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Q00468

- ACOX2_CANMA

UniProt

Q00468 - ACOX2_CANMA

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Protein

Acyl-coenzyme A oxidase 2

Gene

POX2

Organism
Candida maltosa (Yeast)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

Acyl-CoA + O2 = trans-2,3-dehydroacyl-CoA + H2O2.

Cofactori

Pathwayi

GO - Molecular functioni

  1. acyl-CoA dehydrogenase activity Source: InterPro
  2. acyl-CoA oxidase activity Source: UniProtKB-EC
  3. flavin adenine dinucleotide binding Source: InterPro

GO - Biological processi

  1. fatty acid beta-oxidation using acyl-CoA oxidase Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Biological processi

Fatty acid metabolism, Lipid metabolism

Keywords - Ligandi

FAD, Flavoprotein

Enzyme and pathway databases

UniPathwayiUPA00661.

Names & Taxonomyi

Protein namesi
Recommended name:
Acyl-coenzyme A oxidase 2 (EC:1.3.3.6)
Short name:
AOX 2
Short name:
Acyl-CoA oxidase 2
Gene namesi
Name:POX2
OrganismiCandida maltosa (Yeast)
Taxonomic identifieri5479 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesDebaryomycetaceaeCandida/Lodderomyces cladeCandida

Subcellular locationi

GO - Cellular componenti

  1. peroxisome Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Peroxisome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 724724Acyl-coenzyme A oxidase 2PRO_0000204693Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliQ00468.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the acyl-CoA oxidase family.Curated

Family and domain databases

Gene3Di1.10.540.10. 1 hit.
2.40.110.10. 1 hit.
InterProiIPR029320. Acyl-CoA_ox_N.
IPR006091. Acyl-CoA_Oxase/DH_cen-dom.
IPR012258. Acyl-CoA_oxidase.
IPR002655. Acyl-CoA_oxidase_C.
IPR009075. AcylCo_DH/oxidase_C.
IPR013786. AcylCoA_DH/ox_N.
IPR009100. AcylCoA_DH/oxidase_NM_dom.
[Graphical view]
PfamiPF01756. ACOX. 1 hit.
PF02770. Acyl-CoA_dh_M. 1 hit.
PF14749. Acyl-CoA_ox_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000168. Acyl-CoA_oxidase. 1 hit.
SUPFAMiSSF47203. SSF47203. 2 hits.
SSF56645. SSF56645. 1 hit.

Sequencei

Sequence statusi: Complete.

Q00468-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MALISNLKDE YDHPTKTDPD TNPKIVADII SSKEPPQPSQ DVAEERSRTD
60 70 80 90 100
WDLKEMHEFL EGDEAKSEEI LRLYQSIERD PILQTRPEQF DYTKNEERES
110 120 130 140 150
VALRINQMSK YLETEPYEKF RRRLQLMTVN DPSLGIRMLV NIGLFLNCIR
160 170 180 190 200
GNGTQKQYDF WAKTKEAGKV KQLLRLFRYD ELGHGFNVAG CEIFATFDEK
210 220 230 240 250
TDQFIIDTPH IGATKWWIGG AAHSATHTVC YARLIVKDID YGVKTFVVPL
260 270 280 290 300
RDSTHNLLPG VAIGDIGPKL GRQGVDNGWI QFTEVRIPRF FMLQRWCKVD
310 320 330 340 350
RQGNVTLPPL EQLSYISLLE GRVGMATDSY RIGARYTTIA LRYAVARRQF
360 370 380 390 400
SKGDGQPETK LIDYTLHQRR LLPYLALTYL AALGTDKLER QHDQLLKNLD
410 420 430 440 450
KALATNNKLL LKNTIQSTKS MFVDSGSLKS TLTWLASDLI NEARQSCGGH
460 470 480 490 500
GYSAYNGFGK TYGDWAVQCT WEGDNNVLGM SAGKTIIKTV QQVLNGKQLK
510 520 530 540 550
DSTLEFLNDA PALSSAKKAV IRIKSHVDDT DRVLKAIAGL ISKYAKDLIP
560 570 580 590 600
VSYQSWDSIG PQRVVLSKFR CHYYLLETFN ERLNDRIKAK SPARPHLENI
610 620 630 640 650
IKLYYVTNVL GPFIDEFLRF GVISPSVAKY ITTEYPQKLC AAIRPYVIGL
660 670 680 690 700
TDSFQQPDNF INSLIGRYDG NVYTNYLTNV TNVNDPTNYK APYSEALEAM
710 720
LNRASLEERE RFEKSKAVAA KLSQ
Length:724
Mass (Da):82,274
Last modified:November 1, 1996 - v1
Checksum:i6081C636926CEFC1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D21228 Genomic DNA. Translation: BAA04761.1.
PIRiJC4563.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D21228 Genomic DNA. Translation: BAA04761.1 .
PIRi JC4563.

3D structure databases

ProteinModelPortali Q00468.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Enzyme and pathway databases

UniPathwayi UPA00661 .

Family and domain databases

Gene3Di 1.10.540.10. 1 hit.
2.40.110.10. 1 hit.
InterProi IPR029320. Acyl-CoA_ox_N.
IPR006091. Acyl-CoA_Oxase/DH_cen-dom.
IPR012258. Acyl-CoA_oxidase.
IPR002655. Acyl-CoA_oxidase_C.
IPR009075. AcylCo_DH/oxidase_C.
IPR013786. AcylCoA_DH/ox_N.
IPR009100. AcylCoA_DH/oxidase_NM_dom.
[Graphical view ]
Pfami PF01756. ACOX. 1 hit.
PF02770. Acyl-CoA_dh_M. 1 hit.
PF14749. Acyl-CoA_ox_N. 1 hit.
[Graphical view ]
PIRSFi PIRSF000168. Acyl-CoA_oxidase. 1 hit.
SUPFAMi SSF47203. SSF47203. 2 hits.
SSF56645. SSF56645. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Cloning and characterization of the POX2 gene in Candida maltosa."
    Masuda Y., Park S.M., Ohta A., Takagi M.
    Gene 167:157-161(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 28140 / CBS 5611 / IAM 12247 / JCM 1504 / NBRC 1977.

Entry informationi

Entry nameiACOX2_CANMA
AccessioniPrimary (citable) accession number: Q00468
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1996
Last modified: November 26, 2014
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3