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Reviewed, UniProtKB/Swiss-Prot Q00391 (FRHB_METVO)

Last modified November 4, 2008. Version 36. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Coenzyme F420 hydrogenase subunit beta
    EC=1.12.98.1
Alternative name(s):
    8-hydroxy-5-deazaflavin-reducing hydrogenase subunit beta
      Short name=FRH
Gene names
Name: frhB
Synonyms: frcB
OrganismMethanococcus voltae
Taxonomic identifier2188 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaMethanococciMethanococcalesMethanococcaceaeMethanococcus

Protein attributes

Sequence length280 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

General annotation (Comments)

Function

Reduces the physiological low-potential two-electron acceptor coenzyme F420, and the artificial one-electron acceptor methylviologen.

Catalytic activity

H(2) + coenzyme F420 = reduced coenzyme F420.

Cofactor

Nickel.

Iron-sulfur.

FAD.

Subunit structure

Complex of alpha, beta and gamma subunits.

Sequence similarities

Belongs to the frhB family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 280280Coenzyme F420 hydrogenase subunit beta
PRO_0000159230

Sequences

Sequence LengthMass (Da)Tools
Q00391-1 [UniParc].

Last modified October 1, 1996. Version 1.
Checksum: CA00DC1F6DAE46AA

FASTA28030,868
        10         20         30         40         50         60 
MPFGNYKTAI SARATDKEIL KKAQDGGYVS AAHIYGLESK LLDGVSVAAD TEDGCNAAPK 

        70         80         90        100        110        120 
VATTPEEVLN AAGAKYTVSP NVSVLKDAVR EYALEKVGIV GTPCQVQAIR KLIKYPMGFR 

       130        140        150        160        170        180 
HTDSRIVMGI FCMENFSYEG MKAIVEEYAG IRMDDVLKTD IGKGKFWVYS KYGDVKSVKL 

       190        200        210        220        230        240 
KDTHMYEQKS CHICTDYTAE LADISTGSVG SPDGWSTIFI RTEKGEAYIN KMVEAGVLET 

       250        260        270        280 
KNIDDVKPGL DLVQKLSLQK KEKNEKEIVQ RRELGLPVPY 

« Hide

References

[1]"Methanococcus voltae harbors four gene clusters potentially encoding two [NiFe] and two [NiFeSe] hydrogenases, each of the cofactor F420-reducing or F420-non-reducing types."
Halboth S., Klein A.
Mol. Gen. Genet. 233:217-224(1992) [PubMed: 1603063] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: DSM 1537 / PS.

Cross-references

Sequence databases

X61201 Genomic DNA. Translation: CAA43499.1.
PIRS16724.

3D structure databases

ModBaseSearch...

Family and domain databases

InterProIPR007516. Co_F420_Hydgase/DHase_bsu_N.
IPR017679. Coenz_F4210_hydrogenase_bsu.
IPR007525. FrhB_FdhB_C.
[Graphical view]
PfamPF04432. FrhB_FdhB_C. 1 hit.
PF04422. FrhB_FdhB_N. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameFRHB_METVO
AccessionPrimary (citable) accession number: Q00391
Entry history
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: November 4, 2008
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents