Skip Header

 
Contribute Send feedback
Read comments (0) or add your own

Reviewed, UniProtKB/Swiss-Prot P99507 (SUCB1_CANFA)

Last modified June 16, 2009. Version 56. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Succinyl-CoA ligase [ADP-forming] subunit beta, mitochondrial
    EC=6.2.1.5
Alternative name(s):
    ATP-specific succinyl-CoA synthetase subunit beta
    Succinyl-CoA synthetase beta-A chain
      Short name=SCS-betaA
Gene names
Name: SUCLA2
OrganismCanis familiaris (Dog)
Taxonomic identifier9615 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCarnivoraCaniformiaCanidaeCanis

Protein attributes

Sequence length20 AA.
Sequence statusFragment.
Sequence processingThe displayed sequence is not processed.
Protein existenceEvidence at protein level.

General annotation (Comments)

Catalytic activity

ATP + succinate + CoA = ADP + phosphate + succinyl-CoA.

Pathway

Carbohydrate metabolism; tricarboxylic acid cycle.

Subunit structure

Heterodimer of an alpha and a beta subunit By similarity.

Subcellular location

Mitochondrion By similarity.

Sequence similarities

Belongs to the succinate/malate CoA ligase beta subunit family.

Contains 1 ATP-grasp domain.

Ontologies

Keywords
   Biological processTricarboxylic acid cycle
   Cellular componentMitochondrion
   LigandATP-binding
Nucleotide-binding
   Molecular functionLigase
   Technical termDirect protein sequencing
Gene Ontology (GO)
   Biological processtricarboxylic acid cycle

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentmitochondrion

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

succinate-CoA ligase (ADP-forming) activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – ›20›20Succinyl-CoA ligase [ADP-forming] subunit beta, mitochondrial
PRO_0000102813

Regions

Domain8 – ›20›13ATP-grasp

Experimental info

Non-terminal residue201

Sequences

Sequence LengthMass (Da)Tools
P99507-1 [UniParc].

Last modified July 15, 1998. Version 1.
Checksum: BE8AEFD54DBDAC2E

FASTA202,248
        10         20 
LSLHEYMSME LLQEAGVSIP 

« Hide

References

[1]"HSC-2DPAGE and the two-dimensional gel electrophoresis database of dog heart proteins."
Dunn M.J., Corbett J.M., Wheeler C.H.
Electrophoresis 18:2795-2802(1997) [PubMed: 9504812] [Abstract]
Cited for: PROTEIN SEQUENCE.
Tissue: Heart.

Cross-references

3D structure databases

ModBaseSearch...

2-D gel databases

HSC-2DPAGEP99507.

Phylogenomic databases

HOVERGENP99507.

Enzyme and pathway databases

BRENDA6.2.1.5. 463.

Family and domain databases

InterProIPR017866. Succ-CoA_synthase_bsu_CS.
IPR005809. Succ_CoA_synthase_bsu.
[Graphical view]
PANTHERPTHR11815. CoA_lig_beta. 1 hit.
PROSITEPS50975. ATP_GRASP. Partial match.
PS01217. SUCCINYL_COA_LIG_3. Partial match.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSUCB1_CANFA
AccessionPrimary (citable) accession number: P99507
Entry history
Integrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: July 15, 1998
Last modified: June 16, 2009
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHPI (Human Proteome Initiative)

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents