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Q00587

- BORG5_HUMAN

UniProt

Q00587 - BORG5_HUMAN

Protein

Cdc42 effector protein 1

Gene

CDC42EP1

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli
    • BLAST
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    • History
      Entry version 131 (01 Oct 2014)
      Sequence version 1 (01 Feb 1994)
      Previous versions | rss
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    Functioni

    Probably involved in the organization of the actin cytoskeleton. Induced membrane extensions in fibroblasts.1 Publication

    GO - Molecular functioni

    1. protein binding Source: IntAct

    GO - Biological processi

    1. positive regulation of pseudopodium assembly Source: UniProtKB
    2. regulation of cell shape Source: UniProtKB
    3. Rho protein signal transduction Source: Ensembl

    Enzyme and pathway databases

    SignaLinkiQ00587.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Cdc42 effector protein 1
    Alternative name(s):
    Binder of Rho GTPases 5
    Serum protein MSE55
    Gene namesi
    Name:CDC42EP1
    Synonyms:BORG5, CEP1, MSE55
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 22

    Organism-specific databases

    HGNCiHGNC:17014. CDC42EP1.

    Subcellular locationi

    Endomembrane system 1 Publication; Peripheral membrane protein 1 Publication. Cytoplasmcytoskeleton 1 Publication

    GO - Cellular componenti

    1. actin cytoskeleton Source: HPA
    2. cytoplasm Source: HPA
    3. Golgi apparatus Source: HPA
    4. plasma membrane Source: HPA

    Keywords - Cellular componenti

    Cytoplasm, Cytoskeleton, Membrane

    Pathology & Biotechi

    Mutagenesis

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Mutagenesisi36 – 4712DMISH…GDFRH → AMISHALGDFRA: No binding with CDC42. 1 PublicationAdd
    BLAST

    Organism-specific databases

    PharmGKBiPA38430.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 391391Cdc42 effector protein 1PRO_0000212657Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei19 – 191Phosphoserine1 Publication
    Modified residuei101 – 1011Phosphoserine2 Publications
    Modified residuei113 – 1131Phosphoserine2 Publications
    Modified residuei121 – 1211Phosphoserine3 Publications
    Modified residuei190 – 1901Phosphoserine1 Publication
    Modified residuei192 – 1921Phosphoserine3 Publications
    Modified residuei195 – 1951Phosphoserine1 Publication
    Modified residuei350 – 3501Phosphoserine3 Publications
    Modified residuei353 – 3531Phosphoserine2 Publications

    Keywords - PTMi

    Phosphoprotein

    Proteomic databases

    MaxQBiQ00587.
    PaxDbiQ00587.
    PRIDEiQ00587.

    PTM databases

    PhosphoSiteiQ00587.

    Expressioni

    Tissue specificityi

    Endothelial and bone marrow stromal cells.

    Gene expression databases

    ArrayExpressiQ00587.
    BgeeiQ00587.
    CleanExiHS_CDC42EP1.
    GenevestigatoriQ00587.

    Organism-specific databases

    HPAiHPA006379.

    Interactioni

    Subunit structurei

    Interacts with RHOQ and CDC42, in a GTP-dependent manner.2 Publications

    Binary interactionsi

    WithEntry#Exp.IntActNotes
    CDC42P609533EBI-744130,EBI-81752

    Protein-protein interaction databases

    BioGridi116308. 10 interactions.
    IntActiQ00587. 12 interactions.
    MINTiMINT-1454089.
    STRINGi9606.ENSP00000249014.

    Structurei

    3D structure databases

    ProteinModelPortaliQ00587.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini38 – 5215CRIBPROSITE-ProRule annotationAdd
    BLAST
    Repeati220 – 22671
    Repeati227 – 23372
    Repeati234 – 24073
    Repeati241 – 24774
    Repeati248 – 25475
    Repeati255 – 26176
    Repeati262 – 26877
    Repeati269 – 27578

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni220 – 275568 X 7 AA tandem repeats of [PT]-[AT]-A-[ENT]-[PT]-[PTS]-[AG]Add
    BLAST

    Domaini

    The CRIB domain mediates interaction with CDC42.

    Sequence similaritiesi

    Belongs to the BORG/CEP family.Curated
    Contains 1 CRIB domain.PROSITE-ProRule annotation

    Keywords - Domaini

    Repeat

    Phylogenomic databases

    eggNOGiNOG45247.
    HOGENOMiHOG000095252.
    HOVERGENiHBG080906.
    InParanoidiQ00587.
    OMAiTVQANTF.
    OrthoDBiEOG7V1FSH.
    PhylomeDBiQ00587.
    TreeFamiTF331725.

    Family and domain databases

    InterProiIPR029273. Cdc42_effect.
    IPR000095. CRIB_dom.
    [Graphical view]
    PfamiPF14957. BORG_CEP. 1 hit.
    PF00786. PBD. 1 hit.
    [Graphical view]
    SMARTiSM00285. PBD. 1 hit.
    [Graphical view]
    PROSITEiPS50108. CRIB. 1 hit.
    [Graphical view]

    Sequences (2)i

    Sequence statusi: Complete.

    This entry describes 2 isoformsi produced by alternative splicing. Align

    Isoform 1 (identifier: Q00587-1) [UniParc]FASTAAdd to Basket

    This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

    « Hide

    MPGPQGGRGA ATMSLGKLSP VGWVSSSQGK RRLTADMISH PLGDFRHTMH    50
    VGRGGDVFGD TSFLSNHGGS SGSTHRSPRS FLAKKLQLVR RVGAPPRRMA 100
    SPPAPSPAPP AISPIIKNAI SLPQLNQAAY DSLVVGKLSF DSSPTSSTDG 150
    HSSYGLDSGF CTISRLPRSE KPHDRDRDGS FPSEPGLRRS DSLLSFRLDL 200
    DLGPSLLSEL LGVMSLPEAP AAETPAPAAN PPAPTANPTG PAANPPATTA 250
    NPPAPAANPS APAATPTGPA ANPPAPAASS TPHGHCPNGV TAGLGPVAEV 300
    KSSPVGGGPR GPAGPALGRH WGAGWDGGHH YPEMDARQER VEVLPQARAS 350
    WESLDEEWRA PQAGSRTPVP STVQANTFEF ADAEEDDEVK V 391
    Length:391
    Mass (Da):40,295
    Last modified:February 1, 1994 - v1
    Checksum:i625EA3C71F20CF2B
    GO
    Isoform 2 (identifier: Q00587-2) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         258-264: Missing.

    Show »
    Length:384
    Mass (Da):39,686
    Checksum:i3D056D62399AE422
    GO

    Alternative sequence

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Alternative sequencei258 – 2647Missing in isoform 2. 2 PublicationsVSP_004325

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    M88338 mRNA. Translation: AAA36606.1.
    CR456524 mRNA. Translation: CAG30410.1.
    AK292190 mRNA. Translation: BAF84879.1.
    AL022315 Genomic DNA. Translation: CAB42833.1.
    CH471095 Genomic DNA. Translation: EAW60164.1.
    BC009356 mRNA. Translation: AAH09356.1.
    CCDSiCCDS13949.1. [Q00587-1]
    PIRiA42973.
    RefSeqiNP_689449.1. NM_152243.2. [Q00587-1]
    XP_006724170.1. XM_006724107.1. [Q00587-1]
    XP_006724171.1. XM_006724108.1. [Q00587-1]
    XP_006724172.1. XM_006724109.1. [Q00587-1]
    UniGeneiHs.225356.

    Genome annotation databases

    EnsembliENST00000249014; ENSP00000249014; ENSG00000128283. [Q00587-1]
    GeneIDi11135.
    KEGGihsa:11135.
    UCSCiuc003asz.4. human. [Q00587-1]

    Polymorphism databases

    DMDMi462623.

    Keywords - Coding sequence diversityi

    Alternative splicing

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    M88338 mRNA. Translation: AAA36606.1 .
    CR456524 mRNA. Translation: CAG30410.1 .
    AK292190 mRNA. Translation: BAF84879.1 .
    AL022315 Genomic DNA. Translation: CAB42833.1 .
    CH471095 Genomic DNA. Translation: EAW60164.1 .
    BC009356 mRNA. Translation: AAH09356.1 .
    CCDSi CCDS13949.1. [Q00587-1 ]
    PIRi A42973.
    RefSeqi NP_689449.1. NM_152243.2. [Q00587-1 ]
    XP_006724170.1. XM_006724107.1. [Q00587-1 ]
    XP_006724171.1. XM_006724108.1. [Q00587-1 ]
    XP_006724172.1. XM_006724109.1. [Q00587-1 ]
    UniGenei Hs.225356.

    3D structure databases

    ProteinModelPortali Q00587.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 116308. 10 interactions.
    IntActi Q00587. 12 interactions.
    MINTi MINT-1454089.
    STRINGi 9606.ENSP00000249014.

    PTM databases

    PhosphoSitei Q00587.

    Polymorphism databases

    DMDMi 462623.

    Proteomic databases

    MaxQBi Q00587.
    PaxDbi Q00587.
    PRIDEi Q00587.

    Protocols and materials databases

    DNASUi 11135.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000249014 ; ENSP00000249014 ; ENSG00000128283 . [Q00587-1 ]
    GeneIDi 11135.
    KEGGi hsa:11135.
    UCSCi uc003asz.4. human. [Q00587-1 ]

    Organism-specific databases

    CTDi 11135.
    GeneCardsi GC22P037956.
    H-InvDB HIX0016445.
    HGNCi HGNC:17014. CDC42EP1.
    HPAi HPA006379.
    MIMi 606084. gene.
    neXtProti NX_Q00587.
    PharmGKBi PA38430.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi NOG45247.
    HOGENOMi HOG000095252.
    HOVERGENi HBG080906.
    InParanoidi Q00587.
    OMAi TVQANTF.
    OrthoDBi EOG7V1FSH.
    PhylomeDBi Q00587.
    TreeFami TF331725.

    Enzyme and pathway databases

    SignaLinki Q00587.

    Miscellaneous databases

    GeneWikii CDC42EP1.
    GenomeRNAii 11135.
    NextBioi 42326.
    PROi Q00587.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi Q00587.
    Bgeei Q00587.
    CleanExi HS_CDC42EP1.
    Genevestigatori Q00587.

    Family and domain databases

    InterProi IPR029273. Cdc42_effect.
    IPR000095. CRIB_dom.
    [Graphical view ]
    Pfami PF14957. BORG_CEP. 1 hit.
    PF00786. PBD. 1 hit.
    [Graphical view ]
    SMARTi SM00285. PBD. 1 hit.
    [Graphical view ]
    PROSITEi PS50108. CRIB. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "cDNA cloning and molecular characterization of MSE55, a novel human serum constituent protein that displays bone marrow stromal/endothelial cell-specific expression."
      Bahou W.F., Campbell A.D., Wicha M.S.
      J. Biol. Chem. 267:13986-13992(1992) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
    3. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
      , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
      Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
      Tissue: Mammary gland.
    4. "The DNA sequence of human chromosome 22."
      Dunham I., Hunt A.R., Collins J.E., Bruskiewich R., Beare D.M., Clamp M., Smink L.J., Ainscough R., Almeida J.P., Babbage A.K., Bagguley C., Bailey J., Barlow K.F., Bates K.N., Beasley O.P., Bird C.P., Blakey S.E., Bridgeman A.M.
      , Buck D., Burgess J., Burrill W.D., Burton J., Carder C., Carter N.P., Chen Y., Clark G., Clegg S.M., Cobley V.E., Cole C.G., Collier R.E., Connor R., Conroy D., Corby N.R., Coville G.J., Cox A.V., Davis J., Dawson E., Dhami P.D., Dockree C., Dodsworth S.J., Durbin R.M., Ellington A.G., Evans K.L., Fey J.M., Fleming K., French L., Garner A.A., Gilbert J.G.R., Goward M.E., Grafham D.V., Griffiths M.N.D., Hall C., Hall R.E., Hall-Tamlyn G., Heathcott R.W., Ho S., Holmes S., Hunt S.E., Jones M.C., Kershaw J., Kimberley A.M., King A., Laird G.K., Langford C.F., Leversha M.A., Lloyd C., Lloyd D.M., Martyn I.D., Mashreghi-Mohammadi M., Matthews L.H., Mccann O.T., Mcclay J., Mclaren S., McMurray A.A., Milne S.A., Mortimore B.J., Odell C.N., Pavitt R., Pearce A.V., Pearson D., Phillimore B.J.C.T., Phillips S.H., Plumb R.W., Ramsay H., Ramsey Y., Rogers L., Ross M.T., Scott C.E., Sehra H.K., Skuce C.D., Smalley S., Smith M.L., Soderlund C., Spragon L., Steward C.A., Sulston J.E., Swann R.M., Vaudin M., Wall M., Wallis J.M., Whiteley M.N., Willey D.L., Williams L., Williams S.A., Williamson H., Wilmer T.E., Wilming L., Wright C.L., Hubbard T., Bentley D.R., Beck S., Rogers J., Shimizu N., Minoshima S., Kawasaki K., Sasaki T., Asakawa S., Kudoh J., Shintani A., Shibuya K., Yoshizaki Y., Aoki N., Mitsuyama S., Roe B.A., Chen F., Chu L., Crabtree J., Deschamps S., Do A., Do T., Dorman A., Fang F., Fu Y., Hu P., Hua A., Kenton S., Lai H., Lao H.I., Lewis J., Lewis S., Lin S.-P., Loh P., Malaj E., Nguyen T., Pan H., Phan S., Qi S., Qian Y., Ray L., Ren Q., Shaull S., Sloan D., Song L., Wang Q., Wang Y., Wang Z., White J., Willingham D., Wu H., Yao Z., Zhan M., Zhang G., Chissoe S., Murray J., Miller N., Minx P., Fulton R., Johnson D., Bemis G., Bentley D., Bradshaw H., Bourne S., Cordes M., Du Z., Fulton L., Goela D., Graves T., Hawkins J., Hinds K., Kemp K., Latreille P., Layman D., Ozersky P., Rohlfing T., Scheet P., Walker C., Wamsley A., Wohldmann P., Pepin K., Nelson J., Korf I., Bedell J.A., Hillier L.W., Mardis E., Waterston R., Wilson R., Emanuel B.S., Shaikh T., Kurahashi H., Saitta S., Budarf M.L., McDermid H.E., Johnson A., Wong A.C.C., Morrow B.E., Edelmann L., Kim U.J., Shizuya H., Simon M.I., Dumanski J.P., Peyrard M., Kedra D., Seroussi E., Fransson I., Tapia I., Bruder C.E., O'Brien K.P., Wilkinson P., Bodenteich A., Hartman K., Hu X., Khan A.S., Lane L., Tilahun Y., Wright H.
      Nature 402:489-495(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    5. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    6. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
      Tissue: Pancreas.
    7. "Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides."
      Gevaert K., Goethals M., Martens L., Van Damme J., Staes A., Thomas G.R., Vandekerckhove J.
      Nat. Biotechnol. 21:566-569(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: PROTEIN SEQUENCE OF 166-175.
      Tissue: Platelet.
    8. "The Borgs, a new family of Cdc42 and TC10 GTPase-interacting proteins."
      Joberty G., Perlungher R.R., Macara I.G.
      Mol. Cell. Biol. 19:6585-6597(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: INTERACTION WITH RHOQ AND CDC42.
      Tissue: Embryo.
    9. "MSE55, a Cdc42 effector protein, induces long cellular extensions in fibroblasts."
      Burbelo P.D., Snow D.M., Bahou W., Spiegel S.
      Proc. Natl. Acad. Sci. U.S.A. 96:9083-9088(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION, INTERACTION WITH CDC42, SUBCELLULAR LOCATION, MUTAGENESIS OF 36-ASP--HIS-47.
    10. "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."
      Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P., Mann M.
      Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Tissue: Cervix carcinoma.
    11. "Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis."
      Cantin G.T., Yi W., Lu B., Park S.K., Xu T., Lee J.-D., Yates J.R. III
      J. Proteome Res. 7:1346-1351(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Tissue: Cervix carcinoma.
    12. "Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle."
      Daub H., Olsen J.V., Bairlein M., Gnad F., Oppermann F.S., Korner R., Greff Z., Keri G., Stemmann O., Mann M.
      Mol. Cell 31:438-448(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-19; SER-101; SER-113; SER-121 AND SER-350, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Tissue: Cervix carcinoma.
    13. Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-121; SER-190; SER-192; SER-195; SER-350 AND SER-353, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Tissue: Cervix carcinoma.
    14. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
      Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J., Mohammed S.
      Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    15. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
      Olsen J.V., Vermeulen M., Santamaria A., Kumar C., Miller M.L., Jensen L.J., Gnad F., Cox J., Jensen T.S., Nigg E.A., Brunak S., Mann M.
      Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
      Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-101; SER-113; SER-121; SER-192; SER-350 AND SER-353, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Tissue: Cervix carcinoma.
    16. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
      Rigbolt K.T., Prokhorova T.A., Akimov V., Henningsen J., Johansen P.T., Kratchmarova I., Kassem M., Mann M., Olsen J.V., Blagoev B.
      Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
      Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-192, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

    Entry informationi

    Entry nameiBORG5_HUMAN
    AccessioniPrimary (citable) accession number: Q00587
    Secondary accession number(s): A8K825, Q96GN1
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 1, 1994
    Last sequence update: February 1, 1994
    Last modified: October 1, 2014
    This is version 131 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Direct protein sequencing, Reference proteome

    Documents

    1. Human chromosome 22
      Human chromosome 22: entries, gene names and cross-references to MIM
    2. MIM cross-references
      Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3