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Protein
Submitted name:

Ankyrin

Gene

Ank2

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  • receptor binding Source: BHF-UCL
  • structural constituent of cytoskeleton Source: RGD

GO - Biological processi

  • nervous system development Source: RGD
  • paranodal junction assembly Source: RGD
  • response to methylmercury Source: RGD

Names & Taxonomyi

Protein namesi
Submitted name:
AnkyrinImported
Gene namesi
Name:Ank2Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus

Organism-specific databases

RGDi620156. Ank2.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

PTM databases

PhosphoSitePlusiP97582.

Interactioni

GO - Molecular functioni

  • receptor binding Source: BHF-UCL

Protein-protein interaction databases

CORUMiP97582.
DIPiDIP-53073N.

Structurei

3D structure databases

ProteinModelPortaliP97582.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 778ANK_REP_REGIONInterPro annotationAdd BLAST778
Repeati28 – 60ANKPROSITE-ProRule annotationAdd BLAST33
Repeati61 – 93ANKPROSITE-ProRule annotationAdd BLAST33
Repeati94 – 126ANKPROSITE-ProRule annotationAdd BLAST33
Repeati197 – 229ANKPROSITE-ProRule annotationAdd BLAST33
Repeati230 – 262ANKPROSITE-ProRule annotationAdd BLAST33
Repeati263 – 295ANKPROSITE-ProRule annotationAdd BLAST33
Repeati296 – 328ANKPROSITE-ProRule annotationAdd BLAST33
Repeati329 – 361ANKPROSITE-ProRule annotationAdd BLAST33
Repeati362 – 394ANKPROSITE-ProRule annotationAdd BLAST33
Repeati395 – 427ANKPROSITE-ProRule annotationAdd BLAST33
Repeati428 – 460ANKPROSITE-ProRule annotationAdd BLAST33
Repeati461 – 493ANKPROSITE-ProRule annotationAdd BLAST33
Repeati494 – 526ANKPROSITE-ProRule annotationAdd BLAST33
Repeati527 – 559ANKPROSITE-ProRule annotationAdd BLAST33
Repeati560 – 592ANKPROSITE-ProRule annotationAdd BLAST33
Repeati593 – 625ANKPROSITE-ProRule annotationAdd BLAST33
Repeati626 – 658ANKPROSITE-ProRule annotationAdd BLAST33
Repeati659 – 691ANKPROSITE-ProRule annotationAdd BLAST33
Repeati692 – 724ANKPROSITE-ProRule annotationAdd BLAST33
Repeati725 – 757ANKPROSITE-ProRule annotationAdd BLAST33

Keywords - Domaini

ANK repeatPROSITE-ProRule annotation

Phylogenomic databases

HOGENOMiHOG000169277.
PhylomeDBiP97582.

Family and domain databases

CDDicd00204. ANK. 6 hits.
Gene3Di1.25.40.20. 11 hits.
InterProiView protein in InterPro
IPR030301. Ankyrin-B.
IPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
PANTHERiPTHR24123:SF34. PTHR24123:SF34. 1 hit.
PfamiView protein in Pfam
PF00023. Ank. 2 hits.
PF12796. Ank_2. 6 hits.
PRINTSiPR01415. ANKYRIN.
SMARTiView protein in SMART
SM00248. ANK. 22 hits.
SUPFAMiSSF48403. SSF48403. 3 hits.
PROSITEiView protein in PROSITE
PS50297. ANK_REP_REGION. 1 hit.
PS50088. ANK_REPEAT. 20 hits.

Sequencei

Sequence statusi: Fragment.

P97582-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
LRAARAGNLD KVVEYLKGGI DINTCNQNGL NALHLAAKEG HVGLVQELLG
60 70 80 90 100
RGSSVDSATK KGNTALHIAS LAGQAEVVKV LVKEGANINA QSQNGFTPLY
110 120 130 140 150
MAAQENHIDV VKYLLENGAN QSTATEDGFT PLAVALQQGH NQAVAILLEN
160 170 180 190 200
DTKGKVRLPA LHIAARKDDT KSAALLLQND HNADVQSKMM VNRTTESGFT
210 220 230 240 250
PLHIAAHYGN VNVATLLLNR GAAVDFTARN GITPLHVASK RGNTNMVKLL
260 270 280 290 300
LDRGGQIDAK TRDGLTPLHC AARSGHDQVV ELLLERGAPL LARTKNGLSP
310 320 330 340 350
LHMAAQGDHV ECVKHLLQHK APVDDVTLDY LTALHVAAHC GHYRVTKLLL
360 370 380 390 400
DKRANPNARA LNGFTPLHIA CKKNRIKVME LLVKYGAYIQ AITESGLTPI
410 420 430 440 450
PVAAFMGHLN IVLLLLQNGA SPDVTNIRGE TALHMAARAG EVEVVRCLLR
460 470 480 490 500
NGALVDARAR EEQTPLHIAS RLGKTEIVQL LLQHMAHPDA ATTNGYTPLH
510 520 530 540 550
ISAREGQVDV ASVLLEAGAA HSLATKKGFT PLHVAAKYGS LDVAKLLLQR
560 570 580 590 600
RAAADSAGKN GLTPLHVAAH YDNQKVALLL LEKGASPHAT AKNGYTPLHI
610 620 630 640 650
AAKKNQMQIA STLLNYGAET NTVTKQGVTP LHLASQEGHT DMVTLVLEKG
660 670 680 690 700
ANIHMSTKSG LTSLHLAAEE DKVNVADILT KHGADQDAYT KLGYTPLIVA
710 720 730 740 750
CHYGNVKMVN FLLKQGANVN AKTKNGYTPL HQAAQQGHTH IINVLLQHGA
760 770 780 790 800
KPNATTANGN TALAIAKRLG YISVVDTLKV VTEEVTTTTT TITEKHKLNA
810 820 830 840
PETMTEVLDV SDEEGDDTVT GDGGEYLRPE DLKELGDDSL PSS
Length:843
Mass (Da):89,983
Last modified:May 1, 1997 - v1
Checksum:iDC5A6AC78825D223
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1
Non-terminal residuei843Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U65916 mRNA. Translation: AAB47551.1.
UniGeneiRn.232442.

Genome annotation databases

UCSCiRGD:620156. rat.

Similar proteinsi

Entry informationi

Entry nameiP97582_RAT
AccessioniPrimary (citable) accession number: P97582
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 1997
Last sequence update: May 1, 1997
Last modified: September 27, 2017
This is version 99 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)