Q00391 (FRHB_METVO) Reviewed, UniProtKB/Swiss-Prot
Last modified
June 28, 2011.
Version 46.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: Coenzyme F420 hydrogenase subunit beta EC=1.12.98.1 Alternative name(s): 8-hydroxy-5-deazaflavin-reducing hydrogenase subunit beta Short name=FRH | ||||
| Gene names |
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| Organism | Methanococcus voltae | ||||
| Taxonomic identifier | 2188 [NCBI] | ||||
| Taxonomic lineage | Archaea › Euryarchaeota › Methanococci › Methanococcales › Methanococcaceae › Methanococcus |
Protein attributes
| Sequence length | 280 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology |
General annotation (Comments)
| Function | Reduces the physiological low-potential two-electron acceptor coenzyme F420, and the artificial one-electron acceptor methylviologen. |
| Catalytic activity | H2 + coenzyme F420 = reduced coenzyme F420. |
| Cofactor | Nickel. Iron-sulfur. FAD. |
| Subunit structure | Complex of alpha, beta and gamma subunits. |
| Sequence similarities | Belongs to the frhB family. |
Ontologies
| Keywords | |
|---|---|
| Ligand | Iron Iron-sulfur Metal-binding |
| Molecular function | Oxidoreductase |
| Gene Ontology (GO) | |
| Molecular function | coenzyme F420 hydrogenase activity Inferred from electronic annotation. Source: EC flavin adenine dinucleotide bindingInferred from electronic annotation. Source: InterPro iron-sulfur cluster bindingInferred from electronic annotation. Source: UniProtKB-KW nickel cation bindingInferred from electronic annotation. Source: InterPro |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||
Molecule processing | |||||||
|---|---|---|---|---|---|---|---|
| Chain | 1 – 280 | 280 | Coenzyme F420 hydrogenase subunit beta | PRO_0000159230 | |||
Sequences
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References
| [1] | "Methanococcus voltae harbors four gene clusters potentially encoding two [NiFe] and two [NiFeSe] hydrogenases, each of the cofactor F420-reducing or F420-non-reducing types." Halboth S., Klein A. Mol. Gen. Genet. 233:217-224(1992) [PubMed: 1603063] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 33273 / DSM 1537 / NBRC 100457 / OCM 70 / PS. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | X61201 Genomic DNA. Translation: CAA43499.1. |
| PIR | S16724. |
3D structure databases | |
| ModBase | Search... |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Family and domain databases | |
| InterPro | IPR007516. Co_F420_Hydgase/DH_bsu_N. IPR017679. Coenz_F420_hydrogenase_bsu. IPR007525. FrhB_FdhB_C. [Graphical view] |
| Pfam | PF04432. FrhB_FdhB_C. 1 hit. PF04422. FrhB_FdhB_N. 1 hit. [Graphical view] |
| TIGRFAMs | TIGR03289. FrhB. 1 hit. |
| ProtoNet | Search... |
Entry information
| Entry name | FRHB_METVO | ||||||||
| Accession | Primary (citable) accession number: Q00391 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Prokaryotic Protein Annotation Program | ||||||||
Relevant documents
| SIMILARITY comments Index of protein domains and families |

Clusters with