SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

P98053

- COXM_BRADU

UniProt

P98053 - COXM_BRADU

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Alternative cytochrome c oxidase subunit 2
Gene
coxM, bll3785
Organism
Bradyrhizobium diazoefficiens (strain JCM 10833 / IAM 13628 / NBRC 14792 / USDA 110)
Status
Reviewed - Annotation score: 3 out of 5 - Experimental evidence at transcript leveli

Functioni

Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1.

Catalytic activityi

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi190 – 1901Copper A Inferred
Metal bindingi225 – 2251Copper A Inferred
Metal bindingi229 – 2291Copper A Inferred
Metal bindingi233 – 2331Copper A Inferred

GO - Molecular functioni

  1. copper ion binding Source: InterPro
  2. cytochrome-c oxidase activity Source: UniProtKB-EC

GO - Biological processi

  1. electron transport chain Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Biological processi

Electron transport, Transport

Keywords - Ligandi

Copper, Heme, Iron, Metal-binding

Enzyme and pathway databases

BioCyciBJAP224911:GJEJ-3809-MONOMER.
RETL1328306-WGS:GSTH-2650-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Alternative cytochrome c oxidase subunit 2 (EC:1.9.3.1)
Alternative name(s):
Alternative cytochrome c oxidase polypeptide II
Cytochrome BB3 subunit 2
Oxidase BB(3) subunit 2
Gene namesi
Name:coxM
Ordered Locus Names:bll3785
OrganismiBradyrhizobium diazoefficiens (strain JCM 10833 / IAM 13628 / NBRC 14792 / USDA 110)
Taxonomic identifieri224911 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBradyrhizobiaceaeBradyrhizobium
ProteomesiUP000002526: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 4040Periplasmic Reviewed prediction
Add
BLAST
Transmembranei41 – 6121Helical; Reviewed prediction
Add
BLAST
Topological domaini62 – 8322Cytoplasmic Reviewed prediction
Add
BLAST
Transmembranei84 – 10421Helical; Reviewed prediction
Add
BLAST
Topological domaini105 – 277173Periplasmic Reviewed prediction
Add
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 277277Alternative cytochrome c oxidase subunit 2
PRO_0000183724Add
BLAST

Expressioni

Developmental stagei

Bacteroid (nitrogen-fixing endosymbiont).

Interactioni

Protein-protein interaction databases

STRINGi224911.bll3785.

Structurei

3D structure databases

ProteinModelPortaliP98053.

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG1622.
HOGENOMiHOG000268576.
KOiK02275.
OrthoDBiEOG68SVXT.
PhylomeDBiP98053.

Family and domain databases

Gene3Di1.10.287.90. 1 hit.
2.60.40.420. 1 hit.
InterProiIPR001505. Copper_CuA.
IPR008972. Cupredoxin.
IPR002429. Cyt_c_oxidase_su2_C.
IPR011759. Cyt_c_oxidase_su2_TM_dom.
[Graphical view]
PfamiPF00116. COX2. 1 hit.
[Graphical view]
SUPFAMiSSF49503. SSF49503. 1 hit.
SSF81464. SSF81464. 1 hit.
PROSITEiPS00078. COX2. 1 hit.
PS50857. COX2_CUA. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P98053-1 [UniParc]FASTAAdd to Basket

« Hide

MAVALILLLI AIGSVLFHLF SPWWWTPIAT NWGYIDDTIN ITFWITGFVF    50
TAVILFMAYC VFRFHHKEGR QAAYNPENKK LEWWLSVGTG VGVAAMLAPG 100
LVVWHQFVTV PADATEVEIM GQQWQWSFRL PGKDGRLGTS DVRNISPENP 150
MGLNRDDPHG QDDVVIENGD LHLPIGKPVK VLLRSVDVLH DFYVPEFRAK 200
MDMVPGMVTY FWIRPIRTGT FDVLCAELCG AAHYQMRAKV IVEAESDYHA 250
WLEQQKTFAG LSGRNAVVRA KYNSGDD 277
Length:277
Mass (Da):31,327
Last modified:October 1, 1996 - v1
Checksum:iD262ADE2233D36E1
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X68547 Genomic DNA. Translation: CAA48547.1.
BA000040 Genomic DNA. Translation: BAC49050.1.
PIRiB48364.
RefSeqiNP_770425.1. NC_004463.1.

Genome annotation databases

EnsemblBacteriaiBAC49050; BAC49050; BAC49050.
GeneIDi1053041.
KEGGibja:bll3785.
PATRICi21191037. VBIBraJap65052_3776.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X68547 Genomic DNA. Translation: CAA48547.1 .
BA000040 Genomic DNA. Translation: BAC49050.1 .
PIRi B48364.
RefSeqi NP_770425.1. NC_004463.1.

3D structure databases

ProteinModelPortali P98053.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 224911.bll3785.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAC49050 ; BAC49050 ; BAC49050 .
GeneIDi 1053041.
KEGGi bja:bll3785.
PATRICi 21191037. VBIBraJap65052_3776.

Phylogenomic databases

eggNOGi COG1622.
HOGENOMi HOG000268576.
KOi K02275.
OrthoDBi EOG68SVXT.
PhylomeDBi P98053.

Enzyme and pathway databases

BioCyci BJAP224911:GJEJ-3809-MONOMER.
RETL1328306-WGS:GSTH-2650-MONOMER.

Family and domain databases

Gene3Di 1.10.287.90. 1 hit.
2.60.40.420. 1 hit.
InterProi IPR001505. Copper_CuA.
IPR008972. Cupredoxin.
IPR002429. Cyt_c_oxidase_su2_C.
IPR011759. Cyt_c_oxidase_su2_TM_dom.
[Graphical view ]
Pfami PF00116. COX2. 1 hit.
[Graphical view ]
SUPFAMi SSF49503. SSF49503. 1 hit.
SSF81464. SSF81464. 1 hit.
PROSITEi PS00078. COX2. 1 hit.
PS50857. COX2_CUA. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Genes for a second terminal oxidase in Bradyrhizobium japonicum."
    Bott M., Preisig O., Hennecke H.
    Arch. Microbiol. 158:335-343(1992) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: USDA 110spc4.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: JCM 10833 / IAM 13628 / NBRC 14792 / USDA 110.

Entry informationi

Entry nameiCOXM_BRADU
AccessioniPrimary (citable) accession number: P98053
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: July 9, 2014
This is version 99 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi