Reviewed, UniProtKB/Swiss-Prot Q00054 (GALT_LACHE)

Names and origin

Protein names

Recommended name:
    Galactose-1-phosphate uridylyltransferase
      Short name=Gal-1-P uridylyltransferase
    EC=2.7.7.12
Alternative name(s):
    UDP-glucose--hexose-1-phosphate uridylyltransferase

Gene names

Name:

galT

Organism

Lactobacillus helveticus

Taxonomic identifier

1587 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Lactobacillales › Lactobacillaceae › Lactobacillus

Protein attributes

Sequence length	488 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	UDP-glucose + alpha-D-galactose 1-phosphate = alpha-D-glucose 1-phosphate + UDP-galactose. HAMAP MF_00571
Pathway	Carbohydrate metabolism; galactose metabolism. HAMAP MF_00571
Subcellular location	Cytoplasm Potential HAMAP MF_00571.
Sequence similarities	Belongs to the galactose-1-phosphate uridylyltransferase type 2 family.

Ontologies

Keywords
Biological process	Carbohydrate metabolism Galactose metabolism
Cellular component	Cytoplasm
Molecular function	Nucleotidyltransferase Transferase
Gene Ontology (GO)
Biological process	galactose metabolic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	UDP-glucose:hexose-1-phosphate uridylyltransferase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 488	488	Galactose-1-phosphate uridylyltransferase HAMAP MF_00571		PRO_0000169907

Sequences

	Sequence		Length	Mass (Da)
	Q00054-1 [UniParc]. Last modified December 1, 1992. Version 1. Checksum: A4117D88D0A9C0A5	FASTA	488	55,607
	10 20 30 40 50 60 MKIIEKFADE VINSGAYEPL DRVYVINKIR ALVGDHDEEE ENDQPAAKQL VDLAVKNEKI 70 80 90 100 110 120 PDDITSREVL NDQLYDLATP TPSKTNSIFW QKMQKSSEEN TDWFYKLCED NNYVKKEAIA 130 140 150 160 170 180 KNVVFSGTSS KGHSLEITIN LSKPEKDPKA IAAAAHATGK KYPQCALCLE NEGYLGGYGK 190 200 210 220 230 240 NARSNLRIIR MNIAGRPWGF QYSPYAYFNE HCIFLDQKHI PMVINQQTLI NLVEIEKIFP 250 260 270 280 290 300 HYFVGSNADL PIVGGSMLAH EHYQGGRHTF PMMKAGIKKN IMFDSYPKVV AGIVDWPMSD 310 320 330 340 350 360 LRLTSDNSLD LIDLGSKIIK FWDNYSDTAR DIKAYEGETR HHTVTPIMHR EGKNFVLDLV 370 380 390 400 410 420 LRDNNTSEKY PLGIFHPHKQ LWHIKKENIG LIEVMGRAIL PGRLKSELEE VKKYWLGEDN 430 440 450 460 470 480 KMAASHKEWA DQVKAENEIS LDNVDQVMEQ SLVEVFEQVL QDAGVFKNNA DGEEGWDKFI TALTKEIK

References

[1]

"Galactose utilization in Lactobacillus helveticus: isolation and characterization of the galactokinase (galK) and galactose-1-phosphate uridyl transferase (galT) genes." Mollet B., Pilloud N. J. Bacteriol. 173:4464-4473(1991) [PubMed: 2066342] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 15009 / DSM 20075 / IFO 15019 / JCM 1120 / Lh12.

Cross-references

Sequence databases
EMBL GenBank DDBJ	X57248 Genomic DNA. Translation: CAA40526.1.
PIR	B47032.
3D structure databases
ModBase	Search...
Enzyme and pathway databases
BRENDA	2.7.7.12. 39238.
Family and domain databases
HAMAP	MF_00571. GalP_UDP_trans. [Tree]
InterPro	IPR000766. GalP_uridyl_Trfase_II. IPR005850. GalP_Utransf_C. IPR005849. GalP_Utransf_N. [Graphical view]
Pfam	PF02744. GalP_UDP_tr_C. 1 hit. PF01087. GalP_UDP_transf. 1 hit. [Graphical view]
PIRSF	PIRSF006005. GalT_BS. 1 hit.
PROSITE	PS01163. GAL_P_UDP_TRANSF_II. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GALT_LACHE

Accession

Primary (citable) accession number: Q00054

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 1, 1992
Last sequence update:	December 1, 1992
Last modified:	January 19, 2010
This is version 55 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)