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P9WMY8

- GLGSY_MYCTO

UniProt

P9WMY8 - GLGSY_MYCTO

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Protein

Glycogen synthase

Gene

MT3116

Organism
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Glucosyltransferase that uses UDP-glucose as the sugar donor to elongate alpha-(1->4)-glucans. Is involved in the biosynthesis of both 6-O-methylglucosyl lipopolysaccharides (MGLP) and glycogen. May also use ADP-glucose as substrate (By similarity).By similarity

Catalytic activityi

UDP-alpha-D-glucose + ((1->4)-alpha-D-glucosyl)(n) = UDP + ((1->4)-alpha-D-glucosyl)(n+1).

Pathwayi

GO - Molecular functioni

  1. glycogen (starch) synthase activity Source: UniProtKB-EC

GO - Biological processi

  1. glycogen biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Keywords - Biological processi

Carbohydrate metabolism, Glycogen biosynthesis, Glycogen metabolism

Enzyme and pathway databases

UniPathwayiUPA00164.

Names & Taxonomyi

Protein namesi
Recommended name:
Glycogen synthase (EC:2.4.1.11)
Alternative name(s):
Alpha-1,4-glucosyltransferase MT3116
UDP-glucose--glycogen glucosyltransferase
Gene namesi
Ordered Locus Names:MT3116
OrganismiMycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
Taxonomic identifieri83331 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacteriumMycobacterium tuberculosis complex
ProteomesiUP000001020: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 414414Glycogen synthasePRO_0000427219Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliP9WMY8.
SMRiP9WMY8. Positions 1-390.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyltransferase group 1 family.Curated

Phylogenomic databases

KOiK16150.

Family and domain databases

InterProiIPR001296. Glyco_trans_1.
IPR028098. Glyco_trans_4_N.
[Graphical view]
PfamiPF13579. Glyco_trans_4_4. 1 hit.
PF00534. Glycos_transf_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P9WMY8-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MRILMVSWEY PPVVIGGLGR HVHHLSTALA AAGHDVVVLS RCPSGTDPST
60 70 80 90 100
HPSSDEVTEG VRVIAAAQDP HEFTFGNDMM AWTLAMGHAM IRAGLRLKKL
110 120 130 140 150
GTDRSWRPDV VHAHDWLVAH PAIALAQFYD VPMVSTIHAT EAGRHSGWVS
160 170 180 190 200
GALSRQVHAV ESWLVRESDS LITCSASMND EITELFGPGL AEITVIRNGI
210 220 230 240 250
DAARWPFAAR RPRTGPAELL YVGRLEYEKG VHDAIAALPR LRRTHPGTTL
260 270 280 290 300
TIAGEGTQQD WLIDQARKHR VLRATRFVGH LDHTELLALL HRADAAVLPS
310 320 330 340 350
HYEPFGLVAL EAAAAGTPLV TSNIGGLGEA VINGQTGVSC APRDVAGLAA
360 370 380 390 400
AVRSVLDDPA AAQRRARAAR QRLTSDFDWQ TVATATAQVY LAAKRGERQP
410
QPRLPIVEHA LPDR
Length:414
Mass (Da):44,805
Last modified:April 16, 2014 - v1
Checksum:i64ADC7A4EA17A0DE
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE000516 Genomic DNA. Translation: AAK47446.1.
PIRiC70859.
RefSeqiNP_337632.1. NC_002755.2.

Genome annotation databases

GeneIDi923208.
KEGGimtc:MT3116.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE000516 Genomic DNA. Translation: AAK47446.1 .
PIRi C70859.
RefSeqi NP_337632.1. NC_002755.2.

3D structure databases

ProteinModelPortali P9WMY8.
SMRi P9WMY8. Positions 1-390.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 923208.
KEGGi mtc:MT3116.

Phylogenomic databases

KOi K16150.

Enzyme and pathway databases

UniPathwayi UPA00164 .

Family and domain databases

InterProi IPR001296. Glyco_trans_1.
IPR028098. Glyco_trans_4_N.
[Graphical view ]
Pfami PF13579. Glyco_trans_4_4. 1 hit.
PF00534. Glycos_transf_1. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CDC 1551 / Oshkosh.

Entry informationi

Entry nameiGLGSY_MYCTO
AccessioniPrimary (citable) accession number: P9WMY8
Secondary accession number(s): L0TCY4, O53279, Q7D693
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 16, 2014
Last sequence update: April 16, 2014
Last modified: October 29, 2014
This is version 7 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3