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Protein

Protein kinase ORF74

Gene

ORF74

Organism
Ictalurid herpesvirus 1 (strain Auburn) (IcHV-1) (Channel catfish herpesvirus)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei252Proton acceptorPROSITE-ProRule annotation1

GO - Molecular functioni

Keywordsi

Molecular functionKinase, Serine/threonine-protein kinase, Transferase
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Protein kinase ORF74 (EC:2.7.11.1)
Gene namesi
Name:ORF74
OrganismiIctalurid herpesvirus 1 (strain Auburn) (IcHV-1) (Channel catfish herpesvirus)
Taxonomic identifieri766178 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stageHerpesviralesAlloherpesviridaeIctalurivirus
Virus hostiIctaluridae (bullhead catfishes) [TaxID: 7996]
Proteomesi
  • UP000007643 Componenti: Genome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000861911 – 673Protein kinase ORF74Add BLAST673

Proteomic databases

PRIDEiQ00095.

Structurei

3D structure databases

ProteinModelPortaliQ00095.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini128 – 404Protein kinasePROSITE-ProRule annotationAdd BLAST277

Sequence similaritiesi

Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.PROSITE-ProRule annotation

Phylogenomic databases

OrthoDBiVOG090000QN.

Family and domain databases

InterProiView protein in InterPro
IPR011009. Kinase-like_dom_sf.
IPR000719. Prot_kinase_dom.
PfamiView protein in Pfam
PF00069. Pkinase. 1 hit.
SMARTiView protein in SMART
SM00220. S_TKc. 1 hit.
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiView protein in PROSITE
PS50011. PROTEIN_KINASE_DOM. 1 hit.

Sequencei

Sequence statusi: Complete.

Q00095-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSGKVEINEP LIVATSAPLR CNCTGGSHFH GKTIANRALG SSQLMKCYSG
60 70 80 90 100
LLKRCVRREK YIPVSDRGFL DAYTPQTAPG IVFTGSSLVT DSTLMMAPFN
110 120 130 140 150
FHRQHVLPLE ENFGLERARG DVTVDIRTDT DEAVARGLRS DMYERDAVGH
160 170 180 190 200
IVSKPQKRTT GEMLDELMMT ARLSHGNLVR FLGGVACEET RGGKITVKMV
210 220 230 240 250
ELGLCNLDEF IAEPHWIAPK FAIVRQYTLC KLERDTLSGL EYLHMHGVVH
260 270 280 290 300
GDFRGAKVIV FPTADDFTFK VNLGESTSLG IAPALSRAPY HRAPETEFTG
310 320 330 340 350
LIGREADMWA WALTMYRAHT CKDFFKKGDP SEPYRVLGPM DNDALDSRRT
360 370 380 390 400
GRDGDPVNPE GFGTRLEKNA TAVDGGFIGL MGKCLALYPQ FRPTARELLV
410 420 430 440 450
YPRYATLHRI SGPGPAPPPV IGAAPAVRVV SNAVEFRSRW GVRPSPAMDP
460 470 480 490 500
RLEARTSWGK NAVRAVGDFT PSFLYREGGL GDTRPGNKRA ITLSRGTLRS
510 520 530 540 550
YVGTENRLTT EIHRSGGADI VLHKVVGRRP DISRANLEYV MKVSNGFPEW
560 570 580 590 600
YITIDHYTVG VTNVHLYVGY ITDDIVYASA IGLSCPLRVD ILKGFEKSTL
610 620 630 640 650
RVDLMGILVT RGLAYTLRVI RHLKSASIYE AGPHAVGLVF VNPSSRNRFG
660 670
TVSCDSVKLE LGDEPSQLIT GSR
Length:673
Mass (Da):74,133
Last modified:December 1, 1992 - v1
Checksum:iC59466DA3A112FE8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M75136 Genomic DNA. Translation: AAA88176.1.
PIRiI36793. TVBEI5.
RefSeqiNP_041164.1. NC_001493.2.

Genome annotation databases

GeneIDi1488364.
KEGGivg:1488364.

Entry informationi

Entry nameiKR74_ICHVA
AccessioniPrimary (citable) accession number: Q00095
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 1, 1992
Last sequence update: December 1, 1992
Last modified: November 22, 2017
This is version 78 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families