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Protein
Submitted name:

Ankyrin

Gene

Ank2

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  • receptor binding Source: BHF-UCL
  • structural constituent of cytoskeleton Source: RGD

GO - Biological processi

  • nervous system development Source: RGD
  • paranodal junction assembly Source: RGD
  • response to methylmercury Source: RGD
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
AnkyrinImported
Gene namesi
Name:Ank2Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

Organism-specific databases

RGDi620156. Ank2.

Subcellular locationi

GO - Cellular componenti

  • cytoskeleton Source: RGD
  • membrane raft Source: RGD
  • neuron projection Source: RGD
  • plasma membrane Source: RGD
Complete GO annotation...

PTM / Processingi

PTM databases

PhosphoSiteiP97582.

Interactioni

GO - Molecular functioni

  • receptor binding Source: BHF-UCL

Protein-protein interaction databases

DIPiDIP-53073N.

Structurei

3D structure databases

ProteinModelPortaliP97582.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini1 – 778778ANK_REP_REGIONInterPro annotationAdd
BLAST

Sequence similaritiesi

Contains 20 ANK repeats.UniRule annotation

Keywords - Domaini

ANK repeatUniRule annotation

Phylogenomic databases

HOGENOMiHOG000169277.
PhylomeDBiP97582.

Family and domain databases

Gene3Di1.25.40.20. 3 hits.
InterProiIPR030301. Ankyrin-B.
IPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
[Graphical view]
PANTHERiPTHR24123:SF17. PTHR24123:SF17. 1 hit.
PfamiPF00023. Ank. 2 hits.
PF12796. Ank_2. 6 hits.
[Graphical view]
PRINTSiPR01415. ANKYRIN.
SMARTiSM00248. ANK. 22 hits.
[Graphical view]
SUPFAMiSSF48403. SSF48403. 3 hits.
PROSITEiPS50297. ANK_REP_REGION. 1 hit.
PS50088. ANK_REPEAT. 20 hits.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

P97582-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
LRAARAGNLD KVVEYLKGGI DINTCNQNGL NALHLAAKEG HVGLVQELLG
60 70 80 90 100
RGSSVDSATK KGNTALHIAS LAGQAEVVKV LVKEGANINA QSQNGFTPLY
110 120 130 140 150
MAAQENHIDV VKYLLENGAN QSTATEDGFT PLAVALQQGH NQAVAILLEN
160 170 180 190 200
DTKGKVRLPA LHIAARKDDT KSAALLLQND HNADVQSKMM VNRTTESGFT
210 220 230 240 250
PLHIAAHYGN VNVATLLLNR GAAVDFTARN GITPLHVASK RGNTNMVKLL
260 270 280 290 300
LDRGGQIDAK TRDGLTPLHC AARSGHDQVV ELLLERGAPL LARTKNGLSP
310 320 330 340 350
LHMAAQGDHV ECVKHLLQHK APVDDVTLDY LTALHVAAHC GHYRVTKLLL
360 370 380 390 400
DKRANPNARA LNGFTPLHIA CKKNRIKVME LLVKYGAYIQ AITESGLTPI
410 420 430 440 450
PVAAFMGHLN IVLLLLQNGA SPDVTNIRGE TALHMAARAG EVEVVRCLLR
460 470 480 490 500
NGALVDARAR EEQTPLHIAS RLGKTEIVQL LLQHMAHPDA ATTNGYTPLH
510 520 530 540 550
ISAREGQVDV ASVLLEAGAA HSLATKKGFT PLHVAAKYGS LDVAKLLLQR
560 570 580 590 600
RAAADSAGKN GLTPLHVAAH YDNQKVALLL LEKGASPHAT AKNGYTPLHI
610 620 630 640 650
AAKKNQMQIA STLLNYGAET NTVTKQGVTP LHLASQEGHT DMVTLVLEKG
660 670 680 690 700
ANIHMSTKSG LTSLHLAAEE DKVNVADILT KHGADQDAYT KLGYTPLIVA
710 720 730 740 750
CHYGNVKMVN FLLKQGANVN AKTKNGYTPL HQAAQQGHTH IINVLLQHGA
760 770 780 790 800
KPNATTANGN TALAIAKRLG YISVVDTLKV VTEEVTTTTT TITEKHKLNA
810 820 830 840
PETMTEVLDV SDEEGDDTVT GDGGEYLRPE DLKELGDDSL PSS
Length:843
Mass (Da):89,983
Last modified:May 1, 1997 - v1
Checksum:iDC5A6AC78825D223
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported
Non-terminal residuei843 – 8431Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U65916 mRNA. Translation: AAB47551.1.
UniGeneiRn.232442.

Genome annotation databases

UCSCiRGD:620156. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U65916 mRNA. Translation: AAB47551.1.
UniGeneiRn.232442.

3D structure databases

ProteinModelPortaliP97582.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

DIPiDIP-53073N.

PTM databases

PhosphoSiteiP97582.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

UCSCiRGD:620156. rat.

Organism-specific databases

RGDi620156. Ank2.

Phylogenomic databases

HOGENOMiHOG000169277.
PhylomeDBiP97582.

Family and domain databases

Gene3Di1.25.40.20. 3 hits.
InterProiIPR030301. Ankyrin-B.
IPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
[Graphical view]
PANTHERiPTHR24123:SF17. PTHR24123:SF17. 1 hit.
PfamiPF00023. Ank. 2 hits.
PF12796. Ank_2. 6 hits.
[Graphical view]
PRINTSiPR01415. ANKYRIN.
SMARTiSM00248. ANK. 22 hits.
[Graphical view]
SUPFAMiSSF48403. SSF48403. 3 hits.
PROSITEiPS50297. ANK_REP_REGION. 1 hit.
PS50088. ANK_REPEAT. 20 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Rat brain ankyrin membrane binding domain."
    Cosentino M.T., Jones O.T.
    Submitted (AUG-1996) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: WistarImported.
    Tissue: BrainImported.

Entry informationi

Entry nameiP97582_RAT
AccessioniPrimary (citable) accession number: P97582
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 1997
Last sequence update: May 1, 1997
Last modified: May 11, 2016
This is version 92 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.