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Q00673

- NDUS3_CANMA

UniProt

Q00673 - NDUS3_CANMA

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Protein

Probable NADH-ubiquinone oxidoreductase 30.4 kDa subunit, mitochondrial

Gene

ALI1

Organism
Candida maltosa (Yeast)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). Essential for N-alkane assimilation.By similarity1 Publication

Catalytic activityi

NADH + ubiquinone + 5 H+(In) = NAD+ + ubiquinol + 4 H+(Out).
NADH + acceptor = NAD+ + reduced acceptor.

GO - Molecular functioni

  1. NADH dehydrogenase (ubiquinone) activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Biological processi

Electron transport, Respiratory chain, Transport

Keywords - Ligandi

NAD, Ubiquinone

Names & Taxonomyi

Protein namesi
Recommended name:
Probable NADH-ubiquinone oxidoreductase 30.4 kDa subunit, mitochondrial (EC:1.6.5.3, EC:1.6.99.3)
Alternative name(s):
Alkane-inducible protein 1
CI-31kD
Complex I-30kD
Gene namesi
Name:ALI1
OrganismiCandida maltosa (Yeast)
Taxonomic identifieri5479 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesDebaryomycetaceaeCandida/Lodderomyces cladeCandida

Subcellular locationi

GO - Cellular componenti

  1. mitochondrial inner membrane Source: UniProtKB-KW
  2. respiratory chain Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini? – 276Probable NADH-ubiquinone oxidoreductase 30.4 kDa subunit, mitochondrialPRO_0000020001
Transit peptidei1 – ?MitochondrionSequence Analysis

Interactioni

Subunit structurei

Complex I is composed of about 30 different subunits. This is a component of the iron-sulfur protein fraction.

Structurei

3D structure databases

ProteinModelPortaliQ00673.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the complex I 30 kDa subunit family.Curated

Keywords - Domaini

Transit peptide

Family and domain databases

HAMAPiMF_01357. NDH1_NuoC.
InterProiIPR010218. NADH_DH_suC.
IPR001268. NADH_UbQ_OxRdtase_30kDa_su.
IPR020396. NADH_UbQ_OxRdtase_CS.
[Graphical view]
PfamiPF00329. Complex1_30kDa. 1 hit.
[Graphical view]
ProDomiPD001581. NADH_UbQ_OxRdtase_30kDa_su. 1 hit.
[Graphical view] [Entries sharing at least one domain]
TIGRFAMsiTIGR01961. NuoC_fam. 1 hit.
PROSITEiPS00542. COMPLEX1_30K. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q00673-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MISRTLLKRT VPASRLLRSF TTSNVRLSAH EEDLVNVNNL PRPKPTENYV
60 70 80 90 100
PLINPTEKYK VQIEELHKFG TYIMSCLPKY IQQFSVWKDE LTIYVAPSAI
110 120 130 140 150
RPVMSYLKNH TSCQFKAVMD ITAADYPSRT NRFDVVYNLL SDRHNSRIRV
160 170 180 190 200
KTYANETSPV PSVTPLFNGA NWYERETYDL FGVFFVGHPD LRRIMTDYGF
210 220 230 240 250
EGHPLRKDFP TTGYTEVRYD EEKKRVIYEP LELTQAWRNF TVGSSVWEPV
260 270
GEGKDFTPES FKLPTPQPEP EQEEKK
Length:276
Mass (Da):32,158
Last modified:October 1, 1993 - v1
Checksum:i1CA55A6CF1459A72
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M61102 Genomic DNA. Translation: AAA34360.1.
PIRiJT0591.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M61102 Genomic DNA. Translation: AAA34360.1 .
PIRi JT0591.

3D structure databases

ProteinModelPortali Q00673.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Family and domain databases

HAMAPi MF_01357. NDH1_NuoC.
InterProi IPR010218. NADH_DH_suC.
IPR001268. NADH_UbQ_OxRdtase_30kDa_su.
IPR020396. NADH_UbQ_OxRdtase_CS.
[Graphical view ]
Pfami PF00329. Complex1_30kDa. 1 hit.
[Graphical view ]
ProDomi PD001581. NADH_UbQ_OxRdtase_30kDa_su. 1 hit.
[Graphical view ] [Entries sharing at least one domain ]
TIGRFAMsi TIGR01961. NuoC_fam. 1 hit.
PROSITEi PS00542. COMPLEX1_30K. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Sequences of two tandem genes regulated by carbon sources, one being essential for n-alkane assimilation in Candida maltosa."
    Hwang C.W., Yano K., Takagi M.
    Gene 106:61-69(1991) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], FUNCTION.
    Strain: ATCC 28140 / CBS 5611 / IAM 12247 / JCM 1504 / NBRC 1977.

Entry informationi

Entry nameiNDUS3_CANMA
AccessioniPrimary (citable) accession number: Q00673
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1993
Last sequence update: October 1, 1993
Last modified: October 29, 2014
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3