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Q00033

- NSP1_ROTPC

UniProt

Q00033 - NSP1_ROTPC

Protein

Non-structural protein 1

Gene
N/A
Organism
Rotavirus C (strain Pig/United States/Cowden/1980) (RV-C)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 42 (01 Oct 2014)
      Sequence version 1 (01 Dec 1992)
      Previous versions | rss
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    Functioni

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Zinc fingeri39 – 6830Sequence AnalysisAdd
    BLAST

    GO - Molecular functioni

    1. metal ion binding Source: UniProtKB-KW
    2. RNA binding Source: UniProtKB-KW

    GO - Biological processi

    1. suppression by virus of host IRF3 activity Source: UniProtKB-KW
    2. suppression by virus of host IRF7 activity Source: UniProtKB-KW
    3. suppression by virus of host NF-kappaB transcription factor activity Source: UniProtKB-KW

    Keywords - Biological processi

    Host-virus interaction, Inhibition of host innate immune response by virus, Inhibition of host IRF3 by virus, Inhibition of host IRF7 by virus, Inhibition of host NF-kappa-B by virus, Inhibition of host RLR pathway by virus, Viral immunoevasion

    Keywords - Ligandi

    Metal-binding, RNA-binding, Zinc

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Non-structural protein 1
    Short name:
    NSP1
    Alternative name(s):
    NCVP2
    Non-structural RNA-binding protein 53
    Short name:
    NS53
    OrganismiRotavirus C (strain Pig/United States/Cowden/1980) (RV-C)
    Taxonomic identifieri10916 [NCBI]
    Taxonomic lineageiVirusesdsRNA virusesReoviridaeSedoreovirinaeRotavirus
    Virus hostiSus scrofa (Pig) [TaxID: 9823]
    ProteomesiUP000008175: Genome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 393393Non-structural protein 1PRO_0000149560Add
    BLAST

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni2 – 7776RNA-bindingBy similarityAdd
    BLAST

    Sequence similaritiesi

    Belongs to the rotavirus C NSP1 family.Curated

    Zinc finger

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Zinc fingeri39 – 6830Sequence AnalysisAdd
    BLAST

    Keywords - Domaini

    Zinc-finger

    Sequencei

    Sequence statusi: Complete.

    Q00033-1 [UniParc]FASTAAdd to Basket

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    MANSYREMLY WFGKTIDRNL PYVNTNGWRK QKGRKDGICL NCLDECKLYS    50
    CDHCGIKHKC GNCVLSECFL DVKNEFNKYR WLVFDEEPDQ AVLLQHWIMY 100
    KDYFLQKFNY RLATQAKILN MNKNQKFQLN EGRKRALSVP ITSQFLKFRL 150
    FGKIYIQFGT IMTNKIQPWL ELSTLKIGYL QLLNVERCSE LMATRGQFTT 200
    NVAKTACITE IKCRRPIYDN DCIIEAYLDK NDRGWKFAAI LGRRKIPVTQ 250
    KLAMEYFMKS LRAELFYYAH SRCHTLSNCP RWNEGLRLLN SSTLNIVFRR 300
    QFMNEIVEWF EIFSQYTGSH YEFITECVHD KSAITAFKQE IEDYIKEGKQ 350
    ITLKSVVPEE HAAYRHILRL RESLMLAIDA ALSRIRSQSM GVL 393
    Length:393
    Mass (Da):46,438
    Last modified:December 1, 1992 - v1
    Checksum:iDB7FAD9AE2E3636F
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X60546 mRNA. Translation: CAA43036.1.
    PIRiA48357.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X60546 mRNA. Translation: CAA43036.1 .
    PIRi A48357.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Family and domain databases

    ProtoNeti Search...

    Publicationsi

    1. "Sequence analysis of three non structural proteins of a porcine group C (Cowden strain) rotavirus."
      Bremont M., Chabanne-Vautherot D., Cohen J.
      Arch. Virol. 130:85-92(1993) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].

    Entry informationi

    Entry nameiNSP1_ROTPC
    AccessioniPrimary (citable) accession number: Q00033
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: December 1, 1992
    Last sequence update: December 1, 1992
    Last modified: October 1, 2014
    This is version 42 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programViral Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3