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Q00075 (TPSA_ASPNG) Reviewed, UniProtKB/Swiss-Prot

Last modified November 13, 2013. Version 56. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Alpha,alpha-trehalose-phosphate synthase [UDP-forming] 1

EC=2.4.1.15
Alternative name(s):
Trehalose-6-phosphate synthase
UDP-glucose-glucosephosphate glucosyltransferase
Gene names
Name:tpsA
Synonyms:tps1
OrganismAspergillus niger
Taxonomic identifier5061 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus

Protein attributes

Sequence length517 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

UDP-glucose + D-glucose 6-phosphate = UDP + alpha,alpha-trehalose 6-phosphate.

Sequence similarities

Belongs to the glycosyltransferase 20 family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 517517Alpha,alpha-trehalose-phosphate synthase [UDP-forming] 1
PRO_0000122494

Sequences

Sequence LengthMass (Da)Tools
Q00075 [UniParc].

Last modified November 1, 1997. Version 1.
Checksum: 8EF38ED40D66A1CC

FASTA51758,376
        10         20         30         40         50         60 
MPSLENPTFQ NEARLLLVSN RLPITIKRSD DGRYDFSMSS GGLVSGLSGL SKSTTFQWYG 

        70         80         90        100        110        120 
WPGLEVPEEE IPVVKERLKQ EYNAVPVFID DELADRHYNG FSNSILWPLF HYHPGEITFD 

       130        140        150        160        170        180 
ESAWEAYKEA NRLFAKAVAK EVQDGDLIWV HDYHLMLLPE MLREEIGDSK ENVKIGFFLH 

       190        200        210        220        230        240 
TPFPSSEIYR ILPVRNELLL GVLHCDLIGF HTYDYTRHFL SACSRLLGLT TTPNGIEFQG 

       250        260        270        280        290        300 
KIIACGAFPI GIDPEKFEEG LKKEKVQKRI AMLEQKFQGV KLMVGVDRLD YIKGVPQKLH 

       310        320        330        340        350        360 
ALEVFLSDHP EWVGKVVLVQ VAVPSRQDVE EYQNLRAVVN ELVGRINGKF GTVEFMPIHF 

       370        380        390        400        410        420 
LHKSVNFDEL IALYAVSDAC IVSSTRDGMN LVAYEYIATQ KKRHGVLVLS EFAGAAQSLN 

       430        440        450        460        470        480 
GSIIINPWNT EELAGAYQEA VTMSDEQRAL NFSKLDKYVN KYTSAFWGQS FVTELTRISE 

       490        500        510 
HSAEKFHAKK ASFSDNNSEN GEPSNGVETP AQEQVAQ 

« Hide

References

[1]"The filamentous fungus Aspergillus niger contains two 'differentially regulated' trehalose-6-phosphate synthase-encoding genes, tpsA and tpsB."
Wolschek M.F., Kubicek C.P.
J. Biol. Chem. 272:2729-2735(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 11414 / NRRL 2270 / VTT D-77050.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
U07184 Unassigned DNA. Translation: AAA21861.1.

3D structure databases

ProteinModelPortalQ00075.
ModBaseSearch...
MobiDBSearch...

Protein family/group databases

CAZyGT20. Glycosyltransferase Family 20.

Proteomic databases

PRIDEQ00075.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Phylogenomic databases

eggNOGCOG0380.

Family and domain databases

InterProIPR001830. Glyco_trans_20.
IPR012766. Trehalose_OtsA.
[Graphical view]
PfamPF00982. Glyco_transf_20. 1 hit.
[Graphical view]
TIGRFAMsTIGR02400. trehalose_OtsA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameTPSA_ASPNG
AccessionPrimary (citable) accession number: Q00075
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: November 13, 2013
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families