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Q00468

- ACOX2_CANMA

UniProt

Q00468 - ACOX2_CANMA

Protein

Acyl-coenzyme A oxidase 2

Gene

POX2

Organism
Candida maltosa (Yeast)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 76 (01 Oct 2014)
      Sequence version 1 (01 Nov 1996)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    Acyl-CoA + O2 = trans-2,3-dehydroacyl-CoA + H2O2.

    Cofactori

    FAD.

    Pathwayi

    GO - Molecular functioni

    1. acyl-CoA dehydrogenase activity Source: InterPro
    2. acyl-CoA oxidase activity Source: UniProtKB-EC
    3. flavin adenine dinucleotide binding Source: InterPro

    GO - Biological processi

    1. fatty acid beta-oxidation using acyl-CoA oxidase Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Oxidoreductase

    Keywords - Biological processi

    Fatty acid metabolism, Lipid metabolism

    Keywords - Ligandi

    FAD, Flavoprotein

    Enzyme and pathway databases

    UniPathwayiUPA00661.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Acyl-coenzyme A oxidase 2 (EC:1.3.3.6)
    Short name:
    AOX 2
    Short name:
    Acyl-CoA oxidase 2
    Gene namesi
    Name:POX2
    OrganismiCandida maltosa (Yeast)
    Taxonomic identifieri5479 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesmitosporic SaccharomycetalesCandida

    Subcellular locationi

    GO - Cellular componenti

    1. peroxisome Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Peroxisome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 724724Acyl-coenzyme A oxidase 2PRO_0000204693Add
    BLAST

    Structurei

    3D structure databases

    ProteinModelPortaliQ00468.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the acyl-CoA oxidase family.Curated

    Family and domain databases

    Gene3Di1.10.540.10. 1 hit.
    2.40.110.10. 1 hit.
    InterProiIPR029320. Acyl-CoA_ox_N.
    IPR006091. Acyl-CoA_Oxase/DH_cen-dom.
    IPR012258. Acyl-CoA_oxidase.
    IPR002655. Acyl-CoA_oxidase_C.
    IPR009075. AcylCo_DH/oxidase_C.
    IPR013786. AcylCoA_DH/ox_N.
    IPR009100. AcylCoA_DH/oxidase_NM_dom.
    [Graphical view]
    PfamiPF01756. ACOX. 1 hit.
    PF02770. Acyl-CoA_dh_M. 1 hit.
    PF14749. Acyl-CoA_ox_N. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000168. Acyl-CoA_oxidase. 1 hit.
    SUPFAMiSSF47203. SSF47203. 2 hits.
    SSF56645. SSF56645. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q00468-1 [UniParc]FASTAAdd to Basket

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    MALISNLKDE YDHPTKTDPD TNPKIVADII SSKEPPQPSQ DVAEERSRTD    50
    WDLKEMHEFL EGDEAKSEEI LRLYQSIERD PILQTRPEQF DYTKNEERES 100
    VALRINQMSK YLETEPYEKF RRRLQLMTVN DPSLGIRMLV NIGLFLNCIR 150
    GNGTQKQYDF WAKTKEAGKV KQLLRLFRYD ELGHGFNVAG CEIFATFDEK 200
    TDQFIIDTPH IGATKWWIGG AAHSATHTVC YARLIVKDID YGVKTFVVPL 250
    RDSTHNLLPG VAIGDIGPKL GRQGVDNGWI QFTEVRIPRF FMLQRWCKVD 300
    RQGNVTLPPL EQLSYISLLE GRVGMATDSY RIGARYTTIA LRYAVARRQF 350
    SKGDGQPETK LIDYTLHQRR LLPYLALTYL AALGTDKLER QHDQLLKNLD 400
    KALATNNKLL LKNTIQSTKS MFVDSGSLKS TLTWLASDLI NEARQSCGGH 450
    GYSAYNGFGK TYGDWAVQCT WEGDNNVLGM SAGKTIIKTV QQVLNGKQLK 500
    DSTLEFLNDA PALSSAKKAV IRIKSHVDDT DRVLKAIAGL ISKYAKDLIP 550
    VSYQSWDSIG PQRVVLSKFR CHYYLLETFN ERLNDRIKAK SPARPHLENI 600
    IKLYYVTNVL GPFIDEFLRF GVISPSVAKY ITTEYPQKLC AAIRPYVIGL 650
    TDSFQQPDNF INSLIGRYDG NVYTNYLTNV TNVNDPTNYK APYSEALEAM 700
    LNRASLEERE RFEKSKAVAA KLSQ 724
    Length:724
    Mass (Da):82,274
    Last modified:November 1, 1996 - v1
    Checksum:i6081C636926CEFC1
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    D21228 Genomic DNA. Translation: BAA04761.1.
    PIRiJC4563.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    D21228 Genomic DNA. Translation: BAA04761.1 .
    PIRi JC4563.

    3D structure databases

    ProteinModelPortali Q00468.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Enzyme and pathway databases

    UniPathwayi UPA00661 .

    Family and domain databases

    Gene3Di 1.10.540.10. 1 hit.
    2.40.110.10. 1 hit.
    InterProi IPR029320. Acyl-CoA_ox_N.
    IPR006091. Acyl-CoA_Oxase/DH_cen-dom.
    IPR012258. Acyl-CoA_oxidase.
    IPR002655. Acyl-CoA_oxidase_C.
    IPR009075. AcylCo_DH/oxidase_C.
    IPR013786. AcylCoA_DH/ox_N.
    IPR009100. AcylCoA_DH/oxidase_NM_dom.
    [Graphical view ]
    Pfami PF01756. ACOX. 1 hit.
    PF02770. Acyl-CoA_dh_M. 1 hit.
    PF14749. Acyl-CoA_ox_N. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000168. Acyl-CoA_oxidase. 1 hit.
    SUPFAMi SSF47203. SSF47203. 2 hits.
    SSF56645. SSF56645. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Cloning and characterization of the POX2 gene in Candida maltosa."
      Masuda Y., Park S.M., Ohta A., Takagi M.
      Gene 167:157-161(1995) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: ATCC 28140 / CBS 5611 / IAM 12247 / JCM 1504 / NBRC 1977.

    Entry informationi

    Entry nameiACOX2_CANMA
    AccessioniPrimary (citable) accession number: Q00468
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 1, 1997
    Last sequence update: November 1, 1996
    Last modified: October 1, 2014
    This is version 76 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3