Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Sucrose synthase 2

Gene

SUS2

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Sucrose-cleaving enzyme that provides UDP-glucose and fructose for various metabolic pathways. Modulates metabolic homeostasis and directs carbon towards starch synthesis in developing seeds.2 Publications

Catalytic activityi

NDP-glucose + D-fructose = NDP + sucrose.

GO - Molecular functioni

  • sucrose synthase activity Source: TAIR

GO - Biological processi

  • response to hypoxia Source: TAIR
  • seed maturation Source: TAIR
  • starch metabolic process Source: TAIR
  • sucrose metabolic process Source: TAIR

Keywordsi

Molecular functionGlycosyltransferase, Transferase
Biological processStress response

Enzyme and pathway databases

BRENDAi2.4.1.13 399

Protein family/group databases

CAZyiGT4 Glycosyltransferase Family 4

Names & Taxonomyi

Protein namesi
Recommended name:
Sucrose synthase 2 (EC:2.4.1.13)
Short name:
AtSUS2
Alternative name(s):
Sucrose-UDP glucosyltransferase 2
Gene namesi
Name:SUS2
Synonyms:SSA
Ordered Locus Names:At5g49190
ORF Names:K21P3.6
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 5

Organism-specific databases

AraportiAT5G49190
TAIRilocus:2155894 AT5G49190

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Membrane, Plastid

Pathology & Biotechi

Disruption phenotypei

No visible phenotype. Diminution of the starch content of developing seeds and increased lipid accumulation early during seed development.2 Publications

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002046451 – 807Sucrose synthase 2Add BLAST807

Proteomic databases

PaxDbiQ00917
PRIDEiQ00917

Expressioni

Tissue specificityi

Detected in the whole plant but at lower levels. Predominantly expressed in developing siliques. Also detected in the root tip. Detected in the embryo, endosperm and seed coat (at the protein level).4 Publications

Developmental stagei

Specifically and highly expressed during seed maturation at 12 days after flowering (at the protein level).2 Publications

Inductioni

By anaerobic stress and by glucose. Positively regulated by the NF-Y/HAP transcription factor complex at least composed of NFYB9/LEC1 or NFYB6/L1L and NFYC2/HAP5B in association with DPBF2/BZIP67. Positively regulated by LEC2.3 Publications

Gene expression databases

ExpressionAtlasiQ00917 baseline and differential
GenevisibleiQ00917 AT

Interactioni

Protein-protein interaction databases

BioGridi20224, 1 interactor
STRINGi3702.AT5G49190.1

Structurei

3D structure databases

ProteinModelPortaliQ00917
SMRiQ00917
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni274 – 752GT-B glycosyltransferaseBy similarityAdd BLAST479

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG0853 Eukaryota
COG0438 LUCA
HOGENOMiHOG000240125
InParanoidiQ00917
KOiK00695
OMAiECYAKNS
OrthoDBiEOG0936023J

Family and domain databases

InterProiView protein in InterPro
IPR001296 Glyco_trans_1
IPR000368 Sucrose_synth
IPR012820 Sucrose_synthase_pln/cyn
PfamiView protein in Pfam
PF00534 Glycos_transf_1, 1 hit
PF00862 Sucrose_synth, 1 hit
TIGRFAMsiTIGR02470 sucr_synth, 1 hit

Sequencei

Sequence statusi: Complete.

Q00917-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPTGRFETMR EWVYDAISAQ RNELLSLFSR YVAQGKGILQ SHQLIDEFLK
60 70 80 90 100
TVKVDGTLED LNKSPFMKVL QSAEEAIVLP PFVALAIRPR PGVREYVRVN
110 120 130 140 150
VYELSVDHLT VSEYLRFKEE LVNGHANGDY LLELDFEPFN ATLPRPTRSS
160 170 180 190 200
SIGNGVQFLN RHLSSIMFRN KESMEPLLEF LRTHKHDGRP MMLNDRIQNI
210 220 230 240 250
PILQGALARA EEFLSKLPLA TPYSEFEFEL QGMGFERGWG DTAQKVSEMV
260 270 280 290 300
HLLLDILQAP DPSVLETFLG RIPMVFNVVI LSPHGYFGQA NVLGLPDTGG
310 320 330 340 350
QVVYILDQVR ALENEMLLRI QKQGLEVIPK ILIVTRLLPE AKGTTCNQRL
360 370 380 390 400
ERVSGTEHAH ILRIPFRTEK GILRKWISRF DVWPYLETFA EDASNEISAE
410 420 430 440 450
LQGVPNLIIG NYSDGNLVAS LLASKLGVIQ CNIAHALEKT KYPESDIYWR
460 470 480 490 500
NHEDKYHFSS QFTADLIAMN NADFIITSTY QEIAGSKNNV GQYESHTAFT
510 520 530 540 550
MPGLYRVVHG IDVFDPKFNI VSPGADMTIY FPYSDKERRL TALHESIEEL
560 570 580 590 600
LFSAEQNDEH VGLLSDQSKP IIFSMARLDR VKNLTGLVEC YAKNSKLREL
610 620 630 640 650
ANLVIVGGYI DENQSRDREE MAEIQKMHSL IEQYDLHGEF RWIAAQMNRA
660 670 680 690 700
RNGELYRYIA DTKGVFVQPA FYEAFGLTVV ESMTCALPTF ATCHGGPAEI
710 720 730 740 750
IENGVSGFHI DPYHPDQVAA TLVSFFETCN TNPNHWVKIS EGGLKRIYER
760 770 780 790 800
YTWKKYSERL LTLAGVYAFW KHVSKLERRE TRRYLEMFYS LKFRDLANSI

PLATDEN
Length:807
Mass (Da):92,064
Last modified:January 25, 2012 - v3
Checksum:i48391FF65C4584DB
GO

Sequence cautioni

The sequence BAB10337 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence CAA43303 differs from that shown. Sequencing errors.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X60987 Genomic DNA Translation: CAA43303.1 Sequence problems.
AB016872 Genomic DNA Translation: BAB10337.1 Sequence problems.
CP002688 Genomic DNA Translation: AED95780.1
PIRiS19125 YUMU
RefSeqiNP_199730.1, NM_124296.3
UniGeneiAt.8597

Genome annotation databases

EnsemblPlantsiAT5G49190.1; AT5G49190.1; AT5G49190
GeneIDi834978
GrameneiAT5G49190.1; AT5G49190.1; AT5G49190
KEGGiath:AT5G49190

Similar proteinsi

Entry informationi

Entry nameiSUS2_ARATH
AccessioniPrimary (citable) accession number: Q00917
Secondary accession number(s): F4K4S0, Q9FJ20
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 1, 1993
Last sequence update: January 25, 2012
Last modified: April 25, 2018
This is version 121 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health