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P9WMY8

- GLGSY_MYCTO

UniProt

P9WMY8 - GLGSY_MYCTO

Protein

Glycogen synthase

Gene

MT3116

Organism
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 6 (01 Oct 2014)
      Sequence version 1 (16 Apr 2014)
      Previous versions | rss
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    Functioni

    Glucosyltransferase that uses UDP-glucose as the sugar donor to elongate alpha-(1->4)-glucans. Is involved in the biosynthesis of both 6-O-methylglucosyl lipopolysaccharides (MGLP) and glycogen. May also use ADP-glucose as substrate By similarity.By similarity

    Catalytic activityi

    UDP-alpha-D-glucose + ((1->4)-alpha-D-glucosyl)(n) = UDP + ((1->4)-alpha-D-glucosyl)(n+1).

    Pathwayi

    GO - Molecular functioni

    1. glycogen (starch) synthase activity Source: UniProtKB-EC

    GO - Biological processi

    1. glycogen biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Glycosyltransferase, Transferase

    Keywords - Biological processi

    Carbohydrate metabolism, Glycogen biosynthesis, Glycogen metabolism

    Enzyme and pathway databases

    UniPathwayiUPA00164.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glycogen synthase (EC:2.4.1.11)
    Alternative name(s):
    Alpha-1,4-glucosyltransferase MT3116
    UDP-glucose--glycogen glucosyltransferase
    Gene namesi
    Ordered Locus Names:MT3116
    OrganismiMycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
    Taxonomic identifieri83331 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacteriumMycobacterium tuberculosis complex
    ProteomesiUP000001020: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 414414Glycogen synthasePRO_0000427219Add
    BLAST

    Structurei

    3D structure databases

    ProteinModelPortaliP9WMY8.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the glycosyltransferase group 1 family.Curated

    Phylogenomic databases

    KOiK16150.

    Family and domain databases

    InterProiIPR001296. Glyco_trans_1.
    IPR028098. Glyco_trans_4_N.
    [Graphical view]
    PfamiPF13579. Glyco_trans_4_4. 1 hit.
    PF00534. Glycos_transf_1. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P9WMY8-1 [UniParc]FASTAAdd to Basket

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    MRILMVSWEY PPVVIGGLGR HVHHLSTALA AAGHDVVVLS RCPSGTDPST    50
    HPSSDEVTEG VRVIAAAQDP HEFTFGNDMM AWTLAMGHAM IRAGLRLKKL 100
    GTDRSWRPDV VHAHDWLVAH PAIALAQFYD VPMVSTIHAT EAGRHSGWVS 150
    GALSRQVHAV ESWLVRESDS LITCSASMND EITELFGPGL AEITVIRNGI 200
    DAARWPFAAR RPRTGPAELL YVGRLEYEKG VHDAIAALPR LRRTHPGTTL 250
    TIAGEGTQQD WLIDQARKHR VLRATRFVGH LDHTELLALL HRADAAVLPS 300
    HYEPFGLVAL EAAAAGTPLV TSNIGGLGEA VINGQTGVSC APRDVAGLAA 350
    AVRSVLDDPA AAQRRARAAR QRLTSDFDWQ TVATATAQVY LAAKRGERQP 400
    QPRLPIVEHA LPDR 414
    Length:414
    Mass (Da):44,805
    Last modified:April 16, 2014 - v1
    Checksum:i64ADC7A4EA17A0DE
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE000516 Genomic DNA. Translation: AAK47446.1.
    PIRiC70859.
    RefSeqiNP_337632.1. NC_002755.2.

    Genome annotation databases

    GeneIDi923208.
    KEGGimtc:MT3116.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE000516 Genomic DNA. Translation: AAK47446.1 .
    PIRi C70859.
    RefSeqi NP_337632.1. NC_002755.2.

    3D structure databases

    ProteinModelPortali P9WMY8.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 923208.
    KEGGi mtc:MT3116.

    Phylogenomic databases

    KOi K16150.

    Enzyme and pathway databases

    UniPathwayi UPA00164 .

    Family and domain databases

    InterProi IPR001296. Glyco_trans_1.
    IPR028098. Glyco_trans_4_N.
    [Graphical view ]
    Pfami PF13579. Glyco_trans_4_4. 1 hit.
    PF00534. Glycos_transf_1. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: CDC 1551 / Oshkosh.

    Entry informationi

    Entry nameiGLGSY_MYCTO
    AccessioniPrimary (citable) accession number: P9WMY8
    Secondary accession number(s): L0TCY4, O53279, Q7D693
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 16, 2014
    Last sequence update: April 16, 2014
    Last modified: October 1, 2014
    This is version 6 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3