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Protein

Homeobox-leucine zipper protein HAT7

Gene

HAT7

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Probable transcription factor.By similarity

Caution

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi112 – 171HomeoboxPROSITE-ProRule annotationAdd BLAST60

GO - Molecular functioni

  • DNA binding Source: TAIR
  • DNA binding transcription factor activity Source: TAIR
  • sequence-specific DNA binding Source: TAIR

GO - Biological processi

Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
Homeobox-leucine zipper protein HAT7
Alternative name(s):
HD-ZIP protein ATHB-3
Homeodomain transcription factor ATHB-3
Homeodomain-leucine zipper protein HAT7
Short name:
HD-ZIP protein 7
Gene namesi
Name:HAT7
Synonyms:ATHB-3
Ordered Locus Names:At5g15150
ORF Names:F8M21_40
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 5

Organism-specific databases

AraportiAT5G15150
TAIRilocus:2150901 AT5G15150

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000489031 – 314Homeobox-leucine zipper protein HAT7Add BLAST314

Proteomic databases

PaxDbiQ00466

Expressioni

Tissue specificityi

Expressed predominantly in flowers, and in the cortex of the root and the stem.1 Publication

Gene expression databases

ExpressionAtlasiQ00466 baseline and differential
GenevisibleiQ00466 AT

Interactioni

Protein-protein interaction databases

STRINGi3702.AT5G15150.1

Structurei

3D structure databases

ProteinModelPortaliQ00466
SMRiQ00466
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni172 – 207Leucine-zipperAdd BLAST36

Sequence similaritiesi

Keywords - Domaini

Homeobox

Phylogenomic databases

eggNOGiKOG0483 Eukaryota
ENOG410Z2UE LUCA
HOGENOMiHOG000006025
InParanoidiQ00466
KOiK09338
OMAiEEQQGFW
OrthoDBiEOG09360GTY
PhylomeDBiQ00466

Family and domain databases

CDDicd00086 homeodomain, 1 hit
InterProiView protein in InterPro
IPR009057 Homeobox-like_sf
IPR017970 Homeobox_CS
IPR001356 Homeobox_dom
IPR000047 HTH_motif
IPR003106 Leu_zip_homeo
PfamiView protein in Pfam
PF02183 HALZ, 1 hit
PF00046 Homeobox, 1 hit
PRINTSiPR00031 HTHREPRESSR
SMARTiView protein in SMART
SM00389 HOX, 1 hit
SUPFAMiSSF46689 SSF46689, 1 hit
PROSITEiView protein in PROSITE
PS00027 HOMEOBOX_1, 1 hit
PS50071 HOMEOBOX_2, 1 hit

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform 1 (identifier: Q00466-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MYMYEEERNN INNNQEGLRL EMAFPQHGFM FQQLHEDNAH HLPSPTSLPS
60 70 80 90 100
CPPHLFYGGG GNYMMNRSMS FTGVSDHHHL TQKSPTTTNN MNDQDQVGEE
110 120 130 140 150
DNLSDDGSHM MLGEKKKRLN LEQVRALEKS FELGNKLEPE RKMQLAKALG
160 170 180 190 200
LQPRQIAIWF QNRRARWKTK QLERDYDSLK KQFDVLKSDN DSLLAHNKKL
210 220 230 240 250
HAELVALKKH DRKESAKIKR EFAEASWSNN GSTENNHNNN SSDANHVSMI
260 270 280 290 300
KDLFPSSIRS ATATTTSTHI DHQIVQDQDQ GFCNMFNGID ETTSASYWAW
310
PDQQQQHHNH HQFN
Length:314
Mass (Da):36,282
Last modified:May 10, 2005 - v4
Checksum:i8DAC95F6DCD11F8B
GO
Isoform 2 (identifier: Q00466-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-63: Missing.
     204-214: LVALKKHDRKE → VYNIHTNSTNR
     215-314: Missing.

Note: May be due to intron retention. No experimental confirmation available.
Show »
Length:151
Mass (Da):17,647
Checksum:i03C9C21EB94E0B81
GO

Sequence cautioni

The sequence AAA56906 differs from that shown. Reason: Erroneous initiation.Curated
The sequence CAB89325 differs from that shown. Reason: Erroneous gene model prediction.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti78H → L in CAA44513 (PubMed:1349836).Curated1
Sequence conflicti78H → Y in AAA56906 (PubMed:7915839).Curated1
Sequence conflicti266T → A in AAA56906 (PubMed:7915839).Curated1
Sequence conflicti273Q → E in AAA56906 (PubMed:7915839).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_0136471 – 63Missing in isoform 2. 1 PublicationAdd BLAST63
Alternative sequenceiVSP_013648204 – 214LVALKKHDRKE → VYNIHTNSTNR in isoform 2. 1 PublicationAdd BLAST11
Alternative sequenceiVSP_013649215 – 314Missing in isoform 2. 1 PublicationAdd BLAST100

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X62644 mRNA Translation: CAA44513.1
AL353993 Genomic DNA Translation: CAB89325.1 Sequence problems.
CP002688 Genomic DNA Translation: AED92122.1
AK229364 mRNA Translation: BAF01227.1
U09340 mRNA Translation: AAA56906.1 Different initiation.
PIRiS20930
T49950
T52370
RefSeqiNP_568309.2, NM_121519.3 [Q00466-1]
UniGeneiAt.49022

Genome annotation databases

EnsemblPlantsiAT5G15150.1; AT5G15150.1; AT5G15150 [Q00466-1]
GeneIDi831367
GrameneiAT5G15150.1; AT5G15150.1; AT5G15150 [Q00466-1]
KEGGiath:AT5G15150

Keywords - Coding sequence diversityi

Alternative splicing

Similar proteinsi

Entry informationi

Entry nameiHAT7_ARATH
AccessioniPrimary (citable) accession number: Q00466
Secondary accession number(s): Q0WNS2, Q9LXG6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 1, 1993
Last sequence update: May 10, 2005
Last modified: April 25, 2018
This is version 143 of the entry and version 4 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome