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Protein
Submitted name:

Arginine kinase

Gene
N/A
Organism
Litopenaeus vannamei (Whiteleg shrimp) (Penaeus vannamei)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei185 – 1851ADPCombined sources
Binding sitei229 – 2291ADPCombined sources

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi122 – 1265ADPCombined sources
Nucleotide bindingi280 – 2845ADPCombined sources
Nucleotide bindingi309 – 3146ADPCombined sources

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotationSAAS annotationImported, Transferase

Keywords - Ligandi

ATP-bindingSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

BRENDAi2.7.3.3. 4594.

Names & Taxonomyi

Protein namesi
Submitted name:
Arginine kinaseImported (EC:2.7.3.3Imported)
OrganismiLitopenaeus vannamei (Whiteleg shrimp) (Penaeus vannamei)Imported
Taxonomic identifieri6689 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaCrustaceaMalacostracaEumalacostracaEucaridaDecapodaDendrobranchiataPenaeoideaPenaeidaeLitopenaeus

Pathology & Biotechi

Protein family/group databases

Allergomei3544. Lit v 2.
3616. Lit v 2.0101.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4AM1X-ray1.25A2-356[»]
4BG4X-ray1.60A/B1-356[»]
4BHLX-ray1.90A1-356[»]
ProteinModelPortaliQ004B5.
SMRiQ004B5. Positions 3-354.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini9 – 9183Phosphagen kinase N-terminalInterPro annotationAdd
BLAST
Domaini119 – 356238Phosphagen kinase C-terminalInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the ATP:guanido phosphotransferase family.UniRule annotationSAAS annotation

Family and domain databases

Gene3Di1.10.135.10. 1 hit.
3.30.590.10. 1 hit.
InterProiIPR000749. ATP-guanido_PTrfase.
IPR022415. ATP-guanido_PTrfase_AS.
IPR022414. ATP-guanido_PTrfase_cat.
IPR022413. ATP-guanido_PTrfase_N.
IPR014746. Gln_synth/guanido_kin_cat_dom.
[Graphical view]
PANTHERiPTHR11547. PTHR11547. 1 hit.
PfamiPF00217. ATP-gua_Ptrans. 1 hit.
PF02807. ATP-gua_PtransN. 1 hit.
[Graphical view]
SUPFAMiSSF48034. SSF48034. 1 hit.
PROSITEiPS00112. PHOSPHAGEN_KINASE. 1 hit.
PS51510. PHOSPHAGEN_KINASE_C. 1 hit.
PS51509. PHOSPHAGEN_KINASE_N. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q004B5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MADAAVIEKL EAGFKKLEAA TDCKSLLKKY LTKEVFDKLK DKRTSLGATL
60 70 80 90 100
LDVIQSGVEN LDSGVGIYAP DAEAYTLFAP LFDPIIEDYH VGFKQTDKHP
110 120 130 140 150
NKDFGDVNSF VNVDPEGKFV ISTRVRCGRS LQGYPFNPCL TESQYKEMEA
160 170 180 190 200
KVSSTLSSLE GELKGTYYPL TGMSKEVQQK LIDDHFLFKE GDRFLQAANA
210 220 230 240 250
CRYWPAGRGI YHNDNKTFLV WVNEEDHLRI ISMQMGGDLG QVFRRLTSAV
260 270 280 290 300
NEIEKRIPFS HHDRLGFLTF CPTNLGTTVR ASVHIKLPKL AANREKLEEV
310 320 330 340 350
AGKYNLQVRG TRGEHTEAEG GIYDISNKRR MGLTEFQAVK EMQDGILELI

KIEKEM
Length:356
Mass (Da):40,160
Last modified:November 14, 2006 - v1
Checksum:i1CFF023A35E0036A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ975203 mRNA. Translation: ABI98020.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ975203 mRNA. Translation: ABI98020.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4AM1X-ray1.25A2-356[»]
4BG4X-ray1.60A/B1-356[»]
4BHLX-ray1.90A1-356[»]
ProteinModelPortaliQ004B5.
SMRiQ004B5. Positions 3-354.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

Allergomei3544. Lit v 2.
3616. Lit v 2.0101.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Enzyme and pathway databases

BRENDAi2.7.3.3. 4594.

Family and domain databases

Gene3Di1.10.135.10. 1 hit.
3.30.590.10. 1 hit.
InterProiIPR000749. ATP-guanido_PTrfase.
IPR022415. ATP-guanido_PTrfase_AS.
IPR022414. ATP-guanido_PTrfase_cat.
IPR022413. ATP-guanido_PTrfase_N.
IPR014746. Gln_synth/guanido_kin_cat_dom.
[Graphical view]
PANTHERiPTHR11547. PTHR11547. 1 hit.
PfamiPF00217. ATP-gua_Ptrans. 1 hit.
PF02807. ATP-gua_PtransN. 1 hit.
[Graphical view]
SUPFAMiSSF48034. SSF48034. 1 hit.
PROSITEiPS00112. PHOSPHAGEN_KINASE. 1 hit.
PS51510. PHOSPHAGEN_KINASE_C. 1 hit.
PS51509. PHOSPHAGEN_KINASE_N. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Molecular characterization of arginine kinase, an allergen from the shrimp Litopenaeus vannamei."
    Garcia-Orozco K.D., Aispuro-Hernandez E., Yepiz-Plascencia G., Calderon-de-la-Barca A.M., Sotelo-Mundo R.R.
    Int. Arch. Allergy Immunol. 144:23-28(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: MuscleImported.
  2. "Crystallization and X-ray diffraction studies of arginine kinase from the white Pacific shrimp Litopenaeus vannamei."
    Lopez-Zavala A.A., Sotelo-Mundo R.R., Garcia-Orozco K.D., Isac-Martinez F., Brieba L.G., Rudino-Pinera E.
    Acta Crystallogr. F 68:783-785(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (1.25 ANGSTROMS) OF 2-356.
  3. "Crystal structure of shrimp arginine kinase in binary complex with arginine-a molecular view of the phosphagen precursor binding to the enzyme."
    Lopez-Zavala A.A., Garcia-Orozco K.D., Carrasco-Miranda J.S., Sugich-Miranda R., Velazquez-Contreras E.F., Criscitiello M.F., Brieba L.G., Rudino-Pinera E., Sotelo-Mundo R.R.
    J. Bioenerg. Biomembr. 45:511-518(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (1.60 ANGSTROMS) IN COMPLEX WITH ADP.

Entry informationi

Entry nameiQ004B5_LITVA
AccessioniPrimary (citable) accession number: Q004B5
Entry historyi
Integrated into UniProtKB/TrEMBL: November 14, 2006
Last sequence update: November 14, 2006
Last modified: May 11, 2016
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.