Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

P98055

- FIXN_AGRT7

UniProt

P98055 - FIXN_AGRT7

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Cytochrome c oxidase subunit 1 homolog

Gene

fixN

Organism
Agrobacterium tumefaciens (strain T37)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. Co I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c or a quinol are transferred to the bimetallic center formed by a high-spin heme and copper B.

Catalytic activityi

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi117 – 1171Iron (low-spin heme axial ligand)By similarity
Metal bindingi266 – 2661Copper BBy similarity
Metal bindingi316 – 3161Copper BBy similarity
Metal bindingi317 – 3171Copper BBy similarity
Metal bindingi404 – 4041Iron (high-spin heme axial ligand)By similarity
Metal bindingi406 – 4061Iron (low-spin heme axial ligand)By similarity

GO - Molecular functioni

  1. cytochrome-c oxidase activity Source: UniProtKB-EC
  2. heme binding Source: InterPro
  3. iron ion binding Source: InterPro

GO - Biological processi

  1. aerobic respiration Source: InterPro
  2. oxidative phosphorylation Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Biological processi

Electron transport, Respiratory chain, Transport

Keywords - Ligandi

Copper, Heme, Iron, Metal-binding

Enzyme and pathway databases

BioCyciRETL1328306-WGS:GSTH-4453-MONOMER.
RETL1328306-WGS:GSTH-5784-MONOMER.
UniPathwayiUPA00705.

Names & Taxonomyi

Protein namesi
Recommended name:
Cytochrome c oxidase subunit 1 homolog (EC:1.9.3.1)
Alternative name(s):
Cytochrome c oxidase polypeptide I homolog
Gene namesi
Name:fixN
OrganismiAgrobacterium tumefaciens (strain T37)
Taxonomic identifieri176300 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeRhizobium/Agrobacterium groupAgrobacteriumAgrobacterium tumefaciens complex

Subcellular locationi

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane respiratory chain complex IV Source: InterPro
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 539539Cytochrome c oxidase subunit 1 homologPRO_0000183467Add
BLAST

Structurei

Transmembrane

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei28 – 4821HelicalSequence AnalysisAdd
BLAST
Transmembranei75 – 9521HelicalSequence AnalysisAdd
BLAST
Transmembranei118 – 13821HelicalSequence AnalysisAdd
BLAST
Transmembranei154 – 17421HelicalSequence AnalysisAdd
BLAST
Transmembranei187 – 20721HelicalSequence AnalysisAdd
BLAST
Transmembranei214 – 23421HelicalSequence AnalysisAdd
BLAST
Transmembranei265 – 28521HelicalSequence AnalysisAdd
BLAST
Transmembranei298 – 31821HelicalSequence AnalysisAdd
BLAST
Transmembranei330 – 35021HelicalSequence AnalysisAdd
BLAST
Transmembranei368 – 38821HelicalSequence AnalysisAdd
BLAST
Transmembranei402 – 42221HelicalSequence AnalysisAdd
BLAST
Transmembranei443 – 46321HelicalSequence AnalysisAdd
BLAST
Transmembranei498 – 51821HelicalSequence AnalysisAdd
BLAST

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Family and domain databases

Gene3Di1.20.210.10. 1 hit.
InterProiIPR000883. COX1.
IPR023615. Cyt_c_Oxase_su1_BS.
IPR023616. Cyt_c_Oxase_su1_dom.
IPR004677. Cyt_c_oxidase_cbb3_su1.
[Graphical view]
PANTHERiPTHR10422. PTHR10422. 1 hit.
PfamiPF00115. COX1. 1 hit.
[Graphical view]
SUPFAMiSSF81442. SSF81442. 1 hit.
TIGRFAMsiTIGR00780. ccoN. 1 hit.
PROSITEiPS50855. COX1. 1 hit.
PS00077. COX1_CUB. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P98055-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MNYTLETADR ALGAFPALLG AAFAHDSLFA AHMWVLFFTL VVSTLLLLRR
60 70 80 90 100
VSFLPPVAGP PCRRTEYFDE VVKYGVMATV FWGVVGFLVG VVVALQLAFP
110 120 130 140 150
DLNIAPYFNF GRMRPLHTSA VIFAFGGNAL IATSFYVVQR TCRARLFGGN
160 170 180 190 200
LGWFVFWGYN LFIIMAATGY LLGITQGREY AEPEWYVDLW LTIVWVAYLA
210 220 230 240 250
TFLGTILTRK EPHISVANWF YLSFIVTIAM LHIVNNLAVP VSFLGVKSYS
260 270 280 290 300
AFSGVQAALT QWWYGHNAVG FFLTAGFLGM MYYFIPKQVN RPVYSYRLSI
310 320 330 340 350
IHFWALIFMY IWAGPHHLHY TALPDWAQTL GMVFSIMLWM PSWGGMINGL
360 370 380 390 400
MTLSGAWDKI RTDPIVRMMV MAVAFYGMAT FEGPMMSIKA VNSLSHYTDW
410 420 430 440 450
TIGHVHSGAL GWNGMITFGA IYYLTPKLWG RDRLYSLQLV NWHFWLATLG
460 470 480 490 500
IVVYAAVMWV AGIQQALMWR EYDSQGFLVY SFAESVAALF PYYVMRALGG
510 520 530
LMFLSGALIM AYNVTMTILG HQREEGASKG AAPSLQPAE
Length:539
Mass (Da):60,651
Last modified:February 1, 1996 - v1
Checksum:i6D99827DCA2E0C5F
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Z46239 Genomic DNA. Translation: CAA86308.1.
PIRiS54758. S49495.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Z46239 Genomic DNA. Translation: CAA86308.1 .
PIRi S54758. S49495.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Enzyme and pathway databases

UniPathwayi UPA00705 .
BioCyci RETL1328306-WGS:GSTH-4453-MONOMER.
RETL1328306-WGS:GSTH-5784-MONOMER.

Family and domain databases

Gene3Di 1.20.210.10. 1 hit.
InterProi IPR000883. COX1.
IPR023615. Cyt_c_Oxase_su1_BS.
IPR023616. Cyt_c_Oxase_su1_dom.
IPR004677. Cyt_c_oxidase_cbb3_su1.
[Graphical view ]
PANTHERi PTHR10422. PTHR10422. 1 hit.
Pfami PF00115. COX1. 1 hit.
[Graphical view ]
SUPFAMi SSF81442. SSF81442. 1 hit.
TIGRFAMsi TIGR00780. ccoN. 1 hit.
PROSITEi PS50855. COX1. 1 hit.
PS00077. COX1_CUB. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "A homolog of the Rhizobium meliloti nitrogen fixation gene fixN is involved in the production of a microaerobically induced oxidase activity in the phytopathogenic bacterium Agrobacterium tumefaciens."
    Schlueter A., Rueberg S., Kraemer M., Weidner S., Priefer U.
    Mol. Gen. Genet. 247:206-215(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Entry informationi

Entry nameiFIXN_AGRT7
AccessioniPrimary (citable) accession number: P98055
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: February 1, 1996
Last modified: October 1, 2014
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3