Q00310 (KRE2_CANAL) Reviewed, UniProtKB/Swiss-Prot
Last modified
January 25, 2012.
Version 73.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: Glycolipid 2-alpha-mannosyltransferase EC=2.4.1.- Alternative name(s): Alpha-1,2-mannosyltransferase | ||||||
| Gene names |
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| Organism | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | ||||||
| Taxonomic identifier | 237561 [NCBI] | ||||||
| Taxonomic lineage | Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › mitosporic Saccharomycetales › Candida |
Protein attributes
| Sequence length | 431 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology |
General annotation (Comments)
| Function | Required for the attachment of the third mannose residue of O-linked saccharides By similarity. |
| Catalytic activity | Transfers an alpha-D-mannosyl residue from GDP-mannose into lipid-linked oligosaccharide, forming an alpha-(1->2)-D-mannosyl-D-mannose linkage. |
| Pathway | |
| Subcellular location | Golgi apparatus membrane; Single-pass type II membrane protein Potential. |
| Sequence similarities | Belongs to the glycosyltransferase 15 family. |
Ontologies
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 431 | 431 | Glycolipid 2-alpha-mannosyltransferase | PRO_0000208240 | |||||
Regions | |||||||||
| Topological domain | 1 – 9 | 9 | Cytoplasmic Potential | ||||||
| Transmembrane | 10 – 28 | 19 | Helical; Signal-anchor for type II membrane protein; Potential | ||||||
| Topological domain | 29 – 431 | 403 | Lumenal Potential | ||||||
Sites | |||||||||
| Active site | 318 | 1 | Nucleophile Potential | ||||||
Sequences
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References
| « Hide 'large scale' references | |
| [1] | "Molecular analysis of CaMnt1p, a mannosyl transferase important for adhesion and virulence of Candida albicans." Buurman E.T., Westwater C., Hube B., Brown A.J., Odds F.C., Gow N.A.R. Proc. Natl. Acad. Sci. U.S.A. 95:7670-7675(1998) [PubMed: 9636208] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: CAI4. |
| [2] | "The diploid genome sequence of Candida albicans." Jones T., Federspiel N.A., Chibana H., Dungan J., Kalman S., Magee B.B., Newport G., Thorstenson Y.R., Agabian N., Magee P.T., Davis R.W., Scherer S. Proc. Natl. Acad. Sci. U.S.A. 101:7329-7334(2004) [PubMed: 15123810] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: SC5314 / ATCC MYA-2876. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | X99619 Genomic DNA. Translation: CAA67930.1. AACQ01000014 Genomic DNA. Translation: EAL02827.1. AACQ01000013 Genomic DNA. Translation: EAL02954.1. |
| RefSeq | XP_721623.1. XM_716530.1. XP_721742.1. XM_716649.1. |
3D structure databases | |
| ProteinModelPortal | Q00310. |
| SMR | Q00310. Positions 101-429. |
| ModBase | Search... |
Protein family/group databases | |
| CAZy | GT15. Glycosyltransferase Family 15. |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| GeneID | 3636585. 3636767. |
| KEGG | cal:CaO19.1665. cal:CaO19.9234. |
Organism-specific databases | |
| CGD | CAL0000071. MNT1. |
Phylogenomic databases | |
| OMA | EYKETIP. |
| PhylomeDB | Q00310. |
Family and domain databases | |
| InterPro | IPR002685. Glyco_trans_15. [Graphical view] |
| KO | K10967. |
| Pfam | PF01793. Glyco_transf_15. 1 hit. [Graphical view] |
| PIRSF | PIRSF018153. Glyco_trans_15. 1 hit. |
| ProtoNet | Search... |
Entry information
| Entry name | KRE2_CANAL | ||||||||
| Accession | Primary (citable) accession number: Q00310 Secondary accession number(s): Q5AJC6 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Fungal Protein Annotation Program | ||||||||
Relevant documents
| Candida albicans Candida albicans: entries and gene names |
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

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