Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

P98056

- FIXN_AZOC5

UniProt

P98056 - FIXN_AZOC5

Protein

Cytochrome c oxidase subunit 1 homolog

Gene

fixN

Organism
Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / ORS 571)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 99 (01 Oct 2014)
      Sequence version 1 (01 Feb 1996)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. Co I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c or a quinol are transferred to the bimetallic center formed by a high-spin heme and copper B.

    Catalytic activityi

    4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi132 – 1321Iron (low-spin heme axial ligand)By similarity
    Metal bindingi281 – 2811Copper BBy similarity
    Metal bindingi331 – 3311Copper BBy similarity
    Metal bindingi332 – 3321Copper BBy similarity
    Metal bindingi419 – 4191Iron (high-spin heme axial ligand)By similarity
    Metal bindingi421 – 4211Iron (low-spin heme axial ligand)By similarity

    GO - Molecular functioni

    1. cytochrome-c oxidase activity Source: UniProtKB-EC
    2. heme binding Source: InterPro
    3. iron ion binding Source: InterPro

    GO - Biological processi

    1. aerobic respiration Source: InterPro
    2. oxidative phosphorylation Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Oxidoreductase

    Keywords - Biological processi

    Electron transport, Respiratory chain, Transport

    Keywords - Ligandi

    Copper, Heme, Iron, Metal-binding

    Enzyme and pathway databases

    BioCyciACAU438753:GJF3-4588-MONOMER.
    UniPathwayiUPA00705.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Cytochrome c oxidase subunit 1 homolog (EC:1.9.3.1)
    Alternative name(s):
    Cytochrome c oxidase polypeptide I homolog
    Gene namesi
    Name:fixN
    Ordered Locus Names:AZC_4523
    OrganismiAzorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / ORS 571)
    Taxonomic identifieri438753 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesXanthobacteraceaeAzorhizobium
    ProteomesiUP000000270: Chromosome

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. plasma membrane respiratory chain complex IV Source: InterPro

    Keywords - Cellular componenti

    Cell membrane, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 551551Cytochrome c oxidase subunit 1 homologPRO_0000183468Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi438753.AZC_4523.

    Structurei

    3D structure databases

    ProteinModelPortaliP98056.
    ModBaseiSearch...
    MobiDBiSearch...

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei14 – 3421HelicalSequence AnalysisAdd
    BLAST
    Transmembranei40 – 6021HelicalSequence AnalysisAdd
    BLAST
    Transmembranei88 – 10821HelicalSequence AnalysisAdd
    BLAST
    Transmembranei133 – 15321HelicalSequence AnalysisAdd
    BLAST
    Transmembranei169 – 18921HelicalSequence AnalysisAdd
    BLAST
    Transmembranei202 – 22221HelicalSequence AnalysisAdd
    BLAST
    Transmembranei229 – 24921HelicalSequence AnalysisAdd
    BLAST
    Transmembranei280 – 30021HelicalSequence AnalysisAdd
    BLAST
    Transmembranei313 – 33321HelicalSequence AnalysisAdd
    BLAST
    Transmembranei345 – 36521HelicalSequence AnalysisAdd
    BLAST
    Transmembranei383 – 40321HelicalSequence AnalysisAdd
    BLAST
    Transmembranei424 – 44421HelicalSequence AnalysisAdd
    BLAST
    Transmembranei459 – 47921HelicalSequence AnalysisAdd
    BLAST
    Transmembranei513 – 53321HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiCOG3278.
    HOGENOMiHOG000277908.
    KOiK00404.
    OMAiRLIEWHF.
    OrthoDBiEOG6G7QZX.

    Family and domain databases

    Gene3Di1.20.210.10. 1 hit.
    InterProiIPR000883. COX1.
    IPR023615. Cyt_c_Oxase_su1_BS.
    IPR023616. Cyt_c_Oxase_su1_dom.
    IPR004677. Cyt_c_oxidase_cbb3_su1.
    [Graphical view]
    PANTHERiPTHR10422. PTHR10422. 1 hit.
    PfamiPF00115. COX1. 1 hit.
    [Graphical view]
    SUPFAMiSSF81442. SSF81442. 1 hit.
    TIGRFAMsiTIGR00780. ccoN. 1 hit.
    PROSITEiPS50855. COX1. 1 hit.
    PS00077. COX1_CUB. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P98056-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSIVQTPAKR MTGGELGLIL VFAALGFFSI VVAAKAYTPE YAFHAYLFAA    50
    ASIATVFVIG NRYMDRPAEL PPQTIDGKPN YNMAPVKVGT LLAVFWGIAG 100
    FLIGVIIALQ MAYPLFNFDL PWISFGRLRP LHTSAVIFAF GGNVLIATSF 150
    YVVQRTSHAR LAGYLAPWFV VLGYNFFIVI AGTGYLLGIT QGKEYAEPEW 200
    YADLWLTIVW VTYFLVFLGT VLKRKEPHIY VANWFYLAFI LTIAVLHLGN 250
    NAAIPVSVFS PKSYIVWSGV QDAMVQWWYG HNAVGFFLTA GFLALMYYFI 300
    PKRADKPVYS YRLSIVHFWA LIFLYIWAGP HHLHYTALPD WAQTLGMTFS 350
    IMLWMPSWGG MINGLMTLSG AWDKLRTDPI IRMMVVAVAF YGMATFEGPM 400
    MSVKSVNSLS HYTEWGIGHV HSGALGWVAY ISFGAIYCLI PWLWNKREMY 450
    SMKAIEWHFW VSTLGIVLYI CAMWVAGILQ GLMWRAYTAL GFLEYSFIET 500
    VEAMHPLYVI RAIGGILFLA GSLIMAWNVF MTITRAETVS QPSGAALAPA 550
    E 551
    Length:551
    Mass (Da):61,843
    Last modified:February 1, 1996 - v1
    Checksum:i0466F71CD04BFC4D
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X74410 Genomic DNA. Translation: CAA52429.1.
    AP009384 Genomic DNA. Translation: BAF90521.1.
    PIRiA55582.
    RefSeqiWP_012173042.1. NC_009937.1.
    YP_001527439.1. NC_009937.1.

    Genome annotation databases

    EnsemblBacteriaiBAF90521; BAF90521; AZC_4523.
    GeneIDi5692366.
    KEGGiazc:AZC_4523.
    PATRICi21025989. VBIAzoCau17976_4717.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X74410 Genomic DNA. Translation: CAA52429.1 .
    AP009384 Genomic DNA. Translation: BAF90521.1 .
    PIRi A55582.
    RefSeqi WP_012173042.1. NC_009937.1.
    YP_001527439.1. NC_009937.1.

    3D structure databases

    ProteinModelPortali P98056.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 438753.AZC_4523.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai BAF90521 ; BAF90521 ; AZC_4523 .
    GeneIDi 5692366.
    KEGGi azc:AZC_4523.
    PATRICi 21025989. VBIAzoCau17976_4717.

    Phylogenomic databases

    eggNOGi COG3278.
    HOGENOMi HOG000277908.
    KOi K00404.
    OMAi RLIEWHF.
    OrthoDBi EOG6G7QZX.

    Enzyme and pathway databases

    UniPathwayi UPA00705 .
    BioCyci ACAU438753:GJF3-4588-MONOMER.

    Family and domain databases

    Gene3Di 1.20.210.10. 1 hit.
    InterProi IPR000883. COX1.
    IPR023615. Cyt_c_Oxase_su1_BS.
    IPR023616. Cyt_c_Oxase_su1_dom.
    IPR004677. Cyt_c_oxidase_cbb3_su1.
    [Graphical view ]
    PANTHERi PTHR10422. PTHR10422. 1 hit.
    Pfami PF00115. COX1. 1 hit.
    [Graphical view ]
    SUPFAMi SSF81442. SSF81442. 1 hit.
    TIGRFAMsi TIGR00780. ccoN. 1 hit.
    PROSITEi PS50855. COX1. 1 hit.
    PS00077. COX1_CUB. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Role of the fixGHI region of Azorhizobium caulinodans in free-living and symbiotic nitrogen fixation."
      Mandon K., Kaminski P.A., Mougel C., Desnoues N., Elmerich C.
      FEMS Microbiol. Lett. 114:185-189(1993) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    2. "Functional analysis of the fixNOQP region of Azorhizobium caulinodans."
      Mandon K., Kaminski P.A., Elmerich C.
      J. Bacteriol. 176:2560-2568(1994) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    3. "Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571."
      Lee K.B., Backer P.D., Aono T., Liu C.T., Suzuki S., Suzuki T., Kaneko T., Yamada M., Tabata S., Kupfer D.M., Najar F.Z., Wiley G.B., Roe B., Binnewies T., Ussery D., Vereecke D., Gevers D., Holsters M., Oyaizu H.
      Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 43989 / DSM 5975 / ORS 571.

    Entry informationi

    Entry nameiFIXN_AZOC5
    AccessioniPrimary (citable) accession number: P98056
    Secondary accession number(s): A8HZ09
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 1, 1996
    Last sequence update: February 1, 1996
    Last modified: October 1, 2014
    This is version 99 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3