Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

P98056

- FIXN_AZOC5

UniProt

P98056 - FIXN_AZOC5

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Cytochrome c oxidase subunit 1 homolog

Gene

fixN

Organism
Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / ORS 571)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. Co I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c or a quinol are transferred to the bimetallic center formed by a high-spin heme and copper B.

Catalytic activityi

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi132 – 1321Iron (low-spin heme axial ligand)By similarity
Metal bindingi281 – 2811Copper BBy similarity
Metal bindingi331 – 3311Copper BBy similarity
Metal bindingi332 – 3321Copper BBy similarity
Metal bindingi419 – 4191Iron (high-spin heme axial ligand)By similarity
Metal bindingi421 – 4211Iron (low-spin heme axial ligand)By similarity

GO - Molecular functioni

  1. cytochrome-c oxidase activity Source: UniProtKB-EC
  2. heme binding Source: InterPro
  3. iron ion binding Source: InterPro

GO - Biological processi

  1. aerobic respiration Source: InterPro
  2. oxidative phosphorylation Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Biological processi

Electron transport, Respiratory chain, Transport

Keywords - Ligandi

Copper, Heme, Iron, Metal-binding

Enzyme and pathway databases

BioCyciACAU438753:GJF3-4588-MONOMER.
UniPathwayiUPA00705.

Names & Taxonomyi

Protein namesi
Recommended name:
Cytochrome c oxidase subunit 1 homolog (EC:1.9.3.1)
Alternative name(s):
Cytochrome c oxidase polypeptide I homolog
Gene namesi
Name:fixN
Ordered Locus Names:AZC_4523
OrganismiAzorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / ORS 571)
Taxonomic identifieri438753 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesXanthobacteraceaeAzorhizobium
ProteomesiUP000000270: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane respiratory chain complex IV Source: InterPro
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 551551Cytochrome c oxidase subunit 1 homologPRO_0000183468Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi438753.AZC_4523.

Structurei

3D structure databases

ProteinModelPortaliP98056.
ModBaseiSearch...
MobiDBiSearch...

Transmembrane

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei14 – 3421HelicalSequence AnalysisAdd
BLAST
Transmembranei40 – 6021HelicalSequence AnalysisAdd
BLAST
Transmembranei88 – 10821HelicalSequence AnalysisAdd
BLAST
Transmembranei133 – 15321HelicalSequence AnalysisAdd
BLAST
Transmembranei169 – 18921HelicalSequence AnalysisAdd
BLAST
Transmembranei202 – 22221HelicalSequence AnalysisAdd
BLAST
Transmembranei229 – 24921HelicalSequence AnalysisAdd
BLAST
Transmembranei280 – 30021HelicalSequence AnalysisAdd
BLAST
Transmembranei313 – 33321HelicalSequence AnalysisAdd
BLAST
Transmembranei345 – 36521HelicalSequence AnalysisAdd
BLAST
Transmembranei383 – 40321HelicalSequence AnalysisAdd
BLAST
Transmembranei424 – 44421HelicalSequence AnalysisAdd
BLAST
Transmembranei459 – 47921HelicalSequence AnalysisAdd
BLAST
Transmembranei513 – 53321HelicalSequence AnalysisAdd
BLAST

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG3278.
HOGENOMiHOG000277908.
KOiK00404.
OMAiRLIEWHF.
OrthoDBiEOG6G7QZX.

Family and domain databases

Gene3Di1.20.210.10. 1 hit.
InterProiIPR000883. COX1.
IPR023615. Cyt_c_Oxase_su1_BS.
IPR023616. Cyt_c_Oxase_su1_dom.
IPR004677. Cyt_c_oxidase_cbb3_su1.
[Graphical view]
PANTHERiPTHR10422. PTHR10422. 1 hit.
PfamiPF00115. COX1. 1 hit.
[Graphical view]
SUPFAMiSSF81442. SSF81442. 1 hit.
TIGRFAMsiTIGR00780. ccoN. 1 hit.
PROSITEiPS50855. COX1. 1 hit.
PS00077. COX1_CUB. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P98056-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSIVQTPAKR MTGGELGLIL VFAALGFFSI VVAAKAYTPE YAFHAYLFAA
60 70 80 90 100
ASIATVFVIG NRYMDRPAEL PPQTIDGKPN YNMAPVKVGT LLAVFWGIAG
110 120 130 140 150
FLIGVIIALQ MAYPLFNFDL PWISFGRLRP LHTSAVIFAF GGNVLIATSF
160 170 180 190 200
YVVQRTSHAR LAGYLAPWFV VLGYNFFIVI AGTGYLLGIT QGKEYAEPEW
210 220 230 240 250
YADLWLTIVW VTYFLVFLGT VLKRKEPHIY VANWFYLAFI LTIAVLHLGN
260 270 280 290 300
NAAIPVSVFS PKSYIVWSGV QDAMVQWWYG HNAVGFFLTA GFLALMYYFI
310 320 330 340 350
PKRADKPVYS YRLSIVHFWA LIFLYIWAGP HHLHYTALPD WAQTLGMTFS
360 370 380 390 400
IMLWMPSWGG MINGLMTLSG AWDKLRTDPI IRMMVVAVAF YGMATFEGPM
410 420 430 440 450
MSVKSVNSLS HYTEWGIGHV HSGALGWVAY ISFGAIYCLI PWLWNKREMY
460 470 480 490 500
SMKAIEWHFW VSTLGIVLYI CAMWVAGILQ GLMWRAYTAL GFLEYSFIET
510 520 530 540 550
VEAMHPLYVI RAIGGILFLA GSLIMAWNVF MTITRAETVS QPSGAALAPA

E
Length:551
Mass (Da):61,843
Last modified:February 1, 1996 - v1
Checksum:i0466F71CD04BFC4D
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X74410 Genomic DNA. Translation: CAA52429.1.
AP009384 Genomic DNA. Translation: BAF90521.1.
PIRiA55582.
RefSeqiWP_012173042.1. NC_009937.1.
YP_001527439.1. NC_009937.1.

Genome annotation databases

EnsemblBacteriaiBAF90521; BAF90521; AZC_4523.
GeneIDi5692366.
KEGGiazc:AZC_4523.
PATRICi21025989. VBIAzoCau17976_4717.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X74410 Genomic DNA. Translation: CAA52429.1 .
AP009384 Genomic DNA. Translation: BAF90521.1 .
PIRi A55582.
RefSeqi WP_012173042.1. NC_009937.1.
YP_001527439.1. NC_009937.1.

3D structure databases

ProteinModelPortali P98056.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 438753.AZC_4523.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAF90521 ; BAF90521 ; AZC_4523 .
GeneIDi 5692366.
KEGGi azc:AZC_4523.
PATRICi 21025989. VBIAzoCau17976_4717.

Phylogenomic databases

eggNOGi COG3278.
HOGENOMi HOG000277908.
KOi K00404.
OMAi RLIEWHF.
OrthoDBi EOG6G7QZX.

Enzyme and pathway databases

UniPathwayi UPA00705 .
BioCyci ACAU438753:GJF3-4588-MONOMER.

Family and domain databases

Gene3Di 1.20.210.10. 1 hit.
InterProi IPR000883. COX1.
IPR023615. Cyt_c_Oxase_su1_BS.
IPR023616. Cyt_c_Oxase_su1_dom.
IPR004677. Cyt_c_oxidase_cbb3_su1.
[Graphical view ]
PANTHERi PTHR10422. PTHR10422. 1 hit.
Pfami PF00115. COX1. 1 hit.
[Graphical view ]
SUPFAMi SSF81442. SSF81442. 1 hit.
TIGRFAMsi TIGR00780. ccoN. 1 hit.
PROSITEi PS50855. COX1. 1 hit.
PS00077. COX1_CUB. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Role of the fixGHI region of Azorhizobium caulinodans in free-living and symbiotic nitrogen fixation."
    Mandon K., Kaminski P.A., Mougel C., Desnoues N., Elmerich C.
    FEMS Microbiol. Lett. 114:185-189(1993) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  2. "Functional analysis of the fixNOQP region of Azorhizobium caulinodans."
    Mandon K., Kaminski P.A., Elmerich C.
    J. Bacteriol. 176:2560-2568(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  3. "Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571."
    Lee K.B., Backer P.D., Aono T., Liu C.T., Suzuki S., Suzuki T., Kaneko T., Yamada M., Tabata S., Kupfer D.M., Najar F.Z., Wiley G.B., Roe B., Binnewies T., Ussery D., Vereecke D., Gevers D., Holsters M., Oyaizu H.
    Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 43989 / DSM 5975 / ORS 571.

Entry informationi

Entry nameiFIXN_AZOC5
AccessioniPrimary (citable) accession number: P98056
Secondary accession number(s): A8HZ09
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: February 1, 1996
Last modified: October 1, 2014
This is version 99 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3