Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

P98057

- COX14_BRADU

UniProt

P98057 - COX14_BRADU

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Probable cytochrome c oxidase subunit 1

Gene

blr2715

Organism
Bradyrhizobium diazoefficiens (strain JCM 10833 / IAM 13628 / NBRC 14792 / USDA 110)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi105 – 1051Iron (low-spin heme axial ligand)By similarity
Metal bindingi283 – 2831Copper BBy similarity
Metal bindingi287 – 2871Copper BBy similarity
Metal bindingi332 – 3321Copper BBy similarity
Metal bindingi333 – 3331Copper BBy similarity
Metal bindingi418 – 4181Iron (high-spin heme axial ligand)By similarity
Metal bindingi420 – 4201Iron (low-spin heme axial ligand)By similarity

GO - Molecular functioni

  1. cytochrome-c oxidase activity Source: UniProtKB-EC
  2. heme binding Source: InterPro
  3. iron ion binding Source: InterPro
  4. oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor Source: InterPro

GO - Biological processi

  1. aerobic respiration Source: InterPro
  2. oxidative phosphorylation Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Biological processi

Electron transport, Respiratory chain, Transport

Keywords - Ligandi

Copper, Heme, Iron, Metal-binding

Enzyme and pathway databases

BioCyciBJAP224911:GJEJ-2739-MONOMER.
UniPathwayiUPA00705.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable cytochrome c oxidase subunit 1 (EC:1.9.3.1)
Alternative name(s):
Cytochrome c oxidase polypeptide I
Fourth terminal oxidase
Gene namesi
Ordered Locus Names:blr2715
OrganismiBradyrhizobium diazoefficiens (strain JCM 10833 / IAM 13628 / NBRC 14792 / USDA 110)
Taxonomic identifieri224911 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBradyrhizobiaceaeBradyrhizobium
ProteomesiUP000002526: Chromosome

Subcellular locationi

Cell membrane By similarity; Multi-pass membrane protein By similarity

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: UniProtKB-KW
  3. respiratory chain Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 666666Probable cytochrome c oxidase subunit 1PRO_0000183471Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Cross-linki283 ↔ 2871'-histidyl-3'-tyrosine (His-Tyr)By similarity

Interactioni

Protein-protein interaction databases

STRINGi224911.blr2715.

Structurei

3D structure databases

ProteinModelPortaliP98057.
SMRiP98057. Positions 52-551.
ModBaseiSearch...
MobiDBiSearch...

Transmembrane

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei16 – 3621HelicalSequence AnalysisAdd
BLAST
Transmembranei57 – 7721HelicalSequence AnalysisAdd
BLAST
Transmembranei108 – 12821HelicalSequence AnalysisAdd
BLAST
Transmembranei142 – 16221HelicalSequence AnalysisAdd
BLAST
Transmembranei192 – 21221HelicalSequence AnalysisAdd
BLAST
Transmembranei234 – 25421HelicalSequence AnalysisAdd
BLAST
Transmembranei277 – 29721HelicalSequence AnalysisAdd
BLAST
Transmembranei315 – 33521HelicalSequence AnalysisAdd
BLAST
Transmembranei346 – 36621HelicalSequence AnalysisAdd
BLAST
Transmembranei380 – 40021HelicalSequence AnalysisAdd
BLAST
Transmembranei413 – 43321HelicalSequence AnalysisAdd
BLAST
Transmembranei456 – 47621HelicalSequence AnalysisAdd
BLAST
Transmembranei493 – 51321HelicalSequence AnalysisAdd
BLAST
Transmembranei591 – 61121HelicalSequence AnalysisAdd
BLAST
Transmembranei612 – 63221HelicalSequence AnalysisAdd
BLAST

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG0843.
HOGENOMiHOG000085275.
InParanoidiP98057.
KOiK02298.
OrthoDBiEOG6B35XR.
PhylomeDBiP98057.

Family and domain databases

Gene3Di1.20.210.10. 1 hit.
InterProiIPR000883. COX1.
IPR023615. Cyt_c_Oxase_su1_BS.
IPR023616. Cyt_c_Oxase_su1_dom.
IPR014207. Cyt_c_ubiqinol_oxidase_su1.
[Graphical view]
PANTHERiPTHR10422. PTHR10422. 1 hit.
PfamiPF00115. COX1. 1 hit.
[Graphical view]
PRINTSiPR01165. CYCOXIDASEI.
SUPFAMiSSF81442. SSF81442. 1 hit.
TIGRFAMsiTIGR02843. CyoB. 1 hit.
PROSITEiPS50855. COX1. 1 hit.
PS00077. COX1_CUB. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P98057-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MLGKLDWSAI PFDQPIPLIA GAVVLVAILA VLVWVVVKGH LPYLWHEWIT
60 70 80 90 100
SVDHKRIGVM YILLASIMLL RGGSDAIMMR IQQAVAYQSQ GYLPPEHYNQ
110 120 130 140 150
IFSAHGTIMI FFVAMPFVIG LMNLVVPLQL GVRDVAFPTL NSVGFWLTAT
160 170 180 190 200
GALLVNLSLV IGEFARTGWL AFPPLSGLSY SPGVGVDYYA WSLQISGVGT
210 220 230 240 250
LVAGINLVTT VLKLRTKGMN YLRMPMFCWT TLASNLLIVA AFPILTATLA
260 270 280 290 300
MLLLDRYLGF HFFTNEAGGN VMMFMNLIWA WGHPEVYILV LPAFGIFSEV
310 320 330 340 350
VSTFSGKALF GYRSMVLATM AICVISFMVW LHHFFTMGAG PDVNAIFGIA
360 370 380 390 400
SMIIAVPTGV KIYNWLFTMY GGRIRFATPM LWAVGFMVTF IIGGLTGVLV
410 420 430 440 450
AVPPADFMLH NSMFLVAHFH NVIIGGVLFG AFAGFEYWFP KAFGFRLDER
460 470 480 490 500
WGKLAFWFTF LGFYVTFMPL YIAGMLGMTR RLQHYDVAAW RPWMLVAAAG
510 520 530 540 550
MAVLTIGVIC QIMQLVVSIR NREALRDRTG DPWDGRSLEW ATSSPPPVFN
560 570 580 590 600
FAFSPDVRGE DAYWDMKTHA RQQSFEHDAP EYHDIEMPRN SPTGFICAFF
610 620 630 640 650
ATIMGFALIW HIWWMVILGG IGAFATFVVF AWRDHDEYVI PADEVARIDR
660
INLEERRSLV SMAGVV
Length:666
Mass (Da):74,469
Last modified:February 28, 2003 - v2
Checksum:iF04F4870CD039861
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti204 – 2041G → D in AAA26210. (PubMed:8200541)Curated

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L25841 Genomic DNA. Translation: AAA26210.1.
BA000040 Genomic DNA. Translation: BAC47980.1.
RefSeqiNP_769355.1. NC_004463.1.

Genome annotation databases

EnsemblBacteriaiBAC47980; BAC47980; BAC47980.
GeneIDi1054159.
KEGGibja:blr2715.
PATRICi21188868. VBIBraJap65052_2692.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L25841 Genomic DNA. Translation: AAA26210.1 .
BA000040 Genomic DNA. Translation: BAC47980.1 .
RefSeqi NP_769355.1. NC_004463.1.

3D structure databases

ProteinModelPortali P98057.
SMRi P98057. Positions 52-551.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 224911.blr2715.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAC47980 ; BAC47980 ; BAC47980 .
GeneIDi 1054159.
KEGGi bja:blr2715.
PATRICi 21188868. VBIBraJap65052_2692.

Phylogenomic databases

eggNOGi COG0843.
HOGENOMi HOG000085275.
InParanoidi P98057.
KOi K02298.
OrthoDBi EOG6B35XR.
PhylomeDBi P98057.

Enzyme and pathway databases

UniPathwayi UPA00705 .
BioCyci BJAP224911:GJEJ-2739-MONOMER.

Family and domain databases

Gene3Di 1.20.210.10. 1 hit.
InterProi IPR000883. COX1.
IPR023615. Cyt_c_Oxase_su1_BS.
IPR023616. Cyt_c_Oxase_su1_dom.
IPR014207. Cyt_c_ubiqinol_oxidase_su1.
[Graphical view ]
PANTHERi PTHR10422. PTHR10422. 1 hit.
Pfami PF00115. COX1. 1 hit.
[Graphical view ]
PRINTSi PR01165. CYCOXIDASEI.
SUPFAMi SSF81442. SSF81442. 1 hit.
TIGRFAMsi TIGR02843. CyoB. 1 hit.
PROSITEi PS50855. COX1. 1 hit.
PS00077. COX1_CUB. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Genetic evidence for a fourth terminal oxidase in Bradyrhizobium japonicum."
    Surpin M.A., Moshiri F., Murphy A.M., Maier R.J.
    Gene 143:73-77(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: JCM 10833 / IAM 13628 / NBRC 14792 / USDA 110.

Entry informationi

Entry nameiCOX14_BRADU
AccessioniPrimary (citable) accession number: P98057
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: February 28, 2003
Last modified: October 29, 2014
This is version 101 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3