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Q00033

- NSP1_ROTPC

UniProt

Q00033 - NSP1_ROTPC

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Protein

Non-structural protein 1

Gene
N/A
Organism
Rotavirus C (strain Pig/United States/Cowden/1980) (RV-C)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli

Functioni

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri39 – 6830Sequence AnalysisAdd
BLAST

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. RNA binding Source: UniProtKB-KW

GO - Biological processi

  1. suppression by virus of host IRF3 activity Source: UniProtKB-KW
  2. suppression by virus of host IRF7 activity Source: UniProtKB-KW
  3. suppression by virus of host NF-kappaB transcription factor activity Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Host-virus interaction, Inhibition of host innate immune response by virus, Inhibition of host IRF3 by virus, Inhibition of host IRF7 by virus, Inhibition of host NF-kappa-B by virus, Inhibition of host RLR pathway by virus, Viral immunoevasion

Keywords - Ligandi

Metal-binding, RNA-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Non-structural protein 1
Short name:
NSP1
Alternative name(s):
NCVP2
Non-structural RNA-binding protein 53
Short name:
NS53
OrganismiRotavirus C (strain Pig/United States/Cowden/1980) (RV-C)
Taxonomic identifieri10916 [NCBI]
Taxonomic lineageiVirusesdsRNA virusesReoviridaeSedoreovirinaeRotavirus
Virus hostiSus scrofa (Pig) [TaxID: 9823]
ProteomesiUP000008175: Genome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 393393Non-structural protein 1PRO_0000149560Add
BLAST

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni2 – 7776RNA-bindingBy similarityAdd
BLAST

Sequence similaritiesi

Belongs to the rotavirus C NSP1 family.Curated

Zinc finger

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri39 – 6830Sequence AnalysisAdd
BLAST

Keywords - Domaini

Zinc-finger

Sequencei

Sequence statusi: Complete.

Q00033-1 [UniParc]FASTAAdd to Basket

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        10         20         30         40         50
MANSYREMLY WFGKTIDRNL PYVNTNGWRK QKGRKDGICL NCLDECKLYS
60 70 80 90 100
CDHCGIKHKC GNCVLSECFL DVKNEFNKYR WLVFDEEPDQ AVLLQHWIMY
110 120 130 140 150
KDYFLQKFNY RLATQAKILN MNKNQKFQLN EGRKRALSVP ITSQFLKFRL
160 170 180 190 200
FGKIYIQFGT IMTNKIQPWL ELSTLKIGYL QLLNVERCSE LMATRGQFTT
210 220 230 240 250
NVAKTACITE IKCRRPIYDN DCIIEAYLDK NDRGWKFAAI LGRRKIPVTQ
260 270 280 290 300
KLAMEYFMKS LRAELFYYAH SRCHTLSNCP RWNEGLRLLN SSTLNIVFRR
310 320 330 340 350
QFMNEIVEWF EIFSQYTGSH YEFITECVHD KSAITAFKQE IEDYIKEGKQ
360 370 380 390
ITLKSVVPEE HAAYRHILRL RESLMLAIDA ALSRIRSQSM GVL
Length:393
Mass (Da):46,438
Last modified:December 1, 1992 - v1
Checksum:iDB7FAD9AE2E3636F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X60546 mRNA. Translation: CAA43036.1.
PIRiA48357.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X60546 mRNA. Translation: CAA43036.1 .
PIRi A48357.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Family and domain databases

ProtoNeti Search...

Publicationsi

  1. "Sequence analysis of three non structural proteins of a porcine group C (Cowden strain) rotavirus."
    Bremont M., Chabanne-Vautherot D., Cohen J.
    Arch. Virol. 130:85-92(1993) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].

Entry informationi

Entry nameiNSP1_ROTPC
AccessioniPrimary (citable) accession number: Q00033
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 1, 1992
Last sequence update: December 1, 1992
Last modified: October 1, 2014
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3