Q00500 (CCMF_RHOCB) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Cytochrome c-type biogenesis protein ccl1

Gene names

Name:	ccl1
Synonyms:	ccmF
Ordered Locus Names:	RCAP_rcc03136

Organism

Rhodobacter capsulatus (strain ATCC BAA-309 / NBRC 16581 / SB1003) [Complete proteome] [HAMAP]

Taxonomic identifier

272942 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rhodobacterales › Rhodobacteraceae › Rhodobacter › Rhodobacter capsulatus

Protein attributes

Sequence length	653 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Required for the biogenesis of c-type cytochromes. Possible subunit of a heme lyase.
Subcellular location	Cell inner membrane; Multi-pass membrane protein Potential.
Sequence similarities	Belongs to the ccmF/cycK/ccl1/nrfE/ccsA family.

Ontologies

Keywords
Biological process	Cytochrome c-type biogenesis
Cellular component	Cell inner membrane Cell membrane Membrane
Domain	Transmembrane Transmembrane helix
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	cytochrome complex assembly Inferred from electronic annotation. Source: UniProtKB-KW respiratory chain complex IV assembly Inferred from electronic annotation. Source: InterPro
Cellular_component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	heme transporter activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 653	653	Cytochrome c-type biogenesis protein ccl1		PRO_0000201588
Regions
	Transmembrane	8 – 28	21	Helical; Potential
	Transmembrane	42 – 62	21	Helical; Potential
	Transmembrane	97 – 117	21	Helical; Potential
	Transmembrane	125 – 145	21	Helical; Potential
	Transmembrane	175 – 195	21	Helical; Potential
	Transmembrane	210 – 230	21	Helical; Potential
	Transmembrane	245 – 265	21	Helical; Potential
	Transmembrane	273 – 293	21	Helical; Potential
	Transmembrane	311 – 331	21	Helical; Potential
	Transmembrane	358 – 378	21	Helical; Potential
	Transmembrane	393 – 413	21	Helical; Potential
	Transmembrane	425 – 445	21	Helical; Potential
	Transmembrane	449 – 469	21	Helical; Potential
	Transmembrane	491 – 511	21	Helical; Potential
	Transmembrane	610 – 630	21	Helical; Potential

Sequences

	Sequence		Length	Mass (Da)
	Q00500 [UniParc]. Last modified July 1, 1993. Version 1. Checksum: D0FB1A80FDCCE857	FASTA	653	70,552
	10 20 30 40 50 60 MIVETGHFAL ILALCVALVQ AVIPLVGAQK GWSGWMAVAT PAALAQFGLI AIAFAALTYA 70 80 90 100 110 120 FVTSDFSLKL VYENSHTDKP MLYKVTGVWG NHEGSMLLWV LILAMFGAAA AAFGGALPER 130 140 150 160 170 180 LRARVLAVQG TIGVAFLVFV LFTSNPFLRL EEAPFNGRDM NPLLQDPGLA FHPPFLYLGY 190 200 210 220 230 240 VGLSMAFSFA VAALIEGRVD AAWARWVRPW TLAAWIFLTI GIALGSWWAY YELGWGGFWF 250 260 270 280 290 300 WDPVENASLM PWLLAAALLH SAIVVEKREA LKSWTILLAI MAFGFSLIGT FLVRSGVISS 310 320 330 340 350 360 VHSFANDPER GVFILFILAF FTGGALTLYA ARASEMQAKG LFSMVSRESA LVMNNVLLAV 370 380 390 400 410 420 AALVVFTGTV WPLIAELFWD RKLSVGAPFF EKAFTPFMVG LALLLPLGSM MPWKRASLGK 430 440 450 460 470 480 LVRPLLPALV LTLAVLALVW VMATGRPMLA LGAAGLGAWI LFGALAEIWQ RAGRTPGRIL 490 500 510 520 530 540 RLPRADWGKA FAHGGLGIVF AGVGLLMAGQ VEDIRVAKAG DSFEVAGYTI TLVSVEDVPG 550 560 570 580 590 600 PNFTAKTATM EVRQGGKLVA TLHPEKRIYP VQAMPTTEAD IDNGFWRDVY LVIGDPQEGG 610 620 630 640 650 GWAVRTYVKP FANWIWAGCL LMAFGGGLSL TDRRYRSAAG ARRATVADAV AAE

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Bacterial cytochromes c biogenesis." Beckman D.L., Trawick D.R., Kranz R.G. Genes Dev. 6:268-283(1992) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC BAA-309 / NBRC 16581 / SB1003.
[2]	"Complete genome sequence of the photosynthetic purple nonsulfur bacterium Rhodobacter capsulatus SB 1003." Strnad H., Lapidus A., Paces J., Ulbrich P., Vlcek C., Paces V., Haselkorn R. J. Bacteriol. 192:3545-3546(2010) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-309 / NBRC 16581 / SB1003.

Cross-references

Sequence databases
EMBL GenBank DDBJ	X63461 Genomic DNA. Translation: CAA45058.1. CP001312 Genomic DNA. Translation: ADE86860.1.
PIR	S23667.
RefSeq	YP_003579267.1. NC_014034.1.
3D structure databases
ModBase	Search...
Protein family/group databases
TCDB	9.B.14.1.1. putative heme handling protein (HHP) family.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ADE86860; ADE86860; RCAP_rcc03136.
GeneID	9005952.
KEGG	rcp:RCAP_rcc03136.
PATRIC	35506478. VBIRhoCap134200_3174.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HOG000274659.
KO	K02198.
OMA	CLTYAFM.
ProtClustDB	CLSK835968.
Enzyme and pathway databases
BioCyc	RCAP272942:GJIY-3179-MONOMER.
Family and domain databases
InterPro	IPR002541. Cyt_c_assembly. IPR003567. Cyt_c_biogenesis. IPR003568. Cyt_c_biogenesis_CcmF. [Graphical view]
Pfam	PF01578. Cytochrom_C_asm. 1 hit. [Graphical view]
PRINTS	PR01410. CCBIOGENESIS. PR01411. CCMFBIOGNSIS.
TIGRFAMs	TIGR00353. nrfE. 1 hit.
ProtoNet	Search...

Entry information

Entry name

CCMF_RHOCB

Accession

Primary (citable) accession number: Q00500
Secondary accession number(s): D5AR55

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 1, 1993
Last sequence update:	July 1, 1993
Last modified:	May 1, 2013
This is version 73 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program