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Protein
Submitted name:

Beta-galactoside alpha-1,2-fucosyltransferase

Gene

Fut1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  • galactoside 2-alpha-L-fucosyltransferase activity Source: MGI

GO - Biological processi

  • fucosylation Source: MGI
  • protein glycosylation Source: GO_Central
Complete GO annotation...

Keywords - Molecular functioni

GlycosyltransferaseImported, Transferase

Enzyme and pathway databases

BRENDAi2.4.1.69. 3474.

Protein family/group databases

CAZyiGT11. Glycosyltransferase Family 11.

Names & Taxonomyi

Protein namesi
Submitted name:
Beta-galactoside alpha-1,2-fucosyltransferaseImported (EC:2.4.1.69Imported)
Submitted name:
GDP-L-fucose:beta-D-galactoside 2-alpha-L-fucosyltransferase FUT-IImported (EC:2.4.1.69Imported)
Submitted name:
Galactoside 2-alpha-L-fucosyltransferase 1Imported
Submitted name:
MCG23182Imported
Gene namesi
Name:Fut1Imported
Synonyms:FUT1Imported, HImported
ORF Names:mCG_23182Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589 Componenti: Chromosome 7

Organism-specific databases

MGIiMGI:109375. Fut1.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000008605.

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00390000001450.
HOGENOMiHOG000261621.
HOVERGENiHBG004338.
KOiK00718.
OMAiFLHIHQD.
OrthoDBiEOG7C5M8F.
TreeFamiTF315810.

Family and domain databases

InterProiIPR002516. Glyco_trans_11.
[Graphical view]
PANTHERiPTHR11927. PTHR11927. 1 hit.
PfamiPF01531. Glyco_transf_11. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P97327-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MWTPSRRQLC LAFLLVCVLS AGSFFFHLNG GNFFRNGLTL SVLCSDYHLL
60 70 80 90 100
KSPVAMVCLP HPLQTSNGSP SCPEQSSSLS GTWTITPGGR FGNQMGQYAT
110 120 130 140 150
LLALAQLNGR QAFIQPEMHA ALAPVFRISL PVLDPEVDSL TPWQHLVLHD
160 170 180 190 200
WMSEEYSHLE DPFLKLSGFP CSWTFFHHLR EQIRREFTLH NHLREGAQYL
210 220 230 240 250
LSGLRIGPAG IRPHTFVGVH VRRGDYLEVM PNRWKGVVGD RAYLQQAMDW
260 270 280 290 300
FRARHKDPIF VVTSNGMKWC LENIDTSHGD VVFAGNGQEG TPGKDFALLT
310 320 330 340 350
QCNHTIMTIG TFGFWAAYLA GGDTVYLANF TLPDSEFLKI FRPEAAFLPE
360 370
WVGINADLSP LQAQFDPWKP DSLFRLV
Length:377
Mass (Da):42,394
Last modified:May 1, 1997 - v1
Checksum:i9B17542B1F7A969A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC149057 Genomic DNA. No translation available.
AF113533 mRNA. Translation: AAD25352.1.
AB039104 Genomic DNA. Translation: BAB68628.1.
AB039105 Genomic DNA. Translation: BAB68629.1.
AB039109 Genomic DNA. Translation: BAB68633.1.
AB039111 Genomic DNA. Translation: BAB68635.1.
AB039112 Genomic DNA. Translation: BAB68636.1.
AK137638 mRNA. Translation: BAE23444.1.
Y09883 Genomic DNA. Translation: CAA71009.1.
CH466603 Genomic DNA. Translation: EDL22877.1.
RefSeqiNP_001258910.1. NM_001271981.1.
NP_032077.2. NM_008051.6.
XP_006540679.1. XM_006540616.2.
UniGeneiMm.491495.
Mm.56933.

Genome annotation databases

EnsembliENSMUST00000008605; ENSMUSP00000008605; ENSMUSG00000008461.
GeneIDi14343.
KEGGimmu:14343.
UCSCiuc009gwg.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC149057 Genomic DNA. No translation available.
AF113533 mRNA. Translation: AAD25352.1.
AB039104 Genomic DNA. Translation: BAB68628.1.
AB039105 Genomic DNA. Translation: BAB68629.1.
AB039109 Genomic DNA. Translation: BAB68633.1.
AB039111 Genomic DNA. Translation: BAB68635.1.
AB039112 Genomic DNA. Translation: BAB68636.1.
AK137638 mRNA. Translation: BAE23444.1.
Y09883 Genomic DNA. Translation: CAA71009.1.
CH466603 Genomic DNA. Translation: EDL22877.1.
RefSeqiNP_001258910.1. NM_001271981.1.
NP_032077.2. NM_008051.6.
XP_006540679.1. XM_006540616.2.
UniGeneiMm.491495.
Mm.56933.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000008605.

Protein family/group databases

CAZyiGT11. Glycosyltransferase Family 11.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000008605; ENSMUSP00000008605; ENSMUSG00000008461.
GeneIDi14343.
KEGGimmu:14343.
UCSCiuc009gwg.1. mouse.

Organism-specific databases

CTDi2523.
MGIiMGI:109375. Fut1.

Phylogenomic databases

GeneTreeiENSGT00390000001450.
HOGENOMiHOG000261621.
HOVERGENiHBG004338.
KOiK00718.
OMAiFLHIHQD.
OrthoDBiEOG7C5M8F.
TreeFamiTF315810.

Enzyme and pathway databases

BRENDAi2.4.1.69. 3474.

Miscellaneous databases

NextBioi285781.
SOURCEiSearch...

Family and domain databases

InterProiIPR002516. Glyco_trans_11.
[Graphical view]
PANTHERiPTHR11927. PTHR11927. 1 hit.
PfamiPF01531. Glyco_transf_11. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Molecular cloning and expression of a mouse GDP-L-Fucose: beta-D-Galactoside 2-alpha-L-Fucosyltransferase."
    Hitoshi S., Kusunoki S., Kanazawa I., Tsuji S.
    Submitted (DEC-1996) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: ICRImported.
    Tissue: BrainImported.
  2. "High-efficiency full-length cDNA cloning."
    Carninci P., Hayashizaki Y.
    Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: VaginaImported.
  3. "GDP-fucose: beta-galactoside alpha1,2-fucosyltransferase, MFUT-II, and not MFUT-I or -III, is induced in a restricted region of the digestive tract of germ-free mice by host-microbe interactions and cycloheximide."
    Lin B., Hayashi Y., Saito M., Sakakibara Y., Yanagisawa M., Iwamori M.
    Biochim. Biophys. Acta 1487:275-285(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: ICRImported.
    Tissue: Gastrointestinal tractImported.
  4. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
    Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
    Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: VaginaImported.
  5. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: VaginaImported.
  6. "Functional annotation of a full-length mouse cDNA collection."
    The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
    Nature 409:685-690(2001)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: VaginaImported.
  7. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
    The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
    Nature 420:563-573(2002)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: VaginaImported.
  8. "A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome."
    Mural R.J., Adams M.D., Myers E.W., Smith H.O., Miklos G.L., Wides R., Halpern A., Li P.W., Sutton G.G., Nadeau J., Salzberg S.L., Holt R.A., Kodira C.D., Lu F., Chen L., Deng Z., Evangelista C.C., Gan W.
    , Heiman T.J., Li J., Li Z., Merkulov G.V., Milshina N.V., Naik A.K., Qi R., Shue B.C., Wang A., Wang J., Wang X., Yan X., Ye J., Yooseph S., Zhao Q., Zheng L., Zhu S.C., Biddick K., Bolanos R., Delcher A.L., Dew I.M., Fasulo D., Flanigan M.J., Huson D.H., Kravitz S.A., Miller J.R., Mobarry C.M., Reinert K., Remington K.A., Zhang Q., Zheng X.H., Nusskern D.R., Lai Z., Lei Y., Zhong W., Yao A., Guan P., Ji R.R., Gu Z., Wang Z.Y., Zhong F., Xiao C., Chiang C.C., Yandell M., Wortman J.R., Amanatides P.G., Hladun S.L., Pratts E.C., Johnson J.E., Dodson K.L., Woodford K.J., Evans C.A., Gropman B., Rusch D.B., Venter E., Wang M., Smith T.J., Houck J.T., Tompkins D.E., Haynes C., Jacob D., Chin S.H., Allen D.R., Dahlke C.E., Sanders R., Li K., Liu X., Levitsky A.A., Majoros W.H., Chen Q., Xia A.C., Lopez J.R., Donnelly M.T., Newman M.H., Glodek A., Kraft C.L., Nodell M., Ali F., An H.J., Baldwin-Pitts D., Beeson K.Y., Cai S., Carnes M., Carver A., Caulk P.M., Center A., Chen Y.H., Cheng M.L., Coyne M.D., Crowder M., Danaher S., Davenport L.B., Desilets R., Dietz S.M., Doup L., Dullaghan P., Ferriera S., Fosler C.R., Gire H.C., Gluecksmann A., Gocayne J.D., Gray J., Hart B., Haynes J., Hoover J., Howland T., Ibegwam C., Jalali M., Johns D., Kline L., Ma D.S., MacCawley S., Magoon A., Mann F., May D., McIntosh T.C., Mehta S., Moy L., Moy M.C., Murphy B.J., Murphy S.D., Nelson K.A., Nuri Z., Parker K.A., Prudhomme A.C., Puri V.N., Qureshi H., Raley J.C., Reardon M.S., Regier M.A., Rogers Y.H., Romblad D.L., Schutz J., Scott J.L., Scott R., Sitter C.D., Smallwood M., Sprague A.C., Stewart E., Strong R.V., Suh E., Sylvester K., Thomas R., Tint N.N., Tsonis C., Wang G., Wang G., Williams M.S., Williams S.M., Windsor S.M., Wolfe K., Wu M.M., Zaveri J., Chaturvedi K., Gabrielian A.E., Ke Z., Sun J., Subramanian G., Venter J.C., Pfannkoch C.M., Barnstead M., Stephenson L.D.
    Science 296:1661-1671(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: MixedImported.
  9. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: VaginaImported.
  10. "The Transcriptional Landscape of the Mammalian Genome."
    The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
    Science 309:1559-1563(2005)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: VaginaImported.
  11. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: VaginaImported.
  12. Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.
    Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: MixedImported.
  13. "Mosaic genealogy of the Mus musculus genome revealed by 21 nuclear genes from its three subspecies."
    Liu Y., Takahashi A., Kitano T., Koide T., Shiroishi T., Moriwaki K., Saitou N.
    Genes Genet. Syst. 83:77-88(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: BFM/2MsfImported, C57BL/10SnJImported, HMI/MsfImported, NJL/MsfImported and Pgn2Imported.
  14. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  15. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiP97327_MOUSE
AccessioniPrimary (citable) accession number: P97327
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 1997
Last sequence update: May 1, 1997
Last modified: June 24, 2015
This is version 98 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.