Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Phosphopentomutase

Gene

deoB

Organism
Staphylococcus aureus (strain N315)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Phosphotransfer between the C1 and C5 carbon atoms of pentose.UniRule annotation

Catalytic activityi

Alpha-D-ribose 1-phosphate = D-ribose 5-phosphate.UniRule annotation
2-deoxy-alpha-D-ribose 1-phosphate = 2-deoxy-alpha-D-ribose 5-phosphate.UniRule annotation

Cofactori

Mn2+UniRule annotationNote: Binds 1 or 2 manganese ions.UniRule annotation

Pathwayi: 5-phospho-alpha-D-ribose 1-diphosphate biosynthesis

This protein is involved in step 1 of the subpathway that synthesizes 5-phospho-alpha-D-ribose 1-diphosphate from D-ribose 5-phosphate (route II).UniRule annotation
Proteins known to be involved in the 3 steps of the subpathway in this organism are:
  1. Phosphopentomutase (deoB)
  2. no protein annotated in this organism
  3. no protein annotated in this organism
This subpathway is part of the pathway 5-phospho-alpha-D-ribose 1-diphosphate biosynthesis, which is itself part of Metabolic intermediate biosynthesis.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes 5-phospho-alpha-D-ribose 1-diphosphate from D-ribose 5-phosphate (route II), the pathway 5-phospho-alpha-D-ribose 1-diphosphate biosynthesis and in Metabolic intermediate biosynthesis.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi14ManganeseUniRule annotation1
Metal bindingi291ManganeseUniRule annotation1
Metal bindingi327ManganeseUniRule annotation1
Metal bindingi328ManganeseUniRule annotation1
Metal bindingi339ManganeseUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase
LigandManganese, Metal-binding

Enzyme and pathway databases

UniPathwayiUPA00087; UER00173.

Names & Taxonomyi

Protein namesi
Recommended name:
PhosphopentomutaseUniRule annotation (EC:5.4.2.7UniRule annotation)
Alternative name(s):
PhosphodeoxyribomutaseUniRule annotation
Gene namesi
Name:deoBUniRule annotation
Synonyms:drm
Ordered Locus Names:SA0134
OrganismiStaphylococcus aureus (strain N315)
Taxonomic identifieri158879 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcaceaeStaphylococcus
Proteomesi
  • UP000000751 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001998411 – 392PhosphopentomutaseAdd BLAST392

2D gel databases

SWISS-2DPAGEiP99100.

Structurei

3D structure databases

ProteinModelPortaliP99100.
SMRiP99100.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the phosphopentomutase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000008159.
KOiK01839.
OMAiCHASGTE.

Family and domain databases

CDDicd16009. PPM. 1 hit.
Gene3Di3.30.70.1250. 1 hit.
3.40.720.10. 1 hit.
HAMAPiMF_00740. Phosphopentomut. 1 hit.
InterProiView protein in InterPro
IPR017849. Alkaline_Pase-like_a/b/a.
IPR017850. Alkaline_phosphatase_core.
IPR010045. DeoB.
IPR006124. Metalloenzyme.
IPR024052. Phosphopentomutase_DeoB_cap.
PANTHERiPTHR21110. PTHR21110. 1 hit.
PfamiView protein in Pfam
PF01676. Metalloenzyme. 1 hit.
PIRSFiPIRSF001491. Ppentomutase. 1 hit.
SUPFAMiSSF143856. SSF143856. 1 hit.
SSF53649. SSF53649. 2 hits.
TIGRFAMsiTIGR01696. deoB. 1 hit.

Sequencei

Sequence statusi: Complete.

P99100-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTRPFNRVHL IVMDSVGIGE APDAADFKDE GSHTLRHTLE GFDQTLPNLE
60 70 80 90 100
KLGLGNIDKL PVVNAVEQPE AYYTKLSEAS VGKDTMTGHW EIMGLNIMQP
110 120 130 140 150
FKVYPNGFPE ELIQQIEEMT GRKVVANKPA SGTQIIDEWG EHQMKTGDLI
160 170 180 190 200
VYTSADPVLQ IAAHEDIIPL EELYDICEKV RELTKDPKYL IGRIIARPYV
210 220 230 240 250
GEPGNFTRTS NRHDYALKPF GKTVLDHLKD GGYDVIAIGK INDIYDGEGV
260 270 280 290 300
TEAVRTKSNM DGMDQLMKIV KKDFTGISFL NLVDFDALYG HRRDKPGYAQ
310 320 330 340 350
AIKDFDDRLP ELFSNLKEDD LVIITADHGN DPTAPGTDHT REYIPVIMYS
360 370 380 390
PKFKGGHALE SDTTFSSIGA TIADNFNVTL PEFGKSYLKE LK
Length:392
Mass (Da):43,796
Last modified:October 11, 2004 - v1
Checksum:i6012D71CD9BDB549
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000018 Genomic DNA. Translation: BAB41354.1.
PIRiG89774.
RefSeqiWP_000197806.1. NC_002745.2.

Genome annotation databases

EnsemblBacteriaiBAB41354; BAB41354; BAB41354.
GeneIDi31212946.
KEGGisau:SA0134.

Similar proteinsi

Entry informationi

Entry nameiDEOB_STAAN
AccessioniPrimary (citable) accession number: P99100
Secondary accession number(s): Q99X76
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 11, 2004
Last sequence update: October 11, 2004
Last modified: August 30, 2017
This is version 87 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families