process	actin filament organization Inferred from mutant phenotype. Source: FlyBase signal transduction Inferred from electronic annotation. Source: InterPro
Cellular component	intracellular Inferred from electronic annotation. Source: InterPro
Molecular function	GTPase activator activity Inferred from direct assay Ref.1. Source: FlyBase
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q00IM9 [UniParc]. Last modified November 14, 2006. Version 1. Checksum: 9652395A642EDC9E	FASTA	1,317	147,365
	10 20 30 40 50 60 MPQQAKDIND NVGMEAHIYE NLPGLTSTPK GHLNAELRKY FPREAIYENL CRGCGYGVFA 70 80 90 100 110 120 AQGRYCHFCQ CIVSGGVVST PPPPPPPPLS TISGESSNIY ENICDLCRGI YSDNERCRCQ 130 140 150 160 170 180 RSETPAKAPA PSTPTTPPTP PTKVKSRSLL GYSKSSAATL TRLFGSLKQL NRSSSLQRRI 190 200 210 220 230 240 FPRTPTTGSS SAGSLEIIHN VDEVFRTQET FDLQRICELK LEQQQLKGSQ SDQHIYGRVR 250 260 270 280 290 300 EPEESQSHKR ERKRPRVSRI RLLQDESTSG SSSLYLNESI CQWMTSLRRQ VHHYDEGPWQ 310 320 330 340 350 360 QPKSVPARDP SSSAEESTVT LRRSTEESAK CADEQAKLVK DFKRKLQQKR AHNVEPEREQ 370 380 390 400 410 420 RRCAITANFV NDYLSALGEE KEAVQHQQVA AIEEHVAVVA IAIQPQVSVS LLRLMQSLAL 430 440 450 460 470 480 SASLHVSVRG FLTAYDKSFS LWLWHQQQQQ RQQPPINGYR RRRARDSVVG VVGDWRRRLP 490 500 510 520 530 540 LFAFSFAGGN DRSVASASVS VSPAISESVD VCAAAASRRR ANRSTRRRGT AIVREEGVCG 550 560 570 580 590 600 GESSTSSNNS KKNNNNNSNN NSGALMAAPK PNGEAERPST NSNNNTINCS SNNNNDNISN 610 620 630 640 650 660 NNNNHHTVDN ESGINNNKNN DGNANCNVNE QQQQQQQQPI TQNCVIKVRR PAPKVPVRNP 670 680 690 700 710 720 NTSLSNPRQI EEEQTKPNGG KKDNLRGNSF AAENSSPEEQ EEESIYQPIW QFKTIEPVDQ 730 740 750 760 770 780 EIIEALPVEG EDEEDEDEED DDVEDEEEDL GDYDESLPSD ADPDVMALQA AAVFAAGVRH 790 800 810 820 830 840 KLSTSTLTKR SKMMMPTPLP SPTASMDHGA WETDMEFMYS RESKEEADET LSLGSTVTNS 850 860 870 880 890 900 TATLGSISST GSSVTGQPKD TPKDLPADQQ PSVVVHPILR NICIFYSQKD PKKYSAIFYD 910 920 930 940 950 960 YHLSLVHQRF MTRIRRPAPP PPAQLATSNT TSLAPRSDDS GCSCEAEDSY NHQHNPTPAI 970 980 990 1000 1010 1020 PKPLKEEWER AVLAAGAVAG KRGVAPRTGR KLRVRSNARL LLTDSVLAWR ETLQDVNCCE 1030 1040 1050 1060 1070 1080 DEEDMIVPVT DILRAQQIQE DNEVQQTQQS TILQRYKSVS IGNLLDLPGE DDKKSIKNRM 1090 1100 1110 1120 1130 1140 RMKFAVNSNV FRINRSPKSE KKSRSRRGQV NSLYLDEQKY PLFAAPLSAL ELNMTDHPNV 1150 1160 1170 1180 1190 1200 PRFVVDVCAY IEQPECIEQD GLYRASGNKV LVDELRKKLT HVYDPRWLKT DDIHTLTSLH 1210 1220 1230 1240 1250 1260 KQFFRELTSP LITQEAYERL GRSLNDDAAI ERMSLAFDDM PEPNRSTLRF LIRHLTRVAA 1270 1280 1290 1300 1310 ASASNRMPST NLAIVWGPCL LSANQIQLDI GRMNMLAKVL IENYDRIFHP DNERLVC

References

[1]	"Distinct behavioral responses to ethanol are regulated by alternate RhoGAP18B isoforms." Rothenfluh A., Threlkeld R.J., Bainton R.J., Tsai L.T., Lasek A.W., Heberlein U. Cell 127:199-211(2006) [PubMed: 17018286] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	DQ486143 mRNA. Translation: ABF50839.1.
3D structure databases
ProteinModelPortal	Q00IM9.
SMR	Q00IM9. Positions 1123-1308.
ModBase	Search...
Proteomic databases
PRIDE	Q00IM9.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
UCSC	CG42274-RB. d. melanogaster.
Organism-specific databases
FlyBase	FBgn0261461. RhoGAP18B.
Phylogenomic databases
InParanoid	Q00IM9.
OrthoDB	EOG4CNP64.
Gene expression databases
ArrayExpress	Q00IM9.
Bgee	Q00IM9.
Family and domain databases
InterPro	IPR008936. Rho_GTPase_activation_prot. IPR000198. RhoGAP_dom. [Graphical view]
Gene3D	G3DSA:1.10.555.10. RhoGAP. 1 hit.
Pfam	PF00620. RhoGAP. 1 hit. [Graphical view]
SMART	SM00324. RhoGAP. 1 hit. [Graphical view]
SUPFAM	SSF48350. Rho_GAP. 1 hit.
PROSITE	PS50238. RHOGAP. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q00IM9_DROME

Accession

Primary (citable) accession number: Q00IM9

Entry history

Integrated into UniProtKB/TrEMBL:	November 14, 2006
Last sequence update:	November 14, 2006
Last modified:	November 16, 2011
This is version 36 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)