SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

P98167

- SSPO_BOVIN

UniProt

P98167 - SSPO_BOVIN

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
SCO-spondin
Gene
SSPO
Organism
Bos taurus (Bovine)
Status
Reviewed - Annotation score: 3 out of 5 - Experimental evidence at transcript leveli

Functioni

Involved in the modulation of neuronal aggregation. May be involved in developmental events during the formation of the central nervous system.

GO - Molecular functioni

  1. peptidase inhibitor activity Source: InterPro

GO - Biological processi

  1. cell adhesion Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Cell adhesion

Keywords - Ligandi

Calcium

Names & Taxonomyi

Protein namesi
Recommended name:
SCO-spondin
Gene namesi
Name:SSPO
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
ProteomesiUP000009136: Unplaced

Subcellular locationi

GO - Cellular componenti

  1. extracellular space Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1717 Reviewed prediction
Add
BLAST
Chaini18 – 51465129SCO-spondin
PRO_0000186461Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi? ↔ 5138 By similarity
Glycosylationi80 – 801N-linked (GlcNAc...) Reviewed prediction
Glycosylationi122 – 1221N-linked (GlcNAc...) Reviewed prediction
Glycosylationi153 – 1531N-linked (GlcNAc...) Reviewed prediction
Glycosylationi255 – 2551N-linked (GlcNAc...) Reviewed prediction
Glycosylationi814 – 8141N-linked (GlcNAc...) Reviewed prediction
Glycosylationi906 – 9061N-linked (GlcNAc...) Reviewed prediction
Glycosylationi1349 – 13491N-linked (GlcNAc...) Reviewed prediction
Disulfide bondi1373 ↔ 1386 By similarity
Disulfide bondi1380 ↔ 1399 By similarity
Disulfide bondi1393 ↔ 1408 By similarity
Disulfide bondi1413 ↔ 1425 By similarity
Disulfide bondi1420 ↔ 1438 By similarity
Disulfide bondi1432 ↔ 1447 By similarity
Disulfide bondi1449 ↔ 1461 By similarity
Disulfide bondi1456 ↔ 1474 By similarity
Disulfide bondi1468 ↔ 1483 By similarity
Disulfide bondi1489 ↔ 1501 By similarity
Disulfide bondi1496 ↔ 1514 By similarity
Disulfide bondi1508 ↔ 1525 By similarity
Disulfide bondi1562 ↔ 1574 By similarity
Disulfide bondi1569 ↔ 1587 By similarity
Disulfide bondi1581 ↔ 1596 By similarity
Disulfide bondi1600 ↔ 1613 By similarity
Disulfide bondi1607 ↔ 1626 By similarity
Disulfide bondi1620 ↔ 1637 By similarity
Glycosylationi1647 – 16471N-linked (GlcNAc...) Reviewed prediction
Disulfide bondi1653 ↔ 1663 By similarity
Disulfide bondi1658 ↔ 1676 By similarity
Disulfide bondi1670 ↔ 1691 By similarity
Disulfide bondi1703 ↔ 1739 By similarity
Disulfide bondi1707 ↔ 1744 By similarity
Disulfide bondi1718 ↔ 1729 By similarity
Glycosylationi1806 – 18061N-linked (GlcNAc...) Reviewed prediction
Disulfide bondi1825 ↔ 1840 By similarity
Disulfide bondi1834 ↔ 1845 By similarity
Disulfide bondi1847 ↔ 1859 By similarity
Disulfide bondi1865 ↔ 1884 By similarity
Disulfide bondi1867 ↔ 1887 By similarity
Disulfide bondi1889 ↔ 1897 By similarity
Disulfide bondi1907 ↔ 1946 By similarity
Disulfide bondi1918 ↔ 1922 By similarity
Disulfide bondi1956 ↔ 1961 By similarity
Glycosylationi2027 – 20271N-linked (GlcNAc...) Reviewed prediction
Disulfide bondi2062 ↔ 2220 By similarity
Glycosylationi2127 – 21271N-linked (GlcNAc...) Reviewed prediction
Disulfide bondi2226 ↔ 2238 By similarity
Disulfide bondi2233 ↔ 2251 By similarity
Disulfide bondi2245 ↔ 2260 By similarity
Disulfide bondi2383 ↔ 2395 By similarity
Disulfide bondi2390 ↔ 2408 By similarity
Disulfide bondi2402 ↔ 2417 By similarity
Disulfide bondi2443 ↔ 2455 By similarity
Disulfide bondi2450 ↔ 2468 By similarity
Disulfide bondi2462 ↔ 2477 By similarity
Disulfide bondi2480 ↔ 2516 By similarity
Disulfide bondi2491 ↔ 2495 By similarity
Disulfide bondi2526 ↔ 2531 By similarity
Disulfide bondi2546 ↔ 2583 By similarity
Disulfide bondi2550 ↔ 2588 By similarity
Disulfide bondi2561 ↔ 2573 By similarity
Glycosylationi2624 – 26241N-linked (GlcNAc...) Reviewed prediction
Glycosylationi2673 – 26731N-linked (GlcNAc...) Reviewed prediction
Disulfide bondi2695 ↔ 2733 By similarity
Disulfide bondi2706 ↔ 2710 By similarity
Disulfide bondi2743 ↔ 2747 By similarity
Disulfide bondi2763 ↔ 2801 By similarity
Disulfide bondi2767 ↔ 2806 By similarity
Disulfide bondi2783 ↔ 2791 By similarity
Disulfide bondi2821 ↔ 2856 By similarity
Disulfide bondi2825 ↔ 2861 By similarity
Disulfide bondi2836 ↔ 2846 By similarity
Glycosylationi2915 – 29151N-linked (GlcNAc...) Reviewed prediction
Glycosylationi2946 – 29461N-linked (GlcNAc...) Reviewed prediction
Disulfide bondi2965 ↔ 3003 By similarity
Disulfide bondi2976 ↔ 2980 By similarity
Disulfide bondi3013 ↔ 3018 By similarity
Glycosylationi3041 – 30411N-linked (GlcNAc...) Reviewed prediction
Glycosylationi3143 – 31431N-linked (GlcNAc...) Reviewed prediction
Glycosylationi3153 – 31531N-linked (GlcNAc...) Reviewed prediction
Disulfide bondi3175 ↔ 3224 By similarity
Disulfide bondi3179 ↔ 3229 By similarity
Disulfide bondi3190 ↔ 3214 By similarity
Disulfide bondi3244 ↔ 3281 By similarity
Disulfide bondi3248 ↔ 3286 By similarity
Disulfide bondi3259 ↔ 3271 By similarity
Glycosylationi3290 – 32901N-linked (GlcNAc...) Reviewed prediction
Disulfide bondi3400 ↔ 3443 By similarity
Disulfide bondi3404 ↔ 3449 By similarity
Disulfide bondi3415 ↔ 3427 By similarity
Disulfide bondi3464 ↔ 3499 By similarity
Disulfide bondi3467 ↔ 3506 By similarity
Disulfide bondi3477 ↔ 3489 By similarity
Glycosylationi3502 – 35021N-linked (GlcNAc...) Reviewed prediction
Glycosylationi3580 – 35801N-linked (GlcNAc...) Reviewed prediction
Glycosylationi3607 – 36071N-linked (GlcNAc...) Reviewed prediction
Disulfide bondi3638 ↔ 3668 By similarity
Disulfide bondi3642 ↔ 3673 By similarity
Disulfide bondi3653 ↔ 3658 By similarity
Glycosylationi3783 – 37831N-linked (GlcNAc...) Reviewed prediction
Disulfide bondi3814 ↔ 3852 By similarity
Disulfide bondi3818 ↔ 3857 By similarity
Disulfide bondi3830 ↔ 3842 By similarity
Glycosylationi3906 – 39061N-linked (GlcNAc...) Reviewed prediction
Glycosylationi3938 – 39381N-linked (GlcNAc...) Reviewed prediction
Disulfide bondi3939 ↔ 3975 By similarity
Disulfide bondi3950 ↔ 3954 By similarity
Disulfide bondi3988 ↔ 3993 By similarity
Disulfide bondi4008 ↔ 4045 By similarity
Disulfide bondi4012 ↔ 4050 By similarity
Disulfide bondi4023 ↔ 4035 By similarity
Glycosylationi4131 – 41311N-linked (GlcNAc...) Reviewed prediction
Disulfide bondi4152 ↔ 4188 By similarity
Disulfide bondi4163 ↔ 4167 By similarity
Disulfide bondi4198 ↔ 4203 By similarity
Disulfide bondi4257 ↔ 4294 By similarity
Disulfide bondi4261 ↔ 4299 By similarity
Disulfide bondi4272 ↔ 4284 By similarity
Glycosylationi4341 – 43411N-linked (GlcNAc...) Reviewed prediction
Disulfide bondi4361 ↔ 4398 By similarity
Disulfide bondi4372 ↔ 4374 By similarity
Disulfide bondi4408 ↔ 4413 By similarity
Glycosylationi4412 – 44121N-linked (GlcNAc...) Reviewed prediction
Disulfide bondi4611 ↔ 4645 By similarity
Disulfide bondi4622 ↔ 4626 By similarity
Disulfide bondi4655 ↔ 4660 By similarity
Glycosylationi4729 – 47291N-linked (GlcNAc...) Reviewed prediction
Glycosylationi4746 – 47461N-linked (GlcNAc...) Reviewed prediction
Glycosylationi4751 – 47511N-linked (GlcNAc...) Reviewed prediction
Glycosylationi4772 – 47721N-linked (GlcNAc...) Reviewed prediction
Disulfide bondi4773 ↔ 4808 By similarity
Disulfide bondi4777 ↔ 4813 By similarity
Disulfide bondi4788 ↔ 4797 By similarity
Glycosylationi4861 – 48611N-linked (GlcNAc...) Reviewed prediction
Glycosylationi4901 – 49011N-linked (GlcNAc...) Reviewed prediction
Glycosylationi4947 – 49471N-linked (GlcNAc...) Reviewed prediction
Glycosylationi4954 – 49541N-linked (GlcNAc...) Reviewed prediction
Disulfide bondi5052 ↔ 5100 By similarity
Glycosylationi5060 – 50601N-linked (GlcNAc...) Reviewed prediction
Disulfide bondi5066 ↔ 5117 By similarity
Disulfide bondi5076 ↔ 5133 By similarity
Disulfide bondi5080 ↔ 5135 By similarity

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

PRIDEiP98167.

Expressioni

Tissue specificityi

Subcommissural organ. Located at the boundary of the diencephalon and mesencephalon beneath the posterior commissure at the point where the axons cross the midline.1 Publication

Developmental stagei

Embryo.

Structurei

3D structure databases

ProteinModelPortaliP98167.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini18 – 9477EMI
Add
BLAST
Domaini186 – 392207VWFD 1
Add
BLAST
Domaini464 – 51956TIL 1
Add
BLAST
Domaini558 – 768211VWFD 2
Add
BLAST
Domaini822 – 87554TIL 2
Add
BLAST
Domaini1009 – 1215207VWFD 3
Add
BLAST
Domaini1271 – 132757TIL 3
Add
BLAST
Domaini1372 – 140938LDL-receptor class A 1
Add
BLAST
Domaini1412 – 144736LDL-receptor class A 2
Add
BLAST
Domaini1448 – 148437LDL-receptor class A 3
Add
BLAST
Domaini1488 – 152639LDL-receptor class A 4
Add
BLAST
Domaini1561 – 159737LDL-receptor class A 5
Add
BLAST
Domaini1599 – 163840LDL-receptor class A 6
Add
BLAST
Domaini1652 – 169039LDL-receptor class A 7
Add
BLAST
Domaini1691 – 174555TSP type-1 1
Add
BLAST
Domaini1747 – 180559TSP type-1 2
Add
BLAST
Domaini1821 – 186040EGF-like 1
Add
BLAST
Domaini1861 – 189838EGF-like 2
Add
BLAST
Domaini1906 – 196257TSP type-1 3
Add
BLAST
Domaini1962 – 202261VWFC 1
Add
BLAST
Domaini2062 – 2220159F5/8 type C
Add
BLAST
Domaini2225 – 226137LDL-receptor class A 8
Add
BLAST
Domaini2382 – 241837LDL-receptor class A 9
Add
BLAST
Domaini2442 – 247837LDL-receptor class A 10
Add
BLAST
Domaini2479 – 253254TSP type-1 4
Add
BLAST
Domaini2534 – 258956TSP type-1 5
Add
BLAST
Domaini2612 – 265443TIL 4
Add
BLAST
Domaini2694 – 274855TSP type-1 6
Add
BLAST
Domaini2751 – 280757TSP type-1 7
Add
BLAST
Domaini2809 – 286254TSP type-1 8
Add
BLAST
Domaini2964 – 301956TSP type-1 9
Add
BLAST
Domaini3020 – 307152TSP type-1 10
Add
BLAST
Domaini3163 – 323068TSP type-1 11
Add
BLAST
Domaini3232 – 328756TSP type-1 12
Add
BLAST
Domaini3291 – 334555TIL 5
Add
BLAST
Domaini3388 – 345063TSP type-1 13
Add
BLAST
Domaini3452 – 350756TSP type-1 14
Add
BLAST
Domaini3626 – 367449TSP type-1 15
Add
BLAST
Domaini3802 – 385857TSP type-1 16
Add
BLAST
Domaini3872 – 392453TSP type-1 17
Add
BLAST
Domaini3938 – 399457TSP type-1 18
Add
BLAST
Domaini3996 – 405156TSP type-1 19
Add
BLAST
Domaini4101 – 416868VWFC 2
Add
BLAST
Domaini4151 – 420454TSP type-1 20
Add
BLAST
Domaini4245 – 430056TSP type-1 21
Add
BLAST
Domaini4302 – 435857TSP type-1 22
Add
BLAST
Domaini4360 – 441455TSP type-1 23
Add
BLAST
Domaini4610 – 466152TSP type-1 24
Add
BLAST
Domaini4761 – 481454TSP type-1 25
Add
BLAST
Domaini4816 – 487055TIL 6
Add
BLAST
Domaini4983 – 504159VWFC 3
Add
BLAST
Domaini5052 – 513988CTCK
Add
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi523 – 5275Poly-Arg

Sequence similaritiesi

Belongs to the thrombospondin family.
Contains 2 EGF-like domains.
Contains 1 EMI domain.
Contains 1 F5/8 type C domain.
Contains 25 TSP type-1 domains.
Contains 3 VWFC domains.
Contains 3 VWFD domains.

Keywords - Domaini

EGF-like domain, Repeat, Signal

Phylogenomic databases

eggNOGiNOG12793.
HOGENOMiHOG000154433.
HOVERGENiHBG080794.

Family and domain databases

Gene3Di2.60.120.260. 1 hit.
4.10.400.10. 8 hits.
InterProiIPR000421. Coagulation_fac_5/8-C_type_dom.
IPR006207. Cys_knot_C.
IPR008979. Galactose-bd-like.
IPR001545. Gonadotropin_bsu.
IPR023415. LDLR_class-A_CS.
IPR002172. LDrepeatLR_classA_rpt.
IPR008037. Prot_inh_PMP.
IPR000884. Thrombospondin_1_rpt.
IPR002919. TIL_dom.
IPR014853. Unchr_dom_Cys-rich.
IPR006552. VWC_out.
IPR001007. VWF_C.
IPR001846. VWF_type-D.
[Graphical view]
PfamiPF08742. C8. 3 hits.
PF00754. F5_F8_type_C. 1 hit.
PF00057. Ldl_recept_a. 8 hits.
PF01826. TIL. 13 hits.
PF00090. TSP_1. 22 hits.
PF00093. VWC. 1 hit.
PF00094. VWD. 3 hits.
[Graphical view]
PRINTSiPR00261. LDLRECEPTOR.
SMARTiSM00832. C8. 3 hits.
SM00041. CT. 1 hit.
SM00231. FA58C. 1 hit.
SM00068. GHB. 1 hit.
SM00192. LDLa. 10 hits.
SM00209. TSP1. 25 hits.
SM00214. VWC. 3 hits.
SM00215. VWC_out. 1 hit.
SM00216. VWD. 3 hits.
[Graphical view]
SUPFAMiSSF49785. SSF49785. 1 hit.
SSF57283. SSF57283. 1 hit.
SSF57424. SSF57424. 9 hits.
SSF57567. SSF57567. 14 hits.
SSF82895. SSF82895. 24 hits.
PROSITEiPS01225. CTCK_2. 1 hit.
PS01285. FA58C_1. 1 hit.
PS01286. FA58C_2. 1 hit.
PS50022. FA58C_3. 1 hit.
PS01209. LDLRA_1. 7 hits.
PS50068. LDLRA_2. 9 hits.
PS50092. TSP1. 25 hits.
PS01208. VWFC_1. 1 hit.
PS50184. VWFC_2. 2 hits.
PS51233. VWFD. 3 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P98167-1 [UniParc]FASTAAdd to Basket

« Hide

MLLPALLFGA AWALANGRWC EQTETVLVEE EVTPHQEDLV PCASLQHYQR     50
RGWRLDLTWS GRAGLCAIYK PPETRPAAWN RTVRACCPGW GGTHCTLALA 100
EASPEGHCFA TWLCNLGAGS VNASAGSLEE CCAQPWGHSW RDGRSQTCHS 150
CSNHSRLGST PSPAILQPLA GAVAQLWSQR QRPSATCATW SGFHYRTFDG 200
RHFHFLGRCT YLLAGAADAT WAVHLQPMGH CPQPGHCQLA RVMMGPEEVL 250
IRGENVTVNG RLVPEGASQL LPGLSLQWQG DWLVLSGGLG VVVRLDRSSS 300
VSISVDQELQ GQTQGLCGVY NGQPEDDFLE PGRGLAALAA TFGNSWRLPD 350
SELGCLDAVE AAQGCEDPLR GTETGTEAGQ LRAEAQDVCH QLLEGPFREC 400
HTQVPPAEYH EACLFAYCAG APAGSGRAER LEAVCATLAS YAQDCAARRI 450
AVRWRKPGFC ERLCPGGQLY SDCASACPPS CSAVGEGSEW SCGEECVSGC 500
ECPPGLFWDG ALCVPAARCP CYRRRRRYEP GDTVRQLCNP CECRDGRWLC 550
AQAPCAAECA VGGDGHYVTF DGRSFSFRGR AGCRFILVQD FAKRQLLIVL 600
EHGDCDAGSC LHAISVSLGD TLVQLRDSGV VLVDGQDVAL PWSAAGGLSV 650
SRASSSFLLL RWPGARILWG VSDPAAYITL DPHHAHQVQG LCGTFTRNQQ 700
DDFLTPAGDV ETSITAFASK FQVAGGGTCS LEACTPLSPC STHTERQVFA 750
EVACAILHGP TFQECHGLVD REAFHLRCLA AVCGCTPGRD CLCPVLAAYA 800
RRCAQEGALP SWRNQTFCPV LCPGGQEYQE CAPACDRNCG EPEDCGELDN 850
CVAGCNCPLG LLWDPEGQCV PPNLCPCQLG AHRYAPGSAT MKDCNHCVCQ 900
ERGLWNCTAH HCAPPRTFCP RELVYVPGAC LLTCDSLDAD RTCPPGSPGG 950
CVCPPGTVLL EERCVPPELC PCRHGGQWYL PNAAIQEDCN LCVCQGQQWH 1000
CTGQRCDGRC RASGAPHYVT FDGLALTFPG ACEYLLVREA SGQFMVSAQN 1050
LPCGASGLTC TKALTVRLQG TVVHMLRGRA VMVNGVSVTP PKVYSGPGLS 1100
LHTAGLFLLL STRLGLTLLW DGGTRVPVQL SPQLRGRVAG LCGDFDGDAS 1150
NDLRSRQGVL EPTAELAAHS WRLGPLCPEP GDLPHPCAVN AHRAGWARAR 1200
CGVVLQPLFA RCHVEVPPQQ HYEQCVYDAC GCDSGGDCEC LCSAIATYAD 1250
ECARHGIHVR WRSQELCPLQ CERGQVYEAC GPTCPATCHD HRPEPGWPCR 1300
AVACVEGCFC PEGTLLHGGV CLEPAACPCE WGGSFFPPGT VLQKDCGNNC 1350
TCRESQWLCG DDGGRCVEPG PGCAEGETPC RESGHCVPHG WLCDNQDDCG 1400
DGSDEEGCAT RVCGEGQVSC CSGRCLPLVL LCDGQDDCGD GMDEQGCPCP 1450
QDSLTCADGH CLPPARLCDG HPDCPDGADE ESCLGQVDCA PGEVSCVDGT 1500
CLGAIQLCDG VWDCLDGGDE GPGHCPLPSL PTPPAGTLPG PSAVSWKLHL 1550
PPWPVSALRL PCGPLDFACG SGECAPRGWR CDGEEDCADG SDESGCDRPC 1600
APHHAPCARG SHCVAAEQLC DGVPHCPDGS DEDPGACERL QAPGGPNRTG 1650
LPCPEYSCPD GLCIGFQQVC DGQPDCELAG TAGPSPEEQG CGAWGPWSPW 1700
ELCSRTCGPG VQGWSRRCSP PSLPVLWHCP GPERQTRACF AAACPEDGVW 1750
TSWSRWSPCS EPCGGVTARH RECHPPQNGG RTCATLPGGP PSTRETRPCP 1800
QDGCPNVTCS GELVFHACVP CPLTCDDISG QATCPPDRPC GGPGCWCPAG 1850
QVLGAQGRCV WPRQCPCLVD GSRYWPGQRV KTDCQLCVCQ DGRPRRCQPS 1900
LDCAVNCGWS AWSPWAECLG PCGSRSVQWS FRSPNNPRPA GRGHQCRGLH 1950
RKARRCQTEP CEGCEQDGRV HRVGERWRAG PCRVCQCLHD GSARCSPYCP 2000
LGSCPQDWVL VEGVGESCCH CVPPGENQTV HPMATPVPAP TPSPQIGAPL 2050
ITYLLPPPGD PCYSPLGLAR LPEGSLPASS QQLEHPAWAA ILRPAPGAPG 2100
WSPVEHADTQ GHTPPPYLQL DLLQPRNLTG IIVQGAGSSD WLQVSSDGLH 2150
WHSYRDIQHG TQPAPQLFPK NWNGPSTVWM FARMVQARHV RVWPSDGHHQ 2200
AAPSSDANLD GPLRVELLGC EPAPLCLGVG HRCVSGECAP RGAPCDGVED 2250
CKDGSDEEGC VTPPAGAGRI ESTAWSSAPS SAQPGQLPPQ PSEGLAEAEA 2300
DHWHPGRGSP VPPTGKGPAS LGSEPHPSPG GSVQTVTPTS QPEAQALRPE 2350
MAAVTVLPPH PMVTPEVPAG RSTTPGPFPH VQCSPGQVPC EVLGCVELEQ 2400
LCDGREDCLD GSDERPCAWA AGTVPFTVPT TTLPGLPASR DLCSPSQLTC 2450
GSGECLPVER RCDLQLDCQD GSDENGCVDC GLAPWSGWSS CSRSCGLGLA 2500
FQRRELLRPP LPGGSCPPDR LRSQPCFVQA CPVAGAWAEW EAWGPCSVSC 2550
GGGHRSRRRS CMDPPPKNGG APCPGPPQER APCGLQPCAG GTDCGQGRVH 2600
VSAELCRKGL VPPCPPSCLD PEANRSCSGL CLEGCRCPPG LLLQDAGCLP 2650
LSECPCLVGE ELQQPGVPFL LDNCSRCVCE KGALLCEPGG CPVPCGWSAW 2700
SSWGPCDRSC GSGLRARFRS PSNPPAASGG APCEGQRQEL QACYSACGAE 2750
VPGWTPWAPW SACSQSCLVP GGGPALRSRS RLCPGPGDTS CIGEATEEEP 2800
CSPPVCLGLG VWGQWAAWSA CSAPCNGGVQ TRGRRCSASA PGDPGCQGPH 2850
SQTRDCNTQP CTAQCPGDMV FRSAEQCRWE GGPCPGLCLA RGPGVECTGV 2900
CTAGCACPTG LFLHNSSCLP PSQCPCQLRG QLYAPGAVAR LDSCSNCTCI 2950
SGEMVCASEP CPVACGWSPW TPWSLCSRSC NVGVRRRFRA GTAPPAAFGG 3000
AACQGPNMEA EFCSLRPCGG PAGEWGPWSP CSVPCGGGYR NRTRGSSGPS 3050
PVDFSTCGLQ PCAGPAPGVC PPGKRWLDCA QGPASCAELS APRGADQPCH 3100
PGCYCPSGML LLNNACVPTQ DCPCTHGGRL HPPGSAVLRP CENCSCVSGL 3150
ITNCTSWPCK EGQPTWSPWT PWSECSASCG PARRHKHRFC TRPPGGAPSS 3200
MAPPLLLSSV PPLCPGPEAE EEPCLLPECD RAGGWGPWGP WSSCSRSCGG 3250
GLRSRSRACD QPPPQGLGDY CEGPRAQGAA CQALPCPVTN CTAIEGAEYS 3300
ACGPPCPRSC DDLVHCVWHC QPGCYCPPGQ VLSADGTVHV QPGHCSCLDL 3350
LTGERHRPGA QLAKPDGCNY CTCSEGQLTC TDLPCPVPGA WCPWSEWTAC 3400
SQPCQGQTRT RSRACSCPAP QHGGAPCPGE AGEAGAQHQR ETCASTPECP 3450
VDGAWSPWGP WSPCEVCLGR SHRSRECSWP PTSEGGRPCP GGHRQSRPCQ 3500
GNSTQCTDCA GGQDLLPCGQ PCPRSCEDLS PGVECQPDSM GCQQPRCGCP 3550
PGQLSQDGLC VTPSQCRCQY QPGAMGIPEN QSRSAGSGLS SWESLEPGEV 3600
VTGPCDNCTC VAGILQCQEV PACSGLGLWG SWGPWEDCSV SCGGGEQLRF 3650
RRCPRPPCPG PARQSRTCRT QVCREAGCPA GRLYRECQPS EGCPFSCAHV 3700
TGQVGCFSAG CEEGCHCPEG TFLHRSACVQ ECPCVLTALW LQGLGAAGAD 3750
PGAHLSVLGE NGQPLGPGDE LGSGQSLRTG CHNCSCAHGK LSCSVEACSK 3800
AAGGFSPWGP WGPCSRSCGG LGTRTRSRQC VRPMPAPGGQ GCHGPHWDLE 3850
YCPSPECPGA AGSTAEPATG LPGGWGLWSP WSPCSGTCTD PAHPAWRSRS 3900
RLCLANCTGG AASQERPCNL PSCTELPLCP GPGCEAGNCS WTAWAPWEPC 3950
SRSCGVGQQR RLRAYHPPGP GGHWCPDVLT AYQERRFCNL RACPVPGGWS 4000
RWSPWSWCDR SCGGGRSLRS RSCSSPPPKN GGAPCVGERH HARLCNPTPC 4050
EEGCPAGMEV VSCANRCPRR CSDLQEGIVC QEDQACQQGC RCPEGSLEQD 4100
GGCVPLGHCE CTDAQGHSWA PGSQHQEACN NCTCRAGQLS CTAQPCPPPA 4150
HCAWSRWSAW SPCSRSCGPA GQQSRFRSST SGSWAPECRE EQSQSQPCPQ 4200
SPCPPLCLQG TRPRSLGDSW LQDGCQQCSC TPEGIICEDA ECAGLGAWTP 4250
WSPWSDCPVS CGGGNQVRTR VCVASAPPRG GSPCLGPDVQ SQRCGLWPCP 4300
ALPDTCSWGP WGPCSRSCGP GLASRSASCP CLLAEAEPAC NSTSPRLDTQ 4350
ACYAGPCLEE CVWSSWSSWT RCSCEVLVQQ RYRHQRPAPG GAGAGPPCTR 4400
LDGHFRPCLT GNCSEDSCAP PFEFQACGSP CTGLCATYLS PWLCQDLPPC 4450
QPGCYCPEGL LEQAGGCVPP EQCNCQHVSG EGAGVTLAPG DRLQLGCKEC 4500
ECQRGELQCT SQGCQGLLPL SGWSEWSPCG PCLPLGLLAP ASRAALEERW 4550
PQDTAGLSPT SAPTLASEQH RHRLCLDPET GRPWAGDPDL CTVPLSQQRL 4600
CPDPGACQDL CQWGPWGAWS PCQVPCSGGF RLRWREAGIP PGGGCRGPWA 4650
QTESCNMGPC PGESCEAQDT VPTPDCANQC PRSCVDLWDR VECLQGPCRP 4700
GCRCPPGQLV QDGHCVPVSS CRCGLPSPNA SWALAPAEVV RLDCRNCTCV 4750
NGSLACSSHE CPTLGPWSAW SNCSAPCGGG TTKRHRSCKE GPGVTPCQAQ 4800
DMEQQQDCNL QPCPECPPGQ VLSACAVSCP RLCSHLQPGT PCMQEPCQLG 4850
CDCPRGQLLH NGTCVPPAEC PCTQLSLPWG LTLTLEEQHR ELPPGTLLTQ 4900
NCTHCICQGG AFSCSLTDCQ ECPPGETWQQ VAPGELGPCE QTCREPNATE 4950
TQGNCSGRQA PGCVCQRGHF RSQEGPCVPV DLCECWHHGR PHPPGSEWQK 5000
ACESCRCVSG ESICTQHCPP LTCAQGETAV QEPGGCCPTC RQEAPEEQPV 5050
SCRHLTELRN LTKGACYLEQ VEVNYCSGHC PSSTNVLPEE PYLQSQCDCC 5100
SYRLDPENPV RILNLRCPGG RTELVVLPVI HSCQCSACQG GDFSER 5146
Length:5,146
Mass (Da):543,593
Last modified:July 11, 2006 - v2
Checksum:i724C5FB8727E13DA
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AJ416457 mRNA. Translation: CAC94914.1.
X93922 mRNA. Translation: CAA63815.1.
RefSeqiNP_777131.1. NM_174706.2.
UniGeneiBt.4812.

Genome annotation databases

GeneIDi282659.
KEGGibta:282659.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AJ416457 mRNA. Translation: CAC94914.1 .
X93922 mRNA. Translation: CAA63815.1 .
RefSeqi NP_777131.1. NM_174706.2.
UniGenei Bt.4812.

3D structure databases

ProteinModelPortali P98167.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi P98167.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 282659.
KEGGi bta:282659.

Organism-specific databases

CTDi 23145.

Phylogenomic databases

eggNOGi NOG12793.
HOGENOMi HOG000154433.
HOVERGENi HBG080794.

Miscellaneous databases

NextBioi 20806337.

Family and domain databases

Gene3Di 2.60.120.260. 1 hit.
4.10.400.10. 8 hits.
InterProi IPR000421. Coagulation_fac_5/8-C_type_dom.
IPR006207. Cys_knot_C.
IPR008979. Galactose-bd-like.
IPR001545. Gonadotropin_bsu.
IPR023415. LDLR_class-A_CS.
IPR002172. LDrepeatLR_classA_rpt.
IPR008037. Prot_inh_PMP.
IPR000884. Thrombospondin_1_rpt.
IPR002919. TIL_dom.
IPR014853. Unchr_dom_Cys-rich.
IPR006552. VWC_out.
IPR001007. VWF_C.
IPR001846. VWF_type-D.
[Graphical view ]
Pfami PF08742. C8. 3 hits.
PF00754. F5_F8_type_C. 1 hit.
PF00057. Ldl_recept_a. 8 hits.
PF01826. TIL. 13 hits.
PF00090. TSP_1. 22 hits.
PF00093. VWC. 1 hit.
PF00094. VWD. 3 hits.
[Graphical view ]
PRINTSi PR00261. LDLRECEPTOR.
SMARTi SM00832. C8. 3 hits.
SM00041. CT. 1 hit.
SM00231. FA58C. 1 hit.
SM00068. GHB. 1 hit.
SM00192. LDLa. 10 hits.
SM00209. TSP1. 25 hits.
SM00214. VWC. 3 hits.
SM00215. VWC_out. 1 hit.
SM00216. VWD. 3 hits.
[Graphical view ]
SUPFAMi SSF49785. SSF49785. 1 hit.
SSF57283. SSF57283. 1 hit.
SSF57424. SSF57424. 9 hits.
SSF57567. SSF57567. 14 hits.
SSF82895. SSF82895. 24 hits.
PROSITEi PS01225. CTCK_2. 1 hit.
PS01285. FA58C_1. 1 hit.
PS01286. FA58C_2. 1 hit.
PS50022. FA58C_3. 1 hit.
PS01209. LDLRA_1. 7 hits.
PS50068. LDLRA_2. 9 hits.
PS50092. TSP1. 25 hits.
PS01208. VWFC_1. 1 hit.
PS50184. VWFC_2. 2 hits.
PS51233. VWFD. 3 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Subcommissural organ/Reissner's fiber complex: characterization of SCO-spondin, a glycoprotein with potent activity on neurite outgrowth."
    Gobron S.
    Glia 32:177-191(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA], TISSUE SPECIFICITY.
    Tissue: Subcommissural organ.
  2. "SCO-spondin: a new member of the thrombospondin family secreted by the subcommissural organ is a candidate in the modulation of neuronal aggregation."
    Gobron S., Monnerie H., Meiniel R., Creveaux I., Lehmann W., Lamalle D., Dastugue B., Meiniel A.
    J. Cell Sci. 109:1053-1061(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1719-2585.
    Tissue: Ependymocyte.

Entry informationi

Entry nameiSSPO_BOVIN
AccessioniPrimary (citable) accession number: P98167
Secondary accession number(s): Q8SPM4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: July 11, 2006
Last modified: June 11, 2014
This is version 108 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi