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Protein

Glycogen synthase

Gene

MT3116

Organism
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Glucosyltransferase that uses UDP-glucose as the sugar donor to elongate alpha-(1->4)-glucans. Is involved in the biosynthesis of both 6-O-methylglucosyl lipopolysaccharides (MGLP) and glycogen. May also use ADP-glucose as substrate (By similarity).By similarity

Catalytic activityi

UDP-alpha-D-glucose + ((1->4)-alpha-D-glucosyl)(n) = UDP + ((1->4)-alpha-D-glucosyl)(n+1).

Pathway:iglycogen biosynthesis

This protein is involved in the pathway glycogen biosynthesis, which is part of Glycan biosynthesis.
View all proteins of this organism that are known to be involved in the pathway glycogen biosynthesis and in Glycan biosynthesis.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Keywords - Biological processi

Carbohydrate metabolism, Glycogen biosynthesis, Glycogen metabolism

Enzyme and pathway databases

UniPathwayiUPA00164.

Names & Taxonomyi

Protein namesi
Recommended name:
Glycogen synthase (EC:2.4.1.11)
Alternative name(s):
Alpha-1,4-glucosyltransferase MT3116
UDP-glucose--glycogen glucosyltransferase
Gene namesi
Ordered Locus Names:MT3116
OrganismiMycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
Taxonomic identifieri83331 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacteriumMycobacterium tuberculosis complex
ProteomesiUP000001020 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 414414Glycogen synthasePRO_0000427219Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliP9WMY8.
SMRiP9WMY8. Positions 1-390.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyltransferase group 1 family.Curated

Phylogenomic databases

KOiK16150.

Family and domain databases

InterProiIPR001296. Glyco_trans_1.
IPR028098. Glyco_trans_4_N.
[Graphical view]
PfamiPF13579. Glyco_trans_4_4. 1 hit.
PF00534. Glycos_transf_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P9WMY8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRILMVSWEY PPVVIGGLGR HVHHLSTALA AAGHDVVVLS RCPSGTDPST
60 70 80 90 100
HPSSDEVTEG VRVIAAAQDP HEFTFGNDMM AWTLAMGHAM IRAGLRLKKL
110 120 130 140 150
GTDRSWRPDV VHAHDWLVAH PAIALAQFYD VPMVSTIHAT EAGRHSGWVS
160 170 180 190 200
GALSRQVHAV ESWLVRESDS LITCSASMND EITELFGPGL AEITVIRNGI
210 220 230 240 250
DAARWPFAAR RPRTGPAELL YVGRLEYEKG VHDAIAALPR LRRTHPGTTL
260 270 280 290 300
TIAGEGTQQD WLIDQARKHR VLRATRFVGH LDHTELLALL HRADAAVLPS
310 320 330 340 350
HYEPFGLVAL EAAAAGTPLV TSNIGGLGEA VINGQTGVSC APRDVAGLAA
360 370 380 390 400
AVRSVLDDPA AAQRRARAAR QRLTSDFDWQ TVATATAQVY LAAKRGERQP
410
QPRLPIVEHA LPDR
Length:414
Mass (Da):44,805
Last modified:April 16, 2014 - v1
Checksum:i64ADC7A4EA17A0DE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000516 Genomic DNA. Translation: AAK47446.1.
PIRiC70859.
RefSeqiWP_003415928.1. NZ_KK341227.1.

Genome annotation databases

EnsemblBacteriaiAAK47446; AAK47446; MT3116.
KEGGimtc:MT3116.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000516 Genomic DNA. Translation: AAK47446.1.
PIRiC70859.
RefSeqiWP_003415928.1. NZ_KK341227.1.

3D structure databases

ProteinModelPortaliP9WMY8.
SMRiP9WMY8. Positions 1-390.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAK47446; AAK47446; MT3116.
KEGGimtc:MT3116.

Phylogenomic databases

KOiK16150.

Enzyme and pathway databases

UniPathwayiUPA00164.

Family and domain databases

InterProiIPR001296. Glyco_trans_1.
IPR028098. Glyco_trans_4_N.
[Graphical view]
PfamiPF13579. Glyco_trans_4_4. 1 hit.
PF00534. Glycos_transf_1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CDC 1551 / Oshkosh.

Entry informationi

Entry nameiGLGSY_MYCTO
AccessioniPrimary (citable) accession number: P9WMY8
Secondary accession number(s): L0TCY4, O53279, Q7D693
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 16, 2014
Last sequence update: April 16, 2014
Last modified: July 22, 2015
This is version 13 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.