Q00673 (NDUS3_CANMA) Reviewed, UniProtKB/Swiss-Prot
Last modified
April 3, 2013.
Version 70.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: Probable NADH-ubiquinone oxidoreductase 30.4 kDa subunit, mitochondrial EC=1.6.5.3 EC=1.6.99.3 Alternative name(s): Alkane-inducible protein 1 CI-31kD Complex I-30kD | ||
| Gene names |
| ||
| Organism | Candida maltosa (Yeast) | ||
| Taxonomic identifier | 5479 [NCBI] | ||
| Taxonomic lineage | Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › mitosporic Saccharomycetales › Candida![]() |
Protein attributes
| Sequence length | 276 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is further processed into a mature form. |
| Protein existence | Inferred from homology |
General annotation (Comments)
| Function | Essential for N-alkane assimilation. Ref.2 Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone By similarity. Ref.2 |
| Catalytic activity | NADH + ubiquinone = NAD+ + ubiquinol. NADH + acceptor = NAD+ + reduced acceptor. |
| Subunit structure | Complex I is composed of about 30 different subunits. This is a component of the iron-sulfur protein fraction. |
| Subcellular location | |
| Sequence similarities | Belongs to the complex I 30 kDa subunit family. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Electron transport Respiratory chain Transport |
| Cellular component | Membrane Mitochondrion Mitochondrion inner membrane |
| Domain | Transit peptide |
| Ligand | NAD Ubiquinone |
| Molecular function | Oxidoreductase |
| Gene Ontology (GO) | |
| Biological_process | electron transport chain Inferred from electronic annotation. Source: UniProtKB-KW |
| Cellular_component | mitochondrial inner membrane Inferred from electronic annotation. Source: UniProtKB-SubCell respiratory chainInferred from electronic annotation. Source: UniProtKB-KW |
| Molecular_function | NADH dehydrogenase (ubiquinone) activity Inferred from electronic annotation. Source: EC |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | |
Molecule processing | ||||||
|---|---|---|---|---|---|---|
| Transit peptide | 1 – ? | Mitochondrion Potential | ||||
| Chain | ? – 276 | Probable NADH-ubiquinone oxidoreductase 30.4 kDa subunit, mitochondrial | PRO_0000020001 | |||
Sequences
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References
| [1] | "Sequences of two tandem genes regulated by carbon sources, one being essential for n-alkane assimilation in Candida maltosa." Hwang C.W., Yano K., Takagi M. Gene 106:61-69(1991) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. |
| [2] | Bairoch A. Unpublished observations (OCT-1993) Cited for: POSSIBLE FUNCTION. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | M61102 Genomic DNA. Translation: AAA34360.1. |
| PIR | JT0591. |
3D structure databases | |
| ProteinModelPortal | Q00673. |
| ModBase | Search... |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Family and domain databases | |
| InterPro | IPR010218. NADH_DH_suC. IPR001268. NADH_UbQ_OxRdtase_30kDa_su. IPR020396. NADH_UbQ_OxRdtase_CS. [Graphical view] |
| Pfam | PF00329. Complex1_30kDa. 1 hit. [Graphical view] |
| ProDom | PD001581. NADH_UbQ_OxRdtase_30kDa_su. 1 hit. [Graphical view] [Entries sharing at least one domain] |
| TIGRFAMs | TIGR01961. NuoC_fam. 1 hit. |
| PROSITE | PS00542. COMPLEX1_30K. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | NDUS3_CANMA | ||||||||
| Accession | Primary (citable) accession number: Q00673 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Fungal Protein Annotation Program | ||||||||
Relevant documents
| SIMILARITY comments Index of protein domains and families |

Clusters with
