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Protein

Submaxillary mucin-like protein

Gene
N/A
Organism
Bos taurus (Bovine)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Submaxillary mucin-like protein
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
ProteomesiUP000009136: Unplaced

Subcellular locationi

GO - Cellular componenti

  1. extracellular region Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 563563Submaxillary mucin-like proteinPRO_0000158960Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi? ↔ 554PROSITE-ProRule annotation
Glycosylationi28 – 281N-linked (GlcNAc...)Sequence Analysis
Glycosylationi394 – 3941N-linked (GlcNAc...)Sequence Analysis
Disulfide bondi471 ↔ 518PROSITE-ProRule annotation
Glycosylationi477 – 4771N-linked (GlcNAc...)Sequence Analysis
Disulfide bondi485 ↔ 532PROSITE-ProRule annotation
Disulfide bondi494 ↔ 548PROSITE-ProRule annotation
Disulfide bondi498 ↔ 550PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

PRIDEiP98091.

Expressioni

Tissue specificityi

Submaxillary mucosae.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Repeati61 – 71111Add
BLAST
Repeati112 – 122112Add
BLAST
Repeati148 – 158113Add
BLAST
Domaini338 – 40467VWFCPROSITE-ProRule annotationAdd
BLAST
Domaini471 – 55585CTCKPROSITE-ProRule annotationAdd
BLAST

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni61 – 158983 X 11 AA repeatsAdd
BLAST

Sequence similaritiesi

Contains 1 CTCK (C-terminal cystine knot-like) domain.PROSITE-ProRule annotation
Contains 1 VWFC domain.PROSITE-ProRule annotation

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiNOG12793.
HOGENOMiHOG000203842.
HOVERGENiHBG006422.

Family and domain databases

InterProiIPR006207. Cys_knot_C.
IPR006208. Glyco_hormone_CN.
IPR001007. VWF_C.
[Graphical view]
PfamiPF00007. Cys_knot. 1 hit.
[Graphical view]
SMARTiSM00041. CT. 1 hit.
SM00214. VWC. 1 hit.
[Graphical view]
PROSITEiPS01185. CTCK_1. 1 hit.
PS01225. CTCK_2. 1 hit.
PS01208. VWFC_1. 1 hit.
PS50184. VWFC_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P98091-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKVLQENSPR HAISGSSHTE ATTLIVSNST SGTGLRPEDN TAVAGGQATG
60 70 80 90 100
RVTGTTKVIP GTTVAPGSSN TESTTSLGES RTRIGRITGA TTGTSKRSSP
110 120 130 140 150
GSKTGNTGAI SGTTVAPGSS NTGATTSLGS GETTQGGIKI VTMGVTTGTT
160 170 180 190 200
IAPGSSNTKA TTPTEVRTTT EVRTATETTT SRHSSDATGS GIQTGITGTG
210 220 230 240 250
SGTTSSPGGF NAEATTFKEH VRTTETRILS GTTRGRSGTT VIPESSNTGT
260 270 280 290 300
STGVGRQTST AVVSGRVTGV SESSSPGTSK EASETTTGPG ISTTGSTSKS
310 320 330 340 350
NRITTSSRIP YPETTVVATG EQETETKTGC TTSLPPPPAC YGPLGEKKSP
360 370 380 390 400
GDIWTANCHK CTCTDAETVD CKLKECPSPP TCKPEERLVK FKDNDTCCEI
410 420 430 440 450
AYCEPRTCLF NNNDYEVGAS FADPKNPCIS YSCHNTGFVA VVQDCPKQTW
460 470 480 490 500
CAEEDRVYDS TKCCYTCKPY CRSSSVNVTV NYNGCKKKVE MARCAGECKK
510 520 530 540 550
TIKYDYDIFQ LKNSCLCCQE ENYEYREIDL DCPDGGTIPY RYRHIITCSC
560
LDICQQSMTS TVS
Length:563
Mass (Da):58,913
Last modified:February 1, 1996 - v1
Checksum:iAB326CD78E5FFFCF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M36192 mRNA. Translation: AAA30657.1.
PIRiA36054.
UniGeneiBt.141.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M36192 mRNA. Translation: AAA30657.1.
PIRiA36054.
UniGeneiBt.141.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiP98091.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiNOG12793.
HOGENOMiHOG000203842.
HOVERGENiHBG006422.

Family and domain databases

InterProiIPR006207. Cys_knot_C.
IPR006208. Glyco_hormone_CN.
IPR001007. VWF_C.
[Graphical view]
PfamiPF00007. Cys_knot. 1 hit.
[Graphical view]
SMARTiSM00041. CT. 1 hit.
SM00214. VWC. 1 hit.
[Graphical view]
PROSITEiPS01185. CTCK_1. 1 hit.
PS01225. CTCK_2. 1 hit.
PS01208. VWFC_1. 1 hit.
PS50184. VWFC_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Cloning and cDNA sequence of a bovine submaxillary gland mucin-like protein containing two distinct domains."
    Bhargava A.K., Woitach J.T., Davidson E.A., Bhavanandan V.P.
    Proc. Natl. Acad. Sci. U.S.A. 87:6798-6802(1990) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Tissue: Submandibular gland.

Entry informationi

Entry nameiMUCS_BOVIN
AccessioniPrimary (citable) accession number: P98091
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: February 1, 1996
Last modified: January 7, 2015
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.