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Protein

Solute carrier family 35 member B1

Gene

Slc35b1

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Probable sugar transporter.By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processSugar transport, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Solute carrier family 35 member B1
Alternative name(s):
UDP-galactose translocator 2
UDP-galactose transporter-related protein 1
Short name:
UGTrel1
Gene namesi
Name:Slc35b1
Synonyms:Ugalt2
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 11

Organism-specific databases

MGIiMGI:1343133 Slc35b1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei12 – 32HelicalSequence analysisAdd BLAST21
Transmembranei51 – 71HelicalSequence analysisAdd BLAST21
Transmembranei85 – 105HelicalSequence analysisAdd BLAST21
Transmembranei136 – 156HelicalSequence analysisAdd BLAST21
Transmembranei168 – 188HelicalSequence analysisAdd BLAST21
Transmembranei210 – 230HelicalSequence analysisAdd BLAST21
Transmembranei243 – 263HelicalSequence analysisAdd BLAST21
Transmembranei285 – 305HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Endoplasmic reticulum, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002133671 – 322Solute carrier family 35 member B1Add BLAST322

Proteomic databases

MaxQBiP97858
PaxDbiP97858
PeptideAtlasiP97858
PRIDEiP97858

Expressioni

Gene expression databases

BgeeiENSMUSG00000020873
CleanExiMM_SLC35B1
ExpressionAtlasiP97858 baseline and differential
GenevisibleiP97858 MM

Interactioni

Protein-protein interaction databases

BioGridi225355, 1 interactor
STRINGi10090.ENSMUSP00000021243

Structurei

3D structure databases

ProteinModelPortaliP97858
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi318 – 322Di-lysine motif5

Domaini

The di-lysine motif confers endoplasmic reticulum localization for type I membrane proteins.By similarity

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG1580 Eukaryota
COG0697 LUCA
GeneTreeiENSGT00530000063090
HOGENOMiHOG000091197
HOVERGENiHBG083706
InParanoidiP97858
KOiK15275
OMAiTRKMFTM
OrthoDBiEOG091G0LP3
PhylomeDBiP97858
TreeFamiTF105967

Family and domain databases

InterProiView protein in InterPro
IPR013657 UAA
PfamiView protein in Pfam
PF08449 UAA, 1 hit

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform 1 (identifier: P97858-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MAASRSLVPD RLRLPLCFLG VFVCYFYYGI LQEKITRGKY GEGPKQETFT
60 70 80 90 100
FALTLVFIQC VINAMFAKIL IQFFDTARVD RTRTWLYAAC SVSYVGAMVS
110 120 130 140 150
SNSALQFVNY PTQVLGKSCK PIPVMLLGVT LLKKKYPLAK YLCVLLIVAG
160 170 180 190 200
VALFMYKPKK VVGIEEHTVG FGELLLLMSL TLDGLTGVSQ DHMRAHYQTG
210 220 230 240 250
SNHMMLNINL WSTFLLGAGI LFTGELWEFL SFAERYPTII YNILLFGLTS
260 270 280 290 300
ALGQSFIFMT VVYFGPLTCS IITTTRKFFT ILASVILFAN PISSMQWVGT
310 320
VLVFLGLGLD AKFGKGTKKT SH
Length:322
Mass (Da):35,883
Last modified:May 1, 1997 - v1
Checksum:i3251E99195AAA4A4
GO
Isoform 2 (identifier: P97858-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-97: Missing.

Note: No experimental confirmation available.
Show »
Length:225
Mass (Da):24,820
Checksum:iD42FB49677F84BC6
GO

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_0161921 – 97Missing in isoform 2. 1 PublicationAdd BLAST97

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D87990 mRNA Translation: BAA13526.1
AK002961 mRNA Translation: BAC25013.1
AL662875 Genomic DNA Translation: CAI25968.1
BC002029 mRNA Translation: AAH02029.1
CCDSiCCDS25277.1 [P97858-1]
PIRiJC5025
RefSeqiNP_058032.1, NM_016752.1
XP_006532048.1, XM_006531985.1 [P97858-2]
UniGeneiMm.4593

Genome annotation databases

EnsembliENSMUST00000021243; ENSMUSP00000021243; ENSMUSG00000020873 [P97858-1]
GeneIDi110172
KEGGimmu:110172
UCSCiuc007lah.1 mouse [P97858-1]

Keywords - Coding sequence diversityi

Alternative splicing

Similar proteinsi

Entry informationi

Entry nameiS35B1_MOUSE
AccessioniPrimary (citable) accession number: P97858
Secondary accession number(s): Q8CF70
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 22, 2005
Last sequence update: May 1, 1997
Last modified: April 25, 2018
This is version 121 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health