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Protein

Polyferredoxin protein VhuB

Gene

vhuB

Organism
Methanococcus voltae
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Cofactori

[4Fe-4S] clusterCuratedNote: Binds 12 [4Fe-4S] clusters.Curated

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi11 – 111Iron-sulfur (4Fe-4S)Sequence analysis
Metal bindingi14 – 141Iron-sulfur (4Fe-4S)Sequence analysis
Metal bindingi17 – 171Iron-sulfur (4Fe-4S)Sequence analysis
Metal bindingi21 – 211Iron-sulfur (4Fe-4S)Sequence analysis
Metal bindingi34 – 341Iron-sulfur (4Fe-4S)Sequence analysis
Metal bindingi37 – 371Iron-sulfur (4Fe-4S)Sequence analysis
Metal bindingi40 – 401Iron-sulfur (4Fe-4S)Sequence analysis
Metal bindingi44 – 441Iron-sulfur (4Fe-4S)Sequence analysis
Metal bindingi63 – 631Iron-sulfur (4Fe-4S)Sequence analysis
Metal bindingi66 – 661Iron-sulfur (4Fe-4S)Sequence analysis
Metal bindingi69 – 691Iron-sulfur (4Fe-4S)Sequence analysis
Metal bindingi73 – 731Iron-sulfur (4Fe-4S)Sequence analysis
Metal bindingi91 – 911Iron-sulfur (4Fe-4S)Sequence analysis
Metal bindingi94 – 941Iron-sulfur (4Fe-4S)Sequence analysis
Metal bindingi97 – 971Iron-sulfur (4Fe-4S)Sequence analysis
Metal bindingi101 – 1011Iron-sulfur (4Fe-4S)Sequence analysis
Metal bindingi132 – 1321Iron-sulfur (4Fe-4S)Sequence analysis
Metal bindingi135 – 1351Iron-sulfur (4Fe-4S)Sequence analysis
Metal bindingi138 – 1381Iron-sulfur (4Fe-4S)Sequence analysis
Metal bindingi142 – 1421Iron-sulfur (4Fe-4S)Sequence analysis
Metal bindingi161 – 1611Iron-sulfur (4Fe-4S)Sequence analysis
Metal bindingi164 – 1641Iron-sulfur (4Fe-4S)Sequence analysis
Metal bindingi167 – 1671Iron-sulfur (4Fe-4S)Sequence analysis
Metal bindingi171 – 1711Iron-sulfur (4Fe-4S)Sequence analysis
Metal bindingi199 – 1991Iron-sulfur (4Fe-4S)Sequence analysis
Metal bindingi202 – 2021Iron-sulfur (4Fe-4S)Sequence analysis
Metal bindingi205 – 2051Iron-sulfur (4Fe-4S)Sequence analysis
Metal bindingi209 – 2091Iron-sulfur (4Fe-4S)Sequence analysis
Metal bindingi229 – 2291Iron-sulfur (4Fe-4S)Sequence analysis
Metal bindingi232 – 2321Iron-sulfur (4Fe-4S)Sequence analysis
Metal bindingi235 – 2351Iron-sulfur (4Fe-4S)Sequence analysis
Metal bindingi239 – 2391Iron-sulfur (4Fe-4S)Sequence analysis
Metal bindingi268 – 2681Iron-sulfur (4Fe-4S)Sequence analysis
Metal bindingi271 – 2711Iron-sulfur (4Fe-4S)Sequence analysis
Metal bindingi274 – 2741Iron-sulfur (4Fe-4S)Sequence analysis
Metal bindingi278 – 2781Iron-sulfur (4Fe-4S)Sequence analysis
Metal bindingi311 – 3111Iron-sulfur (4Fe-4S)Sequence analysis
Metal bindingi314 – 3141Iron-sulfur (4Fe-4S)Sequence analysis
Metal bindingi317 – 3171Iron-sulfur (4Fe-4S)Sequence analysis
Metal bindingi321 – 3211Iron-sulfur (4Fe-4S)Sequence analysis
Metal bindingi348 – 3481Iron-sulfur (4Fe-4S)Sequence analysis
Metal bindingi351 – 3511Iron-sulfur (4Fe-4S)Sequence analysis
Metal bindingi354 – 3541Iron-sulfur (4Fe-4S)Sequence analysis
Metal bindingi358 – 3581Iron-sulfur (4Fe-4S)Sequence analysis
Metal bindingi377 – 3771Iron-sulfur (4Fe-4S)Sequence analysis
Metal bindingi380 – 3801Iron-sulfur (4Fe-4S)Sequence analysis
Metal bindingi383 – 3831Iron-sulfur (4Fe-4S)Sequence analysis
Metal bindingi387 – 3871Iron-sulfur (4Fe-4S)Sequence analysis

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Electron transport, Transport

Keywords - Ligandi

4Fe-4S, Iron, Iron-sulfur, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Polyferredoxin protein VhuB
Gene namesi
Name:vhuB
OrganismiMethanococcus voltae
Taxonomic identifieri2188 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanococciMethanococcalesMethanococcaceaeMethanococcus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 398398Polyferredoxin protein VhuBPRO_0000159147Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliQ00388.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini2 – 31304Fe-4S ferredoxin-type 1PROSITE-ProRule annotationAdd
BLAST
Domaini25 – 53294Fe-4S ferredoxin-type 2PROSITE-ProRule annotationAdd
BLAST
Domaini54 – 83304Fe-4S ferredoxin-type 3PROSITE-ProRule annotationAdd
BLAST
Domaini82 – 111304Fe-4S ferredoxin-type 4PROSITE-ProRule annotationAdd
BLAST
Domaini123 – 152304Fe-4S ferredoxin-type 5PROSITE-ProRule annotationAdd
BLAST
Domaini152 – 181304Fe-4S ferredoxin-type 6PROSITE-ProRule annotationAdd
BLAST
Domaini191 – 219294Fe-4S ferredoxin-type 7PROSITE-ProRule annotationAdd
BLAST
Domaini220 – 249304Fe-4S ferredoxin-type 8PROSITE-ProRule annotationAdd
BLAST
Domaini259 – 291334Fe-4S ferredoxin-type 9PROSITE-ProRule annotationAdd
BLAST
Domaini300 – 331324Fe-4S ferredoxin-type 10PROSITE-ProRule annotationAdd
BLAST
Domaini339 – 368304Fe-4S ferredoxin-type 11PROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 11 4Fe-4S ferredoxin-type domains.PROSITE-ProRule annotation

Keywords - Domaini

Repeat

Family and domain databases

InterProiIPR017896. 4Fe4S_Fe-S-bd.
IPR017900. 4Fe4S_Fe_S_CS.
[Graphical view]
PfamiPF00037. Fer4. 1 hit.
PF12838. Fer4_7. 2 hits.
PF13187. Fer4_9. 1 hit.
[Graphical view]
PROSITEiPS00198. 4FE4S_FER_1. 11 hits.
PS51379. 4FE4S_FER_2. 11 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q00388-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAGIKIQEDA CLVCNACSKA CPTEAIEIAP FKTCTLCFSC ASACPTGALV
60 70 80 90 100
ENNGKLIYNS SKCIKCGNCA TACPTGIKKV DDRFPYSKGH CVLCEKCVDA
110 120 130 140 150
CPIDIISIPG KIDKPEREVT IPQEPIKVTE ACVGCSECVP VCPVDAISIE
160 170 180 190 200
DELAVIDTEK CIYCSVCAQT CPWNAIYVAG KKPSKRQKEI KSFTVTEECI
210 220 230 240 250
GCEKCVEVCP GDMITYNRED LIVKLPEACP ACHLCEQNCP VDAISLEVEY
260 270 280 290 300
GSAKPVTEEG LVWYEDKCNY CGPCAIKCPL CPTNAINMIN QKGLALPSRT
310 320 330 340 350
KTDKDPEFRM CIRCGACVMK CPTGALKMGK ITHEGKEYNR IEFSPALCNE
360 370 380 390
CGECVDVCPQ DTLKLTGDEK KPLEGYCILC LKCIEACAKT KRNALGLQ
Length:398
Mass (Da):43,188
Last modified:January 1, 1998 - v2
Checksum:i2602FBECCAC366D3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X61204 Genomic DNA. Translation: CAA43512.1.
PIRiS24802.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X61204 Genomic DNA. Translation: CAA43512.1.
PIRiS24802.

3D structure databases

ProteinModelPortaliQ00388.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

InterProiIPR017896. 4Fe4S_Fe-S-bd.
IPR017900. 4Fe4S_Fe_S_CS.
[Graphical view]
PfamiPF00037. Fer4. 1 hit.
PF12838. Fer4_7. 2 hits.
PF13187. Fer4_9. 1 hit.
[Graphical view]
PROSITEiPS00198. 4FE4S_FER_1. 11 hits.
PS51379. 4FE4S_FER_2. 11 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Methanococcus voltae harbors four gene clusters potentially encoding two [NiFe] and two [NiFeSe] hydrogenases, each of the cofactor F420-reducing or F420-non-reducing types."
    Halboth S., Klein A.
    Mol. Gen. Genet. 233:217-224(1992) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 33273 / DSM 1537 / NBRC 100457 / OCM 70 / PS.

Entry informationi

Entry nameiVHUB_METVO
AccessioniPrimary (citable) accession number: Q00388
Secondary accession number(s): P95320
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 16, 2004
Last sequence update: January 1, 1998
Last modified: May 11, 2016
This is version 72 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.